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Items: 1 to 50 of 56

1.

Characterization of GH2 and GH42 β-galactosidases derived from bifidobacterial infant isolates.

Ambrogi V, Bottacini F, O'Sullivan J, O'Connell Motherway M, Linqiu C, Schoemaker B, Schoterman M, van Sinderen D.

AMB Express. 2019 Jan 19;9(1):9. doi: 10.1186/s13568-019-0735-3.

2.

A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation.

O'Connell Motherway M, Houston A, O'Callaghan G, Reunanen J, O'Brien F, O'Driscoll T, Casey PG, de Vos WM, van Sinderen D, Shanahan F.

Mol Microbiol. 2019 Jan;111(1):287-301. doi: 10.1111/mmi.14155. Epub 2018 Dec 2.

PMID:
30352131
3.

Staying alive: growth and survival of Bifidobacterium animalis subsp. animalis under in vitro and in vivo conditions.

Egan M, Bottacini F, O'Connell Motherway M, Casey PG, Morrissey R, Melgar S, Faurie JM, Chervaux C, Smokvina T, van Sinderen D.

Appl Microbiol Biotechnol. 2018 Dec;102(24):10645-10663. doi: 10.1007/s00253-018-9413-7. Epub 2018 Oct 10.

PMID:
30306201
4.

Comparative genomics and genotype-phenotype associations in Bifidobacterium breve.

Bottacini F, Morrissey R, Esteban-Torres M, James K, van Breen J, Dikareva E, Egan M, Lambert J, van Limpt K, Knol J, O'Connell Motherway M, van Sinderen D.

Sci Rep. 2018 Jul 13;8(1):10633. doi: 10.1038/s41598-018-28919-4.

5.

Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut.

O'Connell Motherway M, O'Brien F, O'Driscoll T, Casey PG, Shanahan F, van Sinderen D.

Sci Rep. 2018 Jul 13;8(1):10627. doi: 10.1038/s41598-018-29034-0.

6.

Bifidobacterium breve UCC2003 Employs Multiple Transcriptional Regulators To Control Metabolism of Particular Human Milk Oligosaccharides.

James K, O'Connell Motherway M, Penno C, O'Brien RL, van Sinderen D.

Appl Environ Microbiol. 2018 Apr 16;84(9). pii: e02774-17. doi: 10.1128/AEM.02774-17. Print 2018 May 1.

7.

Gene-trait matching across the Bifidobacterium longum pan-genome reveals considerable diversity in carbohydrate catabolism among human infant strains.

Arboleya S, Bottacini F, O'Connell-Motherway M, Ryan CA, Ross RP, van Sinderen D, Stanton C.

BMC Genomics. 2018 Jan 8;19(1):33. doi: 10.1186/s12864-017-4388-9.

8.

Identification of probiotic effector molecules: present state and future perspectives.

Lebeer S, Bron PA, Marco ML, Van Pijkeren JP, O'Connell Motherway M, Hill C, Pot B, Roos S, Klaenhammer T.

Curr Opin Biotechnol. 2018 Feb;49:217-223. doi: 10.1016/j.copbio.2017.10.007. Epub 2017 Nov 16. Review.

PMID:
29153882
9.

The essential genomic landscape of the commensal Bifidobacterium breve UCC2003.

Ruiz L, Bottacini F, Boinett CJ, Cain AK, O'Connell-Motherway M, Lawley TD, van Sinderen D.

Sci Rep. 2017 Jul 17;7(1):5648. doi: 10.1038/s41598-017-05795-y.

10.

Genome-Wide Search for Genes Required for Bifidobacterial Growth under Iron-Limitation.

Lanigan N, Bottacini F, Casey PG, O'Connell Motherway M, van Sinderen D.

Front Microbiol. 2017 May 31;8:964. doi: 10.3389/fmicb.2017.00964. eCollection 2017.

11.

The Surface-Associated Exopolysaccharide of Bifidobacterium longum 35624 Plays an Essential Role in Dampening Host Proinflammatory Responses and Repressing Local TH17 Responses.

Schiavi E, Gleinser M, Molloy E, Groeger D, Frei R, Ferstl R, Rodriguez-Perez N, Ziegler M, Grant R, Moriarty TF, Plattner S, Healy S, O'Connell Motherway M, Akdis CA, Roper J, Altmann F, van Sinderen D, O'Mahony L.

Appl Environ Microbiol. 2016 Nov 21;82(24):7185-7196. Print 2016 Dec 15.

12.

Glycosulfatase-Encoding Gene Cluster in Bifidobacterium breve UCC2003.

Egan M, Jiang H, O'Connell Motherway M, Oscarson S, van Sinderen D.

Appl Environ Microbiol. 2016 Oct 27;82(22):6611-6623. Print 2016 Nov 15.

13.

Genome Analysis and Characterisation of the Exopolysaccharide Produced by Bifidobacterium longum subsp. longum 35624™.

Altmann F, Kosma P, O'Callaghan A, Leahy S, Bottacini F, Molloy E, Plattner S, Schiavi E, Gleinser M, Groeger D, Grant R, Rodriguez Perez N, Healy S, Svehla E, Windwarder M, Hofinger A, O'Connell Motherway M, Akdis CA, Xu J, Roper J, van Sinderen D, O'Mahony L.

PLoS One. 2016 Sep 22;11(9):e0162983. doi: 10.1371/journal.pone.0162983. eCollection 2016.

14.

Cloning, expression and characterization of a β-D-xylosidase from Lactobacillus rossiae DSM 15814(T).

Pontonio E, Mahony J, Di Cagno R, O'Connell Motherway M, Lugli GA, O'Callaghan A, De Angelis M, Ventura M, Gobbetti M, van Sinderen D.

Microb Cell Fact. 2016 May 3;15:72. doi: 10.1186/s12934-016-0473-z.

15.

Pangenome analysis of Bifidobacterium longum and site-directed mutagenesis through by-pass of restriction-modification systems.

O'Callaghan A, Bottacini F, O'Connell Motherway M, van Sinderen D.

BMC Genomics. 2015 Oct 21;16:832. doi: 10.1186/s12864-015-1968-4.

16.

Productive mRNA stem loop-mediated transcriptional slippage: Crucial features in common with intrinsic terminators.

Penno C, Sharma V, Coakley A, O'Connell Motherway M, van Sinderen D, Lubkowska L, Kireeva ML, Kashlev M, Baranov PV, Atkins JF.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E1984-93. doi: 10.1073/pnas.1418384112. Epub 2015 Apr 6.

17.

A GntR-type transcriptional repressor controls sialic acid utilization in Bifidobacterium breve UCC2003.

Egan M, O'Connell Motherway M, van Sinderen D.

FEMS Microbiol Lett. 2015 Feb;362(4). doi: 10.1093/femsle/fnu056. Epub 2014 Dec 11.

18.

Discovery of a conjugative megaplasmid in Bifidobacterium breve.

Bottacini F, O'Connell Motherway M, Casey E, McDonnell B, Mahony J, Ventura M, van Sinderen D.

Appl Environ Microbiol. 2015 Jan;81(1):166-76. doi: 10.1128/AEM.02871-14. Epub 2014 Oct 17.

19.

Methyltransferases acquired by lactococcal 936-type phage provide protection against restriction endonuclease activity.

Murphy J, Klumpp J, Mahony J, O'Connell-Motherway M, Nauta A, van Sinderen D.

BMC Genomics. 2014 Oct 1;15:831. doi: 10.1186/1471-2164-15-831.

20.

Diversity, ecology and intestinal function of bifidobacteria.

Bottacini F, Ventura M, van Sinderen D, O'Connell Motherway M.

Microb Cell Fact. 2014 Aug 29;13 Suppl 1:S4. doi: 10.1186/1475-2859-13-S1-S4. Epub 2014 Aug 29. Review.

21.

Molecular characterization of three Lactobacillus delbrueckii subsp. bulgaricus phages.

Casey E, Mahony J, O'Connell-Motherway M, Bottacini F, Cornelissen A, Neve H, Heller KJ, Noben JP, Dal Bello F, van Sinderen D.

Appl Environ Microbiol. 2014 Sep;80(18):5623-35. doi: 10.1128/AEM.01268-14. Epub 2014 Jul 7.

22.

Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003.

Christiaen SE, O'Connell Motherway M, Bottacini F, Lanigan N, Casey PG, Huys G, Nelis HJ, van Sinderen D, Coenye T.

PLoS One. 2014 May 28;9(5):e98111. doi: 10.1371/journal.pone.0098111. eCollection 2014.

23.

Metabolism of sialic acid by Bifidobacterium breve UCC2003.

Egan M, O'Connell Motherway M, Ventura M, van Sinderen D.

Appl Environ Microbiol. 2014 Jul;80(14):4414-26. doi: 10.1128/AEM.01114-14. Epub 2014 May 9.

24.

Comparative genomics of the Bifidobacterium breve taxon.

Bottacini F, O'Connell Motherway M, Kuczynski J, O'Connell KJ, Serafini F, Duranti S, Milani C, Turroni F, Lugli GA, Zomer A, Zhurina D, Riedel C, Ventura M, van Sinderen D.

BMC Genomics. 2014 Mar 1;15:170. doi: 10.1186/1471-2164-15-170.

25.

In silico assigned resistance genes confer Bifidobacterium with partial resistance to aminoglycosides but not to β-lactams.

Fouhy F, O'Connell Motherway M, Fitzgerald GF, Ross RP, Stanton C, van Sinderen D, Cotter PD.

PLoS One. 2013 Dec 6;8(12):e82653. doi: 10.1371/journal.pone.0082653. eCollection 2013.

26.

Metabolism of four α-glycosidic linkage-containing oligosaccharides by Bifidobacterium breve UCC2003.

O'Connell KJ, O'Connell Motherway M, O'Callaghan J, Fitzgerald GF, Ross RP, Ventura M, Stanton C, van Sinderen D.

Appl Environ Microbiol. 2013 Oct;79(20):6280-92. doi: 10.1128/AEM.01775-13. Epub 2013 Aug 2.

27.

Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions.

Turroni F, Serafini F, Foroni E, Duranti S, O'Connell Motherway M, Taverniti V, Mangifesta M, Milani C, Viappiani A, Roversi T, Sánchez B, Santoni A, Gioiosa L, Ferrarini A, Delledonne M, Margolles A, Piazza L, Palanza P, Bolchi A, Guglielmetti S, van Sinderen D, Ventura M.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11151-6. doi: 10.1073/pnas.1303897110. Epub 2013 Jun 17.

28.

Selective carbohydrate utilization by lactobacilli and bifidobacteria.

Watson D, O'Connell Motherway M, Schoterman MH, van Neerven RJ, Nauta A, van Sinderen D.

J Appl Microbiol. 2013 Apr;114(4):1132-46. doi: 10.1111/jam.12105. Epub 2013 Jan 11.

29.

Transcriptional and functional characterization of genetic elements involved in galacto-oligosaccharide utilization by Bifidobacterium breve UCC2003.

O'Connell Motherway M, Kinsella M, Fitzgerald GF, van Sinderen D.

Microb Biotechnol. 2013 Jan;6(1):67-79. doi: 10.1111/1751-7915.12011. Epub 2012 Dec 2.

30.

A two-component regulatory system controls autoregulated serpin expression in Bifidobacterium breve UCC2003.

Alvarez-Martin P, O'Connell Motherway M, Turroni F, Foroni E, Ventura M, van Sinderen D.

Appl Environ Microbiol. 2012 Oct;78(19):7032-41. doi: 10.1128/AEM.01776-12. Epub 2012 Jul 27.

31.

A conserved two-component signal transduction system controls the response to phosphate starvation in Bifidobacterium breve UCC2003.

Alvarez-Martin P, Fernández M, O'Connell-Motherway M, O'Connell KJ, Sauvageot N, Fitzgerald GF, MacSharry J, Zomer A, van Sinderen D.

Appl Environ Microbiol. 2012 Aug;78(15):5258-69. doi: 10.1128/AEM.00804-12. Epub 2012 May 25.

32.

A bile-inducible membrane protein mediates bifidobacterial bile resistance.

Ruiz L, O'Connell-Motherway M, Zomer A, de los Reyes-Gavilán CG, Margolles A, van Sinderen D.

Microb Biotechnol. 2012 Jul;5(4):523-35. doi: 10.1111/j.1751-7915.2011.00329.x. Epub 2012 Feb 1.

33.

Discovering novel bile protection systems in Bifidobacterium breve UCC2003 through functional genomics.

Ruiz L, Zomer A, O'Connell-Motherway M, van Sinderen D, Margolles A.

Appl Environ Microbiol. 2012 Feb;78(4):1123-31. doi: 10.1128/AEM.06060-11. Epub 2011 Dec 9.

34.

Genetic analysis and morphological identification of pilus-like structures in members of the genus Bifidobacterium.

Foroni E, Serafini F, Amidani D, Turroni F, He F, Bottacini F, O'Connell Motherway M, Viappiani A, Zhang Z, Rivetti C, van Sinderen D, Ventura M.

Microb Cell Fact. 2011 Aug 30;10 Suppl 1:S16. doi: 10.1186/1475-2859-10-S1-S16. Epub 2011 Aug 30.

35.

Expanding the molecular toolbox for Lactococcus lactis: construction of an inducible thioredoxin gene fusion expression system.

Douillard FP, O'Connell-Motherway M, Cambillau C, van Sinderen D.

Microb Cell Fact. 2011 Aug 9;10:66. doi: 10.1186/1475-2859-10-66.

36.

Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor.

O'Connell Motherway M, Zomer A, Leahy SC, Reunanen J, Bottacini F, Claesson MJ, O'Brien F, Flynn K, Casey PG, Munoz JA, Kearney B, Houston AM, O'Mahony C, Higgins DG, Shanahan F, Palva A, de Vos WM, Fitzgerald GF, Ventura M, O'Toole PW, van Sinderen D.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11217-22. doi: 10.1073/pnas.1105380108. Epub 2011 Jun 20.

37.

Metabolism of a plant derived galactose-containing polysaccharide by Bifidobacterium breve UCC2003.

O'Connell Motherway M, Fitzgerald GF, van Sinderen D.

Microb Biotechnol. 2011 May;4(3):403-16. doi: 10.1111/j.1751-7915.2010.00218.x. Epub 2010 Oct 21.

38.

Ribose utilization by the human commensal Bifidobacterium breve UCC2003.

Pokusaeva K, Neves AR, Zomer A, O'Connell-Motherway M, MacSharry J, Curley P, Fitzgerald GF, van Sinderen D.

Microb Biotechnol. 2010 May;3(3):311-23. doi: 10.1111/j.1751-7915.2009.00152.x. Epub 2009 Oct 15.

39.

Cellodextrin utilization by bifidobacterium breve UCC2003.

Pokusaeva K, O'Connell-Motherway M, Zomer A, Macsharry J, Fitzgerald GF, van Sinderen D.

Appl Environ Microbiol. 2011 Mar;77(5):1681-90. doi: 10.1128/AEM.01786-10. Epub 2011 Jan 7.

40.

Characterization of the serpin-encoding gene of Bifidobacterium breve 210B.

Turroni F, Foroni E, O'Connell Motherway M, Bottacini F, Giubellini V, Zomer A, Ferrarini A, Delledonne M, Zhang Z, van Sinderen D, Ventura M.

Appl Environ Microbiol. 2010 May;76(10):3206-19. doi: 10.1128/AEM.02938-09. Epub 2010 Mar 26.

41.

Overcoming the restriction barrier to plasmid transformation and targeted mutagenesis in Bifidobacterium breve UCC2003.

O'Connell Motherway M, O'Driscoll J, Fitzgerald GF, Van Sinderen D.

Microb Biotechnol. 2009 May;2(3):321-32. doi: 10.1111/j.1751-7915.2008.00071.x. Epub 2008 Dec 3.

42.

Characterization of two novel alpha-glucosidases from Bifidobacterium breve UCC2003.

Pokusaeva K, O'Connell-Motherway M, Zomer A, Fitzgerald GF, van Sinderen D.

Appl Environ Microbiol. 2009 Feb;75(4):1135-43. doi: 10.1128/AEM.02391-08. Epub 2008 Dec 29.

43.

Characterization of ApuB, an extracellular type II amylopullulanase from Bifidobacterium breve UCC2003.

O'Connell Motherway M, Fitzgerald GF, Neirynck S, Ryan S, Steidler L, van Sinderen D.

Appl Environ Microbiol. 2008 Oct;74(20):6271-9. doi: 10.1128/AEM.01169-08. Epub 2008 Aug 8.

44.

Molecular dissection of a bifidobacterial replicon.

Cronin M, Knobel M, O'Connell-Motherway M, Fitzgerald GF, van Sinderen D.

Appl Environ Microbiol. 2007 Dec;73(24):7858-66. Epub 2007 Oct 26.

45.

Comparative analyses of prophage-like elements present in two Lactococcus lactis strains.

Ventura M, Zomer A, Canchaya C, O'Connell-Motherway M, Kuipers O, Turroni F, Ribbera A, Foroni E, Buist G, Wegmann U, Shearman C, Gasson MJ, Fitzgerald GF, Kok J, van Sinderen D.

Appl Environ Microbiol. 2007 Dec;73(23):7771-80. Epub 2007 Oct 12.

46.

Functional analysis of the pBC1 replicon from Bifidobacterium catenulatum L48.

Alvarez-Martín P, O'Connell-Motherway M, van Sinderen D, Mayo B.

Appl Microbiol Biotechnol. 2007 Oct;76(6):1395-402. Epub 2007 Aug 18.

PMID:
17704917
47.

From bacterial genome to functionality; case bifidobacteria.

Ventura M, O'Connell-Motherway M, Leahy S, Moreno-Munoz JA, Fitzgerald GF, van Sinderen D.

Int J Food Microbiol. 2007 Nov 30;120(1-2):2-12. Epub 2007 Jun 13. Review.

PMID:
17629975
48.

Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363.

Wegmann U, O'Connell-Motherway M, Zomer A, Buist G, Shearman C, Canchaya C, Ventura M, Goesmann A, Gasson MJ, Kuipers OP, van Sinderen D, Kok J.

J Bacteriol. 2007 Apr;189(8):3256-70. Epub 2007 Feb 16.

49.

Identification and characterization of a fructose phosphotransferase system in Bifidobacterium breve UCC2003.

Mazé A, O'Connell-Motherway M, Fitzgerald GF, Deutscher J, van Sinderen D.

Appl Environ Microbiol. 2007 Jan;73(2):545-53. Epub 2006 Nov 10.

50.

Prophage-like elements in bifidobacteria: insights from genomics, transcription, integration, distribution, and phylogenetic analysis.

Ventura M, Lee JH, Canchaya C, Zink R, Leahy S, Moreno-Munoz JA, O'Connell-Motherway M, Higgins D, Fitzgerald GF, O'Sullivan DJ, van Sinderen D.

Appl Environ Microbiol. 2005 Dec;71(12):8692-705.

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