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Palliative Caregivers' Spirituality, Views About Spiritual Care, and Associations With Spiritual Well-Being: A Mixed Methods Study.

O'Callaghan C, Seah D, Clayton JM, Welz M, Kissane D, Georgousopoulou EN, Michael N.

Am J Hosp Palliat Care. 2019 Sep 24:1049909119877351. doi: 10.1177/1049909119877351. [Epub ahead of print]


Disinhibition in Frontotemporal Dementia and Alzheimer's Disease: A Neuropsychological and Behavioural Investigation.

Mariano LI, O'Callaghan C, Guimarães HC, Gambogi LB, da Silva TBL, Yassuda MS, Amaral JS, Caramelli P, Hornberger M, Teixeira AL, de Souza LC.

J Int Neuropsychol Soc. 2019 Sep 23:1-9. doi: 10.1017/S1355617719000973. [Epub ahead of print]


Effects of antihypertensives, lipid-modifying drugs, glycaemic control drugs and sodium bicarbonate on the progression of stages 3 and 4 chronic kidney disease in adults: a systematic review and meta-analysis.

Taylor KS, Mclellan J, Verbakel JY, Aronson JK, Lasserson DS, Pidduck N, Roberts N, Fleming S, O'Callaghan CA, Bankhead CR, Banerjee A, Hobbs FR, Perera R.

BMJ Open. 2019 Sep 20;9(9):e030596. doi: 10.1136/bmjopen-2019-030596.


Reduced kidney function at presentation in unselected acute emergency medical admissions: incidence, outcome and associated factors.

Yang E, Chalisey A, Reschen ME, Shine B, Lasserson DS, O'Callaghan CA.

Acute Med. 2019;18(3):158-164.


Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.

Chen AX, Moran JL, Libianto R, Baqar S, O'Callaghan C, MacIsaac RJ, Jerums G, Ekinci EI.

J Hum Hypertens. 2019 Sep 9. doi: 10.1038/s41371-019-0238-3. [Epub ahead of print]


Accrual of older adults to cancer clinical trials led by the Canadian cancer trials group - Is trial design a barrier?

Hernandez-Torres C, Cheung WY, Kong S, O'Callaghan CJ, Hsu T.

J Geriatr Oncol. 2019 Aug 28. pii: S1879-4068(19)30145-6. doi: 10.1016/j.jgo.2019.08.004. [Epub ahead of print]


A Touchscreen Motivation Assessment Evaluated in Huntington's Disease Patients and R6/1 Model Mice.

Heath CJ, O'Callaghan C, Mason SL, Phillips BU, Saksida LM, Robbins TW, Barker RA, Bussey TJ, Sahakian BJ.

Front Neurol. 2019 Aug 9;10:858. doi: 10.3389/fneur.2019.00858. eCollection 2019.


Inosine pranobex enhances human NK cell cytotoxicity by inducing metabolic activation and NKG2D ligand expression.

McCarthy MT, Lin D, Soga T, Adam J, O'Callaghan CA.

Eur J Immunol. 2019 Aug 21. doi: 10.1002/eji.201847948. [Epub ahead of print]


Characteristics of patients with cancer who die by suicide: Coronial case series in an Australian state.

Dwyer J, Dwyer J, Hiscock R, O'Callaghan C, Taylor K, Ross M, Bugeja L, Philip J.

Psychooncology. 2019 Aug 16. doi: 10.1002/pon.5207. [Epub ahead of print]


Patients' and Caregivers' Contested Perspectives on Spiritual Care for Those Affected by Advanced Illnesses: A Qualitative Descriptive Study.

O'Callaghan C, Brooker J, de Silva W, Glenister D, Melia Cert A 4th, Symons X, Kissane D, Michael N.

J Pain Symptom Manage. 2019 Aug 9. pii: S0885-3924(19)30446-4. doi: 10.1016/j.jpainsymman.2019.08.004. [Epub ahead of print]


Can Administrative Data Improve the Performance of Cancer Clinical Trial Economic Analyses?

Hanna TP, Nguyen P, Pater J, O'Callaghan CJ, Mittmann N, Earle CC, Tu D, Jonker D, Hay AE.

J Oncol Pract. 2019 Sep;15(9):e807-e824. doi: 10.1200/JOP.18.00691. Epub 2019 Jul 15.


A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Fang H; ULTRA-DD Consortium, De Wolf H, Knezevic B, Burnham KL, Osgood J, Sanniti A, Lledó Lara A, Kasela S, De Cesco S, Wegner JK, Handunnetthi L, McCann FE, Chen L, Sekine T, Brennan PE, Marsden BD, Damerell D, O'Callaghan CA, Bountra C, Bowness P, Sundström Y, Milani L, Berg L, Göhlmann HW, Peeters PJ, Fairfax BP, Sundström M, Knight JC.

Nat Genet. 2019 Jul;51(7):1082-1091. doi: 10.1038/s41588-019-0456-1. Epub 2019 Jun 28.


Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD.

Feakins B, Oke J, McFadden E, Aronson J, Lasserson D, O'Callaghan C, Taylor C, Hill N, Stevens R, Perera R.

BMJ Open. 2019 Jun 12;9(6):e028062. doi: 10.1136/bmjopen-2018-028062. Erratum in: BMJ Open. 2019 Jul 1;9(7):e028062corr1.


Meta-analytic Evidence for the Plurality of Mechanisms in Transdiagnostic Structural MRI Studies of Hallucination Status.

Rollins CPE, Garrison JR, Simons JS, Rowe JB, O'Callaghan C, Murray GK, Suckling J.

EClinicalMedicine. 2019 Feb 21;8:57-71. doi: 10.1016/j.eclinm.2019.01.012. eCollection 2019 Feb.


Advantages of the net benefit regression framework for trial-based economic evaluations of cancer treatments: an example from the Canadian Cancer Trials Group CO.17 trial.

Hoch JS, Hay A, Isaranuwatchai W, Thavorn K, Leighl NB, Tu D, Trenaman L, Dewa CS, O'Callaghan C, Pater J, Jonker D, Chen BE, Mittmann N.

BMC Cancer. 2019 Jun 7;19(1):552. doi: 10.1186/s12885-019-5779-x.


Combined Targeting of Estrogen Receptor Alpha and XPO1 Prevent Akt Activation, Remodel Metabolic Pathways and Induce Autophagy to Overcome Tamoxifen Resistance.

Kulkoyluoglu-Cotul E, Smith BP, Wrobel K, Zhao YC, Chen KLA, Hieronymi K, Imir OB, Duong K, O'Callaghan C, Mehta A, Sahoo S, Haley B, Chang H, Landesman Y, Madak-Erdogan Z.

Cancers (Basel). 2019 Apr 4;11(4). pii: E479. doi: 10.3390/cancers11040479.


Changes in structural network topology correlate with severity of hallucinatory behavior in Parkinson's disease.

Hall JM, O'Callaghan C, Muller AJ, Ehgoetz Martens KA, Phillips JR, Moustafa AA, Lewis SJG, Shine JM.

Netw Neurosci. 2019 Mar 1;3(2):521-538. doi: 10.1162/netn_a_00078. eCollection 2019.


A retrospective analysis of outcomes in low- and intermediate-high-risk pulmonary embolism patients managed on an ambulatory medical unit in the UK.

Reschen ME, Raby J, Bowen J, Singh S, Lasserson D, O'Callaghan CA.

ERJ Open Res. 2019 Apr 8;5(2). pii: 00184-2018. doi: 10.1183/23120541.00184-2018. eCollection 2019 Apr.


Dopamine depletion alters macroscopic network dynamics in Parkinson's disease.

Shine JM, Bell PT, Matar E, Poldrack RA, Lewis SJG, Halliday GM, O'Callaghan C.

Brain. 2019 Apr 1;142(4):1024-1034. doi: 10.1093/brain/awz034.


Accuracy of High-Speed Video Analysis to Diagnose Primary Ciliary Dyskinesia.

Rubbo B, Shoemark A, Jackson CL, Hirst R, Thompson J, Hayes J, Frost E, Copeland F, Hogg C, O'Callaghan C, Reading I, Lucas JS; National PCD Service, UK.

Chest. 2019 May;155(5):1008-1017. doi: 10.1016/j.chest.2019.01.036. Epub 2019 Feb 28.


Hippocampal atrophy and intrinsic brain network dysfunction relate to alterations in mind wandering in neurodegeneration.

O'Callaghan C, Shine JM, Hodges JR, Andrews-Hanna JR, Irish M.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3316-3321. doi: 10.1073/pnas.1818523116. Epub 2019 Feb 4.


Timing of palliative care referral and aggressive cancer care toward the end-of-life in pancreatic cancer: a retrospective, single-center observational study.

Michael N, Beale G, O'Callaghan C, Melia A, DeSilva W, Costa D, Kissane D, Shapiro J, Hiscock R.

BMC Palliat Care. 2019 Jan 28;18(1):13. doi: 10.1186/s12904-019-0399-4.


Informant- and Self-Appraisals on the Psychosis and Hallucinations Questionnaire (PsycH-Q) Enhances Detection of Visual Hallucinations in Parkinson's Disease.

Muller AJ, Mills JMZ, O'Callaghan C, Naismith SL, Clouston PD, Lewis SJG, Shine JM.

Mov Disord Clin Pract. 2018 Nov 8;5(6):607-613. doi: 10.1002/mdc3.12683. eCollection 2018 Nov-Dec.


Hypertension as a predictor of advanced colorectal cancer outcome and cetuximab treatment response.

Sud S, O'Callaghan C, Jonker C, Karapetis C, Price T, Tebbutt N, Shapiro J, Van Hazel G, Pavlakis N, Gibbs P, Jeffrey M, Siu L, Gill S, Wong R, Jonker D, Tu D, Goodwin R.

Curr Oncol. 2018 Dec;25(6):e516-e526. doi: 10.3747/co.25.4069. Epub 2018 Dec 1.


Outcomes of Older Patients (≥ 70 Years) Treated With Targeted Therapy in Metastatic Chemorefractory Colorectal Cancer: Retrospective Analysis of NCIC CTG CO.17 and CO.20.

Wells JC, Tu D, Siu LL, Shapiro JD, Jonker DJ, Karapetis C, Simes J, Liu G, Price TJ, Tebbutt NC, O'Callaghan CJ.

Clin Colorectal Cancer. 2019 Mar;18(1):e140-e149. doi: 10.1016/j.clcc.2018.11.006. Epub 2018 Nov 28.


FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer.

Conroy T, Hammel P, Hebbar M, Ben Abdelghani M, Wei AC, Raoul JL, Choné L, Francois E, Artru P, Biagi JJ, Lecomte T, Assenat E, Faroux R, Ychou M, Volet J, Sauvanet A, Breysacher G, Di Fiore F, Cripps C, Kavan P, Texereau P, Bouhier-Leporrier K, Khemissa-Akouz F, Legoux JL, Juzyna B, Gourgou S, O'Callaghan CJ, Jouffroy-Zeller C, Rat P, Malka D, Castan F, Bachet JB; Canadian Cancer Trials Group and the Unicancer-GI–PRODIGE Group.

N Engl J Med. 2018 Dec 20;379(25):2395-2406. doi: 10.1056/NEJMoa1809775.


Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus.

Fassad MR, Shoemark A, Legendre M, Hirst RA, Koll F, le Borgne P, Louis B, Daudvohra F, Patel MP, Thomas L, Dixon M, Burgoyne T, Hayes J, Nicholson AG, Cullup T, Jenkins L, Carr SB, Aurora P, Lemullois M, Aubusson-Fleury A, Papon JF, O'Callaghan C, Amselem S, Hogg C, Escudier E, Tassin AM, Mitchison HM.

Am J Hum Genet. 2018 Dec 6;103(6):984-994. doi: 10.1016/j.ajhg.2018.10.016. Epub 2018 Nov 21.


Pilot study of the ability to probabilistically link clinical trial patients to administrative data and determine long-term outcomes.

Hay AE, Pater JL, Corn E, Han L, Camacho X, O'Callaghan C, Chong N, Bell EN, Tu D, Earle CC.

Clin Trials. 2019 Feb;16(1):14-17. doi: 10.1177/1740774518815653. Epub 2018 Nov 22.


Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.

Walters LC, Harlos K, Brackenridge S, Rozbesky D, Barrett JR, Jain V, Walter TS, O'Callaghan CA, Borrow P, Toebes M, Hansen SG, Sacha JB, Abdulhaqq S, Greene JM, Früh K, Marshall E, Picker LJ, Jones EY, McMichael AJ, Gillespie GM.

Nat Commun. 2018 Nov 13;9(1):4833. doi: 10.1038/s41467-018-07304-9.


[Spanish adaptation of the free OxMaR software for minimization and randomization of clinical studies].

Guillaumes S, O'Callaghan CA.

Gac Sanit. 2019 Jul - Aug;33(4):395-397. doi: 10.1016/j.gaceta.2018.07.013. Epub 2018 Nov 1. Spanish.


Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects.

Bonnefoy S, Watson CM, Kernohan KD, Lemos M, Hutchinson S, Poulter JA, Crinnion LA, Berry I, Simmonds J, Vasudevan P, O'Callaghan C, Hirst RA, Rutman A, Huang L, Hartley T, Grynspan D, Moya E, Li C, Carr IM, Bonthron DT, Leroux M; Care4Rare Canada Consortium, Boycott KM, Bastin P, Sheridan EG.

Am J Hum Genet. 2018 Nov 1;103(5):727-739. doi: 10.1016/j.ajhg.2018.10.003.


Novel Smartphone Interventions Improve Cognitive Flexibility and Obsessive-Compulsive Disorder Symptoms in Individuals with Contamination Fears.

Jalal B, Brühl A, O'Callaghan C, Piercy T, Cardinal RN, Ramachandran VS, Sahakian BJ.

Sci Rep. 2018 Oct 23;8(1):14923. doi: 10.1038/s41598-018-33142-2.


Fc-gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer.

Shepshelovich D, Townsend AR, Espin-Garcia O, Latifovic L, O'Callaghan CJ, Jonker DJ, Tu D, Chen E, Morgen E, Price TJ, Shapiro J, Siu LL, Kubo M, Dobrovic A, Ratain MJ, Xu W, Mushiroda T, Liu G.

Cancer Med. 2018 Nov;7(11):5478-5487. doi: 10.1002/cam4.1819. Epub 2018 Oct 14.


Age-related changes in the temporal focus and self-referential content of spontaneous cognition during periods of low cognitive demand.

Irish M, Goldberg ZL, Alaeddin S, O'Callaghan C, Andrews-Hanna JR.

Psychol Res. 2019 Jun;83(4):747-760. doi: 10.1007/s00426-018-1102-8. Epub 2018 Oct 6.


The Future Is Now-Prospective Study of Radiosurgery for More Than 4 Brain Metastases to Start in 2018!

Roberge D, Brown PD, Whitton A, O'Callaghan C, Leis A, Greenspoon J, Smith GL, Hu JJ, Nichol A, Winch C, Chan MD.

Front Oncol. 2018 Sep 13;8:380. doi: 10.3389/fonc.2018.00380. eCollection 2018.


Risk factors for situs defects and congenital heart disease in primary ciliary dyskinesia.

Best S, Shoemark A, Rubbo B, Patel MP, Fassad MR, Dixon M, Rogers AV, Hirst RA, Rutman A, Ollosson S, Jackson CL, Goggin P, Thomas S, Pengelly R, Cullup T, Pissaridou E, Hayward J, Onoufriadis A, O'Callaghan C, Loebinger MR, Wilson R, Chung EM, Kenia P, Doughty VL, Carvalho JS, Lucas JS, Mitchison HM, Hogg C.

Thorax. 2019 Feb;74(2):203-205. doi: 10.1136/thoraxjnl-2018-212104. Epub 2018 Aug 30.


Macrophage Phagocytosis and Allergen Avoidance in Children With Asthma.

Kulkarni N, Kantar A, Costella S, Ragazzo V, Piacentini G, Boner A, O'Callaghan C.

Front Pediatr. 2018 Aug 2;6:206. doi: 10.3389/fped.2018.00206. eCollection 2018.


Emergence of winner-takes-all connectivity paths in random nanowire networks.

Manning HG, Niosi F, da Rocha CG, Bellew AT, O'Callaghan C, Biswas S, Flowers PF, Wiley BJ, Holmes JD, Ferreira MS, Boland JJ.

Nat Commun. 2018 Aug 13;9(1):3219. doi: 10.1038/s41467-018-05517-6.


Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.

Walters LC, Harlos K, Brackenridge S, Rozbesky D, Barrett JR, Jain V, Walter TS, O'Callaghan CA, Borrow P, Toebes M, Hansen SG, Sacha JB, Abdulhaqq S, Greene JM, Früh K, Marshall E, Picker LJ, Jones EY, McMichael AJ, Gillespie GM.

Nat Commun. 2018 Aug 7;9(1):3137. doi: 10.1038/s41467-018-05459-z. Erratum in: Nat Commun. 2018 Nov 13;9(1):4833.


An audit of discharge summaries from secondary to primary care.

O'Connor R, O'Callaghan C, McNamara R, Salim U.

Ir J Med Sci. 2019 May;188(2):537-540. doi: 10.1007/s11845-018-1862-6. Epub 2018 Jul 17.


MetClo: methylase-assisted hierarchical DNA assembly using a single type IIS restriction enzyme.

Lin D, O'Callaghan CA.

Nucleic Acids Res. 2018 Nov 2;46(19):e113. doi: 10.1093/nar/gky596.


Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages.

Recio C, Lucy D, Purvis GSD, Iveson P, Zeboudj L, Iqbal AJ, Lin D, O'Callaghan C, Davison L, Griesbach E, Russell AJ, Wynne GM, Dib L, Monaco C, Greaves DR.

Front Immunol. 2018 Jun 20;9:1419. doi: 10.3389/fimmu.2018.01419. eCollection 2018.


Ciliated conical epithelial cell protrusions point towards a diagnosis of primary ciliary dyskinesia.

O'Callaghan C, Rutman A, Williams G, Kulkarni N, Hayes J, Hirst RA.

Respir Res. 2018 Jun 25;19(1):125. doi: 10.1186/s12931-018-0782-3.


Cognitive training for freezing of gait in Parkinson's disease: a randomized controlled trial.

Walton CC, Mowszowski L, Gilat M, Hall JM, O'Callaghan C, Muller AJ, Georgiades M, Szeto JYY, Ehgoetz Martens KA, Shine JM, Naismith SL, Lewis SJG.

NPJ Parkinsons Dis. 2018 May 18;4:15. doi: 10.1038/s41531-018-0052-6. eCollection 2018.


Does implementation matter if comprehension is lacking? A qualitative investigation into perceptions of advance care planning in people with cancer.

Ugalde A, O'Callaghan C, Byard C, Brean S, MacKay J, Boltong A, Davoren S, Lawson D, Parente P, Michael N, Livingston P.

Support Care Cancer. 2018 Nov;26(11):3765-3771. doi: 10.1007/s00520-018-4241-y. Epub 2018 May 11.


Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.

Tagalakis AD, Munye MM, Ivanova R, Chen H, Smith CM, Aldossary AM, Rosa LZ, Moulding D, Barnes JL, Kafetzis KN, Jones SA, Baines DL, Moss GWJ, O'Callaghan C, McAnulty RJ, Hart SL.

Thorax. 2018 Sep;73(9):847-856. doi: 10.1136/thoraxjnl-2017-210670. Epub 2018 May 10.


A Website Supporting Sensitive Religious and Cultural Advance Care Planning (ACPTalk): Formative and Summative Evaluation.

Pereira-Salgado A, Mader P, O'Callaghan C, Boyd L.

JMIR Res Protoc. 2018 Apr 16;7(4):e78. doi: 10.2196/resprot.8572.


Intragenic transcriptional interference regulates the human immune ligand MICA.

Lin D, Hiron TK, O'Callaghan CA.

EMBO J. 2018 May 15;37(10). pii: e97138. doi: 10.15252/embj.201797138. Epub 2018 Apr 11.


Relationship between autonomic cardiovascular control and obstructive sleep apnoea in persons with spinal cord injury: a retrospective study.

Fang X, Goh MY, O'Callaghan C, Berlowitz D.

Spinal Cord Ser Cases. 2018 Mar 27;4:29. doi: 10.1038/s41394-018-0062-y. eCollection 2018.


Nature-based supportive care opportunities: a conceptual framework.

Blaschke S, O'Callaghan CC, Schofield P.

BMJ Support Palliat Care. 2018 Mar 22. pii: bmjspcare-2017-001465. doi: 10.1136/bmjspcare-2017-001465. [Epub ahead of print]


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