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Items: 1 to 50 of 614

1.

White matter abnormalities in retired professional rugby league players.

Wright DK, Gardner AJ, Wojtowicz M, Iverson GL, O'Brien TJ, Shultz SR, Stanwell P.

J Neurotrauma. 2020 Apr 3. doi: 10.1089/neu.2019.6886. [Epub ahead of print]

PMID:
32245344
2.

Long-term safety, efficacy, and quality of life outcomes with adjunctive brivaracetam treatment at individualized doses in patients with epilepsy: An up to 11-year, open-label, follow-up trial.

O'Brien TJ, Borghs S, He QJ, Schulz AL, Yates S, Biton V.

Epilepsia. 2020 Mar 28. doi: 10.1111/epi.16484. [Epub ahead of print]

PMID:
32221987
3.

Antiepileptic drug teratogenicity and de novo genetic variation load.

Perucca P, Anderson A, Jazayeri D, Hitchcock A, Graham J, Todaro M, Tomson T, Battino D, Perucca E, Martinez Ferri M, Rochtus A, Lagae L, Canevini MP, Zambrelli E, Campbell E, Koeleman BPC, Scheffer IE, Berkovic SF, Kwan P, Sisodiya SM, Goldstein DB, Petrovski S, Craig J, Vajda FJE, O'Brien TJ; EpiPGX and EPIGEN Consortia.

Ann Neurol. 2020 Mar 25. doi: 10.1002/ana.25724. [Epub ahead of print]

PMID:
32215971
4.

Vitamin D status in an Australian patient population: a large retrospective case series focusing on factors associated with variations in serum 25(OH)D.

Voo VTF, Stankovich J, O'Brien TJ, Butzkueven H, Monif M.

BMJ Open. 2020 Mar 4;10(3):e032567. doi: 10.1136/bmjopen-2019-032567.

5.

Immune Challenges and Seizures: How Do Early Life Insults Influence Epileptogenesis?

Semple BD, Dill LK, O'Brien TJ.

Front Pharmacol. 2020 Feb 4;11:2. doi: 10.3389/fphar.2020.00002. eCollection 2020. Review.

6.

A novel rat model of heterotopic ossification after polytrauma with traumatic brain injury.

Brady RD, Zhao MZ, Wong KR, Casilla-Espinosa PM, Yamakawa GR, Wortman RC, Sun M, Grills BL, Mychasiuk R, O'Brien TJ, Agoston DV, Lee PVS, McDonald SJ, Robinson DL, Shultz SR.

Bone. 2020 Apr;133:115263. doi: 10.1016/j.bone.2020.115263. Epub 2020 Feb 4.

PMID:
32032779
7.

Antiepileptic drugs are not independently associated with cognitive dysfunction.

Foster E, Malpas CB, Ye K, Johnstone B, Carney PW, Velakoulis D, O'Brien TJ, Kwan P.

Neurology. 2020 Mar 10;94(10):e1051-e1061. doi: 10.1212/WNL.0000000000009061. Epub 2020 Feb 3.

PMID:
32015172
8.

A Simple and Reliable Protocol for the Preparation and Culturing of Fresh Surgically Resected Human Glioblastoma Tissue.

Kan LK, Drummond KJ, Hunn M, Williams DA, O'Brien TJ, Monif M.

Methods Protoc. 2020 Jan 22;3(1). pii: E11. doi: 10.3390/mps3010011.

9.

High-Frequency Irreversible Electroporation for Treatment of Primary Liver Cancer: A Proof-of-Principle Study in Canine Hepatocellular Carcinoma.

Partridge BR, O'Brien TJ, Lorenzo MF, Coutermarsh-Ott SL, Barry SL, Stadler K, Muro N, Meyerhoeffer M, Allen IC, Davalos RV, Dervisis NG.

J Vasc Interv Radiol. 2020 Mar;31(3):482-491.e4. doi: 10.1016/j.jvir.2019.10.015. Epub 2020 Jan 16.

PMID:
31956003
10.

Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity.

Therajaran P, Hamilton JA, O'Brien TJ, Jones NC, Ali I.

Epilepsia. 2020 Feb;61(2):203-215. doi: 10.1111/epi.16424. Epub 2020 Jan 13. Review.

PMID:
31943156
11.

The need to incorporate aged animals into the preclinical modeling of neurological conditions.

Sun M, McDonald SJ, Brady RD, Collins-Praino L, Yamakawa GR, Monif M, O'Brien TJ, Cloud GC, Sobey CG, Mychasiuk R, Loane DJ, Shultz SR.

Neurosci Biobehav Rev. 2020 Feb;109:114-128. doi: 10.1016/j.neubiorev.2019.12.027. Epub 2019 Dec 23. Review.

PMID:
31877345
12.

A Continuous-Flow Model for in vitro Cultivation of Mixed Microbial Populations Associated With Cystic Fibrosis Airway Infections.

O'Brien TJ, Welch M.

Front Microbiol. 2019 Nov 22;10:2713. doi: 10.3389/fmicb.2019.02713. eCollection 2019.

13.

Genomic and clinical predictors of lacosamide response in refractory epilepsies.

Heavin SB, McCormack M, Wolking S, Slattery L, Walley N, Avbersek A, Novy J, Sinha SR, Radtke R, Doherty C, Auce P, Craig J, Johnson MR, Koeleman BPC, Krause R, Kunz WS, Marson AG, O'Brien TJ, Sander JW, Sills GJ, Stefansson H, Striano P, Zara F; EPIGEN Consortium; EpiPGX Consortium, Depondt C, Sisodiya S, Goldstein D, Lerche H, Cavalleri GL, Delanty N.

Epilepsia Open. 2019 Sep 25;4(4):563-571. doi: 10.1002/epi4.12360. eCollection 2019 Dec.

14.

Role of cerebral glutamate in post-stroke epileptogenesis.

Nicolo JP, O'Brien TJ, Kwan P.

Neuroimage Clin. 2019;24:102069. doi: 10.1016/j.nicl.2019.102069. Epub 2019 Nov 5. Review.

15.

NMDA receptors on parvalbumin-positive interneurons and pyramidal neurons both contribute to MK-801 induced gamma oscillatory disturbances: Complex relationships with behaviour.

Hudson MR, Sokolenko E, O'Brien TJ, Jones NC.

Neurobiol Dis. 2020 Feb;134:104625. doi: 10.1016/j.nbd.2019.104625. Epub 2019 Nov 28.

16.

Comparisons of direct and indirect utilities in adult epilepsy populations: A systematic review.

Foster E, Chen Z, Ofori-Asenso R, Norman R, Carney P, O'Brien TJ, Kwan P, Liew D, Ademi Z.

Epilepsia. 2019 Dec;60(12):2466-2476. doi: 10.1111/epi.16396. Epub 2019 Nov 30.

PMID:
31784994
17.

Recapitulation of polymicrobial communities associated with cystic fibrosis airway infections: a perspective.

O'Brien TJ, Welch M.

Future Microbiol. 2019 Nov;14:1437-1450. doi: 10.2217/fmb-2019-0200. Epub 2019 Nov 28.

PMID:
31778075
18.

Bone Health in Rats With Temporal Lobe Epilepsy in the Absence of Anti-Epileptic Drugs.

Brady RD, Wong KR, Robinson DL, Mychasiuk R, McDonald SJ, D'Cunha RA, Yamakawa GR, Sun M, Wark JD, Lee PVS, O'Brien TJ, Casillas-Espinosa PM, Shultz SR.

Front Pharmacol. 2019 Oct 29;10:1278. doi: 10.3389/fphar.2019.01278. eCollection 2019.

19.

Neuroinflammation in Post-Traumatic Epilepsy: Pathophysiology and Tractable Therapeutic Targets.

Sharma R, Leung WL, Zamani A, O'Brien TJ, Casillas Espinosa PM, Semple BD.

Brain Sci. 2019 Nov 9;9(11). pii: E318. doi: 10.3390/brainsci9110318. Review.

20.

Preexisting illness, fetal malformation, and seizure control rates in pregnant women with epilepsy.

Vajda FJE, O'Brien TJ, Graham JE, Hitchcock AA, Lander CM, Eadie MJ.

Epilepsy Behav. 2020 Feb;103(Pt A):106481. doi: 10.1016/j.yebeh.2019.106481. Epub 2019 Nov 9.

PMID:
31711866
21.

Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures.

Wang AD, Leong M, Johnstone B, Rayner G, Kalincik T, Roos I, Kwan P, O'Brien TJ, Velakoulis D, Malpas CB.

Epilepsy Res. 2019 Dec;158:106234. doi: 10.1016/j.eplepsyres.2019.106234. Epub 2019 Nov 1.

PMID:
31706137
22.

Author response: Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring.

Sivathamboo S, O'Brien TJ, Goldin J, Perucca P, Kwan P, Velakoulis D.

Neurology. 2019 Nov 5;93(19):864-865. doi: 10.1212/WNL.0000000000008454. No abstract available.

PMID:
31685711
23.

The effects of cell therapy on seizures in animal models of epilepsy: protocol for systematic review and meta-analysis of preclinical studies.

Dvir N, Javaid MS, Jones NC, Powell KL, Kwan P, O'Brien TJ, Antonic-Baker A.

Syst Rev. 2019 Nov 1;8(1):255. doi: 10.1186/s13643-019-1169-3.

24.

Abbreviated assessment of psychopathology in patients with suspected seizure disorders.

Malpas CB, Wang AD, Leong M, Johnstone B, Rayner G, Kalincik T, Kwan P, O'Brien TJ, Velakoulis D.

Epilepsy Behav. 2019 Nov;100(Pt A):106530. doi: 10.1016/j.yebeh.2019.106530. Epub 2019 Oct 25.

PMID:
31665694
25.

Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures.

Leong M, Wang AD, Trainor D, Johnstone B, Rayner G, Kalincik T, Roos I, Kwan P, O'Brien TJ, Velakoulis D, Malpas CB.

Seizure. 2019 Dec;73:1-8. doi: 10.1016/j.seizure.2019.10.011. Epub 2019 Oct 17.

PMID:
31655442
26.

Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat.

Wright DK, Brady RD, Kamnaksh A, Trezise J, Sun M, McDonald SJ, Mychasiuk R, Kolbe SC, Law M, Johnston LA, O'Brien TJ, Agoston DV, Shultz SR.

Sci Rep. 2019 Oct 10;9(1):14626. doi: 10.1038/s41598-019-51267-w.

27.

Innate Immunity in the Central Nervous System: A Missing Piece of the Autoimmune Encephalitis Puzzle?

Wesselingh R, Butzkueven H, Buzzard K, Tarlinton D, O'Brien TJ, Monif M.

Front Immunol. 2019 Sep 10;10:2066. doi: 10.3389/fimmu.2019.02066. eCollection 2019. Review.

28.

Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy.

O'Brien TJ, Lorenzo MF, Zhao Y, Neal Ii RE, Robertson JL, Goldberg SN, Davalos RV.

Int J Hyperthermia. 2019;36(1):953-963. doi: 10.1080/02656736.2019.1657187.

PMID:
31542973
29.

Seizures in infancy in the offspring of women with epilepsy.

Vajda FJE, O'Brien TJ, Graham JE, Hitchcock AA, Lander CM, Eadie MJ.

Acta Neurol Scand. 2020 Jan;141(1):33-37. doi: 10.1111/ane.13170. Epub 2019 Oct 22.

PMID:
31532859
30.

Tau Related Pathways as a Connecting Link between Epilepsy and Alzheimer's Disease.

Paudel YN, Angelopoulou E, Jones NC, O'Brien TJ, Kwan P, Piperi C, Othman I, Shaikh MF.

ACS Chem Neurosci. 2019 Oct 16;10(10):4199-4212. doi: 10.1021/acschemneuro.9b00460. Epub 2019 Sep 30.

PMID:
31532186
31.

The genetic ablation of tau improves long-term, but not short-term, functional outcomes after experimental traumatic brain injury in mice.

Tan XL, Zheng P, Wright DK, Sun M, Brady RD, Liu S, McDonald SJ, Mychasiuk R, Cenap S, Jones NC, O'Brien TJ, Shultz SR.

Brain Inj. 2020;34(1):131-139. doi: 10.1080/02699052.2019.1667539. Epub 2019 Sep 16.

PMID:
31526028
32.

An animal model of genetic predisposition to develop acquired epileptogenesis: The FAST and SLOW rats.

Leung WL, Casillas-Espinosa P, Sharma P, Perucca P, Powell K, O'Brien TJ, Semple BD.

Epilepsia. 2019 Oct;60(10):2023-2036. doi: 10.1111/epi.16329. Epub 2019 Aug 29. Review.

PMID:
31468516
33.

Comparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy.

Silvennoinen K, de Lange N, Zagaglia S, Balestrini S, Androsova G, Wassenaar M, Auce P, Avbersek A, Becker F, Berghuis B, Campbell E, Coppola A, Francis B, Wolking S, Cavalleri GL, Craig J, Delanty N, Johnson MR, Koeleman BPC, Kunz WS, Lerche H, Marson AG, O'Brien TJ, Sander JW, Sills GJ, Striano P, Zara F, van der Palen J, Krause R, Depondt C, Sisodiya SM; EpiPGX Consortium.

Epilepsia Open. 2019 Jul 4;4(3):420-430. doi: 10.1002/epi4.12349. eCollection 2019 Sep.

34.

Disease-modifying effects of a novel T-type calcium channel antagonist, Z944, in a model of temporal lobe epilepsy.

Casillas-Espinosa PM, Shultz SR, Braine EL, Jones NC, Snutch TP, Powell KL, O'Brien TJ.

Prog Neurobiol. 2019 Nov;182:101677. doi: 10.1016/j.pneurobio.2019.101677. Epub 2019 Aug 13.

PMID:
31419467
35.

Epilepsy and seizure-related deaths: Mortality statistics do not tell the complete story.

Panelli RJ, O'Brien TJ.

Epilepsy Behav. 2019 Sep;98(Pt A):266-272. doi: 10.1016/j.yebeh.2019.07.003. Epub 2019 Aug 10.

PMID:
31408827
36.

Acquired cardiac channelopathies in epilepsy: Evidence, mechanisms, and clinical significance.

Li MCH, O'Brien TJ, Todaro M, Powell KL.

Epilepsia. 2019 Sep;60(9):1753-1767. doi: 10.1111/epi.16301. Epub 2019 Jul 29. Review.

PMID:
31353444
37.

Pharmaceutical Benefits Scheme restrictions on anti-epileptic drug prescribing promote unsafe and outdated practice.

Gericke CA, O'Brien TJ.

Med J Aust. 2019 Jul;211(2):55-57.e1. doi: 10.5694/mja2.50246. Epub 2019 Jun 30. No abstract available.

PMID:
31256431
38.

Multiunit cluster firing patterns of piriform cortex and mediodorsal thalamus in absence epilepsy.

Young JC, Nasser HM, Casillas-Espinosa PM, O'Brien TJ, Jackson GD, Paolini AG.

Epilepsy Behav. 2019 Aug;97:229-243. doi: 10.1016/j.yebeh.2019.05.032. Epub 2019 Jun 26.

PMID:
31254843
39.

Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury: Chronic neuroinflammatory, behavioral, and epileptogenic consequences.

Webster KM, Shultz SR, Ozturk E, Dill LK, Sun M, Casillas-Espinosa P, Jones NC, Crack PJ, O'Brien TJ, Semple BD.

Exp Neurol. 2019 Oct;320:112979. doi: 10.1016/j.expneurol.2019.112979. Epub 2019 Jun 21.

PMID:
31229637
40.

Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences.

Scheltema MJ, O'Brien TJ, van den Bos W, de Bruin DM, Davalos RV, van den Geld CWM, Laguna MP, Neal RE 2nd, Varkarakis IM, Skolarikos A, Stricker PD, de Reijke TM, Arena CB, de la Rosette J.

Ther Adv Urol. 2019 Jun 7;11:1756287219852305. doi: 10.1177/1756287219852305. eCollection 2019 Jan-Dec.

41.

Cav 3.2 T-type calcium channel mutation influences kindling-induced thalamic neuronal firing patterns in Genetic Absence Epilepsy Rats From Strasbourg.

Çarçak N, Ali I, Powell K, Zheng T, Onat F, O'Brien TJ.

Epilepsia. 2019 Jul;60(7):1378-1386. doi: 10.1111/epi.16076. Epub 2019 Jun 17.

PMID:
31206645
42.

The utility of an automated and ambulatory device for detecting and differentiating epileptic and psychogenic non-epileptic seizures.

Naganur VD, Kusmakar S, Chen Z, Palaniswami MS, Kwan P, O'Brien TJ.

Epilepsia Open. 2019 May 13;4(2):309-317. doi: 10.1002/epi4.12327. eCollection 2019 Jun.

43.

Experimental High-Frequency Irreversible Electroporation Using a Single-Needle Delivery Approach for Nonthermal Pancreatic Ablation In Vivo.

O'Brien TJ, Passeri M, Lorenzo MF, Sulzer JK, Lyman WB, Swet JH, Vrochides D, Baker EH, Iannitti DA, Davalos RV, McKillop IH.

J Vasc Interv Radiol. 2019 Jun;30(6):854-862.e7. doi: 10.1016/j.jvir.2019.01.032.

PMID:
31126597
44.

Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis.

Casillas-Espinosa PM, Andrade P, Santana-Gomez C, Paananen T, Smith G, Ali I, Ciszek R, Ndode-Ekane XE, Brady RD, Tohka J, Hudson MR, Perucca P, Braine EL, Immonen R, Puhakka N, Shultz SR, Jones NC, Staba RJ, Pitkänen A, O'Brien TJ.

Epilepsy Res. 2019 Oct;156:106131. doi: 10.1016/j.eplepsyres.2019.04.011. Epub 2019 Apr 27.

PMID:
31076256
45.

Aged rats have an altered immune response and worse outcomes after traumatic brain injury.

Sun M, Brady RD, Casillas-Espinosa PM, Wright DK, Semple BD, Kim HA, Mychasiuk R, Sobey CG, O'Brien TJ, Vinh A, McDonald SJ, Shultz SR.

Brain Behav Immun. 2019 Aug;80:536-550. doi: 10.1016/j.bbi.2019.04.038. Epub 2019 Apr 27.

PMID:
31039431
46.

Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems.

Sharma R, Shultz SR, Robinson MJ, Belli A, Hibbs ML, O'Brien TJ, Semple BD.

Brain Behav Immun. 2019 Jul;79:63-74. doi: 10.1016/j.bbi.2019.04.034. Epub 2019 Apr 25. Review.

PMID:
31029794
47.

Focal stimulation of the sheep motor cortex with a chronically implanted minimally invasive electrode array mounted on an endovascular stent.

Opie NL, John SE, Rind GS, Ronayne SM, Wong YT, Gerboni G, Yoo PE, Lovell TJH, Scordas TCM, Wilson SL, Dornom A, Vale T, O'Brien TJ, Grayden DB, May CN, Oxley TJ.

Nat Biomed Eng. 2018 Dec;2(12):907-914. doi: 10.1038/s41551-018-0321-z. Epub 2018 Dec 3.

PMID:
31015727
48.

Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis.

Santana-Gomez C, Andrade P, Hudson MR, Paananen T, Ciszek R, Smith G, Ali I, Rundle BK, Ndode-Ekane XE, Casillas-Espinosa PM, Immonen R, Puhakka N, Jones N, Brady RD, Perucca P, Shultz SR, Pitkänen A, O'Brien TJ, Staba R.

Epilepsy Res. 2019 Oct;156:106110. doi: 10.1016/j.eplepsyres.2019.03.008. Epub 2019 Mar 15.

PMID:
30981541
49.

Targeting Glioma Stem Cells by Functional Inhibition of Dynamin 2: A Novel Treatment Strategy for Glioblastoma.

Luwor R, Morokoff AP, Amiridis S, D'Abaco G, Paradiso L, Stylli SS, Nguyen HPT, Tarleton M, Young KA, O'Brien TJ, Robinson PJ, Chircop M, McCluskey A, Jones NC.

Cancer Invest. 2019;37(3):144-155. doi: 10.1080/07357907.2019.1582060. Epub 2019 Mar 25.

PMID:
30907150
50.

Randomized trial of add-on triheptanoin vs medium chain triglycerides in adults with refractory epilepsy.

Borges K, Kaul N, Germaine J, Kwan P, O'Brien TJ.

Epilepsia Open. 2019 Feb 22;4(1):153-163. doi: 10.1002/epi4.12308. eCollection 2019 Mar.

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