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Derivation of two iPSC lines from a sporadic ASD patient (NUIGi033-A) and a paternal control (NUIGi034-A).

de la Cruz BM, Ding Y, McInerney V, Krawczyk J, Lu Y, Yang G, Qian X, Li W, Howard L, Allen NM, O'Brien T, Gallagher L, Shen S.

Stem Cell Res. 2020 Feb 4;44:101722. doi: 10.1016/j.scr.2020.101722. [Epub ahead of print]


"Balancing Expectations with Actual Realities": Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial.

McGill BC, Wakefield CE, Hetherington K, Munro LJ, Warby M, Lau L, Tyrrell V, Ziegler DS, O'Brien TA, Marshall GM, Malkin D, Hansford JR, Tucker KM, Vetsch J.

J Pers Med. 2020 Feb 14;10(1). pii: E9. doi: 10.3390/jpm10010009.


A novel rat model of heterotopic ossification after polytrauma with traumatic brain injury.

Brady RD, Zhao MZ, Wong KR, Casilla-Espinosa PM, Yamakawa GR, Wortman RC, Sun M, Grills BL, Mychasiuk R, O'Brien TJ, Agoston DV, Lee PVS, McDonald SJ, Robinson DL, Shultz SR.

Bone. 2020 Apr;133:115263. doi: 10.1016/j.bone.2020.115263. Epub 2020 Feb 4.


Knowledge, Perceptions and Concerns of Diabetes -Associated Complications Among Individuals Living with Type 1 and Type 2 Diabetes Mellitus.

Sanz-Nogués C, Mustafa M, Burke H, O'Brien T, Coleman CM.

Healthcare (Basel). 2020 Jan 30;8(1). pii: E25. doi: 10.3390/healthcare8010025.


Antiepileptic drugs are not independently associated with cognitive dysfunction.

Foster E, Malpas CB, Ye K, Johnstone B, Carney PW, Velakoulis D, O'Brien TJ, Kwan P.

Neurology. 2020 Feb 3. pii: 10.1212/WNL.0000000000009061. doi: 10.1212/WNL.0000000000009061. [Epub ahead of print]


Childhood cancer: unique opportunities and inherent challenges.

Manoharan N, O'Brien T.

Med J Aust. 2020 Feb;212(3):110-111. doi: 10.5694/mja2.50487. Epub 2020 Jan 25. No abstract available.


Stair negotiation behaviour of older individuals: Do step dimensions matter?

Ackermans TMA, Francksen NC, Casana-Eslava RV, Lees C, Baltzopoulos V, Lisboa PJG, Hollands MA, O'Brien TD, Maganaris CN.

J Biomech. 2020 Mar 5;101:109616. doi: 10.1016/j.jbiomech.2020.109616. Epub 2020 Jan 9.


A Simple and Reliable Protocol for the Preparation and Culturing of Fresh Surgically Resected Human Glioblastoma Tissue.

Kan LK, Drummond KJ, Hunn M, Williams DA, O'Brien TJ, Monif M.

Methods Protoc. 2020 Jan 22;3(1). pii: E11. doi: 10.3390/mps3010011.


Recent Decline in Hepatocellular Carcinoma Rates in the United States.

Shiels MS, O'Brien TR.

Gastroenterology. 2020 Jan 18. pii: S0016-5085(20)30010-X. doi: 10.1053/j.gastro.2019.12.030. [Epub ahead of print] No abstract available.


Optimal lighting levels for stair safety: Influence of lightbulb type and brightness on confidence, dynamic balance and stepping characteristics.

Thomas NM, Skervin T, Foster RJ, O'Brien TD, Carpenter MG, Maganaris CN, Baltzopoulos V, Lees C, Hollands MA.

Exp Gerontol. 2020 Apr;132:110839. doi: 10.1016/j.exger.2020.110839. Epub 2020 Jan 17.


High-Frequency Irreversible Electroporation for Treatment of Primary Liver Cancer: A Proof-of-Principle Study in Canine Hepatocellular Carcinoma.

Partridge BR, O'Brien TJ, Lorenzo MF, Coutermarsh-Ott SL, Barry SL, Stadler K, Muro N, Meyerhoeffer M, Allen IC, Davalos RV, Dervisis NG.

J Vasc Interv Radiol. 2020 Mar;31(3):482-491.e4. doi: 10.1016/j.jvir.2019.10.015. Epub 2020 Jan 16.


Derivation of familial iPSC lines from three patients with retinitis pigmentosa carrying an autosomal dominant RPE65 mutation (NUIGi027-A, NUIGi028-A, NUIGi029-A).

Ding Y, Carvalho E, Murphy C, McInerney V, Krawczyk J, O'Brien T, Howard L, Cai L, Shen S.

Stem Cell Res. 2019 Nov 28;43:101665. doi: 10.1016/j.scr.2019.101665. [Epub ahead of print]


Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity.

Therajaran P, Hamilton JA, O'Brien TJ, Jones NC, Ali I.

Epilepsia. 2020 Feb;61(2):203-215. doi: 10.1111/epi.16424. Epub 2020 Jan 13. Review.


"TREXIT 2020": why the time to abandon transrectal prostate biopsy starts now.

Grummet J, Gorin MA, Popert R, O'Brien T, Lamb AD, Hadaschik B, Radtke JP, Wagenlehner F, Baco E, Moore CM, Emberton M, George AK, Davis JW, Szabo RJ, Buckley R, Loblaw A, Allaway M, Kastner C, Briers E, Royce PL, Frydenberg M, Murphy DG, Woo HH.

Prostate Cancer Prostatic Dis. 2020 Mar;23(1):62-65. doi: 10.1038/s41391-020-0204-8. Epub 2020 Jan 13. Review. No abstract available.


Space Radiation and Plasma Effects on Satellites and Aviation: Quantities and Metrics for Tracking Performance of Space Weather Environment Models.

Zheng Y, Ganushkina NY, Jiggens P, Jun I, Meier M, Minow JI, O'Brien TP, Pitchford D, Shprits Y, Tobiska WK, Xapsos MA, Guild TB, Mazur JE, Kuznetsova MM.

Space Weather. 2019 Oct;17(10):1384-1403. doi: 10.1029/2018SW002042. Epub 2019 Oct 15. Review.


Increased Ca2+ signaling in NRXN1α +/- neurons derived from ASD induced pluripotent stem cells.

Avazzadeh S, McDonagh K, Reilly J, Wang Y, Boomkamp SD, McInerney V, Krawczyk J, Fitzgerald J, Feerick N, O'Sullivan M, Jalali A, Forman EB, Lynch SA, Ennis S, Cosemans N, Peeters H, Dockery P, O'Brien T, Quinlan LR, Gallagher L, Shen S.

Mol Autism. 2019 Dec 30;10:52. doi: 10.1186/s13229-019-0303-3. eCollection 2019.


The need to incorporate aged animals into the preclinical modeling of neurological conditions.

Sun M, McDonald SJ, Brady RD, Collins-Praino L, Yamakawa GR, Monif M, O'Brien TJ, Cloud GC, Sobey CG, Mychasiuk R, Loane DJ, Shultz SR.

Neurosci Biobehav Rev. 2020 Feb;109:114-128. doi: 10.1016/j.neubiorev.2019.12.027. Epub 2019 Dec 23. Review.


Psychometric properties of the Hospital Anxiety and Depression Scale in an inpatient video-monitoring epilepsy cohort.

McCartney L, Johnstone B, O'Brien T, Kwan P, Kalincik T, Velakoulis D, Malpas C.

Epilepsy Behav. 2020 Feb;103(Pt A):106631. doi: 10.1016/j.yebeh.2019.106631. Epub 2019 Dec 20.


Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG-ACRIN Research Group (E5204).

Chakravarthy AB, Zhao F, Meropol NJ, Flynn PJ, Wagner LI, Sloan J, Diasio RB, Mitchell EP, Catalano P, Giantonio BJ, Catalano RB, Haller DG, Awan RA, Mulcahy MF, O'Brien TE, Santala R, Cripps C, Weis JR, Atkins JN, Leichman CG, Petrelli NJ, Sinicrope FA, Brierley JD, Tepper JE, O'Dwyer PJ, Sigurdson ER, Hamilton SR, Cella D, Benson AB 3rd.

Oncologist. 2019 Dec 18. pii: theoncologist.2019-0437. doi: 10.1634/theoncologist.2019-0437. [Epub ahead of print]


Faculty Perceptions of the Importance of Physical Assessment Skills Taught in Prelicensure Nursing Education.

Fusner SM, Moots H, OʼBrien T, Sinnott LT.

Nurse Educ. 2019 Dec 16. doi: 10.1097/NNE.0000000000000763. [Epub ahead of print]


Assessing Chemical-Induced Liver Injury In Vivo From In Vitro Gene Expression Data in the Rat: The Case of Thioacetamide Toxicity.

Schyman P, Printz RL, Estes SK, O'Brien TP, Shiota M, Wallqvist A.

Front Genet. 2019 Nov 26;10:1233. doi: 10.3389/fgene.2019.01233. eCollection 2019.


IFNL4: Notable variants and associated phenotypes.

Fang MZ, Jackson SS, O'Brien TR.

Gene. 2020 Mar 10;730:144289. doi: 10.1016/j.gene.2019.144289. Epub 2019 Dec 14. Review.


A Continuous-Flow Model for in vitro Cultivation of Mixed Microbial Populations Associated With Cystic Fibrosis Airway Infections.

O'Brien TJ, Welch M.

Front Microbiol. 2019 Nov 22;10:2713. doi: 10.3389/fmicb.2019.02713. eCollection 2019.


Genomic and clinical predictors of lacosamide response in refractory epilepsies.

Heavin SB, McCormack M, Wolking S, Slattery L, Walley N, Avbersek A, Novy J, Sinha SR, Radtke R, Doherty C, Auce P, Craig J, Johnson MR, Koeleman BPC, Krause R, Kunz WS, Marson AG, O'Brien TJ, Sander JW, Sills GJ, Stefansson H, Striano P, Zara F; EPIGEN Consortium; EpiPGX Consortium, Depondt C, Sisodiya S, Goldstein D, Lerche H, Cavalleri GL, Delanty N.

Epilepsia Open. 2019 Sep 25;4(4):563-571. doi: 10.1002/epi4.12360. eCollection 2019 Dec.


Antenatal Dads and First Year Families program: a qualitative study of fathers' and program facilitators' experiences of a community-based program in Australia.

Parry YK, Ankers MD, Abbott S, Willis L, Thorpe L, O'Brien T, Richards C.

Prim Health Care Res Dev. 2019 Dec 10;20:e154. doi: 10.1017/S1463423619000768.


Role of cerebral glutamate in post-stroke epileptogenesis.

Nicolo JP, O'Brien TJ, Kwan P.

Neuroimage Clin. 2019;24:102069. doi: 10.1016/j.nicl.2019.102069. Epub 2019 Nov 5. Review.


NMDA receptors on parvalbumin-positive interneurons and pyramidal neurons both contribute to MK-801 induced gamma oscillatory disturbances: Complex relationships with behaviour.

Hudson MR, Sokolenko E, O'Brien TJ, Jones NC.

Neurobiol Dis. 2020 Feb;134:104625. doi: 10.1016/j.nbd.2019.104625. Epub 2019 Nov 28.


Comparisons of direct and indirect utilities in adult epilepsy populations: A systematic review.

Foster E, Chen Z, Ofori-Asenso R, Norman R, Carney P, O'Brien TJ, Kwan P, Liew D, Ademi Z.

Epilepsia. 2019 Dec;60(12):2466-2476. doi: 10.1111/epi.16396. Epub 2019 Nov 30.


Recapitulation of polymicrobial communities associated with cystic fibrosis airway infections: a perspective.

O'Brien TJ, Welch M.

Future Microbiol. 2019 Nov;14:1437-1450. doi: 10.2217/fmb-2019-0200. Epub 2019 Nov 28.


Implementation of Situational Awareness in the Pediatric Oncology Setting. Does a 'huddle' Work and Is it Sustainable?

Chapman LR, Molloy L, Wright F, Oswald C, Adnum K, O'Brien TA, Mitchell R.

J Pediatr Nurs. 2020 Jan - Feb;50:75-80. doi: 10.1016/j.pedn.2019.10.016. Epub 2019 Nov 23.


Generation and characterization of twelve human induced pluripotent stem cell (iPSC) lines from four familial long QT syndrome type 1 (LQT1) patients carrying KCNQ1 c.1201dupC mutation.

Ge N, Liu M, Ding Y, Krawczyk J, McInerney V, Galvin J, Shen S, Prendiville T, O'Brien T.

Stem Cell Res. 2019 Dec;41:101650. doi: 10.1016/j.scr.2019.101650. Epub 2019 Nov 14.


Derivation of familial iPSC lines from three ASD patients carrying NRXN1α+/- and two controls (NUIGi022-A, NUIGi022-B; NUIGi023-A, NUIGi023-B; NUIGi025-A, NUIGi025-B; NUIGi024-A, NUIGi024-B; NUIGi026-A, NUIGi026-B).

Ding Y, Marcó de la Cruz B, Xia Y, Liu M, Lu Y, McInerney V, Krawczyk J, Lynch SA, Howard L, O'Brien T, Gallagher L, Shen S.

Stem Cell Res. 2019 Dec;41:101653. doi: 10.1016/j.scr.2019.101653. Epub 2019 Nov 13.


Bone Health in Rats With Temporal Lobe Epilepsy in the Absence of Anti-Epileptic Drugs.

Brady RD, Wong KR, Robinson DL, Mychasiuk R, McDonald SJ, D'Cunha RA, Yamakawa GR, Sun M, Wark JD, Lee PVS, O'Brien TJ, Casillas-Espinosa PM, Shultz SR.

Front Pharmacol. 2019 Oct 29;10:1278. doi: 10.3389/fphar.2019.01278. eCollection 2019.


Genome-Scale Model-Based Identification of Metabolite Indicators for Early Detection of Kidney Toxicity.

Pannala VR, Vinnakota KC, Estes SK, Trenary I, OˈBrien TP, Printz RL, Papin JA, Reifman J, Oyama T, Shiota M, Young JD, Wallqvist A.

Toxicol Sci. 2020 Feb 1;173(2):293-312. doi: 10.1093/toxsci/kfz228.


Neuroinflammation in Post-Traumatic Epilepsy: Pathophysiology and Tractable Therapeutic Targets.

Sharma R, Leung WL, Zamani A, O'Brien TJ, Casillas Espinosa PM, Semple BD.

Brain Sci. 2019 Nov 9;9(11). pii: E318. doi: 10.3390/brainsci9110318. Review.


Preexisting illness, fetal malformation, and seizure control rates in pregnant women with epilepsy.

Vajda FJE, O'Brien TJ, Graham JE, Hitchcock AA, Lander CM, Eadie MJ.

Epilepsy Behav. 2020 Feb;103(Pt A):106481. doi: 10.1016/j.yebeh.2019.106481. Epub 2019 Nov 9.


CCR5-Δ32 and IFNL4-ΔG/TT.

Jiang JJ, Fang MZ, Jackson SS, O'Brien TR.

Clin Ther. 2019 Dec;41(12):2658-2659. doi: 10.1016/j.clinthera.2019.10.004. Epub 2019 Nov 9. No abstract available.


Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures.

Wang AD, Leong M, Johnstone B, Rayner G, Kalincik T, Roos I, Kwan P, O'Brien TJ, Velakoulis D, Malpas CB.

Epilepsy Res. 2019 Dec;158:106234. doi: 10.1016/j.eplepsyres.2019.106234. Epub 2019 Nov 1.


What is your diagnosis? Nasal lesion in a horse with exophthalmos.

Zibura AE, Manning LK, Gwynn A, Sharkey L, de Linde Henriksen M, Coppelman E, O'Brien TD.

Vet Clin Pathol. 2019 Dec;48(4):771-773. doi: 10.1111/vcp.12790. Epub 2019 Nov 7. No abstract available.


Recruitment of Older Kidney Transplant Recipients to a Longitudinal Study.

O'Brien T, Russell CL, AlKahlout N, Rosenthal A, Meyer T, Tan A, Daloul R, Hathaway D.

Nurs Res. 2019 Nov 1. doi: 10.1097/NNR.0000000000000406. [Epub ahead of print]


Author response: Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring.

Sivathamboo S, O'Brien TJ, Goldin J, Perucca P, Kwan P, Velakoulis D.

Neurology. 2019 Nov 5;93(19):864-865. doi: 10.1212/WNL.0000000000008454. No abstract available.


The effects of cell therapy on seizures in animal models of epilepsy: protocol for systematic review and meta-analysis of preclinical studies.

Dvir N, Javaid MS, Jones NC, Powell KL, Kwan P, O'Brien TJ, Antonic-Baker A.

Syst Rev. 2019 Nov 1;8(1):255. doi: 10.1186/s13643-019-1169-3.


Abbreviated assessment of psychopathology in patients with suspected seizure disorders.

Malpas CB, Wang AD, Leong M, Johnstone B, Rayner G, Kalincik T, Kwan P, O'Brien TJ, Velakoulis D.

Epilepsy Behav. 2019 Nov;100(Pt A):106530. doi: 10.1016/j.yebeh.2019.106530. Epub 2019 Oct 25.


A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma.

Khammanivong A, Saha J, Spartz AK, Sorenson BS, Bush AG, Korpela DM, Gopalakrishnan R, Jonnalagadda S, Mereddy VR, O'Brien TD, Drewes LR, Dickerson EB.

Vet Comp Oncol. 2019 Oct 29. doi: 10.1111/vco.12551. [Epub ahead of print]


Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures.

Leong M, Wang AD, Trainor D, Johnstone B, Rayner G, Kalincik T, Roos I, Kwan P, O'Brien TJ, Velakoulis D, Malpas CB.

Seizure. 2019 Dec;73:1-8. doi: 10.1016/j.seizure.2019.10.011. Epub 2019 Oct 17.


Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma.

Lonial S, Jacobus S, Fonseca R, Weiss M, Kumar S, Orlowski RZ, Kaufman JL, Yacoub AM, Buadi FK, O'Brien T, Matous JV, Anderson DM, Emmons RV, Mahindra A, Wagner LI, Dhodapkar MV, Rajkumar SV.

J Clin Oncol. 2019 Oct 25:JCO1901740. doi: 10.1200/JCO.19.01740. [Epub ahead of print]


Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat.

Wright DK, Brady RD, Kamnaksh A, Trezise J, Sun M, McDonald SJ, Mychasiuk R, Kolbe SC, Law M, Johnston LA, O'Brien TJ, Agoston DV, Shultz SR.

Sci Rep. 2019 Oct 10;9(1):14626. doi: 10.1038/s41598-019-51267-w.


Innate Immunity in the Central Nervous System: A Missing Piece of the Autoimmune Encephalitis Puzzle?

Wesselingh R, Butzkueven H, Buzzard K, Tarlinton D, O'Brien TJ, Monif M.

Front Immunol. 2019 Sep 10;10:2066. doi: 10.3389/fimmu.2019.02066. eCollection 2019. Review.


Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy.

O'Brien TJ, Lorenzo MF, Zhao Y, Neal Ii RE, Robertson JL, Goldberg SN, Davalos RV.

Int J Hyperthermia. 2019;36(1):953-963. doi: 10.1080/02656736.2019.1657187.


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