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Metastatic Merkel-cell carcinoma: the dawn of a new era.

O'Brien T, Power DG.

BMJ Case Rep. 2018 Jul 11;2018. pii: bcr-2018-224924. doi: 10.1136/bcr-2018-224924.


Outcome of haematopoietic stem cell transplantation in dyskeratosis congenita.

Fioredda F, Iacobelli S, Korthof ET, Knol C, van Biezen A, Bresters D, Veys P, Yoshimi A, Fagioli F, Mats B, Zecca M, Faraci M, Miano M, Arcuri L, Maschan M, O'Brien T, Diaz MA, Sevilla J, Smith O, Peffault de Latour R, de la Fuente J, Or R, Van Lint MT, Tolar J, Aljurf M, Fisher A, Skorobogatova EV, Diaz de Heredia C, Risitano A, Dalle JH, Sedláček P, Ghavamzadeh A, Dufour C.

Br J Haematol. 2018 Jul 9. doi: 10.1111/bjh.15495. [Epub ahead of print]


Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats.

Masterson C, Devaney J, Horie S, O'Flynn L, Deedigan L, Elliman S, Barry F, O'Brien T, O'Toole D, Laffey JG.

Anesthesiology. 2018 Jul 5. doi: 10.1097/ALN.0000000000002327. [Epub ahead of print]


The natural history of crouch gait in bilateral cerebral palsy: A systematic review.

O'Sullivan R, Horgan F, O'Brien T, French H.

Res Dev Disabil. 2018 Jun 26;80:84-92. doi: 10.1016/j.ridd.2018.06.013. [Epub ahead of print] Review.


Neuropeptide Y affects thalamic reticular nucleus neuronal firing and network synchronization associated with suppression of spike-wave discharges.

Ali I, Gandrathi A, Zheng T, Morris MJ, O'Brien TJ, French C.

Epilepsia. 2018 Jul;59(7):1444-1454. doi: 10.1111/epi.14451. Epub 2018 Jun 20.


The impact of chronic pain-European patients' perspective over 12 months.

O'Brien T, Breivik H.

Scand J Pain. 2012 Jan 1;3(1):23-29. doi: 10.1016/j.sjpain.2011.11.004.


Diagnostic yield and accuracy of coronary CT angiography after abnormal nuclear myocardial perfusion imaging.

Meinel FG, Schoepf UJ, Townsend JC, Flowers BA, Geyer LL, Ebersberger U, Krazinski AW, Kunz WG, Thierfelder KM, Baker DW, Khan AM, Fernandes VL, O'Brien TX.

Sci Rep. 2018 Jun 15;8(1):9228. doi: 10.1038/s41598-018-27347-8.


Majorana-Based Fermionic Quantum Computation.

O'Brien TE, Rożek P, Akhmerov AR.

Phys Rev Lett. 2018 Jun 1;120(22):220504. doi: 10.1103/PhysRevLett.120.220504.


Transactive response DNA-binding protein 43 (TDP-43) abnormalities after traumatic brain injury.

Tan XL, Sun M, Brady RD, Liu SJ, Llanos R, Cheung S, Wright DK, Casillas-Espinosa PM, Sashindranath M, McDonald SJ, Turner BJ, O'Brien TJ, Shultz SR.

J Neurotrauma. 2018 Jun 14. doi: 10.1089/neu.2017.5491. [Epub ahead of print]


The phenotype of bilateral hippocampal sclerosis and its management in "real life" clinical settings.

Sen A, Dugan P, Perucca P, Costello D, Choi H, Bazil C, Radtke R, Andrade D, Depondt C, Heavin S, Adcock J, Pickrell WO, McGinty R, Nascimento F, Smith P, Rees MI, Kwan P, O'Brien TJ, Goldstein D, Delanty N.

Epilepsia. 2018 Jul;59(7):1410-1420. doi: 10.1111/epi.14436. Epub 2018 Jun 14.


Mild Traumatic Brain Injury in Adolescent Mice Alters Skull Bone Properties to Influence a Subsequent Brain Impact at Adulthood: A Pilot Study.

McColl TJ, Brady RD, Shultz SR, Lovick L, Webster KM, Sun M, McDonald SJ, O'Brien TJ, Semple BD.

Front Neurol. 2018 May 25;9:372. doi: 10.3389/fneur.2018.00372. eCollection 2018.


Development of EpiRisk: An online clinical tool for estimating the risk of major congenital malformations in pregnant women treated for epilepsy.

Davis Jones G, Hitchcock A, Vajda F, Craig J, O'Brien TJ, Sen A.

Epilepsia Open. 2018 Mar 22;3(2):281-285. doi: 10.1002/epi4.12109. eCollection 2018 Jun.


Telomere length and advanced diffusion MRI as biomarkers for repetitive mild traumatic brain injury in adolescent rats.

Wright DK, O'Brien TJ, Mychasiuk R, Shultz SR.

Neuroimage Clin. 2018 Jan 31;18:315-324. doi: 10.1016/j.nicl.2018.01.033. eCollection 2018.


Impact of IFNL4-∆G genotype on sustained virologic response in hepatitis C genotype 1 patients treated with direct-acting antivirals.

Backus LI, Shahoumian TA, Belperio PS, Winters M, Prokunina-Olsson L, O'Brien TR, Holodniy M.

Diagn Microbiol Infect Dis. 2018 Apr 14. pii: S0732-8893(18)30117-2. doi: 10.1016/j.diagmicrobio.2018.04.004. [Epub ahead of print]


Lung Cancer: One Disease or Many.

O'Brien TD, Jia P, Aldrich MC, Zhao Z.

Hum Hered. 2018 Jun 5;83(2):65-70. doi: 10.1159/000488942. [Epub ahead of print]


Rainfall From Resolved Rather Than Parameterized Processes Better Represents the Present-Day and Climate Change Response of Moderate Rates in the Community Atmosphere Model.

Kooperman GJ, Pritchard MS, O'Brien TA, Timmermans BW.

J Adv Model Earth Syst. 2018 Apr;10(4):971-988. doi: 10.1002/2017MS001188. Epub 2018 Apr 13.


PiggyBac-Engineered T Cells Expressing CD19-Specific CARs that Lack IgG1 Fc Spacers Have Potent Activity against B-ALL Xenografts.

Bishop DC, Xu N, Tse B, O'Brien TA, Gottlieb DJ, Dolnikov A, Micklethwaite KP.

Mol Ther. 2018 Jun 1. pii: S1525-0016(18)30210-7. doi: 10.1016/j.ymthe.2018.05.007. [Epub ahead of print]


Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study.

Tubi MA, Lutkenhoff E, Blanco MB, McArthur D, Villablanca P, Ellingson B, Diaz-Arrastia R, Van Ness P, Real C, Shrestha V, Engel J Jr, Vespa PM; EpiBioS4Rx Study Group Investigators, Agoston D, Au A, Bell MJ, Bleck T, Branch C, Buitrago Blanco M, Bullock R, Burrows BT, Claassen J, Clarke R, Cloyd J, Coles L, Crawford K, Diaz-Arrastia R, Duncan D, Ellingson B, Engel J, Foreman B, Galanopoulou A, Gilmore E, Olli G, Harris N, Hartings J, Lawrence H, Hunn M, Jette N, Johnston L, Jones N, Kanner A, McArthur D, Monti M, Morokoff A, Moshe S, Mowrey W, O'Brien T, O'Phelan K, Pitkanen A, Raman R, Robertson C, Rosenthal E, Shultz S, Snutch T, Staba R, Toga A, Van Horn J, Vespa P, Willyerd F, Zimmermann L.

Neurobiol Dis. 2018 Jun 1. pii: S0969-9961(18)30152-9. doi: 10.1016/j.nbd.2018.05.014. [Epub ahead of print] Review.


Chronic fluoxetine treatment accelerates kindling epileptogenesis in mice independently of 5-HT2A receptors.

Li C, Silva J, Ozturk E, Dezsi G, O'Brien TJ, Renoir T, Jones NC.

Epilepsia. 2018 Jul;59(7):e114-e119. doi: 10.1111/epi.14435. Epub 2018 Jun 1.


New-onset epilepsy in the elderly.

Vu LC, Piccenna L, Kwan P, O'Brien TJ.

Br J Clin Pharmacol. 2018 Jun 1. doi: 10.1111/bcp.13653. [Epub ahead of print] Review.


Understanding Patient Questions about their Medical Records in an Online Health Forum: Opportunity for Patient Portal Design.

Reynolds TL, Ali N, McGregor E, O'Brien T, Longhurst C, Rosenberg AL, Rudkin SE, Zheng K.

AMIA Annu Symp Proc. 2018 Apr 16;2017:1468-1477. eCollection 2017.


Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable.

John SE, Opie NL, Wong YT, Rind GS, Ronayne SM, Gerboni G, Bauquier SH, O'Brien TJ, May CN, Grayden DB, Oxley TJ.

Sci Rep. 2018 May 30;8(1):8427. doi: 10.1038/s41598-018-26457-7.


Optimized partial-coverage functional analysis pipeline (OPFAP): a semi-automated pipeline for skull stripping and co-registration of partial-coverage, ultra-high-field functional images.

Yoo PE, Cleary JO, Kolbe SC, Ordidge RJ, O'Brien TJ, Opie NL, John SE, Oxley TJ, Moffat BA.

MAGMA. 2018 May 29. doi: 10.1007/s10334-018-0690-z. [Epub ahead of print]


Comparison of pediatric allogeneic transplant outcomes using myeloablative busulfan with cyclophosphamide or fludarabine.

Harris AC, Boelens JJ, Ahn KW, Fei M, Abraham A, Artz A, Dvorak C, Frangoul H, Freytes C, Gale RP, Hong S, Lazarus HM, Loren A, Mineishi S, Nishihori T, O'Brien T, Williams K, Pasquini MC, Levine JE.

Blood Adv. 2018 Jun 12;2(11):1198-1206. doi: 10.1182/bloodadvances.2018016956.


Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer.

Drakes ML, Mehrotra S, Aldulescu M, Potkul RK, Liu Y, Grisoli A, Joyce C, O'Brien TE, Stack MS, Stiff PJ.

J Ovarian Res. 2018 May 30;11(1):43. doi: 10.1186/s13048-018-0414-z.


Effects of internal electrode cooling on irreversible electroporation using a perfused organ model.

O'Brien TJ, Bonakdar M, Bhonsle S, Neal RE 2nd, Aardema CH Jr, Robertson JL, Goldberg SN, Davalos RV.

Int J Hyperthermia. 2018 May 28:1-12. doi: 10.1080/02656736.2018.1473893. [Epub ahead of print]


Hepatitis D Viremia Among Injection Drug Users in San Francisco.

Mahale P, Aka PV, Chen X, Liu P, Fram BJ, Wang AS, Simenel S, Tseng FC, Chen S, Edlin BR, Glenn JS, O'Brien TR.

J Infect Dis. 2018 May 25;217(12):1902-1906. doi: 10.1093/infdis/jiy157.


Antiepileptic drug polytherapy in pregnant women with epilepsy.

Vajda FJE, O'Brien TJ, Graham JE, Hitchcock AA, Lander CM, Eadie MJ.

Acta Neurol Scand. 2018 Aug;138(2):115-121. doi: 10.1111/ane.12965. Epub 2018 May 24.


Pathways to Recovery: development and evaluation of a cognitive-behavioural therapy in-patient treatment programme for adults with anorexia nervosa.

Brown A, Jenkinson R, Coakes J, Cockfield A, O'Brien T, Hall L.

BJPsych Bull. 2018 Jun;42(3):95-101. doi: 10.1192/bjb.2017.30.


Multiplex Polymerase Chain Reaction Assay for Screening of Mycotoxin Genes From Ocular Isolates of Fusarium species.

Anutarapongpan O, Maestre-Mesa J, Alfonso EC, OʼBrien TP, Miller D.

Cornea. 2018 Aug;37(8):1042-1046. doi: 10.1097/ICO.0000000000001607.


The Development of Delta: Using Agile to Develop a Decision Aid for Pediatric Oncology Clinical Trial Enrollment.

Robertson EG, Wakefield CE, Cohn RJ, O'Brien T, Ziegler DS, Fardell JE.

JMIR Res Protoc. 2018 May 4;7(5):e119. doi: 10.2196/resprot.9258.


The role of ethnicity on pregnancy outcomes in women with epilepsy: The need for specific research.

Hao N, Graham J, Hitchcock A, O'Brien TJ, Vajda FJE.

Epilepsia. 2018 Jun;59(6):1124-1131. doi: 10.1111/epi.14086. Epub 2018 May 4.



Devinsky O, Vezzani A, O'Brien TJ, Jette N, Scheffer IE, de Curtis M, Perucca P.

Nat Rev Dis Primers. 2018 May 3;4:18024. doi: 10.1038/nrdp.2018.24. Review.


Changing Face: A Key Residue for the Addition of Water by Sclareol Synthase.

Jia M, O'Brien TE, Zhang Y, Siegel JB, Tantillo DJ, Peters RJ.

ACS Catal. 2018 Apr 6;8(4):3133-3137. doi: 10.1021/acscatal.8b00121. Epub 2018 Mar 8.


Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, Nicol D, O'Brien T, Larkin J, Horswell S, Stares M, Au L, Jamal-Hanjani M, Challacombe B, Chandra A, Hazell S, Eichler-Jonsson C, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Jabbar F, Spain L, Lall S, Guarch R, Falzon M, Proctor I, Pickering L, Gore M, Watkins TBK, Ward S, Stewart A, DiNatale R, Becerra MF, Reznik E, Hsieh JJ, Richmond TA, Mayhew GF, Hill SM, McNally CD, Jones C, Rosenbaum H, Stanislaw S, Burgess DL, Alexander NR, Swanton C; PEACE; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):581-594.e12. doi: 10.1016/j.cell.2018.03.057. Epub 2018 Apr 12.


Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Horswell S, Chambers T, O'Brien T, Lopez JI, Watkins TBK, Nicol D, Stares M, Challacombe B, Hazell S, Chandra A, Mitchell TJ, Au L, Eichler-Jonsson C, Jabbar F, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Stewart A, Xing W, Smith JC, Escudero M, Huffman A, Matthews N, Elgar G, Phillimore B, Costa M, Begum S, Ward S, Salm M, Boeing S, Fisher R, Spain L, Navas C, Grönroos E, Hobor S, Sharma S, Aurangzeb I, Lall S, Polson A, Varia M, Horsfield C, Fotiadis N, Pickering L, Schwarz RF, Silva B, Herrero J, Luscombe NM, Jamal-Hanjani M, Rosenthal R, Birkbak NJ, Wilson GA, Pipek O, Ribli D, Krzystanek M, Csabai I, Szallasi Z, Gore M, McGranahan N, Van Loo P, Campbell P, Larkin J, Swanton C; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):595-610.e11. doi: 10.1016/j.cell.2018.03.043. Epub 2018 Apr 12.


Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

Mitchell TJ, Turajlic S, Rowan A, Nicol D, Farmery JHR, O'Brien T, Martincorena I, Tarpey P, Angelopoulos N, Yates LR, Butler AP, Raine K, Stewart GD, Challacombe B, Fernando A, Lopez JI, Hazell S, Chandra A, Chowdhury S, Rudman S, Soultati A, Stamp G, Fotiadis N, Pickering L, Au L, Spain L, Lynch J, Stares M, Teague J, Maura F, Wedge DC, Horswell S, Chambers T, Litchfield K, Xu H, Stewart A, Elaidi R, Oudard S, McGranahan N, Csabai I, Gore M, Futreal PA, Larkin J, Lynch AG, Szallasi Z, Swanton C, Campbell PJ; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):611-623.e17. doi: 10.1016/j.cell.2018.02.020. Epub 2018 Apr 12.


Joint moment strategies during stair descent in patients with peripheral arterial disease and intermittent claudication.

King SL, Vanicek N, O'Brien TD.

Gait Posture. 2018 May;62:359-365. doi: 10.1016/j.gaitpost.2018.03.035. Epub 2018 Mar 26.


Gender, expert advice, and judicial gatekeeping in the United States.

O'Brien TL.

Soc Sci Res. 2018 May;72:134-145. doi: 10.1016/j.ssresearch.2018.02.011. Epub 2018 Feb 26.


Management of post-traumatic epilepsy: An evidence review over the last 5 years and future directions.

Piccenna L, Shears G, O'Brien TJ.

Epilepsia Open. 2017 Mar 17;2(2):123-144. doi: 10.1002/epi4.12049. eCollection 2017 Jun.


Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Arce Vargas F, Furness AJS, Litchfield K, Joshi K, Rosenthal R, Ghorani E, Solomon I, Lesko MH, Ruef N, Roddie C, Henry JY, Spain L, Ben Aissa A, Georgiou A, Wong YNS, Smith M, Strauss D, Hayes A, Nicol D, O'Brien T, Mårtensson L, Ljungars A, Teige I, Frendéus B; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia, Pule M, Marafioti T, Gore M, Larkin J, Turajlic S, Swanton C, Peggs KS, Quezada SA.

Cancer Cell. 2018 Apr 9;33(4):649-663.e4. doi: 10.1016/j.ccell.2018.02.010. Epub 2018 Mar 22.


The feasibility of early pulmonary rehabilitation and activity after COPD exacerbations: external pilot randomised controlled trial, qualitative case study and exploratory economic evaluation.

Cox M, O'Connor C, Biggs K, Hind D, Bortolami O, Franklin M, Collins B, Walters S, Wailoo A, Channell J, Albert P, Freeman U, Bourke S, Steiner M, Miles J, O'Brien T, McWilliams D, Schofield T, O'Reilly J, Hughes R.

Health Technol Assess. 2018 Mar;22(11):1-204. doi: 10.3310/hta22110.


Spatially dynamic recurrent information flow across long-range dorsal motor network encodes selective motor goals.

Yoo PE, Hagan MA, John SE, Opie NL, Ordidge RJ, O'Brien TJ, Oxley TJ, Moffat BA, Wong YT.

Hum Brain Mapp. 2018 Jun;39(6):2635-2650. doi: 10.1002/hbm.24029. Epub 2018 Mar 8.


The Effects of Closed-Loop Brain Implants on Autonomy and Deliberation: What are the Risks of Being Kept in the Loop?

Gilbert F, O'Brien T, Cook M.

Camb Q Healthc Ethics. 2018 Apr;27(2):316-325. doi: 10.1017/S0963180117000640.


Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression.

Connaughton EP, Naicker S, Hanley SA, Slevin SM, Eykelenboom JK, Lowndes NF, O'Brien T, Ceredig R, Griffin MD, Dennedy MC.

Immunol Cell Biol. 2018 Mar 5. doi: 10.1111/imcb.12032. [Epub ahead of print]


A 3-month Safety Assessment of Human Bone Marrow Derived Mesenchymal Stromal Cells Administered Once by the Intramuscular Route to Immunodeficient Mice.

Creane M, McElroy M, Duffy A, Dawood CS, O'Brien T.

Toxicol Pathol. 2018 Apr;46(3):290-301. doi: 10.1177/0192623318760516. Epub 2018 Mar 4.


Weak sharing of genetic association signals in three lung cancer subtypes: evidence at the SNP, gene, regulation, and pathway levels.

O'Brien TD, Jia P, Caporaso NE, Landi MT, Zhao Z.

Genome Med. 2018 Feb 27;10(1):16. doi: 10.1186/s13073-018-0522-9.


The Vasoreparative Function of Myeloid Angiogenic Cells Is Impaired in Diabetes Through the Induction of IL1β.

Chambers SEJ, O'Neill CL, Guduric-Fuchs J, McLoughlin KJ, Liew A, Egan AM, O'Brien T, Stitt AW, Medina RJ.

Stem Cells. 2018 Jun;36(6):834-843. doi: 10.1002/stem.2810. Epub 2018 Mar 9.


Outcomes of pregnancies in women taking antiepileptic drugs for non-epilepsy indications.

Jazayeri D, Graham J, Hitchcock A, O'Brien TJ, Vajda FJE.

Seizure. 2018 Mar;56:111-114. doi: 10.1016/j.seizure.2018.02.009. Epub 2018 Feb 17.


CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons.

Cain SM, Tyson JR, Choi HB, Ko R, Lin PJC, LeDue JM, Powell KL, Bernier LP, Rungta RL, Yang Y, Cullis PR, O'Brien TJ, MacVicar BA, Snutch TP.

Epilepsia. 2018 Apr;59(4):778-791. doi: 10.1111/epi.14018. Epub 2018 Feb 21.

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