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Items: 1 to 50 of 142


Evaluating Skilled Prehension in Mice Using an Auto-Trainer.

Hubbard R, Dunthorn J, O'Brien RJ, Tasch D, Tasch U, Zeiler SR.

J Vis Exp. 2019 Sep 12;(151). doi: 10.3791/59784.


Magnetic resonance imaging of mouse brain networks plasticity following motor learning.

Badea A, Ng KL, Anderson RJ, Zhang J, Miller MI, O'Brien RJ.

PLoS One. 2019 May 8;14(5):e0216596. doi: 10.1371/journal.pone.0216596. eCollection 2019.


Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children.

Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J, Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL.

Clin Infect Dis. 2017 Jan 15;64(2):111-115. doi: 10.1093/cid/ciw778.


Long-term cortisol measures predict Alzheimer disease risk.

Ennis GE, An Y, Resnick SM, Ferrucci L, O'Brien RJ, Moffat SD.

Neurology. 2017 Jan 24;88(4):371-378. doi: 10.1212/WNL.0000000000003537. Epub 2016 Dec 16.


Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children.

Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J, Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL.

Clin Infect Dis. 2017 Jan 15;64(2):e1-e33. doi: 10.1093/cid/ciw694. Epub 2016 Dec 8.


Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.

Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, Troncoso JC, Albert MS, Thambisetty M.

Mol Psychiatry. 2017 Jan;22(1):13-23. doi: 10.1038/mp.2016.206. Epub 2016 Nov 22.


Hypothetical Preclinical Alzheimer Disease Groups and Longitudinal Cognitive Change.

Soldan A, Pettigrew C, Cai Q, Wang MC, Moghekar AR, O'Brien RJ, Selnes OA, Albert MS; BIOCARD Research Team.

JAMA Neurol. 2016 Jun 1;73(6):698-705. doi: 10.1001/jamaneurol.2016.0194.


Midlife adiposity predicts earlier onset of Alzheimer's dementia, neuropathology and presymptomatic cerebral amyloid accumulation.

Chuang YF, An Y, Bilgel M, Wong DF, Troncoso JC, O'Brien RJ, Breitner JC, Ferruci L, Resnick SM, Thambisetty M.

Mol Psychiatry. 2016 Jul;21(7):910-5. doi: 10.1038/mp.2015.129. Epub 2015 Sep 1.


Fluoxetine Maintains a State of Heightened Responsiveness to Motor Training Early After Stroke in a Mouse Model.

Ng KL, Gibson EM, Hubbard R, Yang J, Caffo B, O'Brien RJ, Krakauer JW, Zeiler SR.

Stroke. 2015 Oct;46(10):2951-60. doi: 10.1161/STROKEAHA.115.010471. Epub 2015 Aug 20.


Changes in Aβ biomarkers and associations with APOE genotype in 2 longitudinal cohorts.

Resnick SM, Bilgel M, Moghekar A, An Y, Cai Q, Wang MC, Thambisetty M, Prince JL, Zhou Y, Soldan A, Wong DF, O'Brien RJ, Ferrucci L, Albert MS.

Neurobiol Aging. 2015 Aug;36(8):2333-9. doi: 10.1016/j.neurobiolaging.2015.04.001. Epub 2015 Apr 4.


FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder.

Guancial EA, Werner L, Bellmunt J, Bamias A, Choueiri TK, Ross R, Schutz FA, Park RS, O'Brien RJ, Hirsch MS, Barletta JA, Berman DM, Lis R, Loda M, Stack EC, Garraway LA, Riester M, Michor F, Kantoff PW, Rosenberg JE.

Cancer Med. 2014 Aug;3(4):835-44. doi: 10.1002/cam4.262. Epub 2014 May 21.


Changes in brain function occur years before the onset of cognitive impairment.

Beason-Held LL, Goh JO, An Y, Kraut MA, O'Brien RJ, Ferrucci L, Resnick SM.

J Neurosci. 2013 Nov 13;33(46):18008-14. doi: 10.1523/JNEUROSCI.1402-13.2013.


Cost-effectiveness comparison of Genechip and conventional drug susceptibility test for detecting multidrug-resistant tuberculosis in China.

Pang Y, Li Q, Ou X, Sohn H, Zhang Z, Li J, Xia H, Kam KM, O'Brien RJ, Chi J, Huan S, Chin DP, Zhao YL.

PLoS One. 2013 Jul 23;8(7):e69267. doi: 10.1371/journal.pone.0069267. Print 2013.


Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging.

Thambisetty M, Jeffrey Metter E, Yang A, Dolan H, Marano C, Zonderman AB, Troncoso JC, Zhou Y, Wong DF, Ferrucci L, Egan J, Resnick SM, O'Brien RJ.

JAMA Neurol. 2013 Sep 1;70(9):1167-72.


Personality and risk of Alzheimer's disease: new data and meta-analysis.

Terracciano A, Sutin AR, An Y, O'Brien RJ, Ferrucci L, Zonderman AB, Resnick SM.

Alzheimers Dement. 2014 Mar;10(2):179-86. doi: 10.1016/j.jalz.2013.03.002. Epub 2013 May 21.


The changing landscape of diagnostic services for tuberculosis.

Boehme CC, Saacks S, O'Brien RJ.

Semin Respir Crit Care Med. 2013 Feb;34(1):17-31. doi: 10.1055/s-0032-1333468. Epub 2013 Mar 4. Review.


Medial premotor cortex shows a reduction in inhibitory markers and mediates recovery in a mouse model of focal stroke.

Zeiler SR, Gibson EM, Hoesch RE, Li MY, Worley PF, O'Brien RJ, Krakauer JW.

Stroke. 2013 Feb;44(2):483-9. doi: 10.1161/STROKEAHA.112.676940. Epub 2013 Jan 15. Erratum in: Stroke. 2013 Mar;44(3):e22.


Multicentre evaluation of Ziehl-Neelsen and light-emitting diode fluorescence microscopy in China.

Xia H, Song YY, Zhao B, Kam KM, O'Brien RJ, Zhang ZY, Sohn H, Wang W, Zhao YL.

Int J Tuberc Lung Dis. 2013 Jan;17(1):107-12. doi: 10.5588/ijtld.12.0184.


Carotid atherosclerosis and prospective risk of dementia.

Wendell CR, Waldstein SR, Ferrucci L, O'Brien RJ, Strait JB, Zonderman AB.

Stroke. 2012 Dec;43(12):3319-24. doi: 10.1161/STROKEAHA.112.672527. Epub 2012 Oct 25.


Cerebral white matter disease is associated with Alzheimer pathology in a prospective cohort.

Moghekar A, Kraut M, Elkins W, Troncoso J, Zonderman AB, Resnick SM, O'Brien RJ.

Alzheimers Dement. 2012 Oct;8(5 Suppl):S71-7. doi: 10.1016/j.jalz.2012.04.006.


Personality and resilience to Alzheimer's disease neuropathology: a prospective autopsy study.

Terracciano A, Iacono D, O'Brien RJ, Troncoso JC, An Y, Sutin AR, Ferrucci L, Zonderman AB, Resnick SM.

Neurobiol Aging. 2013 Apr;34(4):1045-50. doi: 10.1016/j.neurobiolaging.2012.08.008. Epub 2012 Oct 2.


Con: Alzheimer's disease and circadian dysfunction: chicken or egg?

Moghekar A, O'Brien RJ.

Alzheimers Res Ther. 2012 Aug 13;4(4):26. doi: 10.1186/alzrt129. eCollection 2012.


Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques.

Driscoll I, Troncoso JC, Rudow G, Sojkova J, Pletnikova O, Zhou Y, Kraut MA, Ferrucci L, Mathis CA, Klunk WE, O'Brien RJ, Davatzikos C, Wong DF, Resnick SM.

Acta Neuropathol. 2012 Dec;124(6):823-31. doi: 10.1007/s00401-012-1025-1. Epub 2012 Aug 5.


Longitudinal brain activity changes in asymptomatic Alzheimer disease.

Codispoti KE, Beason-Held LL, Kraut MA, O'Brien RJ, Rudow G, Pletnikova O, Crain B, Troncoso JC, Resnick SM.

Brain Behav. 2012 May;2(3):221-30. doi: 10.1002/brb3.47.


Cerebrospinal fluid Aβ and tau level fluctuation in an older clinical cohort.

Moghekar A, Goh J, Li M, Albert M, O'Brien RJ.

Arch Neurol. 2012 Feb;69(2):246-50. doi: 10.1001/archneurol.2011.732.


Amyloid precursor protein processing and Alzheimer's disease.

O'Brien RJ, Wong PC.

Annu Rev Neurosci. 2011;34:185-204. doi: 10.1146/annurev-neuro-061010-113613. Review.


Large quantities of Abeta peptide are constitutively released during amyloid precursor protein metabolism in vivo and in vitro.

Moghekar A, Rao S, Li M, Ruben D, Mammen A, Tang X, O'Brien RJ.

J Biol Chem. 2011 May 6;286(18):15989-97. doi: 10.1074/jbc.M110.191262. Epub 2011 Mar 22.


In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults.

Sojkova J, Driscoll I, Iacono D, Zhou Y, Codispoti KE, Kraut MA, Ferrucci L, Pletnikova O, Mathis CA, Klunk WE, O'Brien RJ, Wong DF, Troncoso JC, Resnick SM.

Arch Neurol. 2011 Feb;68(2):232-40. doi: 10.1001/archneurol.2010.357.


Hearing loss and incident dementia.

Lin FR, Metter EJ, O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L.

Arch Neurol. 2011 Feb;68(2):214-20. doi: 10.1001/archneurol.2010.362.


Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment.

Okonkwo OC, Mielke MM, Griffith HR, Moghekar AR, O'Brien RJ, Shaw LM, Trojanowski JQ, Albert MS; Alzheimer's Disease Neuroimaging Initiative.

Arch Neurol. 2011 Jan;68(1):113-9. doi: 10.1001/archneurol.2010.334.


Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing.

Dolan D, Troncoso J, Resnick SM, Crain BJ, Zonderman AB, O'Brien RJ.

Brain. 2010 Aug;133(Pt 8):2225-31. doi: 10.1093/brain/awq141. Epub 2010 Jul 20.


Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA).

O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L, Crain BJ, Pletnikova O, Rudow G, Iacono D, Riudavets MA, Driscoll I, Price DL, Martin LJ, Troncoso JC.

J Alzheimers Dis. 2009;18(3):665-75. doi: 10.3233/JAD-2009-1179.


Effect of infarcts on dementia in the Baltimore longitudinal study of aging.

Troncoso JC, Zonderman AB, Resnick SM, Crain B, Pletnikova O, O'Brien RJ.

Ann Neurol. 2008 Aug;64(2):168-76. doi: 10.1002/ana.21413.


Trends in tuberculosis/human immunodeficiency virus comorbidity, United States, 1993-2004.

Albalak R, O'Brien RJ, Kammerer JS, O'Brien SM, Marks SM, Castro KG, Moore M.

Arch Intern Med. 2007 Dec 10;167(22):2443-52.


C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study.

Khan SQ, Dhillon OS, O'Brien RJ, Struck J, Quinn PA, Morgenthaler NG, Squire IB, Davies JE, Bergmann A, Ng LL.

Circulation. 2007 Apr 24;115(16):2103-10. Epub 2007 Apr 9.


Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) study.

Khan SQ, O'Brien RJ, Struck J, Quinn P, Morgenthaler N, Squire I, Davies J, Bergmann A, Ng LL.

J Am Coll Cardiol. 2007 Apr 10;49(14):1525-32. Epub 2007 Mar 26.


Activity dependent localization of synaptic NMDA receptors in spinal neurons.

Rosen KM, Moghekar A, O'Brien RJ.

Mol Cell Neurosci. 2007 Apr;34(4):578-91. Epub 2006 Dec 29.


Oxygen-regulated protein 150 and prognosis following myocardial infarction.

Ng LL, O'Brien RJ, Quinn PA, Squire IB, Davies JE.

Clin Sci (Lond). 2007 Jul;112(9):477-84.


Safe use of brain natriuretic protein to rule out the diagnosis of heart failure depends on the selection of cut off value.

Williams SG, Ng LL, O'Brien RJ, Barker D, Li YF, Tan LB.

Heart. 2005 Aug;91(8):1090-1. No abstract available.


Complementary roles of simple variables, NYHA and N-BNP, in indicating aerobic capacity and severity of heart failure.

Williams SG, Ng LL, O'Brien RJ, Taylor S, Wright DJ, Li YF, Tan LB.

Int J Cardiol. 2005 Jul 10;102(2):279-86.


New drugs for tuberculosis: current status and future prospects.

O'Brien RJ, Spigelman M.

Clin Chest Med. 2005 Jun;26(2):327-40, vii. Review.


Brief screening tests for the diagnosis of dementia: comparison with the mini-mental state exam.

Kilada S, Gamaldo A, Grant EA, Moghekar A, Morris JC, O'Brien RJ.

Alzheimer Dis Assoc Disord. 2005 Jan-Mar;19(1):8-16.


Is plasma N-BNP a good indicator of the functional reserve of failing hearts? The FRESH-BNP study.

Williams SG, Ng LL, O'Brien RJ, Taylor S, Wright DJ, Tan LB.

Eur J Heart Fail. 2004 Dec;6(7):891-900.


AMPA receptor-dependent clustering of synaptic NMDA receptors is mediated by Stargazin and NR2A/B in spinal neurons and hippocampal interneurons.

Mi R, Sia GM, Rosen K, Tang X, Moghekar A, Black JL, McEnery M, Huganir RL, O'Brien RJ.

Neuron. 2004 Oct 14;44(2):335-49.


Hepatotoxicity of rifampin and pyrazinamide in the treatment of latent tuberculosis infection in HIV-infected persons: is it different than in HIV-uninfected persons?

Gordin FM, Cohn DL, Matts JP, Chaisson RE, O'Brien RJ; Terry Beirn Community Programs for Clinical Research on AIDS; Adult AIDS Clinical Trials Group; Centers for Disease Control and Prevention.

Clin Infect Dis. 2004 Aug 15;39(4):561-5. Epub 2004 Jul 30.


Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis.

Nuermberger EL, Yoshimatsu T, Tyagi S, Williams K, Rosenthal I, O'Brien RJ, Vernon AA, Chaisson RE, Bishai WR, Grosset JH.

Am J Respir Crit Care Med. 2004 Nov 15;170(10):1131-4. Epub 2004 Aug 11.


Comparison of plasma N-brain natriuretic peptide, peak oxygen consumption, and left ventricular ejection fraction for severity of chronic heart failure.

Williams SG, Ng LL, O'Brien RJ, Taylor S, Li YF, Tan LB.

Am J Cardiol. 2004 Jun 15;93(12):1560-1.


LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein.

Schlickum S, Moghekar A, Simpson JC, Steglich C, O'Brien RJ, Winterpacht A, Endele SU.

Genomics. 2004 Feb;83(2):254-61.


Plasma urocortin in human systolic heart failure.

Ng LL, Loke IW, O'Brien RJ, Squire IB, Davies JE.

Clin Sci (Lond). 2004 Apr;106(4):383-8.


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