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Items: 1 to 50 of 249

1.

Reporting and ideal testosterone levels in men undergoing androgen deprivation for prostate cancer-time for a rethink?

Cabarkapa S, Perera M, Sikaris K, O'Brien JS, Bolton DM, Lawrentschuk N.

Prostate Int. 2018 Mar;6(1):1-6. doi: 10.1016/j.prnil.2017.05.003. Epub 2017 Jun 20. Review.

2.

Three dimensional models in uro-oncology: a future built with additive fabrication.

Manning TG, O'Brien JS, Christidis D, Perera M, Coles-Black J, Chuen J, Bolton DM, Lawrentschuk N.

World J Urol. 2018 Apr;36(4):557-563. doi: 10.1007/s00345-018-2201-2. Epub 2018 Jan 25. Review.

PMID:
29372352
3.

Blueprint unknown: a case for multidisciplinary management of advanced penile mycosis fungoides.

O'Brien JS, Manning T, Perera M, Prince HM, Lawrentschuk N.

Can J Urol. 2017 Dec;24(6):9139-9144.

PMID:
29260643
4.

In vitro toxicoproteomic analysis of A549 human lung epithelial cells exposed to urban air particulate matter and its water-soluble and insoluble fractions.

Vuong NQ, Breznan D, Goegan P, O'Brien JS, Williams A, Karthikeyan S, Kumarathasan P, Vincent R.

Part Fibre Toxicol. 2017 Oct 2;14(1):39. doi: 10.1186/s12989-017-0220-6.

5.

Atypical Small Acinar Proliferation and High-grade Prostatic Intraepithelial Neoplasia in the Era of Multiparametric Magnetic Resonance Imaging: A Contemporary Review.

Manning TG, Cheung E, Perera M, Christidis D, O'Brien JS, Mitchell C, Bolton DM, Lawrentschuk N.

Urology. 2017 Sep;107:5-10. doi: 10.1016/j.urology.2017.04.021. Epub 2017 Apr 21. Review.

PMID:
28438627
6.

Differential cytotoxic and inflammatory potency of amorphous silicon dioxide nanoparticles of similar size in multiple cell lines.

Breznan D, Das DD, O'Brien JS, MacKinnon-Roy C, Nimesh S, Vuong NQ, Bernatchez S, DeSilva N, Hill M, Kumarathasan P, Vincent R.

Nanotoxicology. 2017 Mar;11(2):223-235. doi: 10.1080/17435390.2017.1287313. Epub 2017 Feb 20.

PMID:
28142331
7.

Behavioral Changes Associated with a Disruptive New Student in the Classroom.

OʼBrien JS, Taras H, Barton S, Sellick P, Stein MT.

J Dev Behav Pediatr. 2017 Feb/Mar;38 Suppl 1:S38-S40. doi: 10.1097/DBP.0000000000000175.

PMID:
28141717
8.

Penile Cancer: Contemporary Lymph Node Management.

O'Brien JS, Perera M, Manning T, Bozin M, Cabarkapa S, Chen E, Lawrentschuk N.

J Urol. 2017 Jun;197(6):1387-1395. doi: 10.1016/j.juro.2017.01.059. Epub 2017 Jan 20.

PMID:
28115191
9.

Responses of A549 human lung epithelial cells to cristobalite and α-quartz exposures assessed by toxicoproteomics and gene expression analysis.

Vuong NQ, Goegan P, De Rose F, Breznan D, Thomson EM, O'Brien JS, Karthikeyan S, Williams A, Vincent R, Kumarathasan P.

J Appl Toxicol. 2017 Jun;37(6):721-731. doi: 10.1002/jat.3420. Epub 2016 Dec 5.

10.

Discovery of Ibomycin, a Complex Macrolactone that Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function.

Robbins N, Spitzer M, Wang W, Waglechner N, Patel DJ, O'Brien JS, Ejim L, Ejim O, Tyers M, Wright GD.

Cell Chem Biol. 2016 Nov 17;23(11):1383-1394. doi: 10.1016/j.chembiol.2016.08.015. Epub 2016 Oct 13.

11.

Behavioral changes associated with a disruptive new student in the classroom.

OʼBrien JS, Taras H, Barton S, Sellick P, Stein MT.

J Dev Behav Pediatr. 2015 Jun;36(5):399-401. doi: 10.1097/DBP.0000000000000175.

PMID:
25961904
12.

Orientation-specific attachment of polymeric microtubes on cell surfaces.

Gilbert JB, O'Brien JS, Suresh HS, Cohen RE, Rubner MF.

Adv Mater. 2013 Nov 6;25(41):5948-52. doi: 10.1002/adma.201302673. Epub 2013 Aug 21.

PMID:
23963879
13.

The comprehensive antibiotic resistance database.

McArthur AG, Waglechner N, Nizam F, Yan A, Azad MA, Baylay AJ, Bhullar K, Canova MJ, De Pascale G, Ejim L, Kalan L, King AM, Koteva K, Morar M, Mulvey MR, O'Brien JS, Pawlowski AC, Piddock LJ, Spanogiannopoulos P, Sutherland AD, Tang I, Taylor PL, Thaker M, Wang W, Yan M, Yu T, Wright GD.

Antimicrob Agents Chemother. 2013 Jul;57(7):3348-57. doi: 10.1128/AAC.00419-13. Epub 2013 May 6.

14.

Regulation of gene expression in response to brain injury: enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain.

Hiraiwa M, Liu J, Lu AG, Wang CY, Misasi R, Yamauchi T, Hozumi I, Inuzuka T, O'Brien JS.

J Neurotrauma. 2003 Aug;20(8):755-65.

PMID:
12965054
15.

Discovery of beta-hexosaminidase A deficiency in Tay-Sachs disease.

Okada S, O'Brien JS.

Adv Genet. 2001;44:61-6. No abstract available.

PMID:
11596999
16.

TX14(A), a prosaposin-derived peptide, reverses established nerve disorders in streptozotocin-diabetic rats and prevents them in galactose-fed rats.

Mizisin AP, Steinhardt RC, O'Brien JS, Calcutt NA.

J Neuropathol Exp Neurol. 2001 Oct;60(10):953-60.

PMID:
11589426
17.

Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo.

Campana WM, Mohiuddin L, Misasi R, O'Brien JS, Calcutt NA.

J Peripher Nerv Syst. 2000 Sep;5(3):126-30.

PMID:
11442168
18.

Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury.

Rende M, Brizi E, Donato R, Provenzano C, Bruno R, Mizisin AP, Garrett RS, Calcutt NA, Campana WM, O'Brien JS.

Muscle Nerve. 2001 Jun;24(6):799-808.

PMID:
11360264
19.

A retro-inverso Prosaptide D5 promotes a myelination process in developing rats.

Hiraiwa M, Campana WM, Wang CY, Otero DA, O'Brien JS.

Brain Res Dev Brain Res. 2001 May 31;128(1):73-6.

PMID:
11356264
20.

A fragment of prosaposin (SGP-1) from rooster sperm promotes sperm-egg binding and improves fertility in chickens.

Hammerstedt RH, Cramer PG, Barbato GF, Amann RP, O'Brien JS, Griswold MD.

J Androl. 2001 May-Jun;22(3):361-75.

21.

Prosaptide D5, a retro-inverso 11-mer peptidomimetic, rescued dopaminergic neurons in a model of Parkinson's disease.

Liu J, Wang CY, O'Brien JS.

FASEB J. 2001 Apr;15(6):1080-2. No abstract available.

PMID:
11292674
22.

Prosaposin treatment induces PC12 entry in the S phase of the cell cycle and prevents apoptosis: activation of ERKs and sphingosine kinase.

Misasi R, Sorice M, Di Marzio L, Campana WM, Molinari S, Cifone MG, Pavan A, Pontieri GM, O'Brien JS.

FASEB J. 2001 Feb;15(2):467-74.

PMID:
11156962
23.

Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats.

Calcutt NA, Freshwater JD, O'Brien JS.

Anesthesiology. 2000 Nov;93(5):1271-8.

PMID:
11046216
24.

Retro-inverso prosaptide peptides retain bioactivity, are stable In vivo, and are blood-brain barrier permeable.

Taylor EM, Otero DA, Banks WA, O'Brien JS.

J Pharmacol Exp Ther. 2000 Oct;295(1):190-4.

PMID:
10991978
25.

Neuroprotective effect of retro-inverso Prosaptide D5 on focal cerebral ischemia in rat.

Lu AG, Otero DA, Hiraiwa M, O'Brien JS.

Neuroreport. 2000 Jun 5;11(8):1791-4.

PMID:
10852246
26.

Designing stable blood-brain barrier-permeable prosaptide peptides for treatment of central nervous system neurodegeneration.

Taylor EM, Otero DA, Banks WA, O'Brien JS.

J Pharmacol Exp Ther. 2000 May;293(2):403-9.

PMID:
10773009
27.
28.

Reversal of thermal hyperalgesia in a rat partial sciatic nerve ligation model by Prosaptide TX14(A).

Otero DA, Conrad B, O'Brien JS.

Neurosci Lett. 1999 Jul 23;270(1):29-32.

PMID:
10454138
29.

Intracellular transport of acid beta-glucosidase and lysosome-associated membrane proteins is affected in Gaucher's disease (G202R mutation).

Zimmer KP, le Coutre P, Aerts HM, Harzer K, Fukuda M, O'Brien JS, Naim HY.

J Pathol. 1999 Aug;188(4):407-14.

PMID:
10440752
30.

Phosphatidylinositol 3-kinase and Akt protein kinase mediate IGF-I- and prosaptide-induced survival in Schwann cells.

Campana WM, Darin SJ, O'Brien JS.

J Neurosci Res. 1999 Aug 1;57(3):332-41.

PMID:
10412024
31.

Administration of prosaposin ameliorates spatial learning disturbance and reduces cavity formation following stab wounds in rat brain.

Hozumi I, Hiraiwa M, Inuzuka T, Yoneoka Y, Akiyama K, Tanaka R, Kikugawa K, Nakano R, Tsuji S, O'Brien JS.

Neurosci Lett. 1999 May 21;267(1):73-6.

PMID:
10400252
32.

Prosaposin: a myelinotrophic protein that promotes expression of myelin constituents and is secreted after nerve injury.

Hiraiwa M, Campana WM, Mizisin AP, Mohiuddin L, O'Brien JS.

Glia. 1999 Jun;26(4):353-60.

PMID:
10383054
33.

Prosaposin gene expression and the efficacy of a prosaposin-derived peptide in preventing structural and functional disorders of peripheral nerve in diabetic rats.

Calcutt NA, Campana WM, Eskeland NL, Mohiuddin L, Dines KC, Mizisin AP, O'Brien JS.

J Neuropathol Exp Neurol. 1999 Jun;58(6):628-36.

PMID:
10374753
34.

Secretion of prosaposin, a multifunctional protein, by breast cancer cells.

Campana WM, O'Brien JS, Hiraiwa M, Patton S.

Biochim Biophys Acta. 1999 May 24;1427(3):392-400.

PMID:
10350655
35.

Spectrum of mutations in fucosidosis.

Willems PJ, Seo HC, Coucke P, Tonlorenzi R, O'Brien JS.

Eur J Hum Genet. 1999 Jan;7(1):60-7. Review.

36.

Identification of a neurotrophic sequence in erythropoietin.

Campana WM, Misasi R, O'Brien JS.

Int J Mol Med. 1998 Jan;1(1):235-41.

PMID:
9852225
37.

Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells.

Misasi R, Sorice M, Garofalo T, Griggi T, Campana WM, Giammatteo M, Pavan A, Hiraiwa M, Pontieri GM, O'Brien JS.

J Neurochem. 1998 Dec;71(6):2313-21.

38.

Prosaptide prevents hyperalgesia and reduces peripheral TNFR1 expression following TNF-alpha nerve injection.

Wagner R, Myers RR, O'Brien JS.

Neuroreport. 1998 Aug 24;9(12):2827-31.

PMID:
9760128
39.

Prosaposin prevents programmed cell death of rat cerebellar granule neurons in culture.

Tsuboi K, Hiraiwa M, O'Brien JS.

Brain Res Dev Brain Res. 1998 Oct 1;110(2):249-55.

PMID:
9748612
40.

Prosaptide prevents paclitaxel neurotoxicity.

Campana WM, Eskeland N, Calcutt NA, Misasi R, Myers RR, O'Brien JS.

Neurotoxicology. 1998 Apr;19(2):237-44.

PMID:
9553960
41.

Cloning, expression and map assignment of chicken prosaposin.

Azuma N, Seo HC, Lie O, Fu Q, Gould RM, Hiraiwa M, Burt DW, Paton IR, Morrice DR, O'Brien JS, Kishimoto Y.

Biochem J. 1998 Feb 15;330 ( Pt 1):321-7.

42.
43.

Saposins (sap) A and C activate the degradation of galactosylceramide in living cells.

Harzer K, Paton BC, Christomanou H, Chatelut M, Levade T, Hiraiwa M, O'Brien JS.

FEBS Lett. 1997 Nov 17;417(3):270-4.

44.

Prosaposin receptor: evidence for a G-protein-associated receptor.

Hiraiwa M, Campana WM, Martin BM, O'Brien JS.

Biochem Biophys Res Commun. 1997 Nov 17;240(2):415-8.

PMID:
9388493
45.

Protective protein in the bovine lysosomal beta-galactosidase complex.

Hiraiwa M, Saitoh M, Arai N, Shiraishi T, Odani S, Uda Y, Ono T, O'Brien JS.

Biochim Biophys Acta. 1997 Sep 5;1341(2):189-99.

PMID:
9357958
46.

Model SV40-transformed fibroblast lines for metabolic studies of human prosaposin and acid ceramidase deficiencies.

Chatelut M, Harzer K, Christomanou H, Feunteun J, Pieraggi MT, Paton BC, Kishimoto Y, O'Brien JS, Basile JP, Thiers JC, Salvayre R, Levade T.

Clin Chim Acta. 1997 Jun 27;262(1-2):61-76.

PMID:
9204210
47.

Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): its mechanism and inhibition by ganglioside.

Hiraiwa M, Martin BM, Kishimoto Y, Conner GE, Tsuji S, O'Brien JS.

Arch Biochem Biophys. 1997 May 1;341(1):17-24.

PMID:
9143348
48.
49.

Prosaposin, a neurotrophic factor: presence and properties in milk.

Patton S, Carson GS, Hiraiwa M, O'Brien JS, Sano A.

J Dairy Sci. 1997 Feb;80(2):264-72.

50.

Induction of MAPK phosphorylation by prosaposin and prosaptide in PC12 cells.

Campana WM, Hiraiwa M, Addison KC, O'Brien JS.

Biochem Biophys Res Commun. 1996 Dec 24;229(3):706-12.

PMID:
8954961

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