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The expansion of targetable biomarkers for CAR T cell therapy. Townsend MH et al. J Exp Clin Cancer Res. (2018)

A review of HPRT and its emerging role in cancer. Townsend MH et al. Med Oncol. (2018)

A practical approach in bioreactor scale-up and process transfer using a combination of constant P/V and vvm as the criterion. Xu S et al. Biotechnol Prog. (2017)

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Items: 1 to 50 of 582


Effect of advanced glycation end-products (AGE) lowering drug ALT-711 on biochemical, vascular, and bone parameters in a rat model of CKD-MBD.

Chen NX, Srinivasan S, O'Neill K, Nickolas TL, Wallace JM, Allen MR, Metzger CE, Creecy A, Avin KG, Moe SM.

J Bone Miner Res. 2019 Nov 19. doi: 10.1002/jbmr.3925. [Epub ahead of print]


Poor availability of essential medicines for women and children threatens progress towards Sustainable Development Goal 3 in Africa.

Droti B, O'Neill KP, Mathai M, Yao Tsidi Dovlo D, Robertson J.

BMJ Glob Health. 2019 Oct 5;4(Suppl 9):e001306. doi: 10.1136/bmjgh-2018-001306. eCollection 2019.


Generating statistics from health facility data: the state of routine health information systems in Eastern and Southern Africa.

Maïga A, Jiwani SS, Mutua MK, Porth TA, Taylor CM, Asiki G, Melesse DY, Day C, Strong KL, Faye CM, Viswanathan K, O'Neill KP, Amouzou A, Pond BS, Boerma T.

BMJ Glob Health. 2019 Sep 29;4(5):e001849. doi: 10.1136/bmjgh-2019-001849. eCollection 2019. Review.


BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.

Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X.

Cell Res. 2019 Nov;29(11):942-952. doi: 10.1038/s41422-019-0231-y. Epub 2019 Sep 24.


Voluntary Wheel Running Has Beneficial Effects in a Rat Model of CKD-Mineral Bone Disorder (CKD-MBD).

Avin KG, Allen MR, Chen NX, Srinivasan S, O'Neill KD, Troutman AD, Mast G, Swallow EA, Brown MB, Wallace JM, Zimmers TA, Warden SJ, Moe SM.

J Am Soc Nephrol. 2019 Oct;30(10):1898-1909. doi: 10.1681/ASN.2019040349. Epub 2019 Sep 9.


Integrated systems-genetic analyses reveal a network target for delaying glioma progression.

Laaniste L, Srivastava PK, Stylianou J, Syed N, Cases-Cunillera S, Shkura K, Zeng Q, Rackham OJL, Langley SR, Delahaye-Duriez A, O'Neill K, Williams M, Becker A, Roncaroli F, Petretto E, Johnson MR.

Ann Clin Transl Neurol. 2019 Sep;6(9):1616-1638. doi: 10.1002/acn3.50850. Epub 2019 Aug 17.


Composition of airway bacterial community correlates with chest HRCT in adults with bronchiectasis.

O'Neill K, Einarsson GG, Rowan S, McIlreavey L, Lee AJ, Lawson J, Lynch T, Horsley A, Bradley JM, Elborn JS, Tunney MM.

Respirology. 2019 Jul 30. doi: 10.1111/resp.13653. [Epub ahead of print]


Wildflower Seed Sales as Incentive for Adopting Flower Strips for Native Bee Conservation: A Cost-Benefit Analysis.

Delphia CM, O'Neill KM, Burkle LA.

J Econ Entomol. 2019 Jul 18. pii: toz191. doi: 10.1093/jee/toz191. [Epub ahead of print]


Ground-Dwelling Arthropod Community Response to Livestock Grazing: Implications for Avian Conservation.

Goosey HB, Smith JT, O'Neill KM, Naugle DE.

Environ Entomol. 2019 Aug 5;48(4):856-866. doi: 10.1093/ee/nvz074.


Encapsulation of Temozolomide in a Calixarene Nanocapsule Improves Its Stability and Enhances Its Therapeutic Efficacy against Glioblastoma.

Renziehausen A, Tsiailanis AD, Perryman R, Stylos EK, Chatzigiannis C, O'Neill K, Crook T, Tzakos AG, Syed N.

Mol Cancer Ther. 2019 Sep;18(9):1497-1505. doi: 10.1158/1535-7163.MCT-18-1250. Epub 2019 Jun 18.


Dryland Organic Farming Partially Offsets Negative Effects of Highly Simplified Agricultural Landscapes on Forbs, Bees, and Bee-Flower Networks.

Adhikari S, Burkle LA, O'Neill KM, Weaver DK, Delphia CM, Menalled FD.

Environ Entomol. 2019 Aug 5;48(4):826-835. doi: 10.1093/ee/nvz056.


Falling from grace: HPRT is not suitable as an endogenous control for cancer-related studies.

Townsend MH, Felsted AM, Ence ZE, Piccolo SR, Robison RA, O'Neill KL.

Mol Cell Oncol. 2019 Feb 26;6(2):1575691. doi: 10.1080/23723556.2019.1575691. eCollection 2019.


Ten simple rules for providing a meaningful research experience to high school students.

Lescak EA, O'Neill KM, Collu GM, Das S.

PLoS Comput Biol. 2019 Apr 25;15(4):e1006920. doi: 10.1371/journal.pcbi.1006920. eCollection 2019 Apr. No abstract available.


NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischaemic revascularisation.

O'Neill KM, Campbell DC, Edgar KS, Gill EK, Moez A, McLoughlin KJ, O'Neill CL, Dellett M, Hargey CJ, Abudalo RA, O'Hare M, Doyle P, Toh T, Khoo J, Wong J, McCrudden CM, Meloni M, Brunssen C, Morawietz H, Yoder MC, McDonald DM, Watson CJ, Stitt AW, Margariti A, Medina RJ, Grieve DJ.

Cardiovasc Res. 2019 Apr 1. pii: cvz090. doi: 10.1093/cvr/cvz090. [Epub ahead of print]


Assessment of stability and fluctuations of cultured lower airway bacterial communities in people with cystic fibrosis.

Sherrard LJ, Einarsson GG, Johnston E, O'Neill K, McIlreavey L, McGrath SJ, Gilpin DF, Downey DG, Reid A, McElvaney NG, Boucher RC, Muhlebach MS, Elborn JS, Tunney MM.

J Cyst Fibros. 2019 Mar 21. pii: S1569-1993(19)30052-9. doi: 10.1016/j.jcf.2019.02.012. [Epub ahead of print]


Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane.

Farmer T, O'Neill KL, Naslavsky N, Luo X, Caplan S.

Mol Biol Cell. 2019 May 1;30(10):1138-1146. doi: 10.1091/mbc.E19-01-0044. Epub 2019 Mar 6.


A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma.

Hall PE, Lewis R, Syed N, Shaffer R, Evanson J, Ellis S, Williams M, Feng X, Johnston A, Thomson JA, Harris FP, Jena R, Matys T, Jefferies S, Smith K, Wu BW, Bomalaski JS, Crook T, O'Neill K, Paraskevopoulos D, Khadeir RS, Sheaff M, Pacey S, Plowman PN, Szlosarek PW.

Clin Cancer Res. 2019 May 1;25(9):2708-2716. doi: 10.1158/1078-0432.CCR-18-3729. Epub 2019 Feb 22.


Correction to: Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies.

Weagel EG, Burrup W, Kovtun R, Velazquez EJ, Felsted AM, Townsend MH, Ence ZE, Suh E, Piccolo SR, Weber KS, Robison RA, O'Neill KL.

Cancer Cell Int. 2019 Feb 11;19:29. doi: 10.1186/s12935-019-0749-6. eCollection 2019.


Checklist of bees (Hymenoptera: Apoidea) from small diversified vegetable farms in south-western Montana.

Delphia CM, Griswold T, Reese EG, O'Neill KM, Burkle LA.

Biodivers Data J. 2019 Jan 28;(7):e30062. doi: 10.3897/BDJ.7.e30062. eCollection 2019.


The growing role of precision and personalized medicine for cancer treatment.

Krzyszczyk P, Acevedo A, Davidoff EJ, Timmins LM, Marrero-Berrios I, Patel M, White C, Lowe C, Sherba JJ, Hartmanshenn C, O'Neill KM, Balter ML, Fritz ZR, Androulakis IP, Schloss RS, Yarmush ML.

Technology (Singap World Sci). 2018 Sep-Dec;6(3-4):79-100. doi: 10.1142/S2339547818300020. Epub 2019 Jan 11.


Potential new biomarkers for endometrial cancer.

Townsend MH, Ence ZE, Felsted AM, Parker AC, Piccolo SR, Robison RA, O'Neill KL.

Cancer Cell Int. 2019 Jan 21;19:19. doi: 10.1186/s12935-019-0731-3. eCollection 2019.


Airway clearance, mucoactive therapies and pulmonary rehabilitation in bronchiectasis.

O'Neill K, O'Donnell AE, Bradley JM.

Respirology. 2019 Mar;24(3):227-237. doi: 10.1111/resp.13459. Epub 2019 Jan 16. Review.


Single cell analyses reveal specific distribution of anti-bacterial molecule Perforin-2 in human skin and its modulation by wounding and Staphylococcus aureus infection.

Strbo N, Pastar I, Romero L, Chen V, Vujanac M, Sawaya AP, Jozic I, Ferreira ADF, Wong LL, Head C, Stojadinovic O, Garcia D, O'Neill K, Drakulich S, Taller S, Kirsner RS, Tomic-Canic M.

Exp Dermatol. 2019 Mar;28(3):225-232. doi: 10.1111/exd.13870. Epub 2019 Feb 12.


Study of the cyanoacrylate fuming mechanism by matrix-assisted laser desorption/ionization mass spectrometry.

O'Neill KC, Lee YJ.

J Mass Spectrom. 2019 Mar;54(3):222-226. doi: 10.1002/jms.4325.


Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.

Przystal JM, Hajji N, Khozoie C, Renziehausen A, Zeng Q, Abaitua F, Hajitou A, Suwan K, Want E, Bomalaski J, Szlosarek P, O'Neill K, Crook T, Syed N.

Cell Death Dis. 2018 Dec 13;9(12):1192. doi: 10.1038/s41419-018-1195-4.


Quality control for multiple breath washout tests in multicentre bronchiectasis studies: Experiences from the BRONCH-UK clinimetrics study.

O'Neill K, Lakshmipathy GR, Ferguson K, Cosgrove D, Hill AT, Loebinger MR, Carroll M, Chalmers JD, Gatheral T, Johnson C, DeSoyza A, Hurst JR, Bradbury I, Elborn JS, Bradley JM.

Respir Med. 2018 Dec;145:206-211. doi: 10.1016/j.rmed.2018.10.030. Epub 2018 Nov 1.


The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.

Renziehausen A, Wang H, Rao B, Weir L, Nigro CL, Lattanzio L, Merlano M, Vega-Rioja A, Del Carmen Fernandez-Carranco M, Hajji N, Matin R, Harwood C, Li S, Sim VR, O'Neill K, Evans A, Thompson A, Szlosarek P, Fleming C, Stebbing J, Proby C, Tzakos AG, Syed N, Crook T.

Oncogene. 2019 Mar;38(13):2320-2336. doi: 10.1038/s41388-018-0563-y. Epub 2018 Nov 26.


Enhanced Function of Induced Pluripotent Stem Cell-Derived Endothelial Cells Through ESM1 Signaling.

Vilà-González M, Kelaini S, Magee C, Caines R, Campbell D, Eleftheriadou M, Cochrane A, Drehmer D, Tsifaki M, O'Neill K, Pedrini E, Yang C, Medina R, McDonald D, Simpson D, Zampetaki A, Zeng L, Grieve D, Lois N, Stitt AW, Margariti A.

Stem Cells. 2019 Feb;37(2):226-239. doi: 10.1002/stem.2936. Epub 2018 Nov 17.


Impact of Empowering Leadership on Antimicrobial Stewardship: A Single Center Study in a Neonatal and Pediatric Intensive Care Unit and a Literature Review.

Steinmann KE, Lehnick D, Buettcher M, Schwendener-Scholl K, Daetwyler K, Fontana M, Morgillo D, Ganassi K, O'Neill K, Genet P, Burth S, Savoia P, Terheggen U, Berger C, Stocker M.

Front Pediatr. 2018 Oct 12;6:294. doi: 10.3389/fped.2018.00294. eCollection 2018.


TEsmall Identifies Small RNAs Associated With Targeted Inhibitor Resistance in Melanoma.

O'Neill K, Liao WW, Patel A, Hammell MG.

Front Genet. 2018 Oct 5;9:461. doi: 10.3389/fgene.2018.00461. eCollection 2018.


Examination of Hypoxanthine Guanine Phosphoribosyltransferase as a biomarker for colorectal cancer patients.

Townsend MH, Felsted AM, Burrup W, Robison RA, O'Neill KL.

Mol Cell Oncol. 2018 Aug 1;5(4):e1481810. doi: 10.1080/23723556.2018.1481810. eCollection 2018.


Effects of treadmill running in a rat model of chronic kidney disease.

Organ JM, Allen MR, Myers-White A, Elkhatib W, O'Neill KD, Chen NX, Moe SM, Avin KG.

Biochem Biophys Rep. 2018 Sep 14;16:19-23. doi: 10.1016/j.bbrep.2018.09.001. eCollection 2018 Dec.


Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies.

Weagel EG, Burrup W, Kovtun R, Velazquez EJ, Felsted AM, Townsend MH, Ence ZE, Suh E, Piccolo SR, Weber KS, Robison RA, O'Neill KL.

Cancer Cell Int. 2018 Sep 10;18:135. doi: 10.1186/s12935-018-0633-9. eCollection 2018. Erratum in: Cancer Cell Int. 2019 Feb 11;19:29.


Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression.

Rogers TJ, Christenson JL, Greene LI, O'Neill KI, Williams MM, Gordon MA, Nemkov T, D'Alessandro A, Degala GD, Shin J, Tan AC, Cittelly DM, Lambert JR, Richer JK.

Mol Cancer Res. 2019 Jan;17(1):30-41. doi: 10.1158/1541-7786.MCR-18-0246. Epub 2018 Sep 13.


Gestational Diabetes Alters the Metabolomic Profile in 2nd Trimester Amniotic Fluid in a Sex-Specific Manner.

O'Neill K, Alexander J, Azuma R, Xiao R, Snyder NW, Mesaros CA, Blair IA, Pinney SE.

Int J Mol Sci. 2018 Sep 10;19(9). pii: E2696. doi: 10.3390/ijms19092696.


In Defense of Family Leave in Surgical Residency.

O'Neill KM, Horowitz NR, Yoo PS.

J Grad Med Educ. 2018 Aug;10(4):392-393. doi: 10.4300/JGME-D-17-00716.1. No abstract available.


Health service utilization and related costs attributable to diabetes.

O'Neill KN, McHugh SM, Tracey ML, Fitzgerald AP, Kearney PM.

Diabet Med. 2018 Dec;35(12):1727-1734. doi: 10.1111/dme.13806. Epub 2018 Sep 19.


Correction to: Mother and Home Visitor Emotional Well-Being and Alignment on Goals for Home Visiting as Factors for Program Engagement.

Burrell L, Crowne S, Ojo K, Snead R, O'Neill K, Cluxton-Keller F, Duggan A.

Matern Child Health J. 2018 Oct;22(Suppl 1):119. doi: 10.1007/s10995-018-2621-z.


Correction to: Randomized Trial of a Training Program to Improve Home Visitor Communication around Sensitive Topics.

West A, Gagliardi L, Gatewood A, Higman S, Daniels J, O'Neill K, Duggan A.

Matern Child Health J. 2018 Oct;22(Suppl 1):122. doi: 10.1007/s10995-018-2624-9.


High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations.

Hui T, Cao Q, Wegrzyn-Woltosz J, O'Neill K, Hammond CA, Knapp DJHF, Laks E, Moksa M, Aparicio S, Eaves CJ, Karsan A, Hirst M.

Stem Cell Reports. 2018 Aug 14;11(2):578-592. doi: 10.1016/j.stemcr.2018.07.003. Epub 2018 Aug 2.


Comparison of DNMT1 inhibitors by methylome profiling identifies unique signature of 5-aza-2'deoxycytidine.

Mackin SJ, O'Neill KM, Walsh CP.

Epigenomics. 2018 Aug;10(8):1085-1101. doi: 10.2217/epi-2017-0171. Epub 2018 Aug 2.


Framework and strategy for integrated monitoring and evaluation of child health programmes for responsive programming, accountability, and impact.

Diaz T, Rasanathan K, Meribole E, Maina I, Nsona H, Aung KM, Nemser B, O'Neill KP.

BMJ. 2018 Jul 30;362:k2785. doi: 10.1136/bmj.k2785. Review. No abstract available.


The expansion of targetable biomarkers for CAR T cell therapy.

Townsend MH, Shrestha G, Robison RA, O'Neill KL.

J Exp Clin Cancer Res. 2018 Jul 21;37(1):163. doi: 10.1186/s13046-018-0817-0. Review.


Impact of a Child Abuse Primary Prevention Strategy for New Mothers.

O'Neill KMG, Cluxton-Keller F, Burrell L, Crowne SS, Duggan A.

Prev Sci. 2018 Jul 9. doi: 10.1007/s11121-018-0925-2. [Epub ahead of print]


Maintaining Safety and Improving the Care of Pediatric Behavioral Health Patients in the Emergency Department.

Stricker FR, O'Neill KB, Merson J, Feuer V.

Child Adolesc Psychiatr Clin N Am. 2018 Jul;27(3):427-439. doi: 10.1016/j.chc.2018.03.005. Epub 2018 Apr 19. Review.


The bitter side of epigenetics: variability and resistance to chemotherapy.

Hajji N, García-Domínguez DJ, Hontecillas-Prieto L, O'Neill K, de Álava E, Syed N.

Epigenomics. 2018 Jun 22. doi: 10.2217/epi-2017-0112. [Epub ahead of print]


Randomized Trial of a Training Program to Improve Home Visitor Communication around Sensitive Topics.

West A, Gagliardi L, Gatewood A, Higman S, Daniels J, O'Neill K, Duggan A.

Matern Child Health J. 2018 Oct;22(Suppl 1):70-78. doi: 10.1007/s10995-018-2531-0. Erratum in: Matern Child Health J. 2018 Aug 22;:.


Mother and Home Visitor Emotional Well-Being and Alignment on Goals for Home Visiting as Factors for Program Engagement.

Burrell L, Crowne S, Ojo K, Snead R, O'Neill K, Cluxton-Keller F, Duggan A.

Matern Child Health J. 2018 Oct;22(Suppl 1):43-51. doi: 10.1007/s10995-018-2535-9. Erratum in: Matern Child Health J. 2018 Aug 22;:.


The influence of sociodemographic factors on operative decision-making in small bowel obstruction.

Jean RA, Chiu AS, O'Neill KM, Lin Z, Pei KY.

J Surg Res. 2018 Jul;227:137-144. doi: 10.1016/j.jss.2018.02.029. Epub 2018 Mar 15.


Discovery of MK-8282 as a Potent G-Protein-Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes.

Neelamkavil SF, Stamford AW, Kowalski T, Biswas D, Boyle C, Chackalamannil S, Xia Y, Jayne C, Neustadt B, Hao J, Liu H, Dai X, Baker H, Hawes B, O'Neill K, Tang H, Greenlee WJ.

ACS Med Chem Lett. 2018 Apr 10;9(5):457-461. doi: 10.1021/acsmedchemlett.8b00073. eCollection 2018 May 10.

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