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Timing's everything in light, location, and cells.

O'Leary HA.

Blood. 2019 Jan 17;133(3):186-187. doi: 10.1182/blood-2018-11-883462. No abstract available.


BEAPP: The Batch Electroencephalography Automated Processing Platform.

Levin AR, Méndez Leal AS, Gabard-Durnam LJ, O'Leary HM.

Front Neurosci. 2018 Aug 7;12:513. doi: 10.3389/fnins.2018.00513. eCollection 2018.


Pain sensitization associated with nonresponse after physiotherapy in people with knee osteoarthritis.

OʼLeary H, Smart KM, Moloney NA, Blake C, Doody CM.

Pain. 2018 Sep;159(9):1877-1886. doi: 10.1097/j.pain.0000000000001288.


Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation.

Cook SG, Bourke AM, O'Leary H, Zaegel V, Lasda E, Mize-Berge J, Quillinan N, Tucker CL, Coultrap SJ, Herson PS, Bayer KU.

Sci Rep. 2018 Apr 3;8(1):5448. doi: 10.1038/s41598-018-23779-4.


Placebo-controlled crossover assessment of mecasermin for the treatment of Rett syndrome.

O'Leary HM, Kaufmann WE, Barnes KV, Rakesh K, Kapur K, Tarquinio DC, Cantwell NG, Roche KJ, Rose SA, Walco AC, Bruck NM, Bazin GA, Holm IA, Alexander ME, Swanson LC, Baczewski LM, Mayor Torres JM, Nelson CA 3rd, Sahin M.

Ann Clin Transl Neurol. 2018 Jan 31;5(3):323-332. doi: 10.1002/acn3.533. eCollection 2018 Mar. Erratum in: Ann Clin Transl Neurol. 2018 Jul 13;5(7):895.


Current concepts in joint pain in knee osteoarthritis.

Mills K, Hübscher M, O'Leary H, Moloney N.

Schmerz. 2019 Feb;33(1):22-29. doi: 10.1007/s00482-018-0275-9. Review.


High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation.

Farag SS, Nelson R, Cairo MS, O'Leary HA, Zhang S, Huntley C, Delgado D, Schwartz J, Zaid MA, Abonour R, Robertson M, Broxmeyer H.

Oncotarget. 2017 Nov 27;8(66):110350-110357. doi: 10.18632/oncotarget.22739. eCollection 2017 Dec 15.


CaMKII regulates the depalmitoylation and synaptic removal of the scaffold protein AKAP79/150 to mediate structural long-term depression.

Woolfrey KM, O'Leary H, Goodell DJ, Robertson HR, Horne EA, Coultrap SJ, Dell'Acqua ML, Bayer KU.

J Biol Chem. 2018 Feb 2;293(5):1551-1567. doi: 10.1074/jbc.M117.813808. Epub 2017 Dec 1. Review.


Classification of respiratory disturbances in Rett Syndrome patients using Restricted Boltzmann Machine.

O'Leary HM, Mayor JM, Chi-Sang Poon, Kaufmann WE, Sahin M.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:442-445. doi: 10.1109/EMBC.2017.8036857.


Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in non-del(17p) CLL.

Appleby N, O'Brien D, Quinn FM, Smyth L, Kelly J, Parker I, Scott K, Cahill MR, Crotty G, Enright H, Hennessy B, Hodgson A, Leahy M, O'Leary H, O'Dwyer M, Hayat A, Vandenberghe EA.

Leuk Lymphoma. 2018 Jun;59(6):1338-1347. doi: 10.1080/10428194.2017.1376746. Epub 2017 Sep 19.


EEG power at 3 months in infants at high familial risk for autism.

Levin AR, Varcin KJ, O'Leary HM, Tager-Flusberg H, Nelson CA.

J Neurodev Disord. 2017 Sep 13;9(1):34. doi: 10.1186/s11689-017-9214-9.


Defining Hand Stereotypies in Rett Syndrome: A Movement Disorders Perspective.

Dy ME, Waugh JL, Sharma N, O'Leary H, Kapur K, D'Gama AM, Sahin M, Urion DK, Kaufmann WE.

Pediatr Neurol. 2017 Oct;75:91-95. doi: 10.1016/j.pediatrneurol.2017.05.025. Epub 2017 Jun 2.


Utility of CRISPR/Cas9 systems in hematology research.

Lucas D, O'Leary HA, Ebert BL, Cowan CA, Tremblay CS.

Exp Hematol. 2017 Oct;54:1-3. doi: 10.1016/j.exphem.2017.06.006. Epub 2017 Jun 28. Review.


DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.

O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE.

Leukemia. 2017 Nov;31(11):2468-2478. doi: 10.1038/leu.2017.98. Epub 2017 Mar 27.


Nervous System Sensitization as a Predictor of Outcome in the Treatment of Peripheral Musculoskeletal Conditions: A Systematic Review.

O'Leary H, Smart KM, Moloney NA, Doody CM.

Pain Pract. 2017 Feb;17(2):249-266. doi: 10.1111/papr.12484. Epub 2016 Aug 19. Review.


Enhanced long term potentiation and decreased AMPA receptor desensitization in the acute period following a single kainate induced early life seizure.

O'Leary H, Bernard PB, Castano AM, Benke TA.

Neurobiol Dis. 2016 Mar;87:134-44. doi: 10.1016/j.nbd.2015.12.005. Epub 2015 Dec 17.


Detecting autonomic response to pain in Rett syndrome.

O'Leary HM, Marschik PB, Khwaja OS, Ho E, Barnes KV, Clarkson TW, Bruck NM, Kaufmann WE.

Dev Neurorehabil. 2017 Feb;20(2):108-114. doi: 10.3109/17518423.2015.1087437. Epub 2015 Oct 12.


Anxiety-like behavior in Rett syndrome: characteristics and assessment by anxiety scales.

Barnes KV, Coughlin FR, O'Leary HM, Bruck N, Bazin GA, Beinecke EB, Walco AC, Cantwell NG, Kaufmann WE.

J Neurodev Disord. 2015;7(1):30. doi: 10.1186/s11689-015-9127-4. Epub 2015 Sep 15.


Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.

Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, Fitamant J, Ivan M, Kim KS, Broxmeyer HE.

Cell. 2015 Jun 18;161(7):1553-65. doi: 10.1016/j.cell.2015.04.054. Epub 2015 Jun 11.


Pain sensitisation and the risk of poor outcome following physiotherapy for patients with moderate to severe knee osteoarthritis: protocol for a prospective cohort study.

O'Leary H, Smart KM, Moloney NA, Blake C, Doody CM.

BMJ Open. 2015 Jun 9;5(6):e007430. doi: 10.1136/bmjopen-2014-007430.


Pneumocystis jiroveci prophylaxis in patients undergoing Bendamustine treatment: the need for a standardized protocol.

Abkur TM, Saeed M, Ahmed SZ, McArthur R, Leahy M, O'Leary H, O'Keeffe D.

Clin Case Rep. 2015 Apr;3(4):255-9. doi: 10.1002/ccr3.195. Epub 2015 Feb 9.


Age of diagnosis in Rett syndrome: patterns of recognition among diagnosticians and risk factors for late diagnosis.

Tarquinio DC, Hou W, Neul JL, Lane JB, Barnes KV, O'Leary HM, Bruck NM, Kaufmann WE, Motil KJ, Glaze DG, Skinner SA, Annese F, Baggett L, Barrish JO, Geerts SP, Percy AK.

Pediatr Neurol. 2015 Jun;52(6):585-91.e2. doi: 10.1016/j.pediatrneurol.2015.02.007. Epub 2015 Feb 16.


Autonomous CaMKII requires further stimulation by Ca2+/calmodulin for enhancing synaptic strength.

Barcomb K, Buard I, Coultrap SJ, Kulbe JR, O'Leary H, Benke TA, Bayer KU.

FASEB J. 2014 Aug;28(8):3810-9. doi: 10.1096/fj.14-250407. Epub 2014 May 19.


Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome.

Khwaja OS, Ho E, Barnes KV, O'Leary HM, Pereira LM, Finkelstein Y, Nelson CA 3rd, Vogel-Farley V, DeGregorio G, Holm IA, Khatwa U, Kapur K, Alexander ME, Finnegan DM, Cantwell NG, Walco AC, Rappaport L, Gregas M, Fichorova RN, Shannon MW, Sur M, Kaufmann WE.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4596-601. doi: 10.1073/pnas.1311141111. Epub 2014 Mar 12.


Autonomous CaMKII mediates both LTP and LTD using a mechanism for differential substrate site selection.

Coultrap SJ, Freund RK, O'Leary H, Sanderson JL, Roche KW, Dell'Acqua ML, Bayer KU.

Cell Rep. 2014 Feb 13;6(3):431-7. doi: 10.1016/j.celrep.2014.01.005. Epub 2014 Jan 30.


A multi-centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia.

Maung SW, Leahy M, O'Leary HM, Khan I, Cahill MR, Gilligan O, Murphy P, McPherson S, Jackson F, Ryan M, Hennessy B, McHugh J, Goodyer M, Bacon L, O'Gorman P, Nee A, O'Dwyer M, Enright H, Saunders J, O'Keeffe D.

Br J Haematol. 2013 Oct;163(1):118-22. doi: 10.1111/bjh.12486. Epub 2013 Aug 2.


Contribution of electromechanical coupling between Kv and Ca v1.2 channels to coronary dysfunction in obesity.

Berwick ZC, Dick GM, O'Leary HA, Bender SB, Goodwill AG, Moberly SP, Owen MK, Miller SJ, Obukhov AG, Tune JD.

Basic Res Cardiol. 2013 Sep;108(5):370. doi: 10.1007/s00395-013-0370-0. Epub 2013 Jul 16.


Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.

Bernard PB, Castano AM, O'Leary H, Simpson K, Browning MD, Benke TA.

Neurobiol Dis. 2013 Nov;59:1-17. doi: 10.1016/j.nbd.2013.06.013. Epub 2013 Jul 2.


Concise review: role of DEK in stem/progenitor cell biology.

Broxmeyer HE, Mor-Vaknin N, Kappes F, Legendre M, Saha AK, Ou X, O'Leary H, Capitano M, Cooper S, Markovitz DM.

Stem Cells. 2013 Aug;31(8):1447-53. doi: 10.1002/stem.1443. Review.


Implications of DPP4 modification of proteins that regulate stem/progenitor and more mature cell types.

Ou X, O'Leary HA, Broxmeyer HE.

Blood. 2013 Jul 11;122(2):161-9. doi: 10.1182/blood-2013-02-487470. Epub 2013 May 1. Review.


The role of dipeptidyl peptidase 4 in hematopoiesis and transplantation.

O'Leary H, Ou X, Broxmeyer HE.

Curr Opin Hematol. 2013 Jul;20(4):314-9. doi: 10.1097/MOH.0b013e32836125ac. Review.


Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis.

Broxmeyer HE, Hoggatt J, O'Leary HA, Mantel C, Chitteti BR, Cooper S, Messina-Graham S, Hangoc G, Farag S, Rohrabaugh SL, Ou X, Speth J, Pelus LM, Srour EF, Campbell TB.

Nat Med. 2012 Dec;18(12):1786-96. doi: 10.1038/nm.2991. Epub 2012 Nov 18.


Continuous quantitative monitoring of cerebral oxygen metabolism in neonates by ventilator-gated analysis of NIRS recordings.

Heldt T, Kashif FM, Sulemanji M, O'Leary HM, du Plessis AJ, Verghese GC.

Acta Neurochir Suppl. 2012;114:177-80. doi: 10.1007/978-3-7091-0956-4_34.


Bone marrow osteoblast damage by chemotherapeutic agents.

Rellick SL, O'Leary H, Piktel D, Walton C, Fortney JE, Akers SM, Martin KH, Denvir J, Boskovic G, Primerano DA, Vos J, Bailey N, Gencheva M, Gibson LF.

PLoS One. 2012;7(2):e30758. doi: 10.1371/journal.pone.0030758. Epub 2012 Feb 17.


Nucleotides and phosphorylation bi-directionally modulate Ca2+/calmodulin-dependent protein kinase II (CaMKII) binding to the N-methyl-D-aspartate (NMDA) receptor subunit GluN2B.

O'Leary H, Liu WH, Rorabaugh JM, Coultrap SJ, Bayer KU.

J Biol Chem. 2011 Sep 9;286(36):31272-81. doi: 10.1074/jbc.M111.233668. Epub 2011 Jul 18.


VE-cadherin Regulates Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Sensitivity to Apoptosis.

O'Leary H, Akers SM, Piktel D, Walton C, Fortney JE, Martin KH, Craig M, Coad J, Gibson LF.

Cancer Microenviron. 2010 Mar 2;3(1):67-81. doi: 10.1007/s12307-010-0035-6.


VE-cadherin and PECAM-1 enhance ALL migration across brain microvascular endothelial cell monolayers.

Akers SM, O'Leary HA, Minnear FL, Craig MD, Vos JA, Coad JE, Gibson LF.

Exp Hematol. 2010 Sep;38(9):733-43. doi: 10.1016/j.exphem.2010.05.001. Epub 2010 May 12.


T-lymphoblastic leukemia/lymphoma: a single center retrospective study of outcome.

Fortune A, O'Leary H, Gilmore R, Chadwick N, Brennan L, Ní Chonghaile M, McCann SR, Browne PV, Conneally E, Vandenberghe E.

Leuk Lymphoma. 2010 Jun;51(6):1035-9. doi: 10.3109/10428191003754616.


Update on the World Health Organization classification of peripheral T-cell lymphomas.

O'Leary HM, Savage KJ.

Curr Hematol Malig Rep. 2009 Oct;4(4):227-35. doi: 10.1007/s11899-009-0030-5. Review.


Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor.

Vest RS, O'Leary H, Coultrap SJ, Kindy MS, Bayer KU.

J Biol Chem. 2010 Jul 2;285(27):20675-82. doi: 10.1074/jbc.M109.088617. Epub 2010 Apr 27.


Neurotrophins regulate bone marrow stromal cell IL-6 expression through the MAPK pathway.

Rezaee F, Rellick SL, Piedimonte G, Akers SM, O'Leary HA, Martin K, Craig MD, Gibson LF.

PLoS One. 2010 Mar 15;5(3):e9690. doi: 10.1371/journal.pone.0009690.


Use of SAG-M-suspended red cell concentrate in large volume transfusion associated with cardiac surgery in neonates and infants: a retrospective audit.

Bond J, O'Leary H, Williams M, Redmond M, Wood F, McMahon C.

Transfus Med. 2010 Aug 1;20(4):287-9. doi: 10.1111/j.1365-3148.2010.00993.x. Epub 2010 Feb 5. No abstract available.


Differential regulation by ATP versus ADP further links CaMKII aggregation to ischemic conditions.

Vest RS, O'Leary H, Bayer KU.

FEBS Lett. 2009 Nov 19;583(22):3577-81. doi: 10.1016/j.febslet.2009.10.028. Epub 2009 Oct 17.


Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice.

Malinowska M, Wilkinson FL, Bennett W, Langford-Smith KJ, O'Leary HA, Jakobkiewicz-Banecka J, Wynn R, Wraith JE, Wegrzyn G, Bigger BW.

Mol Genet Metab. 2009 Nov;98(3):235-42. doi: 10.1016/j.ymgme.2009.06.013. Epub 2009 Jun 27.


Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications.

Musselman CA, Mansfield RE, Garske AL, Davrazou F, Kwan AH, Oliver SS, O'Leary H, Denu JM, Mackay JP, Kutateladze TG.

Biochem J. 2009 Sep 25;423(2):179-87. doi: 10.1042/BJ20090870.


Elevated cerebral pressure passivity is associated with prematurity-related intracranial hemorrhage.

O'Leary H, Gregas MC, Limperopoulos C, Zaretskaya I, Bassan H, Soul JS, Di Salvo DN, du Plessis AJ.

Pediatrics. 2009 Jul;124(1):302-9. doi: 10.1542/peds.2008-2004.


Neurofeedback fMRI-mediated learning and consolidation of regional brain activation during motor imagery.

Yoo SS, Lee JH, O'Leary H, Panych LP, Jolesz FA.

Int J Imaging Syst Technol. 2008 Jun 13;18(1):69-78.


The spectrum of peripheral T-cell lymphomas.

O'leary H, Savage KJ.

Curr Opin Hematol. 2009 Jul;16(4):292-8. doi: 10.1097/MOH.0b013e32832b89a9. Review.


Cerebral hemodynamic changes during intensive care of preterm infants.

Limperopoulos C, Gauvreau KK, O'Leary H, Moore M, Bassan H, Eichenwald EC, Soul JS, Ringer SA, Di Salvo DN, du Plessis AJ.

Pediatrics. 2008 Nov;122(5):e1006-13. doi: 10.1542/peds.2008-0768. Epub 2008 Oct 17.

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