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Items: 8

1.

Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer.

Alexander MS, O'Leary BR, Wilkes JG, Gibson AR, Wagner BA, Du J, Sarsour E, Hwang RF, Buettner GR, Cullen JJ.

Radiat Res. 2018 Oct 30. doi: 10.1667/RR15189.1. [Epub ahead of print]

PMID:
30376411
2.

Pharmacological ascorbate reduces radiation-induced normal tissue toxicity and enhances tumor radiosensitization in pancreatic cancer.

Alexander MS, Wilkes JG, Schroeder SR, Buettner GR, Wagner BA, Du J, Gibson-Corely K, O'Leary BR, Spitz DR, Buatti JM, Berg DJ, Bodeker KL, Vollstedt S, Brown HA, Allen BG, Cullen JJ.

Cancer Res. 2018 Sep 25. pii: canres.1680.2018. doi: 10.1158/0008-5472.CAN-18-1680. [Epub ahead of print]

PMID:
30254147
3.

Pharmacological Ascorbate as an Adjuvant for Enhancing Radiation-Chemotherapy Responses in Gastric Adenocarcinoma.

O'Leary BR, Houwen FK, Johnson CL, Allen BG, Mezhir JJ, Berg DJ, Cullen JJ, Spitz DR.

Radiat Res. 2018 May;189(5):456-465. doi: 10.1667/RR14978.1. Epub 2018 Mar 16.

PMID:
29547353
4.

Pharmacologic ascorbate (P-AscH-) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma.

Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ.

Clin Exp Metastasis. 2018 Feb;35(1-2):37-51. doi: 10.1007/s10585-018-9876-z. Epub 2018 Feb 2.

5.

Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells.

Hrabe JE, O'Leary BR, Fath MA, Rodman SN, Button AM, Domann FE, Spitz DR, Mezhir JJ.

Redox Biol. 2015 Aug;5:319-27. doi: 10.1016/j.redox.2015.06.004. Epub 2015 Jun 18.

6.

Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma.

O'Leary BR, Fath MA, Bellizzi AM, Hrabe JE, Button AM, Allen BG, Case AJ, Altekruse S, Wagner BA, Buettner GR, Lynch CF, Hernandez BY, Cozen W, Beardsley RA, Keene J, Henry MD, Domann FE, Spitz DR, Mezhir JJ.

Clin Cancer Res. 2015 Apr 1;21(7):1741-51. doi: 10.1158/1078-0432.CCR-14-1959. Epub 2015 Jan 29.

7.

Order of magnitude smaller limit on the electric dipole moment of the electron.

ACME Collaboration, Baron J, Campbell WC, DeMille D, Doyle JM, Gabrielse G, Gurevich YV, Hess PW, Hutzler NR, Kirilov E, Kozyryev I, O'Leary BR, Panda CD, Parsons MF, Petrik ES, Spaun B, Vutha AC, West AD.

Science. 2014 Jan 17;343(6168):269-72. doi: 10.1126/science.1248213. Epub 2013 Dec 19.

PMID:
24356114
8.

Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase.

Case AJ, Mezhir JJ, O'Leary BR, Hrabe JE, Domann FE.

Redox Rep. 2012;17(6):239-45. doi: 10.1179/1351000212Y.0000000028.

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