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Best matches for O’Hare H[au]:

PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis. Rieck B et al. PLoS Pathog. (2017)

Tuberculosis: feeding the enemy. Garton NJ et al. Chem Biol. (2013)

GarA is an essential regulator of metabolism in Mycobacterium tuberculosis. Ventura M et al. Mol Microbiol. (2013)

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Items: 22


Mycobacterial phosphatase PstP regulates global serine threonine phosphorylation and cell division.

Iswahyudi, Mukamolova GV, Straatman-Iwanowska AA, Allcock N, Ajuh P, Turapov O, O'Hare HM.

Sci Rep. 2019 Jun 6;9(1):8337. doi: 10.1038/s41598-019-44841-9.


Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.

Wagner T, André-Leroux G, Hindie V, Barilone N, Lisa MN, Hoos S, Raynal B, Vulliez-Le Normand B, O'Hare HM, Bellinzoni M, Alzari PM.

Sci Signal. 2019 May 7;12(580). pii: eaav9504. doi: 10.1126/scisignal.aav9504.


An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria.

Bhattacharyya N, Nkumama IN, Newland-Smith Z, Lin LY, Yin W, Cullen RE, Griffiths JS, Jarvis AR, Price MJ, Chong PY, Wallis R, O'Hare HM.

MBio. 2018 Jul 31;9(4). pii: e00931-18. doi: 10.1128/mBio.00931-18.


PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis.

Rieck B, Degiacomi G, Zimmermann M, Cascioferro A, Boldrin F, Lazar-Adler NR, Bottrill AR, le Chevalier F, Frigui W, Bellinzoni M, Lisa MN, Alzari PM, Nguyen L, Brosch R, Sauer U, Manganelli R, O'Hare HM.

PLoS Pathog. 2017 May 17;13(5):e1006399. doi: 10.1371/journal.ppat.1006399. eCollection 2017 May.


Tuberculosis: feeding the enemy.

Garton NJ, O'Hare HM.

Chem Biol. 2013 Aug 22;20(8):971-2. doi: 10.1016/j.chembiol.2013.08.001.


GarA is an essential regulator of metabolism in Mycobacterium tuberculosis.

Ventura M, Rieck B, Boldrin F, Degiacomi G, Bellinzoni M, Barilone N, Alzaidi F, Alzari PM, Manganelli R, O'Hare HM.

Mol Microbiol. 2013 Oct;90(2):356-66. doi: 10.1111/mmi.12368. Epub 2013 Sep 8.


Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.

Bortoluzzi A, Muskett FW, Waters LC, Addis PW, Rieck B, Munder T, Schleier S, Forti F, Ghisotti D, Carr MD, O'Hare HM.

J Biol Chem. 2013 May 17;288(20):14438-50. doi: 10.1074/jbc.M113.459883. Epub 2013 Apr 2.


Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism.

Wagner T, Bellinzoni M, Wehenkel A, O'Hare HM, Alzari PM.

Chem Biol. 2011 Aug 26;18(8):1011-20. doi: 10.1016/j.chembiol.2011.06.004.


An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis.

Nott TJ, Kelly G, Stach L, Li J, Westcott S, Patel D, Hunt DM, Howell S, Buxton RS, O'Hare HM, Smerdon SJ.

Sci Signal. 2009 Mar 24;2(63):ra12. doi: 10.1126/scisignal.2000212.


CB2 selective sulfamoyl benzamides: optimization of the amide functionality.

Goodman AJ, Ajello CW, Worm K, Le Bourdonnec B, Savolainen MA, O'Hare H, Cassel JA, Stabley GJ, Dehaven RN, Labuda CJ, Koblish M, Little PJ, Brogdon BL, Smith SA, Dolle RE.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):309-13. doi: 10.1016/j.bmcl.2008.11.091. Epub 2008 Nov 27.


Regulation of glutamate metabolism by protein kinases in mycobacteria.

O'Hare HM, Durán R, Cerveñansky C, Bellinzoni M, Wehenkel AM, Pritsch O, Obal G, Baumgartner J, Vialaret J, Johnsson K, Alzari PM.

Mol Microbiol. 2008 Dec;70(6):1408-23. doi: 10.1111/j.1365-2958.2008.06489.x. Epub 2008 Oct 17.


A split-protein sensor for studying protein-protein interaction in mycobacteria.

O'Hare H, Juillerat A, Dianisková P, Johnsson K.

J Microbiol Methods. 2008 May;73(2):79-84. doi: 10.1016/j.mimet.2008.02.008. Epub 2008 Feb 21.


Discovery of a series of aminopiperidines as novel iNOS inhibitors.

Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):336-43. Epub 2007 Oct 25.


Chemical probes shed light on protein function.

O'Hare HM, Johnsson K, Gautier A.

Curr Opin Struct Biol. 2007 Aug;17(4):488-94. Epub 2007 Sep 11. Review.


The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.

Sacco E, Covarrubias AS, O'Hare HM, Carroll P, Eynard N, Jones TA, Parish T, Daffé M, Bäckbro K, Quémard A.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14628-33. Epub 2007 Sep 5.


Conversion of hydroxyphenylpyruvate dioxygenases into hydroxymandelate synthases by directed evolution.

O'Hare HM, Huang F, Holding A, Choroba OW, Spencer JB.

FEBS Lett. 2006 Jun 12;580(14):3445-50. Epub 2006 May 15.


Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase.

Baerga-Ortiz A, Popovic B, Siskos AP, O'Hare HM, Spiteller D, Williams MG, Campillo N, Spencer JB, Leadlay PF.

Chem Biol. 2006 Mar;13(3):277-85.


Broad substrate specificity of ketoreductases derived from modular polyketide synthases.

Bali S, O'Hare HM, Weissman KJ.

Chembiochem. 2006 Mar;7(3):478-84.


The laboratory in a droplet.

O'Hare HM, Johnsson K.

Chem Biol. 2005 Dec;12(12):1255-7. Review.


Asymmetric synthesis of alpha-amino allyl, benzyl, and propargyl silanes by metalation and rearrangement.

Sieburth SM, O'Hare HK, Xu J, Chen Y, Liu G.

Org Lett. 2003 May 29;5(11):1859-61.


The 2001 foot and mouth disease epidemic in the United Kingdom: animal welfare perspectives.

Crispin SM, Roger PA, O'Hare H, Binns SH.

Rev Sci Tech. 2002 Dec;21(3):877-83. Review.

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