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Items: 25

1.

Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells.

O'Connor RS, Milone MC.

Methods Mol Biol. 2020;2097:83-90. doi: 10.1007/978-1-0716-0203-4_5.

PMID:
31776920
2.

Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene.

Sellmyer MA, Richman SA, Lohith K, Hou C, Weng CC, Mach RH, O'Connor RS, Milone MC, Farwell MD.

Mol Ther. 2020 Jan 8;28(1):42-51. doi: 10.1016/j.ymthe.2019.10.007. Epub 2019 Oct 15.

PMID:
31668558
3.

A validated workflow for rapid taxonomic assignment and monitoring of a national fauna of bees (Apiformes) using high throughput DNA barcoding.

Creedy TJ, Norman H, Tang CQ, Qing Chin K, Andujar C, Arribas P, O'Connor RS, Carvell C, Notton DG, Vogler AP.

Mol Ecol Resour. 2020 Jan;20(1):40-53. doi: 10.1111/1755-0998.13056. Epub 2019 Oct 8.

PMID:
31290224
4.

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal.

Liu M, O'Connor RS, Trefely S, Graham K, Snyder NW, Beatty GL.

Nat Immunol. 2019 Jan 21;20(3):265-275. doi: 10.1038/s41590-018-0292-y.

5.

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells.

Ghassemi S, Nunez-Cruz S, O'Connor RS, Fraietta JA, Patel PR, Scholler J, Barrett DM, Lundh SM, Davis MM, Bedoya F, Zhang C, Leferovich J, Lacey SF, Levine BL, Grupp SA, June CH, Melenhorst JJ, Milone MC.

Cancer Immunol Res. 2018 Sep;6(9):1100-1109. doi: 10.1158/2326-6066.CIR-17-0405. Epub 2018 Jul 20.

6.

Avian thermoregulation in the heat: is evaporative cooling more economical in nocturnal birds?

O'Connor RS, Smit B, Talbot WA, Gerson AR, Brigham RM, Wolf BO, McKechnie AE.

J Exp Biol. 2018 Sep 6;221(Pt 17). pii: jeb181420. doi: 10.1242/jeb.181420.

7.

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.

Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ.

Nat Med. 2018 May;24(5):563-571. doi: 10.1038/s41591-018-0010-1. Epub 2018 Apr 30.

8.

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations.

O'Connor RS, Guo L, Ghassemi S, Snyder NW, Worth AJ, Weng L, Kam Y, Philipson B, Trefely S, Nunez-Cruz S, Blair IA, June CH, Milone MC.

Sci Rep. 2018 Apr 19;8(1):6289. doi: 10.1038/s41598-018-24676-6.

9.

CAR T cell immunotherapy for human cancer.

June CH, O'Connor RS, Kawalekar OU, Ghassemi S, Milone MC.

Science. 2018 Mar 23;359(6382):1361-1365. doi: 10.1126/science.aar6711. Review.

PMID:
29567707
10.

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines.

Hippen KL, O'Connor RS, Lemire AM, Saha A, Hanse EA, Tennis NC, Merkel SC, Kelekar A, Riley JL, Levine BL, June CH, Turka LA, Kean LS, MacMillan ML, Miller JS, Wagner JE, Munn DH, Blazar BR.

Am J Transplant. 2017 Dec;17(12):3098-3113. doi: 10.1111/ajt.14338. Epub 2017 Jun 14.

11.

Improving T Cell Expansion with a Soft Touch.

Lambert LH, Goebrecht GK, De Leo SE, O'Connor RS, Nunez-Cruz S, Li TD, Yuan J, Milone MC, Kam LC.

Nano Lett. 2017 Feb 8;17(2):821-826. doi: 10.1021/acs.nanolett.6b04071. Epub 2017 Jan 30.

12.

Avian thermoregulation in the heat: efficient evaporative cooling in two southern African nightjars.

O'Connor RS, Wolf BO, Brigham RM, McKechnie AE.

J Comp Physiol B. 2017 Apr;187(3):477-491. doi: 10.1007/s00360-016-1047-4. Epub 2016 Nov 3.

PMID:
27812726
13.

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR.

J Clin Invest. 2016 Jul 1;126(7):2642-60. doi: 10.1172/JCI85796. Epub 2016 Jun 13.

14.

High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography.

Hu J, Gondarenko AA, Dang AP, Bashour KT, O'Connor RS, Lee S, Liapis A, Ghassemi S, Milone MC, Sheetz MP, Dustin ML, Kam LC, Hone JC.

Nano Lett. 2016 Apr 13;16(4):2198-204. doi: 10.1021/acs.nanolett.5b04364. Epub 2016 Mar 23.

15.

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.

Kawalekar OU, O'Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD Jr, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH.

Immunity. 2016 Feb 16;44(2):380-90. doi: 10.1016/j.immuni.2016.01.021. Erratum in: Immunity. 2016 Mar 15;44(3):712. Snyder, Nathaniel [corrected to Snyder, Nathaniel W]; Blair, Ian [corrected to Blair, Ian A]. Erratum in: Immunity. 2016 Mar 15;44(3):712.

16.

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.

Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CG, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV.

J Clin Invest. 2015 Jun;125(6):2293-306. doi: 10.1172/JCI75836. Epub 2015 Apr 27.

17.

Accounting for habitat when considering climate: has the niche of the Adonis blue butterfly changed in the UK?

O'Connor RS, Hails RS, Thomas JA.

Oecologia. 2014 Apr;174(4):1463-72. doi: 10.1007/s00442-013-2850-1. Epub 2014 Jan 11.

PMID:
24414235
18.

Substrate rigidity regulates human T cell activation and proliferation.

O'Connor RS, Hao X, Shen K, Bashour K, Akimova T, Hancock WW, Kam LC, Milone MC.

J Immunol. 2012 Aug 1;189(3):1330-9. doi: 10.4049/jimmunol.1102757. Epub 2012 Jun 25.

19.

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation.

Babich A, Li S, O'Connor RS, Milone MC, Freedman BD, Burkhardt JK.

J Cell Biol. 2012 Jun 11;197(6):775-87. doi: 10.1083/jcb.201201018. Epub 2012 Jun 4.

20.

Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group.

Reichek JL, Duan F, Smith LM, Gustafson DM, O'Connor RS, Zhang C, Dunlevy MJ, Gastier-Foster JM, Barr FG.

Clin Cancer Res. 2011 Mar 15;17(6):1463-73. doi: 10.1158/1078-0432.CCR-10-0091. Epub 2011 Jan 10.

21.

Phosphocreatine as an energy source for actin cytoskeletal rearrangements during myoblast fusion.

O'Connor RS, Steeds CM, Wiseman RW, Pavlath GK.

J Physiol. 2008 Jun 15;586(12):2841-53. doi: 10.1113/jphysiol.2008.151027. Epub 2008 Apr 17.

22.

Last Word on Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy.

O'Connor RS, Pavlath GK, McCarthy JJ, Esser KA.

J Appl Physiol (1985). 2007 Sep;103(3):1107. No abstract available.

23.

Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy.

O'Connor RS, Pavlath GK.

J Appl Physiol (1985). 2007 Sep;103(3):1099-100. Epub 2007 Feb 8. No abstract available.

24.

A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis.

O'Connor RS, Mills ST, Jones KA, Ho SN, Pavlath GK.

J Cell Sci. 2007 Jan 1;120(Pt 1):149-59. Epub 2006 Dec 12.

25.

Sca-1 negatively regulates proliferation and differentiation of muscle cells.

Mitchell PO, Mills T, O'Connor RS, Kline ER, Graubert T, Dzierzak E, Pavlath GK.

Dev Biol. 2005 Jul 1;283(1):240-52. Erratum in: Dev Biol. 2006 Dec 15;300(2):785. Kline, Erik R [added].

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