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In vitro Infection of Primary Human Monocytes with HIV-1.

O'Connell P, Zheng YH, Amalfitano A, Aldhamen YA.

Bio Protoc. 2019 Jul 5;9(13). doi: 10.21769/bioprotoc.3289.


Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: the 2019 Expert Consensus From the Transplantion Society Working Group.

Schinstock CA, Mannon RB, Budde K, Chong AS, Haas M, Knechtle S, Lefaucheur C, Montgomery RA, Nickerson P, Tullius SG, Ahn C, Askar M, Crespo M, Chadban SJ, Feng S, Jordan SC, Man K, Mengel M, Morris RE, O'Doherty I, Ozdemir BH, Seron D, Tambur AR, Tanabe K, Taupin JL, O'Connell PJ.

Transplantation. 2020 Jan 8. doi: 10.1097/TP.0000000000003095. [Epub ahead of print]


Moral cognition, the missing link between psychotic symptoms and acts of violence: a cross-sectional national forensic cohort study.

O'Reilly K, O'Connell P, O'Sullivan D, Corvin A, Sheerin J, O'Flynn P, Donohoe G, McCarthy H, Ambrosh D, O'Donnell M, Ryan A, Kennedy HG.

BMC Psychiatry. 2019 Dec 19;19(1):408. doi: 10.1186/s12888-019-2372-4.


Establishing a national program of islet transplantation in Australia.

O'Connell PJ, Kay TWH.

CellR4 Repair Replace Regen Reprogram. 2019;7. pii: e2797. doi: 10.32113/cellr4_201911_2797. Epub 2019 Nov 21. No abstract available.


Neurosciences, Rehabilitation and Vision Strategic Clinical Network: Improving how Albertans see, think and live.

McKenzie N, O'Connell P, Ho C; Neurosciences, Rehabilitation and Vision Strategic Clinical Network.

CMAJ. 2019 Dec 4;191(Suppl):S49-S51. doi: 10.1503/cmaj.190597. No abstract available.


Diabetes, Obesity and Nutrition Strategic Clinical Network: Capitalizing on interdisciplinary networked thinking.

Sargious PM, O'Connell P, Chan CB; Diabetes, Obesity and Network Nutrition Strategic Clinical.

CMAJ. 2019 Dec 4;191(Suppl):S17-S18. doi: 10.1503/cmaj.190564. No abstract available.


SLAM Family Receptor Signaling in Viral Infections: HIV and Beyond.

O'Connell P, Amalfitano A, Aldhamen YA.

Vaccines (Basel). 2019 Nov 16;7(4). pii: E184. doi: 10.3390/vaccines7040184. Review.


The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis.

Earley H, Lennon G, Balfe Á, Coffey JC, Winter DC, O'Connell PR.

Sci Rep. 2019 Oct 30;9(1):15683. doi: 10.1038/s41598-019-51878-3.


Rectovaginal fistula repair - a video vignette.

Climent M, McCawley N, Hanly AM, O'Connell PR.

Colorectal Dis. 2019 Oct 22. doi: 10.1111/codi.14882. [Epub ahead of print] No abstract available.


A20 as an immune tolerance factor can determine islet transplant outcomes.

Zammit NW, Walters SN, Seeberger KL, O'Connell PJ, Korbutt GS, Grey ST.

JCI Insight. 2019 Nov 1;4(21). pii: 131028. doi: 10.1172/jci.insight.131028.


The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes.

Mah PT, O'Connell P, Focaroli S, Lundy R, O'Mahony TF, Hastedt JE, Gitlin I, Oscarson S, Fahy JV, Healy AM.

Eur J Pharm Biopharm. 2019 Nov;144:139-153. doi: 10.1016/j.ejpb.2019.09.014. Epub 2019 Sep 16.


Effect of Delays in Civil Commitment Hearings on Outcomes Among Psychiatric Inpatients.

Kious BM, Dobias L, O'Connell PH.

J Am Acad Psychiatry Law. 2019 Dec;47(4):467-475. doi: 10.29158/JAAPL.003868-19. Epub 2019 Sep 16.


The projection of anorectal afferents to cortex of the rat: Comparison of two methods of cortical mapping.

Turner K, Pickering M, O'Connell PR, Jones JFX.

Neurogastroenterol Motil. 2019 Dec;31(12):e13709. doi: 10.1111/nmo.13709. Epub 2019 Aug 27.


The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function.

Carrington EV, Heinrich H, Knowles CH, Fox M, Rao S, Altomare DF, Bharucha AE, Burgell R, Chey WD, Chiarioni G, Dinning P, Emmanuel A, Farouk R, Felt-Bersma RJF, Jung KW, Lembo A, Malcolm A, Mittal RK, Mion F, Myung SJ, O'Connell PR, Pehl C, Remes-Troche JM, Reveille RM, Vaizey CJ, Vitton V, Whitehead WE, Wong RK, Scott SM; All members of the International Anorectal Physiology Working Group.

Neurogastroenterol Motil. 2020 Jan;32(1):e13679. doi: 10.1111/nmo.13679. Epub 2019 Aug 12.


Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.

Ghimire K, Chiba T, Minhas N, Meijles DN, Lu B, O'Connell P, Rogers NM.

FASEB J. 2019 Oct;33(10):11528-11540. doi: 10.1096/fj.201900583R. Epub 2019 Aug 1.


The long noncoding RNA MALAT1 predicts human pancreatic islet isolation quality.

Wong WK, Jiang G, Sørensen AE, Chew YV, Lee-Maynard C, Liuwantara D, Williams L, O'Connell PJ, Dalgaard LT, Ma RC, Hawthorne WJ, Joglekar MV, Hardikar AA.

JCI Insight. 2019 Jul 30;5. pii: 129299. doi: 10.1172/jci.insight.129299.


A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection.

Zhang W, Yi Z, Keung KL, Shang H, Wei C, Cravedi P, Sun Z, Xi C, Woytovich C, Farouk S, Huang W, Banu K, Gallon L, Magee CN, Najafian N, Samaniego M, Djamali A, Alexander SI, Rosales IA, Smith RN, Xiang J, Lerut E, Kuypers D, Naesens M, O'Connell PJ, Colvin R, Menon MC, Murphy B.

J Am Soc Nephrol. 2019 Aug;30(8):1481-1494. doi: 10.1681/ASN.2018111098. Epub 2019 Jul 5.


Minimally invasive approaches to the management of anastomotic leakage following restorative rectal cancer resection.

Creavin B, Ryan ÉJ, Kelly ME, Moynihan A, Redmond CE, Ahern D, Kennelly R, Hanly A, Martin ST, O'Connell PR, Brophy DP, Winter DC.

Colorectal Dis. 2019 Dec;21(12):1364-1371. doi: 10.1111/codi.14742. Epub 2019 Jul 17.


Meta-analysis of the effect of extending the interval after long-course chemoradiotherapy before surgery in locally advanced rectal cancer.

Ryan ÉJ, O'Sullivan DP, Kelly ME, Syed AZ, Neary PC, O'Connell PR, Kavanagh DO, Winter DC, O'Riordan JM.

Br J Surg. 2019 Sep;106(10):1298-1310. doi: 10.1002/bjs.11220. Epub 2019 Jun 19. Review.


Pretransplant transcriptomic signature in peripheral blood predicts early acute rejection.

Zhang W, Yi Z, Wei C, Keung KL, Sun Z, Xi C, Woytovich C, Farouk S, Gallon L, Menon MC, Magee C, Najafian N, Samaniego MD, Djamali A, Alexander SI, Rosales IA, Smith RN, O'Connell PJ, Colvin R, Cravedi P, Murphy B.

JCI Insight. 2019 Jun 6;4(11). pii: 127543. doi: 10.1172/jci.insight.127543. eCollection 2019 Jun 6.


β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes.

Lalwani A, Warren J, Liuwantara D, Hawthorne WJ, O'Connell PJ, Gonzalez FJ, Stokes RA, Chen J, Laybutt DR, Craig ME, Swarbrick MM, King C, Gunton JE.

Cell Rep. 2019 May 21;27(8):2370-2384.e6. doi: 10.1016/j.celrep.2019.04.086.


Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients.

Jimenez Vera E, Chew YV, Nicholson L, Burns H, Anderson P, Chen HT, Williams L, Keung K, Zanjani NT, Dervish S, Patrick E, Wang XM, Yi S, Hawthorne W, Alexander S, O'Connell PJ, Hu M.

PLoS One. 2019 May 22;14(5):e0217163. doi: 10.1371/journal.pone.0217163. eCollection 2019.


Increasing access to integrated ESKD care as part of universal health coverage.

Harris DCH, Davies SJ, Finkelstein FO, Jha V, Donner JA, Abraham G, Bello AK, Caskey FJ, Garcia GG, Harden P, Hemmelgarn B, Johnson DW, Levin NW, Luyckx VA, Martin DE, McCulloch MI, Moosa MR, O'Connell PJ, Okpechi IG, Pecoits Filho R, Shah KD, Sola L, Swanepoel C, Tonelli M, Twahir A, van Biesen W, Varghese C, Yang CW, Zuniga C; Working Groups of the International Society of Nephrology’s 2nd Global Kidney Health Summit.

Kidney Int. 2019 Apr;95(4S):S1-S33. doi: 10.1016/j.kint.2018.12.005. Review.


The psychiatric management of prisoners on hunger strike: developing a management algorithm using the Delphi technique.

Gulati G, Kelly BD, O'Neill C, O'Connell P, Linehan S, Spain E, Meagher D, Dunne CP.

Int J Prison Health. 2019 Mar 11;15(1):66-75. doi: 10.1108/IJPH-06-2017-0030. Epub 2019 Feb 20.


The projection of anorectal afferents to spinal cord and effect of sacral neuromodulation on dorsal horn neurons which receive such input in the rat.

Turner K, O'Connell PR, Jones JFX.

Neurogastroenterol Motil. 2019 Apr;31(4):e13536. doi: 10.1111/nmo.13536. Epub 2019 Jan 22.


A randomized controlled trial of cognitive remediation for a national cohort of forensic patients with schizophrenia or schizoaffective disorder.

O'Reilly K, Donohoe G, O'Sullivan D, Coyle C, Corvin A, O'Flynn P, O'Donnell M, Galligan T, O'Connell P, Kennedy HG.

BMC Psychiatry. 2019 Jan 15;19(1):27. doi: 10.1186/s12888-019-2018-6.


Periostin levels in children without respiratory disease.

O'Connell P, Gaston B, Bonfield T, Grabski T, Fletcher D, Shein SL.

Pediatr Pulmonol. 2019 Feb;54(2):200-204. doi: 10.1002/ppul.24206. Epub 2018 Dec 11.


Mortality in People With Type 1 Diabetes, Severe Hypoglycemia, and Impaired Awareness of Hypoglycemia Referred for Islet Transplantation.

Lee MH, Ward GM, MacIsaac RJ, Howe K, Holmes-Walker DJ, Anderson P, Radford T, Coates PT, Kay TW, O'Connell PJ, Goodman DJ.

Transplant Direct. 2018 Oct 23;4(11):e401. doi: 10.1097/TXD.0000000000000841. eCollection 2018 Nov. No abstract available.


SLAMF7 Is a Critical Negative Regulator of IFN-α-Mediated CXCL10 Production in Chronic HIV Infection.

O'Connell P, Pepelyayeva Y, Blake MK, Hyslop S, Crawford RB, Rizzo MD, Pereira-Hicks C, Godbehere S, Dale L, Gulick P, Kaminski NE, Amalfitano A, Aldhamen YA.

J Immunol. 2019 Jan 1;202(1):228-238. doi: 10.4049/jimmunol.1800847. Epub 2018 Dec 10.


The Association of Coloproctology of Great Britain and Ireland consensus guidelines in surgery for inflammatory bowel disease.

Brown SR, Fearnhead NS, Faiz OD, Abercrombie JF, Acheson AG, Arnott RG, Clark SK, Clifford S, Davies RJ, Davies MM, Douie WJP, Dunlop MG, Epstein JC, Evans MD, George BD, Guy RJ, Hargest R, Hawthorne AB, Hill J, Hughes GW, Limdi JK, Maxwell-Armstrong CA, O'Connell PR, Pinkney TD, Pipe J, Sagar PM, Singh B, Soop M, Terry H, Torkington J, Verjee A, Walsh CJ, Warusavitarne JH, Williams AB, Williams GL, Wilson RG; ACPGBI IBD Surgery Consensus Collaboration.

Colorectal Dis. 2018 Dec;20 Suppl 8:3-117. doi: 10.1111/codi.14448.


Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair-deficient colorectal cancer.

Ryan ÉJ, Creavin B, Khaw YL, Kelly ME, Mohan HM, Geraghty R, Ryan EJ, Kennelly R, Hanly A, Martin ST, Fennelly D, McDermott R, Gibbons D, O'Connell PR, Sheahan K, Winter DC.

BJS Open. 2018 Jul 24;2(6):456-463. doi: 10.1002/bjs5.91. eCollection 2018 Dec.


Epigenetic and Transcriptome Profiling Identifies a Population of Visceral Adipose-Derived Progenitor Cells with the Potential to Differentiate into an Endocrine Pancreatic Lineage.

Williams MD, Joglekar MV, Satoor SN, Wong W, Keramidaris E, Rixon A, O'Connell P, Hawthorne WJ, Mitchell GM, Hardikar AA.

Cell Transplant. 2019 Jan;28(1):89-104. doi: 10.1177/0963689718808472. Epub 2018 Oct 30.


Everolimus and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Registry-based 10-year Follow-up of 5 Randomized Trials.

Ying T, Wong G, Lim WH, Clayton P, Kanellis J, Pilmore H, Campbell S, O'Connell PJ, Russ G, Chadban S.

Transplantation. 2019 Aug;103(8):1705-1713. doi: 10.1097/TP.0000000000002499.


SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts.

Wei C, Banu K, Garzon F, Basgen JM, Philippe N, Yi Z, Liu R, Choudhuri J, Fribourg M, Liu T, Cumpelik A, Wong J, Khan M, Das B, Keung K, Salem F, Campbell KN, Kaufman L, Cravedi P, Zhang W, O'Connell PJ, He JC, Murphy B, Menon MC.

J Am Soc Nephrol. 2018 Nov;29(11):2641-2657. doi: 10.1681/ASN.2018060573. Epub 2018 Oct 19.


Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial.

Busque S, Vincenti FG, Tedesco Silva H, O'Connell PJ, Yoshida A, Friedewald JJ, Steinberg SM, Budde K, Broeders EN, Kim YS, Hahn CM, Li H, Chan G.

Transplant Direct. 2018 Aug 8;4(9):e380. doi: 10.1097/TXD.0000000000000819. eCollection 2018 Sep.


Engineering of pharmaceutical cocrystals in an excipient matrix: Spray drying versus hot melt extrusion.

Walsh D, Serrano DR, Worku ZA, Madi AM, O'Connell P, Twamley B, Healy AM.

Int J Pharm. 2018 Nov 15;551(1-2):241-256. doi: 10.1016/j.ijpharm.2018.09.029. Epub 2018 Sep 14.


Prospective observational cohort study of 'treatment as usual' over four years for patients with schizophrenia in a national forensic hospital.

Richter MS, O'Reilly K, O'Sullivan D, O'Flynn P, Corvin A, Donohoe G, Coyle C, Davoren M, Higgins C, Byrne O, Nutley T, Nulty A, Sharma K, O'Connell P, Kennedy HG.

BMC Psychiatry. 2018 Sep 8;18(1):289. doi: 10.1186/s12888-018-1862-0.


ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis.

Pepelyayeva Y, Rastall DPW, Aldhamen YA, O'Connell P, Raehtz S, Alyaqoub FS, Blake MK, Raedy AM, Angarita AM, Abbas AM, Pereira-Hicks CN, Roosa SG, McCabe L, Amalfitano A.

Sci Rep. 2018 Aug 20;8(1):12464. doi: 10.1038/s41598-018-30159-5.


6th International Consultation on Incontinence. Recommendations of the International Scientific Committee: EVALUATION AND TREATMENT OF URINARY INCONTINENCE, PELVIC ORGAN PROLAPSE AND FAECAL INCONTINENCE.

Abrams P, Andersson KE, Apostolidis A, Birder L, Bliss D, Brubaker L, Cardozo L, Castro-Diaz D, O'Connell PR, Cottenden A, Cotterill N, de Ridder D, Dmochowski R, Dumoulin C, Fader M, Fry C, Goldman H, Hanno P, Homma Y, Khullar V, Maher C, Milsom I, Newman D, Nijman RJM, Rademakers K, Robinson D, Rosier P, Rovner E, Salvatore S, Takeda M, Wagg A, Wagner T, Wein A; members of the committees.

Neurourol Urodyn. 2018 Sep;37(7):2271-2272. doi: 10.1002/nau.23551. Epub 2018 Aug 14. No abstract available.


Efficacy and mechanism of sub-sensory sacral (optimised) neuromodulation in adults with faecal incontinence: study protocol for a randomised controlled trial.

McAlees E, Vollebregt PF, Stevens N, Dudding TC, Emmanuel AV, Furlong PL, Hamdy S, Hooper RL, Jones JFX, Norton C, O'Connell PR, Scott SM, Knowles CH.

Trials. 2018 Jun 26;19(1):336. doi: 10.1186/s13063-018-2689-1.


De novo or early conversion to everolimus and long-term cancer outcomes in kidney transplant recipients: A trial-based linkage study.

Ying T, Wong G, Lim W, Kanellis J, Pilmore H, Campbell S, Masterson R, Walker R, O'Connell P, Russ G, Chadban S.

Am J Transplant. 2018 Dec;18(12):2977-2986. doi: 10.1111/ajt.14948. Epub 2018 Jun 27.


IntAct: intra-operative fluorescence angiography to prevent anastomotic leak in rectal cancer surgery: a randomized controlled trial.

Armstrong G, Croft J, Corrigan N, Brown JM, Goh V, Quirke P, Hulme C, Tolan D, Kirby A, Cahill R, O'Connell PR, Miskovic D, Coleman M, Jayne D.

Colorectal Dis. 2018 Aug;20(8):O226-O234. doi: 10.1111/codi.14257. Epub 2018 Jun 8.


Safety and efficacy of pasireotide in dumping syndrome-results from a phase 2, multicentre study.

Tack J, Aberle J, Arts J, Laville M, Oppert JM, Bender G, Bhoyrul S, McLaughlin T, Yoshikawa T, Vella A, Zhou J, Passos VQ, O'Connell P, Van Beek AP.

Aliment Pharmacol Ther. 2018 Jun;47(12):1661-1672. doi: 10.1111/apt.14664. Epub 2018 Apr 25.


Isolation and gene expression profiling of intestinal epithelial cells: crypt isolation by calcium chelation from in vivo samples.

Balfe A, Lennon G, Lavelle A, Docherty NG, Coffey JC, Sheahan K, Winter DC, O'Connell PR.

Clin Exp Gastroenterol. 2018 Jan 12;11:29-37. doi: 10.2147/CEG.S145224. eCollection 2018.


Correction to: Voriconazole-induced periostitis deformans: serial imaging in a patient with ANCA vasculitis.

Cormican S, Adams N, O'Connell P, McErlean A, de Freitas D.

Skeletal Radiol. 2018 Apr;47(4):541. doi: 10.1007/s00256-018-2886-8.


Optimising the in vitro and in vivo performance of oral cocrystal formulations via spray coating.

Serrano DR, Walsh D, O'Connell P, Mugheirbi NA, Worku ZA, Bolas-Fernandez F, Galiana C, Dea-Ayuela MA, Healy AM.

Eur J Pharm Biopharm. 2018 Mar;124:13-27. doi: 10.1016/j.ejpb.2017.11.015. Epub 2017 Dec 22.


The causes, significance and consequences of inflammatory fibrosis in kidney transplantation: The Banff i-IFTA lesion.

Nankivell BJ, Shingde M, Keung KL, Fung CL, Borrows RJ, O'Connell PJ, Chapman JR.

Am J Transplant. 2018 Feb;18(2):364-376. doi: 10.1111/ajt.14609. Epub 2018 Jan 3.


Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer.

Ryan É, Khaw YL, Creavin B, Geraghty R, Ryan EJ, Gibbons D, Hanly A, Martin ST, O'Connell PR, Winter DC, Sheahan K.

Am J Surg Pathol. 2018 Jan;42(1):60-68. doi: 10.1097/PAS.0000000000000931.


Management of Patients Who Receive an Organ Transplant Abroad and Return Home for Follow-up Care: Recommendations From the Declaration of Istanbul Custodian Group.

Domínguez-Gil B, Danovitch G, Martin DE, López-Fraga M, Van Assche K, Morris ML, Lavee J, Erlich G, Fadhil R, Busic M, Rankin G, Al-Rukhaimi M, OʼConnell P, Chin J, Norman T, Massari P, Kamel R, Delmonico FL; Declaration of Istanbul Custodian Group working group on ethical travel for transplantation.

Transplantation. 2018 Jan;102(1):e2-e9. doi: 10.1097/TP.0000000000001963.


A European survey of bowel preparation in colorectal surgery.

Devane LA, Proud D, O'Connell PR, Panis Y.

Colorectal Dis. 2017 Nov;19(11):O402-O406. doi: 10.1111/codi.13905.


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