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Items: 44

1.

Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics.

Liu QR, Huang NS, Qu H, O'Connell JF, Gonzalez-Mariscal I, Santa-Cruz-Calvo S, Doyle ME, Xi ZX, Wang Y, Onaivi ES, Egan JM.

Acta Pharmacol Sin. 2018 Sep 10. doi: 10.1038/s41401-018-0152-1. [Epub ahead of print]

PMID:
30202012
2.

When did Homo sapiens first reach Southeast Asia and Sahul?

O'Connell JF, Allen J, Williams MAJ, Williams AN, Turney CSM, Spooner NA, Kamminga J, Brown G, Cooper A.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):8482-8490. doi: 10.1073/pnas.1808385115. Epub 2018 Aug 6.

PMID:
30082377
3.

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets.

González-Mariscal I, Montoro RA, Doyle ME, Liu QR, Rouse M, O'Connell JF, Santa-Cruz Calvo S, Krzysik-Walker SM, Ghosh S, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Chia CW, Ghosh P, Egan JM.

Diabetologia. 2018 Jun;61(6):1470-1483. doi: 10.1007/s00125-018-4576-4. Epub 2018 Mar 1.

PMID:
29497784
4.

NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.

Hou Y, Lautrup S, Cordonnier S, Wang Y, Croteau DL, Zavala E, Zhang Y, Moritoh K, O'Connell JF, Baptiste BA, Stevnsner TV, Mattson MP, Bohr VA.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1876-E1885. doi: 10.1073/pnas.1718819115. Epub 2018 Feb 5.

5.

Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism.

González-Mariscal I, Krzysik-Walker SM, Doyle ME, Liu QR, Cimbro R, Santa-Cruz Calvo S, Ghosh S, Cieśla Ł, Moaddel R, Carlson OD, Witek RP, O'Connell JF, Egan JM.

Sci Rep. 2016 Sep 19;6:33302. doi: 10.1038/srep33302.

6.

The pyrophilic primate hypothesis.

Parker CH, Keefe ER, Herzog NM, O'connell JF, Hawkes K.

Evol Anthropol. 2016 Mar-Apr;25(2):54-63. doi: 10.1002/evan.21475.

PMID:
27061034
7.

More lessons from the Hadza about men's work.

Hawkes K, O'Connell JF, Jones NG.

Hum Nat. 2014 Dec;25(4):596-619. doi: 10.1007/s12110-014-9212-5.

PMID:
25253038
8.

Early Americans: respecting ancestors.

Grayson DK, Meltzer DJ, Buikstra JE, Flannery KV, Fowler CS, Marcus J, O'Connell JF, Piperno DR, Sabloff JA, Smith BD, Thomas DH, Willerslev E, Zeder MA.

Science. 2014 Jul 25;345(6195):390. doi: 10.1126/science.345.6195.390-b. Epub 2014 Jul 24. No abstract available.

PMID:
25061197
9.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

10.

How old is human longevity?

Hawkes K, O'Connell JF.

J Hum Evol. 2005 Nov;49(5):650-3; discussion 654-9. Epub 2005 Oct 14. No abstract available.

PMID:
16226787
11.

Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.

Howe AY, Bloom J, Baldick CJ, Benetatos CA, Cheng H, Christensen JS, Chunduru SK, Coburn GA, Feld B, Gopalsamy A, Gorczyca WP, Herrmann S, Johann S, Jiang X, Kimberland ML, Krisnamurthy G, Olson M, Orlowski M, Swanberg S, Thompson I, Thorn M, Del Vecchio A, Young DC, van Zeijl M, Ellingboe JW, Upeslacis J, Collett M, Mansour TS, O'Connell JF.

Antimicrob Agents Chemother. 2004 Dec;48(12):4813-21.

12.

Male strategies and Plio-Pleistocene archaeology.

O'Connell JF, Hawkes K, Lupo KD, Blurton Jones NG.

J Hum Evol. 2002 Dec;43(6):831-72. Review.

PMID:
12473486
13.

Antiquity of postreproductive life: are there modern impacts on hunter-gatherer postreproductive life spans?

Blurton Jones NG, Hawkes K, O'Connell JF.

Am J Hum Biol. 2002 Mar-Apr;14(2):184-205.

PMID:
11891933
14.

RFI-641, a potent respiratory syncytial virus inhibitor.

Huntley CC, Weiss WJ, Gazumyan A, Buklan A, Feld B, Hu W, Jones TR, Murphy T, Nikitenko AA, O'Hara B, Prince G, Quartuccio S, Raifeld YE, Wyde P, O'Connell JF.

Antimicrob Agents Chemother. 2002 Mar;46(3):841-7.

15.

Hadza meat sharing.

Hawkes K, O'Connell JF, Blurton Jones NG.

Evol Hum Behav. 2001 Mar;22(2):113-142.

PMID:
11282309
16.

Genetics, archaeology, and holocene hunter-gatherers.

O'Connell JF.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10562-3. Review. No abstract available.

17.

Peptide aldehyde inhibitors of bacterial peptide deformylases.

Durand DJ, Gordon Green B, O'Connell JF, Grant SK.

Arch Biochem Biophys. 1999 Jul 15;367(2):297-302.

PMID:
10395747
19.

Grandmothering and the evolution of homo erectus.

O'connell JF, Hawkes K, Blurton Jones NG.

J Hum Evol. 1999 May;36(5):461-85.

PMID:
10222165
20.

Predictable deuteration of recombinant proteins expressed in Escherichia coli.

Leiting B, Marsilio F, O'Connell JF.

Anal Biochem. 1998 Dec 15;265(2):351-5.

PMID:
9882413
21.

Treatment of human enterovirus infections.

Rotbart HA, O'Connell JF, McKinlay MA.

Antiviral Res. 1998 Apr;38(1):1-14. Review. No abstract available.

PMID:
9613999
22.

Grandmothering, menopause, and the evolution of human life histories.

Hawkes K, O'Connell JF, Jones NG, Alvarez H, Charnov EL.

Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1336-9.

23.

SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2.

Albin R, Chase R, Risano C, Lieberman M, Ferrari E, Skelton A, Buontempo P, Cox S, DeMartino J, Wright-Minogue J, Jirau-Lucca G, Kelly J, Afonso A, Kwong AD, Rozhon EJ, O'Connell JF.

Antiviral Res. 1997 Aug;35(3):139-46.

PMID:
9298753
24.

SCH 48973: a potent, broad-spectrum, antienterovirus compound.

Buontempo PJ, Cox S, Wright-Minogue J, DeMartino JL, Skelton AM, Ferrari E, Albin R, Rozhon EJ, Girijavallabhan V, Modlin JF, O'Connell JF.

Antimicrob Agents Chemother. 1997 Jun;41(6):1220-5.

25.

Diagnosis of enterovirus infection by polymerase chain reaction of multiple specimen types.

Rotbart HA, Ahmed A, Hickey S, Dagan R, McCracken GH Jr, Whitley RJ, Modlin JF, Cascino M, O'Connell JF, Menegus MA, Blum D.

Pediatr Infect Dis J. 1997 Apr;16(4):409-11. No abstract available.

PMID:
9109145
26.

The behavioral ecology of modern hunter-gatherers, and human evolution.

Hawkes K, O'Connell JF, Rogers L.

Trends Ecol Evol. 1997 Jan;12(1):29-32.

PMID:
21237958
27.

Antipicornavirus activity of SCH 47802 and analogs: in vitro and in vivo studies.

Cox S, Buontempo PJ, Wright-Minogue J, DeMartino JL, Skelton AM, Ferrari E, Schwartz J, Rozhon EJ, Linn CC, Girijavallabhan V, O'Connell JF.

Antiviral Res. 1996 Oct;32(2):71-9.

PMID:
8891166
28.

Comparison of the structure of human recombinant short form stromelysin by multidimensional heteronuclear NMR and X-ray crystallography.

Gooley PR, O'Connell JF, Marcy AI, Cuca GC, Axel MG, Caldwell CG, Hagmann WK, Becker JW.

J Biomol NMR. 1996 Jan;7(1):8-28.

PMID:
8720828
29.

The nuclear-magnetic-resonance solution structure of the mutant alpha-amylase inhibitor [R19L] Tendamistat and comparison with wild-type Tendamistat.

O'Connell JF, Bender R, Engels JW, Koller KP, Scharf M, Wüthrich K.

Eur J Biochem. 1994 Mar 15;220(3):763-70.

30.

The NMR structure of the inhibited catalytic domain of human stromelysin-1.

Gooley PR, O'Connell JF, Marcy AI, Cuca GC, Salowe SP, Bush BL, Hermes JD, Esser CK, Hagmann WK, Springer JP, et al.

Nat Struct Biol. 1994 Feb;1(2):111-8.

PMID:
7656014
31.
32.

Demography of the Hadza, an increasing and high density population of Savanna foragers.

Blurton Jones NG, Smith LC, O'Connell JF, Hawkes K, Kamuzora CL.

Am J Phys Anthropol. 1992 Oct;89(2):159-81.

PMID:
1443092
33.

Hunting income patterns among the Hadza: big game, common goods, foraging goals and the evolution of the human diet.

Hawkes K, O'Connell JF, Jones NG.

Philos Trans R Soc Lond B Biol Sci. 1991 Nov 29;334(1270):243-50; discussion 250-1.

PMID:
1685582
34.

Investigations of multistage carcinogenesis: applications of in vitro-in vivo studies.

O'Connell JF, Miller DR, Morris RJ, Patskan GP, Viaje AV, Tacker K, Slaga TJ.

Carcinog Compr Surv. 1989;11:339-48. Review. No abstract available.

PMID:
2493337
35.

Exclusive A-ring linkage for singly attached phycocyanobilins and phycoerythrobilins in phycobiliproteins. Absence of singly D-ring-linked bilins.

Lagarias JC, Klotz AV, Dallas JL, Glazer AN, Bishop JE, O'Connell JF, Rapoport H.

J Biol Chem. 1988 Sep 15;263(26):12977-85.

36.

Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression.

Ostrowski LE, Finch J, Krieg P, Matrisian L, Patskan G, O'Connell JF, Phillips J, Slaga TJ, Breathnach R, Bowden GT.

Mol Carcinog. 1988;1(1):13-9.

PMID:
3151258
38.

Characterization of an inbred strain of the SENCAR mouse that is highly sensitive to phorbol esters.

Fischer SM, O'Connell JF, Conti CJ, Tacker KC, Fries JW, Patrick KE, Adams LM, Slaga TJ.

Carcinogenesis. 1987 Mar;8(3):421-4.

PMID:
3545526
39.

Synthesis and radiolabeling of heterocyclic food mutagens.

Rapoport H, Waterhouse AL, Thompson CM, O'Connell JF.

Environ Health Perspect. 1986 Aug;67:41-5.

40.

Enhanced malignant progression of mouse skin tumors by the free-radical generator benzoyl peroxide.

O'Connell JF, Klein-Szanto AJ, DiGiovanni DM, Fries JW, Slaga TJ.

Cancer Res. 1986 Jun;46(6):2863-5.

41.

Malignant progression of mouse skin papillomas treated with ethylnitrosourea, N-methyl-N'-nitro-N-nitrosoguanidine, or 12-O-tetradecanoylphorbol-13-acetate.

O'Connell JF, Klein-Szanto AJ, Digiovanni DM, Fries JW, Slaga TJ.

Cancer Lett. 1986 Mar;30(3):269-74.

PMID:
2870794
42.

Inhibitory effect of toluene on tumor promotion in mouse skin.

Weiss HS, O'Connell JF, Hakaim AG, Jacoby WT.

Proc Soc Exp Biol Med. 1986 Feb;181(2):199-204.

PMID:
3080753
43.

Acceleration of skin tumorigenesis in mice by submandibular and sublingual gland excision.

O'Connell JF, Weiss HS, Pitt JF, Miller RE, Graff DE.

Carcinogenesis. 1983 Sep;4(9):1197-9.

PMID:
6309426
44.

Australian prehistory: new aspects of antiquity.

White JP, O'connell JF.

Science. 1979 Jan 5;203(4375):21-8.

PMID:
17840495

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