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Items: 17


The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration.

Lu W, Gómez NM, Lim JC, Guha S, O'Brien-Jenkins A, Coffey EE, Campagno KE, McCaughey SA, Laties AM, Carlsson LG, Mitchell CH.

Front Pharmacol. 2018 Apr 19;9:242. doi: 10.3389/fphar.2018.00242. eCollection 2018.


Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor.

Guha S, Baltazar GC, Coffey EE, Tu LA, Lim JC, Beckel JM, Patel S, Eysteinsson T, Lu W, O'Brien-Jenkins A, Laties AM, Mitchell CH.

FASEB J. 2013 Nov;27(11):4500-9. doi: 10.1096/fj.13-236166. Epub 2013 Aug 20.


Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment.

Yang N, Huang J, Greshock J, Liang S, Barchetti A, Hasegawa K, Kim S, Giannakakis A, Li C, O'Brien-Jenkins A, Katsaros D, Bützow R, Coukos G, Zhang L.

PLoS One. 2008 Mar 12;3(3):e1758. doi: 10.1371/journal.pone.0001758.


Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.

Buckanovich RJ, Facciabene A, Kim S, Benencia F, Sasaroli D, Balint K, Katsaros D, O'Brien-Jenkins A, Gimotty PA, Coukos G.

Nat Med. 2008 Jan;14(1):28-36. Epub 2008 Jan 6.


miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer.

Giannakakis A, Sandaltzopoulos R, Greshock J, Liang S, Huang J, Hasegawa K, Li C, O'Brien-Jenkins A, Katsaros D, Weber BL, Simon C, Coukos G, Zhang L.

Cancer Biol Ther. 2008 Feb;7(2):255-64. Epub 2007 Nov 14.


Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer.

Zhang L, Huang J, Yang N, Greshock J, Liang S, Hasegawa K, Giannakakis A, Poulos N, O'Brien-Jenkins A, Katsaros D, Butzow R, Weber BL, Coukos G.

Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5314-21.


Tumor vascular proteins as biomarkers in ovarian cancer.

Buckanovich RJ, Sasaroli D, O'Brien-Jenkins A, Botbyl J, Hammond R, Katsaros D, Sandaltzopoulos R, Liotta LA, Gimotty PA, Coukos G.

J Clin Oncol. 2007 Mar 1;25(7):852-61.


microRNAs exhibit high frequency genomic alterations in human cancer.

Zhang L, Huang J, Yang N, Greshock J, Megraw MS, Giannakakis A, Liang S, Naylor TL, Barchetti A, Ward MR, Yao G, Medina A, O'brien-Jenkins A, Katsaros D, Hatzigeorgiou A, Gimotty PA, Weber BL, Coukos G.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9136-41. Epub 2006 Jun 5.


Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.

Zhang L, Huang J, Yang N, Liang S, Barchetti A, Giannakakis A, Cadungog MG, O'Brien-Jenkins A, Massobrio M, Roby KF, Katsaros D, Gimotty P, Butzow R, Weber BL, Coukos G.

Cancer Res. 2006 May 1;66(9):4627-35.


Use of immuno-LCM to identify the in situ expression profile of cellular constituents of the tumor microenvironment.

Buckanovich RJ, Sasaroli D, O'brien-Jenkins A, Botbyl J, Conejo-Garcia JR, Benencia F, Liotta LA, Gimotty PA, Coukos G.

Cancer Biol Ther. 2006 Jun;5(6):635-42. Epub 2006 Jun 9.


Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth.

Zhang L, Yang N, Huang J, Buckanovich RJ, Liang S, Barchetti A, Vezzani C, O'Brien-Jenkins A, Wang J, Ward MR, Courreges MC, Fracchioli S, Medina A, Katsaros D, Weber BL, Coukos G.

Cancer Res. 2005 Feb 1;65(3):925-32.


RNA interference: a potential strategy for isoform-specific phosphatidylinositol 3-kinase targeted therapy in ovarian cancer.

Zhang L, Yang N, Liang S, Barchetti A, Vezzani C, Huang J, O'Brien-Jenkins A, Rubin SC, Coukos G.

Cancer Biol Ther. 2004 Dec;3(12):1283-9. Epub 2004 Dec 15.


Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer.

Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, O'Brien-Jenkins A, Randall TC, Rubin SC, Coukos G.

Cancer Res. 2003 Jun 15;63(12):3403-12.


Differential effects of prenatal cocaine exposure on selected subunit mRNAs of the GABA(A) receptor in rabbit anterior cingulate cortex.

Shumsky JS, Wu Y, Murphy EH, Nissanov J, O'Brien-Jenkins A, Grayson DR.

J Chem Neuroanat. 2002 Nov;24(4):243-55.


A mouse model of galactose-induced cataracts.

Ai Y, Zheng Z, O'Brien-Jenkins A, Bernard DJ, Wynshaw-Boris T, Ning C, Reynolds R, Segal S, Huang K, Stambolian D.

Hum Mol Genet. 2000 Jul 22;9(12):1821-7.


Cocaine administration in pregnant rabbits alters cortical structure and function in their progeny in the absence of maternal seizures.

Murphy EH, Fischer I, Friedman E, Grayson D, Jones L, Levitt P, O'Brien-Jenkins A, Wang HY, Wang XH.

Exp Brain Res. 1997 May;114(3):433-41.


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