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Epilepsy in adults. Thijs RD et al. Lancet. (2019)

Epilepsy. Devinsky O et al. Nat Rev Dis Primers. (2018)

De novo mutations in epileptic encephalopathies. Epi4K Consortium. et al. Nature. (2013)

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Items: 1 to 50 of 588


Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat.

Wright DK, Brady RD, Kamnaksh A, Trezise J, Sun M, McDonald SJ, Mychasiuk R, Kolbe SC, Law M, Johnston LA, O'Brien TJ, Agoston DV, Shultz SR.

Sci Rep. 2019 Oct 10;9(1):14626. doi: 10.1038/s41598-019-51267-w.


Innate Immunity in the Central Nervous System: A Missing Piece of the Autoimmune Encephalitis Puzzle?

Wesselingh R, Butzkueven H, Buzzard K, Tarlinton D, O'Brien TJ, Monif M.

Front Immunol. 2019 Sep 10;10:2066. doi: 10.3389/fimmu.2019.02066. eCollection 2019. Review.


Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy.

O'Brien TJ, Lorenzo MF, Zhao Y, Neal Ii RE, Robertson JL, Goldberg SN, Davalos RV.

Int J Hyperthermia. 2019;36(1):953-963. doi: 10.1080/02656736.2019.1657187.


Tau Related Pathways as a Connecting Link between Epilepsy and Alzheimer's Disease.

Paudel YN, Angelopoulou E, Jones NC, O'Brien TJ, Kwan P, Piperi C, Othman I, Shaikh MF.

ACS Chem Neurosci. 2019 Oct 16;10(10):4199-4212. doi: 10.1021/acschemneuro.9b00460. Epub 2019 Sep 30.


The genetic ablation of tau improves long-term, but not short-term, functional outcomes after experimental traumatic brain injury in mice.

Tan XL, Zheng P, Wright DK, Sun M, Brady RD, Liu S, McDonald SJ, Mychasiuk R, Cenap S, Jones NC, O'Brien TJ, Shultz SR.

Brain Inj. 2019 Sep 16:1-9. doi: 10.1080/02699052.2019.1667539. [Epub ahead of print]


An animal model of genetic predisposition to develop acquired epileptogenesis: The FAST and SLOW rats.

Leung WL, Casillas-Espinosa P, Sharma P, Perucca P, Powell K, O'Brien TJ, Semple BD.

Epilepsia. 2019 Oct;60(10):2023-2036. doi: 10.1111/epi.16329. Epub 2019 Aug 29. Review.


Comparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy.

Silvennoinen K, de Lange N, Zagaglia S, Balestrini S, Androsova G, Wassenaar M, Auce P, Avbersek A, Becker F, Berghuis B, Campbell E, Coppola A, Francis B, Wolking S, Cavalleri GL, Craig J, Delanty N, Johnson MR, Koeleman BPC, Kunz WS, Lerche H, Marson AG, O'Brien TJ, Sander JW, Sills GJ, Striano P, Zara F, van der Palen J, Krause R, Depondt C, Sisodiya SM; EpiPGX Consortium.

Epilepsia Open. 2019 Jul 4;4(3):420-430. doi: 10.1002/epi4.12349. eCollection 2019 Sep.


Disease-modifying effects of a novel T-type calcium channel antagonist, Z944, in a model of temporal lobe epilepsy.

Casillas-Espinosa PM, Shultz SR, Braine EL, Jones NC, Snutch TP, Powell KL, O'Brien TJ.

Prog Neurobiol. 2019 Aug 13:101677. doi: 10.1016/j.pneurobio.2019.101677. [Epub ahead of print]


Epilepsy and seizure-related deaths: Mortality statistics do not tell the complete story.

Panelli RJ, O'Brien TJ.

Epilepsy Behav. 2019 Sep;98(Pt A):266-272. doi: 10.1016/j.yebeh.2019.07.003. Epub 2019 Aug 10.


Acquired cardiac channelopathies in epilepsy: Evidence, mechanisms, and clinical significance.

Li MCH, O'Brien TJ, Todaro M, Powell KL.

Epilepsia. 2019 Sep;60(9):1753-1767. doi: 10.1111/epi.16301. Epub 2019 Jul 29. Review.


Pharmaceutical Benefits Scheme restrictions on anti-epileptic drug prescribing promote unsafe and outdated practice.

Gericke CA, O'Brien TJ.

Med J Aust. 2019 Jul;211(2):55-57.e1. doi: 10.5694/mja2.50246. Epub 2019 Jun 30. No abstract available.


Multiunit cluster firing patterns of piriform cortex and mediodorsal thalamus in absence epilepsy.

Young JC, Nasser HM, Casillas-Espinosa PM, O'Brien TJ, Jackson GD, Paolini AG.

Epilepsy Behav. 2019 Aug;97:229-243. doi: 10.1016/j.yebeh.2019.05.032. Epub 2019 Jun 26.


Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury: Chronic neuroinflammatory, behavioral, and epileptogenic consequences.

Webster KM, Shultz SR, Ozturk E, Dill LK, Sun M, Casillas-Espinosa P, Jones NC, Crack PJ, O'Brien TJ, Semple BD.

Exp Neurol. 2019 Oct;320:112979. doi: 10.1016/j.expneurol.2019.112979. Epub 2019 Jun 21.


Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences.

Scheltema MJ, O'Brien TJ, van den Bos W, de Bruin DM, Davalos RV, van den Geld CWM, Laguna MP, Neal RE 2nd, Varkarakis IM, Skolarikos A, Stricker PD, de Reijke TM, Arena CB, de la Rosette J.

Ther Adv Urol. 2019 Jun 7;11:1756287219852305. doi: 10.1177/1756287219852305. eCollection 2019 Jan-Dec.


Cav 3.2 T-type calcium channel mutation influences kindling-induced thalamic neuronal firing patterns in Genetic Absence Epilepsy Rats From Strasbourg.

Çarçak N, Ali I, Powell K, Zheng T, Onat F, O'Brien TJ.

Epilepsia. 2019 Jul;60(7):1378-1386. doi: 10.1111/epi.16076. Epub 2019 Jun 17.


The utility of an automated and ambulatory device for detecting and differentiating epileptic and psychogenic non-epileptic seizures.

Naganur VD, Kusmakar S, Chen Z, Palaniswami MS, Kwan P, O'Brien TJ.

Epilepsia Open. 2019 May 13;4(2):309-317. doi: 10.1002/epi4.12327. eCollection 2019 Jun.


Experimental High-Frequency Irreversible Electroporation Using a Single-Needle Delivery Approach for Nonthermal Pancreatic Ablation In Vivo.

O'Brien TJ, Passeri M, Lorenzo MF, Sulzer JK, Lyman WB, Swet JH, Vrochides D, Baker EH, Iannitti DA, Davalos RV, McKillop IH.

J Vasc Interv Radiol. 2019 Jun;30(6):854-862.e7. doi: 10.1016/j.jvir.2019.01.032.


Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis.

Casillas-Espinosa PM, Andrade P, Santana-Gomez C, Paananen T, Smith G, Ali I, Ciszek R, Ndode-Ekane XE, Brady RD, Tohka J, Hudson MR, Perucca P, Braine EL, Immonen R, Puhakka N, Shultz SR, Jones NC, Staba RJ, Pitkänen A, O'Brien TJ.

Epilepsy Res. 2019 Oct;156:106131. doi: 10.1016/j.eplepsyres.2019.04.011. Epub 2019 Apr 27.


Aged rats have an altered immune response and worse outcomes after traumatic brain injury.

Sun M, Brady RD, Casillas-Espinosa PM, Wright DK, Semple BD, Kim HA, Mychasiuk R, Sobey CG, O'Brien TJ, Vinh A, McDonald SJ, Shultz SR.

Brain Behav Immun. 2019 Aug;80:536-550. doi: 10.1016/j.bbi.2019.04.038. Epub 2019 Apr 27.


Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems.

Sharma R, Shultz SR, Robinson MJ, Belli A, Hibbs ML, O'Brien TJ, Semple BD.

Brain Behav Immun. 2019 Jul;79:63-74. doi: 10.1016/j.bbi.2019.04.034. Epub 2019 Apr 25. Review.


Focal stimulation of the sheep motor cortex with a chronically implanted minimally invasive electrode array mounted on an endovascular stent.

Opie NL, John SE, Rind GS, Ronayne SM, Wong YT, Gerboni G, Yoo PE, Lovell TJH, Scordas TCM, Wilson SL, Dornom A, Vale T, O'Brien TJ, Grayden DB, May CN, Oxley TJ.

Nat Biomed Eng. 2018 Dec;2(12):907-914. doi: 10.1038/s41551-018-0321-z. Epub 2018 Dec 3.


Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis.

Santana-Gomez C, Andrade P, Hudson MR, Paananen T, Ciszek R, Smith G, Ali I, Rundle BK, Ndode-Ekane XE, Casillas-Espinosa PM, Immonen R, Puhakka N, Jones N, Brady RD, Perucca P, Shultz SR, Pitkänen A, O'Brien TJ, Staba R.

Epilepsy Res. 2019 Oct;156:106110. doi: 10.1016/j.eplepsyres.2019.03.008. Epub 2019 Mar 15.


Targeting Glioma Stem Cells by Functional Inhibition of Dynamin 2: A Novel Treatment Strategy for Glioblastoma.

Luwor R, Morokoff AP, Amiridis S, D'Abaco G, Paradiso L, Stylli SS, Nguyen HPT, Tarleton M, Young KA, O'Brien TJ, Robinson PJ, Chircop M, McCluskey A, Jones NC.

Cancer Invest. 2019;37(3):144-155. doi: 10.1080/07357907.2019.1582060. Epub 2019 Mar 25.


Randomized trial of add-on triheptanoin vs medium chain triglycerides in adults with refractory epilepsy.

Borges K, Kaul N, Germaine J, Kwan P, O'Brien TJ.

Epilepsia Open. 2019 Feb 22;4(1):153-163. doi: 10.1002/epi4.12308. eCollection 2019 Mar.


A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine.

Berghuis B, Stapleton C, Sonsma ACM, Hulst J, de Haan GJ, Lindhout D, Demurtas R; EpiPGX Consortium, Krause R, Depondt C, Kunz WS, Zara F, Striano P, Craig J, Auce P, Marson AG, Stefansson H, O'Brien TJ, Johnson MR, Sills GJ, Wolking S, Lerche H, Sisodiya SM, Sander JW, Cavalleri GL, Koeleman BPC, McCormack M.

Epilepsia Open. 2019 Jan 17;4(1):102-109. doi: 10.1002/epi4.12297. eCollection 2019 Mar.


A universal automated tool for reliable detection of seizures in rodent models of acquired and genetic epilepsy.

Casillas-Espinosa PM, Sargsyan A, Melkonian D, O'Brien TJ.

Epilepsia. 2019 Apr;60(4):783-791. doi: 10.1111/epi.14691. Epub 2019 Mar 13.


Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging.

Neal A, Moffat BA, Stein JM, Nanga RPR, Desmond P, Shinohara RT, Hariharan H, Glarin R, Drummond K, Morokoff A, Kwan P, Reddy R, O'Brien TJ, Davis KA.

Neuroimage Clin. 2019;22:101694. doi: 10.1016/j.nicl.2019.101694. Epub 2019 Jan 29.


Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ndode-Ekane XE, Santana-Gomez C, Casillas-Espinosa PM, Ali I, Brady RD, Smith G, Andrade P, Immonen R, Puhakka N, Hudson MR, Braine EL, Shultz SR, Staba RJ, O'Brien TJ, Pitkänen A.

Epilepsy Res. 2019 Mar;151:7-16. doi: 10.1016/j.eplepsyres.2019.01.006. Epub 2019 Jan 18.


Epilepsy in adults.

Thijs RD, Surges R, O'Brien TJ, Sander JW.

Lancet. 2019 Feb 16;393(10172):689-701. doi: 10.1016/S0140-6736(18)32596-0. Epub 2019 Jan 24. Review.


Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis.

Immonen R, Smith G, Brady RD, Wright D, Johnston L, Harris NG, Manninen E, Salo R, Branch C, Duncan D, Cabeen R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Shultz SR, Andrade P, Puhakka N, Staba RJ, O'Brien TJ, Toga AW, Pitkänen A, Gröhn O.

Epilepsy Res. 2019 Feb;150:46-57. doi: 10.1016/j.eplepsyres.2019.01.001. Epub 2019 Jan 7.


A recurrent nova super-remnant in the Andromeda galaxy.

Darnley MJ, Hounsell R, O'Brien TJ, Henze M, Rodríguez-Gil P, Shafter AW, Shara MM, Vaytet NMH, Bode MF, Ciardullo R, Davis BD, Galera-Rosillo R, Harman DJ, Harvey EJ, Healy MW, Ness JU, Ribeiro VARM, Williams SC.

Nature. 2019 Jan;565(7740):460-463. doi: 10.1038/s41586-018-0825-4. Epub 2019 Jan 9.


A Concomitant Muscle Injury Does Not Worsen Traumatic Brain Injury Outcomes in Mice.

Sun M, Brady RD, van der Poel C, Apted D, Semple BD, Church JE, O'Brien TJ, McDonald SJ, Shultz SR.

Front Neurol. 2018 Dec 11;9:1089. doi: 10.3389/fneur.2018.01089. eCollection 2018.


Metabolic patterns and seizure outcomes following anterior temporal lobectomy.

Cahill V, Sinclair B, Malpas CB, McIntosh AM, Chen Z, Vivash LE, O'Shea MF, Wilson SJ, Desmond PM, Berlangieri SU, Hicks RJ, Rowe CC, Morokoff AP, King JA, Fabinyi GC, Kaye AH, Kwan P, Berkovic SF, O'Brien TJ.

Ann Neurol. 2019 Feb;85(2):241-250. doi: 10.1002/ana.25405. Epub 2019 Jan 17.


Informatics tools to assess the success of procedural harmonization in preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ciszek R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Smith G, Puhakka N, Lapinlampi N, Andrade P, Kamnaksh A, Immonen R, Paananen T, Hudson MR, Brady RD, Shultz SR, O'Brien TJ, Staba RJ, Tohka J, Pitkänen A.

Epilepsy Res. 2019 Feb;150:17-26. doi: 10.1016/j.eplepsyres.2018.12.010. Epub 2018 Dec 27.


Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register.

Vajda FJE, Graham JE, Hitchcock AA, Lander CM, O'Brien TJ, Eadie MJ.

Seizure. 2019 Feb;65:6-11. doi: 10.1016/j.seizure.2018.12.006. Epub 2018 Dec 19.


The ACCOuNT Consortium: A Model for the Discovery, Translation, and Implementation of Precision Medicine in African Americans.

Friedman PN, Shaazuddin M, Gong L, Grossman RL, Harralson AF, Klein TE, Lee NH, Miller DC, Nutescu EA, O'Brien TJ, O'Donnell PH, O'Leary KJ, Tuck M, Meltzer DO, Perera MA.

Clin Transl Sci. 2019 May;12(3):209-217. doi: 10.1111/cts.12608. Epub 2019 Feb 12. Review.


Harmonization of pipeline for preclinical multicenter plasma protein and miRNA biomarker discovery in a rat model of post-traumatic epileptogenesis.

Kamnaksh A, Puhakka N, Ali I, Smith G, Aniceto R, McCullough J, Das Gupta S, Ndode-Ekane XE, Brady R, Casillas-Espinosa P, Hudson M, Santana-Gomez C, Immonen R, Abreu PA, Jones N, Shultz S, Staba RJ, O'Brien TJ, Agoston D, Pitkänen A.

Epilepsy Res. 2019 Jan;149:92-101. doi: 10.1016/j.eplepsyres.2018.11.009. Epub 2018 Nov 26.


Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring.

Sivathamboo S, Farrand S, Chen Z, White EJ, Pattichis AA, Hollis C, Carino J, Roberts CJ, Minogue T, Jones NC, Yerra R, French C, Perucca P, Kwan P, Velakoulis D, O'Brien TJ, Goldin J.

Neurology. 2019 Jan 15;92(3):e194-e204. doi: 10.1212/WNL.0000000000006776. Epub 2018 Dec 14.


Novel features for capturing temporal variations of rhythmic limb movement to distinguish convulsive epileptic and psychogenic nonepileptic seizures.

Kusmakar S, Karmakar C, Yan B, Muthuganapathy R, Kwan P, O'Brien TJ, Palaniswami MS.

Epilepsia. 2019 Jan;60(1):165-174. doi: 10.1111/epi.14619. Epub 2018 Dec 9.


High-Frequency Neuronal Oscillatory Abnormalities in the Phospholipase C-β1 Knockout Mouse Model of Schizophrenia.

Hudson MR, Hannan AJ, O'Brien TJ, Jones NC.

Int J Neuropsychopharmacol. 2019 Mar 1;22(3):221-231. doi: 10.1093/ijnp/pyy097.


Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice.

Webster KM, Sun M, Crack PJ, O'Brien TJ, Shultz SR, Semple BD.

J Comp Neurol. 2019 Apr 15;527(6):1102-1117. doi: 10.1002/cne.24589. Epub 2018 Dec 30.


Author Correction: Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable.

John SE, Opie NL, Wong YT, Rind GS, Ronayne SM, Gerboni G, Bauquier SH, O'Brien TJ, May CN, Grayden DB, Oxley TJ.

Sci Rep. 2018 Nov 27;8(1):17469. doi: 10.1038/s41598-018-36257-8.


Determining the cost of first-ever seizures: A narrative review and future directions.

Foster E, Ademi Z, Lawn N, Chen Z, Carney P, Liew D, O'Brien TJ, Kwan P.

Epilepsy Behav. 2019 Jan;90:291-294. doi: 10.1016/j.yebeh.2018.10.045. Epub 2018 Nov 23. No abstract available.


Onset Detection of Epileptic Seizures From Accelerometry Signal.

Kusmakar S, Karmakar CK, Yan B, O'Brien TJ, Muthuganapathy R, Palaniswami M.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1-4. doi: 10.1109/EMBC.2018.8513669.


Cesarean section in Australian women with epilepsy.

Vajda FJE, O'Brien TJ, Graham JE, Hitchcock AA, Kuhn RJP, Lander CM, Eadie MJ.

Epilepsy Behav. 2018 Dec;89:126-129. doi: 10.1016/j.yebeh.2018.10.008. Epub 2018 Nov 7.


Feasibility of identifying the ideal locations for motor intention decoding using unimodal and multimodal classification at 7T-fMRI.

Yoo PE, Oxley TJ, John SE, Opie NL, Ordidge RJ, O'Brien TJ, Hagan MA, Wong YT, Moffat BA.

Sci Rep. 2018 Oct 22;8(1):15556. doi: 10.1038/s41598-018-33839-4.


Generalized polyspike train: An EEG biomarker of drug-resistant idiopathic generalized epilepsy.

Sun Y, Seneviratne U, Perucca P, Chen Z, Tan MK, O'Brien TJ, D'Souza W, Kwan P.

Neurology. 2018 Nov 6;91(19):e1822-e1830. doi: 10.1212/WNL.0000000000006472. Epub 2018 Oct 12. Erratum in: Neurology. 2018 Dec 11;91(24):1117.


Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.

Cardoso BR, Roberts BR, Malpas CB, Vivash L, Genc S, Saling MM, Desmond P, Steward C, Hicks RJ, Callahan J, Brodtmann A, Collins S, Macfarlane S, Corcoran NM, Hovens CM, Velakoulis D, O'Brien TJ, Hare DJ, Bush AI.

Neurotherapeutics. 2019 Jan;16(1):192-202. doi: 10.1007/s13311-018-0662-z.


The use of antidepressant drugs in pregnant women with epilepsy: A study from the Australian Pregnancy Register.

Sivathamboo N, Hitchcock A, Graham J, Sivathamboo S, Chen Z, O'Brien TJ, Vajda FJE.

Epilepsia. 2018 Sep;59(9):1696-1704. doi: 10.1111/epi.14539. Epub 2018 Aug 24.

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