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Items: 33

1.

Microbiota dysbiosis: a new piece in the understanding of the carcinogenesis puzzle.

García-Castillo V, Sanhueza E, McNerney E, Onate SA, García A.

J Med Microbiol. 2016 Dec;65(12):1347-1362. doi: 10.1099/jmm.0.000371. Epub 2016 Oct 21. Review.

PMID:
27902422
2.

Bone stroma-derived cells change coregulators recruitment to androgen receptor and decrease cell proliferation in androgen-sensitive and castration-resistant prostate cancer cells.

Villagran MA, Gutierrez-Castro FA, Pantoja DF, Alarcon JC, Fariña MA, Amigo RF, Muñoz-Godoy NA, Pinilla MG, Peña EA, Gonzalez-Chavarria I, Toledo JR, Rivas CI, Vera JC, McNerney EM, Onate SA.

Biochem Biophys Res Commun. 2015 Nov 27;467(4):1039-45. doi: 10.1016/j.bbrc.2015.10.009. Epub 2015 Oct 20.

PMID:
26494300
3.

Cis-regulatory elements involved in species-specific transcriptional regulation of the SVCT1 gene in rat and human hepatoma cells.

Muñoz A, Villagrán M, Guzmán P, Solíz C, Gatica M, Aylwin C, Sweet K, Maldonado M, Escobar E, Reyes AM, Toledo JR, Sánchez O, Oñate SA, Carlos Vera J, Rivas CI.

Free Radic Biol Med. 2015 Aug;85:183-96. doi: 10.1016/j.freeradbiomed.2015.04.024. Epub 2015 Apr 28.

PMID:
25933589
4.

Lectin-like oxidized LDL receptor-1 is an enhancer of tumor angiogenesis in human prostate cancer cells.

González-Chavarría I, Cerro RP, Parra NP, Sandoval FA, Zuñiga FA, Omazábal VA, Lamperti LI, Jiménez SP, Fernandez EA, Gutiérrez NA, Rodriguez FS, Onate SA, Sánchez O, Vera JC, Toledo JR.

PLoS One. 2014 Aug 29;9(8):e106219. doi: 10.1371/journal.pone.0106219. eCollection 2014.

5.

Altered corepressor SMRT expression and recruitment to target genes as a mechanism that change the response to androgens in prostate cancer progression.

Godoy AS, Sotomayor PC, Villagran M, Yacoub R, Montecinos VP, McNerney EM, Moser M, Foster BA, Onate SA.

Biochem Biophys Res Commun. 2012 Jul 6;423(3):564-70. doi: 10.1016/j.bbrc.2012.06.005. Epub 2012 Jun 10.

PMID:
22695118
6.

Biochemical characterization of nuclear receptors for vitamin D3 and glucocorticoids in prostate stroma cell microenvironment.

Hidalgo AA, Montecinos VP, Paredes R, Godoy AS, McNerney EM, Tovar H, Pantoja D, Johnson C, Trump D, Onate SA.

Biochem Biophys Res Commun. 2011 Aug 19;412(1):13-9. doi: 10.1016/j.bbrc.2011.06.181. Epub 2011 Jul 5.

PMID:
21763285
7.

Androgen receptor is causally involved in the homeostasis of the human prostate endothelial cell.

Godoy A, Watts A, Sotomayor P, Montecinos VP, Huss WJ, Onate SA, Smith GJ.

Endocrinology. 2008 Jun;149(6):2959-69. doi: 10.1210/en.2007-1078. Epub 2008 Feb 21.

8.

Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione.

Montecinos V, Guzmán P, Barra V, Villagrán M, Muñoz-Montesino C, Sotomayor K, Escobar E, Godoy A, Mardones L, Sotomayor P, Guzmán C, Vásquez O, Gallardo V, van Zundert B, Bono MR, Oñate SA, Bustamante M, Cárcamo JG, Rivas CI, Vera JC.

J Biol Chem. 2007 May 25;282(21):15506-15. Epub 2007 Apr 2.

9.

Altered VDR-mediated transcriptional activity in prostate cancer stroma.

Hidalgo AA, Paredes R, Garcia VM, Flynn G, Johnson CS, Trump DL, Onate SA.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):731-6.

PMID:
17368189
10.
11.

Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2. Activation by sodium and absolute dependence on bivalent cations.

Godoy A, Ormazabal V, Moraga-Cid G, Zúñiga FA, Sotomayor P, Barra V, Vasquez O, Montecinos V, Mardones L, Guzmán C, Villagrán M, Aguayo LG, Oñate SA, Reyes AM, Cárcamo JG, Rivas CI, Vera JC.

J Biol Chem. 2007 Jan 5;282(1):615-24. Epub 2006 Sep 29.

12.

Hypoxia increases androgen receptor activity in prostate cancer cells.

Park SY, Kim YJ, Gao AC, Mohler JL, Onate SA, Hidalgo AA, Ip C, Park EM, Yoon SY, Park YM.

Cancer Res. 2006 May 15;66(10):5121-9.

13.

Mechanisms of selenium down-regulation of androgen receptor signaling in prostate cancer.

Chun JY, Nadiminty N, Lee SO, Onate SA, Lou W, Gao AC.

Mol Cancer Ther. 2006 Apr;5(4):913-8.

14.

Selenium disrupts estrogen signaling by altering estrogen receptor expression and ligand binding in human breast cancer cells.

Lee SO, Nadiminty N, Wu XX, Lou W, Dong Y, Ip C, Onate SA, Gao AC.

Cancer Res. 2005 Apr 15;65(8):3487-92.

15.

Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway.

Lee SO, Lou W, Hou M, Onate SA, Gao AC.

Oncogene. 2003 Sep 11;22(39):7981-8.

PMID:
12970746
16.

Stat3 enhances transactivation of steroid hormone receptors.

De Miguel F, Lee SO, Onate SA, Gao AC.

Nucl Recept. 2003 Jun 13;1(1):3.

17.

Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing.

García M, Millán C, Balmaceda-Aguilera C, Castro T, Pastor P, Montecinos H, Reinicke K, Zúñiga F, Vera JC, Oñate SA, Nualart F.

J Neurochem. 2003 Aug;86(3):709-24.

18.

Steroid receptor and ligand-dependent interaction with coactivator proteins.

Oñate SA.

Methods Mol Biol. 2001;177:199-209. No abstract available.

PMID:
11530607
19.

A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex.

Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW.

Cell. 1999 Apr 2;97(1):17-27.

21.
22.

Steroid receptor coactivator-1 is a histone acetyltransferase.

Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW.

Nature. 1997 Sep 11;389(6647):194-8.

PMID:
9296499
23.

Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.

Shibata H, Spencer TE, Oñate SA, Jenster G, Tsai SY, Tsai MJ, O'Malley BW.

Recent Prog Horm Res. 1997;52:141-64; discussion 164-5. Review.

PMID:
9238851
24.

CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.

Smith CL, Oñate SA, Tsai MJ, O'Malley BW.

Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):8884-8.

25.

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily.

Oñate SA, Tsai SY, Tsai MJ, O'Malley BW.

Science. 1995 Nov 24;270(5240):1354-7.

PMID:
7481822
26.

The DNA-bending protein HMG-1 enhances progesterone receptor binding to its target DNA sequences.

Oñate SA, Prendergast P, Wagner JP, Nissen M, Reeves R, Pettijohn DE, Edwards DP.

Mol Cell Biol. 1994 May;14(5):3376-91.

27.

Nuclear accessory factors enhance the binding of progesterone receptor to specific target DNA.

Prendergast P, Oñate SA, Christensen K, Edwards DP.

J Steroid Biochem Mol Biol. 1994 Jan;48(1):1-13. Review.

PMID:
8136295
28.

Effects of the steroid antagonist RU486 on dimerization of the human progesterone receptor.

DeMarzo AM, Oñate SA, Nordeen SK, Edwards DP.

Biochemistry. 1992 Nov 3;31(43):10491-501.

PMID:
1420166
29.

Evidence that heat shock protein-70 associated with progesterone receptors is not involved in receptor-DNA binding.

Oñate SA, Estes PA, Welch WJ, Nordeen SK, Edwards DP.

Mol Endocrinol. 1991 Dec;5(12):1993-2004.

PMID:
1791844
30.

Characterization and functional properties of the A and B forms of human progesterone receptors synthesized in a baculovirus system.

Christensen K, Estes PA, Oñate SA, Beck CA, DeMarzo A, Altmann M, Lieberman BA, St John J, Nordeen SK, Edwards DP.

Mol Endocrinol. 1991 Nov;5(11):1755-70.

PMID:
1779977
31.

Mechanisms controlling steroid receptor binding to specific DNA sequences.

Edwards DP, DeMarzo AM, Oñate SA, Beck CA, Estes PA, Nordeen SK.

Steroids. 1991 May;56(5):271-8.

PMID:
1652169
32.
33.

Human progesterone receptor complexed with the antagonist RU 486 binds to hormone response elements in a structurally altered form.

el-Ashry D, Oñate SA, Nordeen SK, Edwards DP.

Mol Endocrinol. 1989 Oct;3(10):1545-58.

PMID:
2608048

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