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Items: 9

1.

Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties.

Nyström EEL, Arike L, Ehrencrona E, Hansson GC, Johansson MEV.

J Biol Chem. 2019 Nov 8;294(45):17075-17089. doi: 10.1074/jbc.RA119.009940. Epub 2019 Sep 29.

2.

Corrigendum: Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium.

Vega G, Guequén A, Johansson MEV, Arike L, Martínez-Abad B, Nyström EEL, Scudieri P, Pedemonte N, Millar-Büchner P, Philp AR, Galietta LJ, Hansson GC, Flores CA.

Front Physiol. 2019 Aug 27;10:1040. doi: 10.3389/fphys.2019.01040. eCollection 2019.

3.

The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.

Volk JK, Nyström EEL, van der Post S, Abad BM, Schroeder BO, Johansson Å, Svensson F, Jäverfelt S, Johansson MEV, Hansson GC, Birchenough GMH.

J Exp Med. 2019 Nov 4;216(11):2602-2618. doi: 10.1084/jem.20190679. Epub 2019 Aug 16.

PMID:
31420376
4.

Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium.

Vega G, Guequén A, Johansson MEV, Arike L, Martínez-Abad B, Nyström EEL, Scudieri P, Pedemonte N, Millar-Büchner P, Philp AR, Galietta LJ, Hansson GC, Flores CA.

Front Physiol. 2019 Jun 13;10:694. doi: 10.3389/fphys.2019.00694. eCollection 2019. Erratum in: Front Physiol. 2019 Aug 27;10:1040.

5.

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity.

Nyström EEL, Birchenough GMH, van der Post S, Arike L, Gruber AD, Hansson GC, Johansson MEV.

EBioMedicine. 2018 Jul;33:134-143. doi: 10.1016/j.ebiom.2018.05.031. Epub 2018 Jun 7.

6.

Functional mucous layer and healing of proximal colonic anastomoses in an experimental model.

Bosmans JW, Jongen AC, Birchenough GM, Nyström EE, Gijbels MJ, Derikx JP, Bouvy ND, Hansson GC.

Br J Surg. 2017 Apr;104(5):619-630. doi: 10.1002/bjs.10456. Epub 2017 Feb 13.

PMID:
28195642
7.

A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.

Birchenough GM, Nyström EE, Johansson ME, Hansson GC.

Science. 2016 Jun 24;352(6293):1535-42. doi: 10.1126/science.aaf7419.

8.

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.

Erickson NA, Nyström EE, Mundhenk L, Arike L, Glauben R, Heimesaat MM, Fischer A, Bereswill S, Birchenough GM, Gruber AD, Johansson ME.

PLoS One. 2015 Jul 10;10(7):e0131991. doi: 10.1371/journal.pone.0131991. eCollection 2015.

9.

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.

Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE, Wising C, Johansson ME, Hansson GC.

Immunol Rev. 2014 Jul;260(1):8-20. doi: 10.1111/imr.12182. Review.

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