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Items: 1 to 50 of 244

1.

Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells.

Nassa G, Salvati A, Tarallo R, Gigantino V, Alexandrova E, Memoli D, Sellitto A, Rizzo F, Malanga D, Mirante T, Morelli E, Nees M, Åkerfelt M, Kangaspeska S, Nyman TA, Milanesi L, Giurato G, Weisz A.

Sci Adv. 2019 Feb 6;5(2):eaav5590. doi: 10.1126/sciadv.aav5590. eCollection 2019 Feb.

2.

Mitochondrial stress response triggered by defects in protein synthesis quality control.

Richter U, Ng KY, Suomi F, Marttinen P, Turunen T, Jackson C, Suomalainen A, Vihinen H, Jokitalo E, Nyman TA, Isokallio MA, Stewart JB, Mancini C, Brusco A, Seneca S, Lombès A, Taylor RW, Battersby BJ.

Life Sci Alliance. 2019 Jan 25;2(1). pii: e201800219. doi: 10.26508/lsa.201800219. Print 2019 Feb.

3.

Characterization of the mitochondrial genome of Arge bella Wei & Du sp. nov. (Hymenoptera: Argidae).

Du S, Niu G, Nyman T, Wei M.

PeerJ. 2018 Dec 21;6:e6131. doi: 10.7717/peerj.6131. eCollection 2018.

4.

Endogenous toxins and the coupling of gregariousness to conspicuousness in Argidae and Pergidae sawflies.

Boevé JL, Nyman T, Shinohara A, Schmidt S.

Sci Rep. 2018 Dec 5;8(1):17636. doi: 10.1038/s41598-018-35925-z.

5.

A high-throughput pipeline for validation of antibodies.

Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, Nyman TA, Stensland ME, Zhou W, de Souza GA, Holden L, Stuchly J, Templin M, Lund-Johansen F.

Nat Methods. 2018 Nov;15(11):909-912. doi: 10.1038/s41592-018-0179-8. Epub 2018 Oct 30.

PMID:
30377371
6.

From Inflammasome to Exosome-Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?

Cypryk W, Nyman TA, Matikainen S.

Front Immunol. 2018 Sep 25;9:2188. doi: 10.3389/fimmu.2018.02188. eCollection 2018. Review.

7.

Finding flies in the mushroom soup: Host specificity of fungus-associated communities revisited with a novel molecular method.

Koskinen J, Roslin T, Nyman T, Abrego N, Michell C, Vesterinen EJ.

Mol Ecol. 2019 Jan;28(2):190-202. doi: 10.1111/mec.14810. Epub 2018 Aug 21.

PMID:
30040155
8.

The early effects of external and internal strategies on working memory updating training.

Laine M, Fellman D, Waris O, Nyman TJ.

Sci Rep. 2018 Mar 6;8(1):4045. doi: 10.1038/s41598-018-22396-5.

9.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells.

Giurato G, Nassa G, Salvati A, Alexandrova E, Rizzo F, Nyman TA, Weisz A, Tarallo R.

Sci Data. 2018 Mar 6;5:180031. doi: 10.1038/sdata.2018.31.

10.

Secretome profiling of Propionibacterium freudenreichii reveals highly variable responses even among the closely related strains.

Frohnmeyer E, Deptula P, Nyman TA, Laine PKS, Vihinen H, Paulin L, Auvinen P, Jokitalo E, Piironen V, Varmanen P, Savijoki K.

Microb Biotechnol. 2018 May;11(3):510-526. doi: 10.1111/1751-7915.13254. Epub 2018 Feb 28.

11.

Development and validation of PediaTrac™: A web-based tool to track developing infants.

Lajiness-O'Neill R, Brooks J, Lukomski A, Schilling S, Huth-Bocks A, Warschausky S, Flores AM, Swick C, Nyman T, Andersen T, Morris N, Schmitt TA, Bell-Smith J, Moir B, Hodges EK, Lyddy JE.

Infant Behav Dev. 2018 Feb;50:224-237. doi: 10.1016/j.infbeh.2018.01.008. Epub 2018 Feb 7.

PMID:
29427921
12.

Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications.

Nassa G, Giurato G, Cimmino G, Rizzo F, Ravo M, Salvati A, Nyman TA, Zhu Y, Vesterlund M, Lehtiö J, Golino P, Weisz A, Tarallo R.

Sci Rep. 2018 Jan 11;8(1):498. doi: 10.1038/s41598-017-18985-5.

13.

Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol.

Ekblad T, Verheugd P, Lindgren AE, Nyman T, Elofsson M, Schüler H.

SLAS Discov. 2018 Apr;23(4):353-362. doi: 10.1177/2472555217750870. Epub 2018 Jan 9.

PMID:
29316839
14.

Embracing Colonizations: A New Paradigm for Species Association Dynamics.

Nylin S, Agosta S, Bensch S, Boeger WA, Braga MP, Brooks DR, Forister ML, Hambäck PA, Hoberg EP, Nyman T, Schäpers A, Stigall AL, Wheat CW, Österling M, Janz N.

Trends Ecol Evol. 2018 Jan;33(1):4-14. doi: 10.1016/j.tree.2017.10.005. Epub 2017 Nov 4.

PMID:
29113696
15.

The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading.

Tarallo R, Giurato G, Bruno G, Ravo M, Rizzo F, Salvati A, Ricciardi L, Marchese G, Cordella A, Rocco T, Gigantino V, Pierri B, Cimmino G, Milanesi L, Ambrosino C, Nyman TA, Nassa G, Weisz A.

Genome Biol. 2017 Oct 6;18(1):189. doi: 10.1186/s13059-017-1321-0.

16.

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.

Bulanova D, Ianevski A, Bugai A, Akimov Y, Kuivanen S, Paavilainen H, Kakkola L, Nandania J, Turunen L, Ohman T, Ala-Hongisto H, Pesonen HM, Kuisma MS, Honkimaa A, Walton EL, Oksenych V, Lorey MB, Guschin D, Shim J, Kim J, Than TT, Chang SY, Hukkanen V, Kulesskiy E, Marjomaki VS, Julkunen I, Nyman TA, Matikainen S, Saarela JS, Sane F, Hober D, Gabriel G, De Brabander JK, Martikainen M, Windisch MP, Min JY, Bruzzone R, Aittokallio T, Vähä-Koskela M, Vapalahti O, Pulk A, Velagapudi V, Kainov DE.

Viruses. 2017 Sep 25;9(10). pii: E271. doi: 10.3390/v9100271.

17.

Proprotein convertase Furin1 expression in the Drosophila fat body is essential for a normal antimicrobial peptide response and bacterial host defense.

Aittomäki S, Valanne S, Lehtinen T, Matikainen S, Nyman TA, Rämet M, Pesu M.

FASEB J. 2017 Nov;31(11):4770-4782. doi: 10.1096/fj.201700296R. Epub 2017 Jul 13.

PMID:
28705811
18.

Proteomics to study macrophage response to viral infection.

Nyman TA, Matikainen S.

J Proteomics. 2018 May 30;180:99-107. doi: 10.1016/j.jprot.2017.06.018. Epub 2017 Jun 21. Review.

PMID:
28647517
19.

As time passes by: Observed motion-speed and psychological time during video playback.

Nyman TJ, Karlsson EPA, Antfolk J.

PLoS One. 2017 Jun 14;12(6):e0177855. doi: 10.1371/journal.pone.0177855. eCollection 2017.

20.

PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease.

Dumont V, Tolvanen TA, Kuusela S, Wang H, Nyman TA, Lindfors S, Tienari J, Nisen H, Suetsugu S, Plomann M, Kawachi H, Lehtonen S.

FASEB J. 2017 Sep;31(9):3978-3990. doi: 10.1096/fj.201601265R. Epub 2017 May 26.

21.

Inter- and intra- observer reliability of risk assessment of repetitive work without an explicit method.

Eliasson K, Palm P, Nyman T, Forsman M.

Appl Ergon. 2017 Jul;62:1-8. doi: 10.1016/j.apergo.2017.02.004. Epub 2017 Feb 16.

22.

Mass spectrometry-based proteomic exploration of the human immune system: focus on the inflammasome, global protein secretion, and T cells.

Nyman TA, Lorey MB, Cypryk W, Matikainen S.

Expert Rev Proteomics. 2017 May;14(5):395-407. doi: 10.1080/14789450.2017.1319768. Epub 2017 Apr 24. Review.

PMID:
28406322
23.

SnoN Stabilizes the SMAD3/SMAD4 Protein Complex.

Walldén K, Nyman T, Hällberg BM.

Sci Rep. 2017 Apr 11;7:46370. doi: 10.1038/srep46370.

24.

Food-web structure of willow-galling sawflies and their natural enemies across Europe.

Kopelke JP, Nyman T, Cazelles K, Gravel D, Vissault S, Roslin T.

Ecology. 2017 Jun;98(6):1730. doi: 10.1002/ecy.1832. Epub 2017 May 15.

PMID:
28369917
25.

Food-Like Growth Conditions Support Production of Active Vitamin B12 by Propionibacterium freudenreichii 2067 without DMBI, the Lower Ligand Base, or Cobalt Supplementation.

Deptula P, Chamlagain B, Edelmann M, Sangsuwan P, Nyman TA, Savijoki K, Piironen V, Varmanen P.

Front Microbiol. 2017 Mar 8;8:368. doi: 10.3389/fmicb.2017.00368. eCollection 2017.

26.

Development of evidence-based practice in occupational health services in Sweden: a 3-year follow-up of attitudes, barriers and facilitators.

Brämberg EB, Nyman T, Kwak L, Alipour A, Bergström G, Elinder LS, Hermansson U, Jensen I.

Int Arch Occup Environ Health. 2017 May;90(4):335-348. doi: 10.1007/s00420-017-1200-8. Epub 2017 Feb 15.

27.

Global Characterization of Protein Secretion from Human Macrophages Following Non-canonical Caspase-4/5 Inflammasome Activation.

Lorey MB, Rossi K, Eklund KK, Nyman TA, Matikainen S.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S187-S199. doi: 10.1074/mcp.M116.064840. Epub 2017 Feb 14.

28.

Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion.

Wasik AA, Dumont V, Tienari J, Nyman TA, Fogarty CL, Forsblom C, Lehto M, Lehtonen E, Groop PH, Lehtonen S.

Exp Cell Res. 2017 Jan 15;350(2):336-348. doi: 10.1016/j.yexcr.2016.12.010. Epub 2016 Dec 20.

29.

Regulation of kynurenine biosynthesis during influenza virus infection.

Gaelings L, Söderholm S, Bugai A, Fu Y, Nandania J, Schepens B, Lorey MB, Tynell J, Vande Ginste L, Le Goffic R, Miller MS, Kuisma M, Marjomäki V, De Brabander J, Matikainen S, Nyman TA, Bamford DH, Saelens X, Julkunen I, Paavilainen H, Hukkanen V, Velagapudi V, Kainov DE.

FEBS J. 2017 Jan;284(2):222-236. doi: 10.1111/febs.13966. Epub 2016 Dec 14.

30.

Identification of sawflies and horntails (Hymenoptera, 'Symphyta') through DNA barcodes: successes and caveats.

Schmidt S, Taeger A, Morinière J, Liston A, Blank SM, Kramp K, Kraus M, Schmidt O, Heibo E, Prous M, Nyman T, Malm T, Stahlhut J.

Mol Ecol Resour. 2017 Jul;17(4):670-685. doi: 10.1111/1755-0998.12614. Epub 2016 Nov 19.

PMID:
27768250
31.

Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes.

Anastasina M, Le May N, Bugai A, Fu Y, Söderholm S, Gaelings L, Ohman T, Tynell J, Kyttänen S, Barboric M, Nyman TA, Matikainen S, Julkunen I, Butcher SJ, Egly JM, Kainov DE.

Biochim Biophys Acta. 2016 Nov;1859(11):1440-1448. doi: 10.1016/j.bbagrm.2016.09.005. Epub 2016 Sep 21.

PMID:
27664935
32.

Proteomic and Bioinformatic Characterization of Extracellular Vesicles Released from Human Macrophages upon Influenza A Virus Infection.

Cypryk W, Lorey M, Puustinen A, Nyman TA, Matikainen S.

J Proteome Res. 2017 Jan 6;16(1):217-227. doi: 10.1021/acs.jproteome.6b00596. Epub 2016 Nov 15.

PMID:
27723984
33.

Multi-Omics Studies towards Novel Modulators of Influenza A Virus-Host Interaction.

Söderholm S, Fu Y, Gaelings L, Belanov S, Yetukuri L, Berlinkov M, Cheltsov AV, Anders S, Aittokallio T, Nyman TA, Matikainen S, Kainov DE.

Viruses. 2016 Sep 29;8(10). pii: E269. Review.

34.

Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages.

Välimäki E, Cypryk W, Virkanen J, Nurmi K, Turunen PM, Eklund KK, Åkerman KE, Nyman TA, Matikainen S.

J Immunol. 2016 Oct 15;197(8):3315-3325. Epub 2016 Sep 16.

35.

Generation and analyses of human synthetic antibody libraries and their application for protein microarrays.

Säll A, Walle M, Wingren C, Müller S, Nyman T, Vala A, Ohlin M, Borrebaeck CAK, Persson H.

Protein Eng Des Sel. 2016 Oct;29(10):427-437. doi: 10.1093/protein/gzw042. Epub 2016 Sep 1.

PMID:
27590051
36.

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling.

Varghese FS, Thaa B, Amrun SN, Simarmata D, Rausalu K, Nyman TA, Merits A, McInerney GM, Ng LFP, Ahola T.

J Virol. 2016 Oct 14;90(21):9743-9757. doi: 10.1128/JVI.01382-16. Print 2016 Nov 1.

37.

The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone.

Bæk KT, Bowman L, Millership C, Dupont Søgaard M, Kaever V, Siljamäki P, Savijoki K, Varmanen P, Nyman TA, Gründling A, Frees D.

MBio. 2016 Aug 9;7(4). pii: e01228-16. doi: 10.1128/mBio.01228-16.

38.

Phosphoproteomics to Characterize Host Response During Influenza A Virus Infection of Human Macrophages.

Söderholm S, Kainov DE, Öhman T, Denisova OV, Schepens B, Kulesskiy E, Imanishi SY, Corthals G, Hintsanen P, Aittokallio T, Saelens X, Matikainen S, Nyman TA.

Mol Cell Proteomics. 2016 Oct;15(10):3203-3219. Epub 2016 Aug 2.

39.

JNJ872 inhibits influenza A virus replication without altering cellular antiviral responses.

Fu Y, Gaelings L, Söderholm S, Belanov S, Nandania J, Nyman TA, Matikainen S, Anders S, Velagapudi V, Kainov DE.

Antiviral Res. 2016 Sep;133:23-31. doi: 10.1016/j.antiviral.2016.07.008. Epub 2016 Jul 20.

PMID:
27451344
40.

Inter-hemispheric plasticity in patients with median nerve injury.

Fornander L, Nyman T, Hansson T, Brismar T, Engström M.

Neurosci Lett. 2016 Aug 15;628:59-66. doi: 10.1016/j.neulet.2016.06.018. Epub 2016 Jun 9.

PMID:
27291455
41.

HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression.

Christensen MH, Jensen SB, Miettinen JJ, Luecke S, Prabakaran T, Reinert LS, Mettenleiter T, Chen ZJ, Knipe DM, Sandri-Goldin RM, Enquist LW, Hartmann R, Mogensen TH, Rice SA, Nyman TA, Matikainen S, Paludan SR.

EMBO J. 2016 Jul 1;35(13):1385-99. doi: 10.15252/embj.201593458. Epub 2016 May 27.

42.

Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine.

Söderholm S, Anastasina M, Islam MM, Tynell J, Poranen MM, Bamford DH, Stenman J, Julkunen I, Šaulienė I, De Brabander JK, Matikainen S, Nyman TA, Saelens X, Kainov D.

Antiviral Res. 2016 Feb;126:69-80. doi: 10.1016/j.antiviral.2015.12.011. Epub 2015 Dec 29.

43.

Penicillin G increases the synthesis of a suicidal marker (CidC) and virulence (HlgBC) proteins in Staphylococcus aureus biofilm cells.

Savijoki K, Skogman M, Fallarero A, Nyman TA, Sukura A, Vuorela P, Varmanen P.

Int J Med Microbiol. 2016 Jan;306(1):69-74. doi: 10.1016/j.ijmm.2015.11.006. Epub 2015 Dec 3.

PMID:
26725755
44.

Determinants of parasitoid communities of willow-galling sawflies: habitat overrides physiology, host plant and space.

Nyman T, Leppänen SA, Várkonyi G, Shaw MR, Koivisto R, Barstad TE, Vikberg V, Roininen H.

Mol Ecol. 2015 Oct;24(19):5059-74. doi: 10.1111/mec.13369. Epub 2015 Sep 26.

PMID:
26340615
45.

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.

Trésaugues L, Lundbäck T, Welin M, Flodin S, Nyman T, Silvander C, Gräslund S, Nordlund P.

PLoS One. 2015 Jun 29;10(6):e0131507. doi: 10.1371/journal.pone.0131507. eCollection 2015.

46.

Biological properties of extracellular vesicles and their physiological functions.

Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M, Kralj-Iglic V, Krämer-Albers EM, Laitinen S, Lässer C, Lener T, Ligeti E, Linē A, Lipps G, Llorente A, Lötvall J, Manček-Keber M, Marcilla A, Mittelbrunn M, Nazarenko I, Nolte-'t Hoen EN, Nyman TA, O'Driscoll L, Olivan M, Oliveira C, Pállinger É, Del Portillo HA, Reventós J, Rigau M, Rohde E, Sammar M, Sánchez-Madrid F, Santarém N, Schallmoser K, Ostenfeld MS, Stoorvogel W, Stukelj R, Van der Grein SG, Vasconcelos MH, Wauben MH, De Wever O.

J Extracell Vesicles. 2015 May 14;4:27066. doi: 10.3402/jev.v4.27066. eCollection 2015.

47.

The C terminus of NS1 protein of influenza A/WSN/1933(H1N1) virus modulates antiviral responses in infected human macrophages and mice.

Anastasina M, Schepens B, Söderholm S, Nyman TA, Matikainen S, Saksela K, Saelens X, Kainov DE.

J Gen Virol. 2015 Aug;96(8):2086-91. doi: 10.1099/vir.0.000171. Epub 2015 May 1.

PMID:
25934792
48.

Activating stimuli induce platelet microRNA modulation and proteome reorganisation.

Cimmino G, Tarallo R, Nassa G, De Filippo MR, Giurato G, Ravo M, Rizzo F, Conte S, Pellegrino G, Cirillo P, Calabro P, Öhman T, Nyman TA, Weisz A, Golino P.

Thromb Haemost. 2015 Jul;114(1):96-108. doi: 10.1160/TH14-09-0726. Epub 2015 Apr 23.

PMID:
25903651
49.

Phylogeny of Salix subgenus Salix s.l. (Salicaceae): delimitation, biogeography, and reticulate evolution.

Wu J, Nyman T, Wang DC, Argus GW, Yang YP, Chen JH.

BMC Evol Biol. 2015 Mar 4;15:31. doi: 10.1186/s12862-015-0311-7.

50.

Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.

Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ.

Genetics. 2015 May;200(1):221-35. doi: 10.1534/genetics.115.175596. Epub 2015 Mar 25.

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