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Items: 1 to 50 of 157

1.

Investigating associations between rural-to-urban migration and cardiometabolic disease in Malawi: a population-level study.

Chilunga FP, Musicha C, Tafatatha T, Geis S, Nyirenda MJ, Crampin AC, Price AJ.

Int J Epidemiol. 2019 Oct 11. pii: dyz198. doi: 10.1093/ije/dyz198. [Epub ahead of print]

PMID:
31603469
2.

Sex and area differences in the association between adiposity and lipid profile in Malawi.

Soares ALG, Banda L, Amberbir A, Jaffar S, Musicha C, Price A, Nyirenda MJ, Lawlor DA, Crampin A.

BMJ Glob Health. 2019 Sep 11;4(5):e001542. doi: 10.1136/bmjgh-2019-001542. eCollection 2019.

3.

Advancing research on emergency care systems in low-income and middle-income countries: ensuring high-quality care delivery systems.

Moresky RT, Razzak J, Reynolds T, Wallis LA, Wachira BW, Nyirenda M, Carlo WA, Lin J, Patel S, Bhoi S, Risko N, Wendle LA, Calvello Hynes EJ; National Institute of Health Fogarty International Center convened the Collaborative on Enhancing Emergency Care Research in LMICs (CLEER) .

BMJ Glob Health. 2019 Jul 29;4(Suppl 6):e001265. doi: 10.1136/bmjgh-2018-001265. eCollection 2019. Review.

4.

The Malawi NCD BRITE Consortium: Building Research Capacity, Implementation, and Translation Expertise for Noncommunicable Diseases.

van Oosterhout JJ, Hosseinipour M, Muula AS, Amberbir A, Wroe E, Berman J, Maliwichi-Nyirenda C, Mwapasa V, Crampin A, Makwero M, Singogo E, Gopal S, Baker U, Phiri S, Gordon SB, Tobe S, Chiwanda J, Masiye J, Parks J, Mitambo C, Gondwe A, Dullie L, Newsome B, Nyirenda M.

Glob Heart. 2019 Jun;14(2):149-154. doi: 10.1016/j.gheart.2019.05.004. Review.

PMID:
31324369
5.

Systematic Review of Hypertension and Diabetes Burden, Risk Factors, and Interventions for Prevention and Control in Malawi: The NCD BRITE Consortium.

Amberbir A, Lin SH, Berman J, Muula A, Jacoby D, Wroe E, Maliwichi-Nyirenda C, Mwapasa V, Crampin A, Makwero M, Singogo E, Phiri S, Gordon S, Tobe SW, Masiye J, Newsome B, Hosseinipour M, Nyirenda MJ, van Oosterhout JJ.

Glob Heart. 2019 Jun;14(2):109-118. doi: 10.1016/j.gheart.2019.05.001. Review.

PMID:
31324364
6.

The Kathmandu Declaration on Global CVD/Hypertension Research and Implementation Science: A Framework to Advance Implementation Research for Cardiovascular and Other Noncommunicable Diseases in Low- and Middle-Income Countries.

Aifah A, Iwelunmor J, Akwanalo C, Allison J, Amberbir A, Asante KP, Baumann A, Brown A, Butler M, Dalton M, Davila-Roman V, Fitzpatrick AL, Fort M, Goldberg R, Gondwe A, Ha D, He J, Hosseinipour M, Irazola V, Kamano J, Karengera S, Karmacharya BM, Koju R, Maharjan R, Mohan S, Mutabazi V, Mutimura E, Muula A, Narayan KMV, Nguyen H, Njuguna B, Nyirenda M, Ogedegbe G, van Oosterhout J, Onakomaiya D, Patel S, Paniagua-Ávila A, Ramirez-Zea M, Plange-Rhule J, Roche D, Shrestha A, Sharma H, Tandon N, Thu-Cuc N, Vaidya A, Vedanthan R, Weber MB.

Glob Heart. 2019 Jun;14(2):103-107. doi: 10.1016/j.gheart.2019.05.006. No abstract available.

PMID:
31324363
7.

ART Adherence Among Malawian Youth Enrolled in Teen Clubs: A Retrospective Chart Review.

McBride K, Parent J, Mmanga K, Chivwala M, Nyirenda MH, Schooley A, Mwambene JB, Dovel K, Lungu E, Balakasi K, Hoffman RM, Moucheraud C.

AIDS Behav. 2019 Sep;23(9):2629-2633. doi: 10.1007/s10461-019-02580-y.

PMID:
31292826
8.

Metabolomics in plasma of Malawian children 7 years after surviving severe acute malnutrition: "ChroSAM" a cohort study.

Bourdon C, Lelijveld N, Thompson D, Dalvi PS, Gonzales GB, Wang D, Alipour M, Wine E, Chimwezi E, Wells JC, Kerac M, Bandsma R, Nyirenda MJ.

EBioMedicine. 2019 Jul;45:464-472. doi: 10.1016/j.ebiom.2019.06.041. Epub 2019 Jun 27.

9.

Mobile Messaging Support Versus Usual Care for People With Type 2 Diabetes on Glycemic Control: Protocol for a Multicenter Randomized Controlled Trial.

Farmer A, Bobrow K, Leon N, Williams N, Phiri E, Namadingo H, Cooper S, Prince J, Crampin A, Besada D, Daviaud E, Yu LM, Ngoma J, Springer D, Pauly B, Norris S, Tarassenko L, Nyirenda M, Levitt N.

JMIR Res Protoc. 2019 May 30;8(6):e12377. doi: 10.2196/12377.

10.

Perceived Acceptability of a Facility-Based HIV Self-Test Intervention in Outpatient Waiting Spaces Among Adult Outpatients in Malawi: A Formative Study.

Shaba F, Offorjebe OA, Phiri K, Lungu E, Kalande P, Nyirenda M, Hoffman RM, Gupta S, Dovel K.

J Acquir Immune Defic Syndr. 2019 Jul 1;81(3):e92-e94. doi: 10.1097/QAI.0000000000002055. No abstract available.

PMID:
31194705
11.

Community-Level Knowledge and Perceptions of Stroke in Rural Malawi.

Mvula H, Chisambo C, Nyirenda V, Geis S, Glynn JR, Crampin AC, Nyirenda M, Smeeth L, Walker R, Price AJ.

Stroke. 2019 Jul;50(7):1846-1849. doi: 10.1161/STROKEAHA.119.025105. Epub 2019 Jun 5.

12.

Pregnancy, programming, and predisposition.

Nyirenda MJ, Byass P.

Lancet Glob Health. 2019 Apr;7(4):e404-e405. doi: 10.1016/S2214-109X(19)30051-8. Epub 2019 Feb 21. No abstract available.

13.

Understanding the manifestation of diabetes in sub Saharan Africa to inform therapeutic approaches and preventive strategies: a narrative review.

Kibirige D, Lumu W, Jones AG, Smeeth L, Hattersley AT, Nyirenda MJ.

Clin Diabetes Endocrinol. 2019 Feb 14;5:2. doi: 10.1186/s40842-019-0077-8. eCollection 2019. Review.

14.

Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis.

Mexhitaj I, Nyirenda MH, Li R, O'Mahony J, Rezk A, Rozenberg A, Moore CS, Johnson T, Sadovnick D, Collins DL, Arnold DL, Gran B, Yeh EA, Marrie RA, Banwell B, Bar-Or A.

Brain. 2019 Mar 1;142(3):617-632. doi: 10.1093/brain/awz017.

PMID:
30759186
15.

Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi.

Aston SJ, Ho A, Jary H, Huwa J, Mitchell T, Ibitoye S, Greenwood S, Joekes E, Daire A, Mallewa J, Everett D, Nyirenda M, Faragher B, Mwandumba HC, Heyderman RS, Gordon SB.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):359-369. doi: 10.1164/rccm.201807-1333OC.

16.

Establishment of trauma registry at Queen Elizabeth Central Hospital (QECH), Blantyre, Malawi and mapping of high risk geographic areas for trauma.

Chokotho LC, Mulwafu W, Nyirenda M, Mbomuwa FJ, Pandit HG, Le G, Lavy C.

World J Emerg Med. 2019;10(1):33-41. doi: 10.5847/wjem.j.1920-8642.2019.01.005.

17.

Brain MRI and cognitive function seven years after surviving an episode of severe acute malnutrition in a cohort of Malawian children.

Lelijveld N, Jalloh AA, Kampondeni SD, Seal A, Wells JC, Goyheneix M, Chimwezi E, Mallewa M, Nyirenda MJ, Heyderman RS, Kerac M.

Public Health Nutr. 2019 Jun;22(8):1406-1414. doi: 10.1017/S1368980018003282. Epub 2018 Dec 3.

18.

Essential medicines for emergency care in Africa.

Broccoli MC, Pigoga JL, Nyirenda M, Wallis LA, Calvello Hynes EJ.

Afr J Emerg Med. 2018 Sep;8(3):110-117. doi: 10.1016/j.afjem.2018.05.002. Epub 2018 Jun 29.

19.

Towards the third 90: improving viral load testing with a simple quality improvement program in health facilities in Malawi.

Hubbard J, Kakwesa G, Nyirenda M, Mwambene J, Bardon A, Balakasi K, Dovel K, Kalua T, Hoffman RM.

Int Health. 2019 May 1;11(3):215-220. doi: 10.1093/inthealth/ihy083.

PMID:
30383224
20.

Integrated care for human immunodeficiency virus, diabetes and hypertension in Africa.

Garrib A, Birungi J, Lesikari S, Namakoola I, Njim T, Cuevas L, Niessen L, Mugisha K, Mutungi G, Mghamba J, Ramaiya K, Jaffar S, Mfinanga S, Nyirenda M.

Trans R Soc Trop Med Hyg. 2018 Sep 28. doi: 10.1093/trstmh/try098. [Epub ahead of print]

PMID:
30265362
21.

Evaluating the integration of HIV self-testing into low-resource health systems: study protocol for a cluster-randomized control trial from EQUIP Innovations.

Dovel K, Shaba F, Nyirenda M, Offorjebe OA, Balakasi K, Phiri K, Nichols B, Tseng CH, Bardon A, Ngona K, Hoffman R.

Trials. 2018 Sep 17;19(1):498. doi: 10.1186/s13063-018-2878-y.

22.

Epidemiology of Severe Acute Respiratory Illness and Risk Factors for Influenza Infection and Clinical Severity among Adults in Malawi, 2011-2013.

Ho A, Mallewa J, Peterson I, SanJoaquin M, Garg S, Bar-Zeev N, Menyere M, Alaerts M, Mapurisa G, Chilombe M, Nyirenda M, Lalloo DG, Rothe C, Widdowson MA, McMorrow M, French N, Everett D, Heyderman RS.

Am J Trop Med Hyg. 2018 Sep;99(3):772-779. doi: 10.4269/ajtmh.17-0905. Epub 2018 Jul 19.

23.

Simple Screening Tool to Help Identify High-Risk Children for Targeted HIV Testing in Malawian Inpatient Wards.

Moucheraud C, Chasweka D, Nyirenda M, Schooley A, Dovel K, Hoffman RM.

J Acquir Immune Defic Syndr. 2018 Nov 1;79(3):352-357. doi: 10.1097/QAI.0000000000001804.

PMID:
29995704
24.

Dietary sodium intake in urban and rural Malawi, and directions for future interventions.

Prynn JE, Banda L, Amberbir A, Price AJ, Kayuni N, Jaffar S, Crampin AC, Smeeth L, Nyirenda M.

Am J Clin Nutr. 2018 Sep 1;108(3):587-593. doi: 10.1093/ajcn/nqy125.

25.

HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.

Ekoru K, Young EH, Dillon DG, Gurdasani D, Stehouwer N, Faurholt-Jepsen D, Levitt NS, Crowther NJ, Nyirenda M, Njelekela MA, Ramaiya K, Nyan O, Adewole OO, Anastos K, Compostella C, Dave JA, Fourie CM, Friis H, Kruger IM, Longenecker CT, Maher DP, Mutimura E, Ndhlovu CE, Praygod G, Pefura Yone EW, Pujades-Rodriguez M, Range N, Sani MU, Sanusi M, Schutte AE, Sliwa K, Tien PC, Vorster EH, Walsh C, Gareta D, Mashili F, Sobngwi E, Adebamowo C, Kamali A, Seeley J, Smeeth L, Pillay D, Motala AA, Kaleebu P, Sandhu MS.

Glob Health Epidemiol Genom. 2018;3. pii: e7. doi: 10.1017/gheg.2018.7. Epub 2018 May 8.

26.

AcSDKP is down-regulated in anaemia induced by Trypanosoma brucei infection in mice.

Musaya J, Matovu E, Senga E, Nyirenda M, Chisi J.

Malawi Med J. 2017 Sep;29(3):259-264. doi: 10.4314/mmj.v29i3.6.

27.

Glycated haemoglobin A1c (HbA1c) for detection of diabetes mellitus and impaired fasting glucose in Malawi: a diagnostic accuracy study.

Rathod SD, Crampin AC, Musicha C, Kayuni N, Banda L, Saul J, McLean E, Branson K, Jaffar S, Nyirenda MJ.

BMJ Open. 2018 May 5;8(5):e020972. doi: 10.1136/bmjopen-2017-020972.

28.

How does the association of general and central adiposity with glycaemia and blood pressure differ by gender and area of residence in a Malawian population: a cross-sectional study.

Mudie K, Lawlor DA, Pearce N, Crampin A, Tomlinson L, Tafatatha T, Musicha C, Nitsch D, Smeeth L, Nyirenda MJ.

Int J Epidemiol. 2018 Apr 10. doi: 10.1093/ije/dyy047. [Epub ahead of print]

29.

Essential medicines for emergency care in Africa.

Broccoli MC, Pigoga JL, Nyirenda M, Wallis L, Calvello Hynes EJ.

Emerg Med J. 2018 Jul;35(7):412-419. doi: 10.1136/emermed-2017-207396. Epub 2018 Apr 7.

PMID:
29627770
30.

Developmental Origins of Health and Disease: the relevance to developing nations.

Mandy M, Nyirenda M.

Int Health. 2018 Mar 1;10(2):66-70. doi: 10.1093/inthealth/ihy006.

31.

Developmental origins of health and disease in Africa-influencing early life.

Davies JI, Macnab AJ, Byass P, Norris SA, Nyirenda M, Singhal A, Sobngwi E, Daar AS.

Lancet Glob Health. 2018 Mar;6(3):e244-e245. doi: 10.1016/S2214-109X(18)30036-6. No abstract available.

32.

Hepatotoxicity During Isoniazid Preventive Therapy and Antiretroviral Therapy in People Living With HIV With Severe Immunosuppression: A Secondary Analysis of a Multi-Country Open-Label Randomized Controlled Clinical Trial.

Ngongondo M, Miyahara S, Hughes MD, Sun X, Bisson GP, Gupta A, Kumwenda J, Lavenberg JA, Torres TS, Nyirenda M, Kidonge KK, Hosseinipour MC; AIDS Clinical Trials Group A5274 (REMEMBER) Study Team.

J Acquir Immune Defic Syndr. 2018 May 1;78(1):54-61. doi: 10.1097/QAI.0000000000001641.

33.

Household air pollution, chronic respiratory disease and pneumonia in Malawian adults: A case-control study.

Jary HR, Aston S, Ho A, Giorgi E, Kalata N, Nyirenda M, Mallewa J, Peterson I, Gordon SB, Mortimer K.

Wellcome Open Res. 2017 Oct 24;2:103. doi: 10.12688/wellcomeopenres.12621.1. eCollection 2017.

34.

Prevalence of obesity, hypertension, and diabetes, and cascade of care in sub-Saharan Africa: a cross-sectional, population-based study in rural and urban Malawi.

Price AJ, Crampin AC, Amberbir A, Kayuni-Chihana N, Musicha C, Tafatatha T, Branson K, Lawlor DA, Mwaiyeghele E, Nkhwazi L, Smeeth L, Pearce N, Munthali E, Mwagomba BM, Mwansambo C, Glynn JR, Jaffar S, Nyirenda M.

Lancet Diabetes Endocrinol. 2018 Mar;6(3):208-222. doi: 10.1016/S2213-8587(17)30432-1. Epub 2018 Jan 19.

35.

As-Needed Vs Immediate Etoposide Chemotherapy in Combination With Antiretroviral Therapy for Mild-to-Moderate AIDS-Associated Kaposi Sarcoma in Resource-Limited Settings: A5264/AMC-067 Randomized Clinical Trial.

Hosseinipour MC, Kang M, Krown SE, Bukuru A, Umbleja T, Martin JN, Orem J, Godfrey C, Hoagland B, Mwelase N, Langat D, Nyirenda M, MacRae J, Borok M, Samaneka W, Moses A, Mngqbisa R, Busakhala N, Martínez-Maza O, Ambinder R, Dittmer DP, Nokta M, Campbell TB; A5264/AMC-067 REACT-KS Team.

Clin Infect Dis. 2018 Jul 2;67(2):251-260. doi: 10.1093/cid/ciy044.

36.

Patterns of adult body mass in sub-Saharan Africa.

Nyirenda MJ, Ramsay M, Byass P.

Glob Health Action. 2018;11(sup2):1556497. doi: 10.1080/16549716.2018.1556497. No abstract available.

37.
38.

Impact of Human Immunodeficiency Virus on the Burden and Severity of Influenza Illness in Malawian Adults: A Prospective Cohort and Parallel Case-Control Study.

Ho A, Aston SJ, Jary H, Mitchell T, Alaerts M, Menyere M, Mallewa J, Nyirenda M, Everett D, Heyderman RS, French N.

Clin Infect Dis. 2018 Mar 5;66(6):865-876. doi: 10.1093/cid/cix903.

39.

The added value of a mobile application of Community Case Management on referral, re-consultation and hospitalization rates of children aged under 5 years in two districts in Northern Malawi: study protocol for a pragmatic, stepped-wedge cluster-randomized controlled trial.

Hardy V, O'Connor Y, Heavin C, Mastellos N, Tran T, O'Donoghue J, Fitzpatrick AL, Ide N, Wu TJ, Chirambo GB, Muula AS, Nyirenda M, Carlsson S, Andersson B, Thompson M.

Trials. 2017 Oct 11;18(1):475. doi: 10.1186/s13063-017-2213-z.

40.

Prevalent Herpes Simplex Virus-2 Increases the Risk of Incident Bacterial Vaginosis in Women from South Africa.

Abbai NS, Nyirenda M, Naidoo S, Ramjee G.

AIDS Behav. 2018 Jul;22(7):2172-2180. doi: 10.1007/s10461-017-1924-1.

41.

Comparison of Hepatitis B Virus Infection in HIV-Infected and HIV-Uninfected Participants Enrolled in a Multinational Clinical Trial: HPTN 052.

Greer AE, Ou SS, Wilson E, Piwowar-Manning E, Forman MS, McCauley M, Gamble T, Ruangyuttikarn C, Hosseinipour MC, Kumarasamy N, Nyirenda M, Grinsztejn B, Pilotto JH, Kosashunhanan N, Gonçalves de Melo M, Makhema J, Akelo V, Panchia R, Badal-Faesen S, Chen YQ, Cohen MS, Eshleman SH, Thio CL, Valsamakis A.

J Acquir Immune Defic Syndr. 2017 Dec 1;76(4):388-393. doi: 10.1097/QAI.0000000000001511.

42.

Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod.

Ghadiri M, Fitz-Gerald L, Rezk A, Li R, Nyirenda M, Haegert D, Giacomini PS, Bar-Or A, Antel J.

Mult Scler. 2017 Aug;23(9):1225-1232. doi: 10.1177/1352458517713147.

PMID:
28749311
43.

Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations.

Norris SA, Daar A, Balasubramanian D, Byass P, Kimani-Murage E, Macnab A, Pauw C, Singhal A, Yajnik C, Akazili J, Levitt N, Maatoug J, Mkhwanazi N, Moore SE, Nyirenda M, Pulliam JRC, Rochat T, Said-Mohamed R, Seedat S, Sobngwi E, Tomlinson M, Toska E, van Schalkwyk C.

Glob Health Action. 2017;10(1):1334985. doi: 10.1080/16549716.2017.1334985.

44.

Diabetes in sub-Saharan Africa: from clinical care to health policy.

Atun R, Davies JI, Gale EAM, Bärnighausen T, Beran D, Kengne AP, Levitt NS, Mangugu FW, Nyirenda MJ, Ogle GD, Ramaiya K, Sewankambo NK, Sobngwi E, Tesfaye S, Yudkin JS, Basu S, Bommer C, Heesemann E, Manne-Goehler J, Postolovska I, Sagalova V, Vollmer S, Abbas ZG, Ammon B, Angamo MT, Annamreddi A, Awasthi A, Besançon S, Bhadriraju S, Binagwaho A, Burgess PI, Burton MJ, Chai J, Chilunga FP, Chipendo P, Conn A, Joel DR, Eagan AW, Gishoma C, Ho J, Jong S, Kakarmath SS, Khan Y, Kharel R, Kyle MA, Lee SC, Lichtman A, Malm CP, Mbaye MN, Muhimpundu MA, Mwagomba BM, Mwangi KJ, Nair M, Niyonsenga SP, Njuguna B, Okafor OLO, Okunade O, Park PH, Pastakia SD, Pekny C, Reja A, Rotimi CN, Rwunganira S, Sando D, Sarriera G, Sharma A, Sidibe A, Siraj ES, Syed AS, Van Acker K, Werfalli M.

Lancet Diabetes Endocrinol. 2017 Aug;5(8):622-667. doi: 10.1016/S2213-8587(17)30181-X. Epub 2017 Jul 5. Review. No abstract available.

PMID:
28688818
45.

Herpes Simplex Virus Type 2 Acquisition Among HIV-1-Infected Adults Treated With Tenofovir Disoproxyl Fumarate as Part of Combination Antiretroviral Therapy: Results From the ACTG A5175 PEARLS Study.

Celum C, Hong T, Cent A, Donnell D, Morrow R, Baeten JM, Firnhaber C, Grinsztejn B, Hosseinipour MC, Lalloo U, Nyirenda M, Riviere C, Sanchez J, Santos B, Supparatpinyo K, Hakim J, Kumarasamy N, Campbell TB; ACTG PEARLS/A5175 Team.

J Infect Dis. 2017 Mar 15;215(6):907-910. doi: 10.1093/infdis/jix029.

46.

Long-term effects of severe acute malnutrition on lung function in Malawian children: a cohort study.

Lelijveld N, Kerac M, Seal A, Chimwezi E, Wells JC, Heyderman RS, Nyirenda MJ, Stocks J, Kirkby J.

Eur Respir J. 2017 Apr 5;49(4). pii: 1601301. doi: 10.1183/13993003.01301-2016. Print 2017 Apr.

47.

Prevalence and risk factors for anemia severity and type in Malawian men and women: urban and rural differences.

Adamu AL, Crampin A, Kayuni N, Amberbir A, Koole O, Phiri A, Nyirenda M, Fine P.

Popul Health Metr. 2017 Mar 29;15(1):12. doi: 10.1186/s12963-017-0128-2.

48.

Off-licence use of once-daily maraviroc in children and adolescents with perinatally acquired HIV-1 infection.

Fraser-Taliente T, Mackie NE, Kaye S, Nyirenda M, Foster C.

HIV Med. 2017 Apr;18(4):311-313. doi: 10.1111/hiv.12467. Epub 2016 Dec 16. No abstract available.

49.

The burden of hypertension, diabetes mellitus, and cardiovascular risk factors among adult Malawians in HIV care: consequences for integrated services.

Divala OH, Amberbir A, Ismail Z, Beyene T, Garone D, Pfaff C, Singano V, Akello H, Joshua M, Nyirenda MJ, Matengeni A, Berman J, Mallewa J, Chinomba GS, Kayange N, Allain TJ, Chan AK, Sodhi SK, van Oosterhout JJ.

BMC Public Health. 2016 Dec 12;16(1):1243.

50.

A cleaner burning biomass-fuelled cookstove intervention to prevent pneumonia in children under 5 years old in rural Malawi (the Cooking and Pneumonia Study): a cluster randomised controlled trial.

Mortimer K, Ndamala CB, Naunje AW, Malava J, Katundu C, Weston W, Havens D, Pope D, Bruce NG, Nyirenda M, Wang D, Crampin A, Grigg J, Balmes J, Gordon SB.

Lancet. 2017 Jan 14;389(10065):167-175. doi: 10.1016/S0140-6736(16)32507-7. Epub 2016 Dec 7.

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