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Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019.

Hammerum AM, Justesen US, Pinholt M, Roer L, Kaya H, Worning P, Nygaard S, Kemp M, Clausen ME, Nielsen KL, Samulioniené J, Kjærsgaard M, Østergaard C, Coia J, Søndergaard TS, Gaini S, Schønning K, Westh H, Hasman H, Holzknecht BJ.

Euro Surveill. 2019 Aug;24(34). doi: 10.2807/1560-7917.ES.2019.24.34.1900503.


Autonomic cardiovascular control changes in recent heart transplant recipients lead to physiological limitations in response to orthostatic challenge and isometric exercise.

Nygaard S, Christensen AH, Rolid K, Nytrøen K, Gullestad L, Fiane A, Thaulow E, Døhlen G, Godang K, Saul JP, Wyller VBB.

Eur J Appl Physiol. 2019 Aug 12. doi: 10.1007/s00421-019-04207-5. [Epub ahead of print]


Diagnosing adenomyosis with MRI: a prospective study revisiting the junctional zone thickness cutoff of 12 mm as a diagnostic marker.

Tellum T, Matic GV, Dormagen JB, Nygaard S, Viktil E, Qvigstad E, Lieng M.

Eur Radiol. 2019 Jul 1. doi: 10.1007/s00330-019-06308-3. [Epub ahead of print]


Are Low-to-Moderate Average Alcohol Consumption and Isolated Episodes of Binge Drinking in Early Pregnancy Associated with Facial Features Related to Fetal Alcohol Syndrome in 5-Year-Old Children?

Kesmodel US, Nygaard SS, Mortensen EL, Bertrand J, Denny CH, Glidewell A, Astley Hemingway S.

Alcohol Clin Exp Res. 2019 Jun;43(6):1199-1212. doi: 10.1111/acer.14047. Epub 2019 May 24.


Exploring motivations, attitudes and experiences of oocyte donors: A qualitative study.

Borgstrøm MB, Nygaard SS, Danielsen AK, Kesmodel US.

Acta Obstet Gynecol Scand. 2019 Aug;98(8):1055-1062. doi: 10.1111/aogs.13583. Epub 2019 Mar 18.


Development of a clinical prediction model for diagnosing adenomyosis.

Tellum T, Nygaard S, Skovholt EK, Qvigstad E, Lieng M.

Fertil Steril. 2018 Oct;110(5):957-964.e3. doi: 10.1016/j.fertnstert.2018.06.009.


Home births-Where are we heading?

Nygaard SS, Kesmodel US.

Acta Obstet Gynecol Scand. 2018 Oct;97(10):1155-1156. doi: 10.1111/aogs.13441. No abstract available.


Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA.

Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25.


Biodistribution and Dosimetry Results from a Phase 1 Trial of Therapy with the Antibody-Radionuclide Conjugate 177Lu-Lilotomab Satetraxetan.

Blakkisrud J, Holtedahl JE, Løndalen A, Dahle J, Bach-Gansmo T, Holte H, Nygaard S, Kolstad A, Stokke C.

J Nucl Med. 2018 Apr;59(4):704-710. doi: 10.2967/jnumed.117.195347. Epub 2017 Aug 28.


Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents.

Waller JA, Nygaard SH, Li Y, du Jardin KG, Tamm JA, Abdourahman A, Elfving B, Pehrson AL, Sánchez C, Wernersson R.

BMC Neurosci. 2017 Aug 4;18(1):56. doi: 10.1186/s12868-017-0376-x.


Antibodies to Signaling Molecules and Receptors in Alzheimer's Disease are Associated with Psychomotor Slowing, Depression, and Poor Visuospatial Function.

Giil LM, Vedeler CA, Kristoffersen EK, Nordrehaug JE, Heidecke H, Dechend R, Schulze-Forster K, Muller DN, von Goetze VS, Cabral-Marques O, Riemekasten G, Vogelsang P, Nygaard S, Lund A, Aarsland D.

J Alzheimers Dis. 2017;59(3):929-939. doi: 10.3233/JAD-170245.


Reciprocal genomic evolution in the ant-fungus agricultural symbiosis.

Nygaard S, Hu H, Li C, Schiøtt M, Chen Z, Yang Z, Xie Q, Ma C, Deng Y, Dikow RB, Rabeling C, Nash DR, Wcislo WT, Brady SG, Schultz TR, Zhang G, Boomsma JJ.

Nat Commun. 2016 Jul 20;7:12233. doi: 10.1038/ncomms12233.


A universal system to select gene-modified hepatocytes in vivo.

Nygaard S, Barzel A, Haft A, Major A, Finegold M, Kay MA, Grompe M.

Sci Transl Med. 2016 Jun 8;8(342):342ra79. doi: 10.1126/scitranslmed.aad8166.


Personal Metabolism (PM) coupled with Life Cycle Assessment (LCA) model: Danish Case Study.

Kalbar PP, Birkved M, Kabins S, Nygaard SE.

Environ Int. 2016 May;91:168-79. doi: 10.1016/j.envint.2016.02.032. Epub 2016 Mar 11.


DivA: detection of non-homologous and very divergent regions in protein sequence alignments.

Zepeda Mendoza ML, Nygaard S, da Fonseca RR.

BMC Res Notes. 2014 Nov 18;7:806. doi: 10.1186/1756-0500-7-806.


Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior.

Li Q, Wang Z, Lian J, Schiøtt M, Jin L, Zhang P, Zhang Y, Nygaard S, Peng Z, Zhou Y, Deng Y, Zhang W, Boomsma JJ, Zhang G.

Nat Commun. 2014 Sep 30;5:4943. doi: 10.1038/ncomms5943.


Complementary symbiont contributions to plant decomposition in a fungus-farming termite.

Poulsen M, Hu H, Li C, Chen Z, Xu L, Otani S, Nygaard S, Nobre T, Klaubauf S, Schindler PM, Hauser F, Pan H, Yang Z, Sonnenberg AS, de Beer ZW, Zhang Y, Wingfield MJ, Grimmelikhuijzen CJ, de Vries RP, Korb J, Aanen DK, Wang J, Boomsma JJ, Zhang G.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14500-5. doi: 10.1073/pnas.1319718111. Epub 2014 Sep 22.


Exogenous metallothionein potentiates the insulin response at normal glucose concentrations in INS-1E beta-cells without disturbing intracellular ZnT8 expression.

Nygaard SB, Lund NS, Larsen A, Pedersen N, Rungby J, Smidt K.

Basic Clin Pharmacol Toxicol. 2015 Feb;116(2):173-7. doi: 10.1111/bcpt.12287. Epub 2014 Aug 28. No abstract available.


Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells.

Nygaard SB, Larsen A, Knuhtsen A, Rungby J, Smidt K.

BMC Res Notes. 2014 Feb 7;7:84. doi: 10.1186/1756-0500-7-84.


Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Lisowski L, Dane AP, Chu K, Zhang Y, Cunningham SC, Wilson EM, Nygaard S, Grompe M, Alexander IE, Kay MA.

Nature. 2014 Feb 20;506(7488):382-6. doi: 10.1038/nature12875. Epub 2013 Dec 25.


The fungal symbiont of Acromyrmex leaf-cutting ants expresses the full spectrum of genes to degrade cellulose and other plant cell wall polysaccharides.

Grell MN, Linde T, Nygaard S, Nielsen KL, Boomsma JJ, Lange L.

BMC Genomics. 2013 Dec 28;14:928. doi: 10.1186/1471-2164-14-928.


Real-time monitoring of lycopene content in tomato-derived products during processing: implementation of a novel double-slit Raman spectrometer.

Køcks M, Banke SO, Madsen B, Vaz T, Carvalheira M, Pandega N, Sousa I, Nygaard SD.

Appl Spectrosc. 2013 Jun;67(6):681-7. doi: 10.1366/12-06813.


Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality.

Simola DF, Wissler L, Donahue G, Waterhouse RM, Helmkampf M, Roux J, Nygaard S, Glastad KM, Hagen DE, Viljakainen L, Reese JT, Hunt BG, Graur D, Elhaik E, Kriventseva EV, Wen J, Parker BJ, Cash E, Privman E, Childers CP, Muñoz-Torres MC, Boomsma JJ, Bornberg-Bauer E, Currie CR, Elsik CG, Suen G, Goodisman MA, Keller L, Liebig J, Rawls A, Reinberg D, Smith CD, Smith CR, Tsutsui N, Wurm Y, Zdobnov EM, Berger SL, Gadau J.

Genome Res. 2013 Aug;23(8):1235-47. doi: 10.1101/gr.155408.113. Epub 2013 May 1.


Laccase detoxification mediates the nutritional alliance between leaf-cutting ants and fungus-garden symbionts.

De Fine Licht HH, Schiøtt M, Rogowska-Wrzesinska A, Nygaard S, Roepstorff P, Boomsma JJ.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):583-7. doi: 10.1073/pnas.1212709110. Epub 2012 Dec 24.


Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors.

Fortin DA, Srivastava T, Dwarakanath D, Pierre P, Nygaard S, Derkach VA, Soderling TR.

J Neurosci. 2012 Jun 13;32(24):8127-37. doi: 10.1523/JNEUROSCI.6034-11.2012.


Regulation of neuronal mRNA translation by CaM-kinase I phosphorylation of eIF4GII.

Srivastava T, Fortin DA, Nygaard S, Kaech S, Sonenberg N, Edelman AM, Soderling TR.

J Neurosci. 2012 Apr 18;32(16):5620-30. doi: 10.1523/JNEUROSCI.0030-12.2012.


Old soldiers never die ....

Boomsma JJ, Nygaard S.

Genome Biol. 2012 Feb 22;13(2):144. doi: 10.1186/gb-2012-13-2-144.


The genomic impact of 100 million years of social evolution in seven ant species.

Gadau J, Helmkampf M, Nygaard S, Roux J, Simola DF, Smith CR, Suen G, Wurm Y, Smith CD.

Trends Genet. 2012 Jan;28(1):14-21. doi: 10.1016/j.tig.2011.08.005. Epub 2011 Oct 5. Review.


The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming.

Nygaard S, Zhang G, Schiøtt M, Li C, Wurm Y, Hu H, Zhou J, Ji L, Qiu F, Rasmussen M, Pan H, Hauser F, Krogh A, Grimmelikhuijzen CJ, Wang J, Boomsma JJ.

Genome Res. 2011 Aug;21(8):1339-48. doi: 10.1101/gr.121392.111. Epub 2011 Jun 30.


Microbial growth studies in biodiesel blends.

Sørensen G, Pedersen DV, Nørgaard AK, Sørensen KB, Nygaard SD.

Bioresour Technol. 2011 Apr;102(8):5259-64. doi: 10.1016/j.biortech.2011.02.017. Epub 2011 Feb 13.


The genome of the fire ant Solenopsis invicta.

Wurm Y, Wang J, Riba-Grognuz O, Corona M, Nygaard S, Hunt BG, Ingram KK, Falquet L, Nipitwattanaphon M, Gotzek D, Dijkstra MB, Oettler J, Comtesse F, Shih CJ, Wu WJ, Yang CC, Thomas J, Beaudoing E, Pradervand S, Flegel V, Cook ED, Fabbretti R, Stockinger H, Long L, Farmerie WG, Oakey J, Boomsma JJ, Pamilo P, Yi SV, Heinze J, Goodisman MA, Farinelli L, Harshman K, Hulo N, Cerutti L, Xenarios I, Shoemaker D, Keller L.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5679-84. doi: 10.1073/pnas.1009690108. Epub 2011 Jan 31.


Take Heart America: A comprehensive, community-wide, systems-based approach to the treatment of cardiac arrest.

Lick CJ, Aufderheide TP, Niskanen RA, Steinkamp JE, Davis SP, Nygaard SD, Bemenderfer KK, Gonzales L, Kalla JA, Wald SK, Gillquist DL, Sayre MR, Osaki Holm SY, Oakes DA, Provo TA, Racht EM, Olsen JD, Yannopoulos D, Lurie KG.

Crit Care Med. 2011 Jan;39(1):26-33. doi: 10.1097/CCM.0b013e3181fa7ce4. Erratum in: Crit Care Med. 2011 Apr;39(4):930. Oski Holm, Susie Y [corrected to Osaki Holm, Susie Y].


Long- and short-term selective forces on malaria parasite genomes.

Nygaard S, Braunstein A, Malsen G, Van Dongen S, Gardner PP, Krogh A, Otto TD, Pain A, Berriman M, McAuliffe J, Dermitzakis ET, Jeffares DC.

PLoS Genet. 2010 Sep 9;6(9):e1001099. doi: 10.1371/journal.pgen.1001099.


Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I.

Fortin DA, Davare MA, Srivastava T, Brady JD, Nygaard S, Derkach VA, Soderling TR.

J Neurosci. 2010 Sep 1;30(35):11565-75. doi: 10.1523/JNEUROSCI.1746-10.2010.


Transient receptor potential canonical 5 channels activate Ca2+/calmodulin kinase Igamma to promote axon formation in hippocampal neurons.

Davare MA, Fortin DA, Saneyoshi T, Nygaard S, Kaech S, Banker G, Soderling TR, Wayman GA.

J Neurosci. 2009 Aug 5;29(31):9794-808. doi: 10.1523/JNEUROSCI.1544-09.2009.


Determination of binding strengths of a host-guest complex using resonance Raman scattering.

Witlicki EH, Hansen SW, Christensen M, Hansen TS, Nygaard SD, Jeppesen JO, Wong EW, Jensen L, Flood AH.

J Phys Chem A. 2009 Aug 27;113(34):9450-7. doi: 10.1021/jp905202x. Epub 2009 Jul 31.


Cardiac troponin I degradation in serum of patients with hypertrophic obstructive cardiomyopathy undergoing percutaneous septal ablation.

Madsen LH, Lund T, Grieg Z, Nygaard S, Holmvang L, Jurlander B, Grande P, Christensen G, Atar D.

Cardiology. 2009;114(3):167-73. doi: 10.1159/000226596. Epub 2009 Jul 2.


Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing.

Nygaard S, Jacobsen A, Lindow M, Eriksen J, Balslev E, Flyger H, Tolstrup N, Møller S, Krogh A, Litman T.

BMC Med Genomics. 2009 Jun 9;2:35. doi: 10.1186/1755-8794-2-35.


The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

FANTOM Consortium, Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, Kanamori-Katayama M, Kubosaki A, Akalin A, Ando Y, Arner E, Asada M, Asahara H, Bailey T, Bajic VB, Bauer D, Beckhouse AG, Bertin N, Björkegren J, Brombacher F, Bulger E, Chalk AM, Chiba J, Cloonan N, Dawe A, Dostie J, Engström PG, Essack M, Faulkner GJ, Fink JL, Fredman D, Fujimori K, Furuno M, Gojobori T, Gough J, Grimmond SM, Gustafsson M, Hashimoto M, Hashimoto T, Hatakeyama M, Heinzel S, Hide W, Hofmann O, Hörnquist M, Huminiecki L, Ikeo K, Imamoto N, Inoue S, Inoue Y, Ishihara R, Iwayanagi T, Jacobsen A, Kaur M, Kawaji H, Kerr MC, Kimura R, Kimura S, Kimura Y, Kitano H, Koga H, Kojima T, Kondo S, Konno T, Krogh A, Kruger A, Kumar A, Lenhard B, Lennartsson A, Lindow M, Lizio M, Macpherson C, Maeda N, Maher CA, Maqungo M, Mar J, Matigian NA, Matsuda H, Mattick JS, Meier S, Miyamoto S, Miyamoto-Sato E, Nakabayashi K, Nakachi Y, Nakano M, Nygaard S, Okayama T, Okazaki Y, Okuda-Yabukami H, Orlando V, Otomo J, Pachkov M, Petrovsky N, Plessy C, Quackenbush J, Radovanovic A, Rehli M, Saito R, Sandelin A, Schmeier S, Schönbach C, Schwartz AS, Semple CA, Sera M, Severin J, Shirahige K, Simons C, St Laurent G, Suzuki M, Suzuki T, Sweet MJ, Taft RJ, Takeda S, Takenaka Y, Tan K, Taylor MS, Teasdale RD, Tegnér J, Teichmann S, Valen E, Wahlestedt C, Waki K, Waterhouse A, Wells CA, Winther O, Wu L, Yamaguchi K, Yanagawa H, Yasuda J, Zavolan M, Hume DA; Riken Omics Science Center, Arakawa T, Fukuda S, Imamura K, Kai C, Kaiho A, Kawashima T, Kawazu C, Kitazume Y, Kojima M, Miura H, Murakami K, Murata M, Ninomiya N, Nishiyori H, Noma S, Ogawa C, Sano T, Simon C, Tagami M, Takahashi Y, Kawai J, Hayashizaki Y.

Nat Genet. 2009 May;41(5):553-62. doi: 10.1038/ng.375. Epub 2009 Apr 19.


Spontaneous prenatal ductal closure: postnatal diagnosis?

Nygaard SI, Petersen OB, Garne E, Sørensen KE.

Pediatr Cardiol. 2009 Feb;30(2):176-80. doi: 10.1007/s00246-008-9269-1. Epub 2008 Sep 9.


Structure-property relationships in redox-gated single molecule junctions--a comparison of pyrrolo-tetrathiafulvalene and viologen redox groups.

Leary E, Higgins SJ, van Zalinge H, Haiss W, Nichols RJ, Nygaard S, Jeppesen JO, Ulstrup J.

J Am Chem Soc. 2008 Sep 17;130(37):12204-5. doi: 10.1021/ja8014605. Epub 2008 Aug 23.


[Medical emergency care and patient contact at the Quart Rock Festival in Norway].

Skjeie H, Nygaard S, Li HS, Gardasevic B, Fetveit A, Brekke M.

Tidsskr Nor Laegeforen. 2008 Jun 26;128(13):1508-11. Norwegian.


Intragenomic matching reveals a huge potential for miRNA-mediated regulation in plants.

Lindow M, Jacobsen A, Nygaard S, Mang Y, Krogh A.

PLoS Comput Biol. 2007 Nov;3(11):e238.


Preparation of cyclobis(paraquat-p-phenylene)-based [2]rotaxanes without flexible glycol chains.

Nygaard S, Laursen BW, Hansen TS, Bond AD, Flood AH, Jeppesen JO.

Angew Chem Int Ed Engl. 2007;46(32):6093-7. No abstract available.


Two classes of alongside charge-transfer interactions defined in one [2]catenane.

Nygaard S, Hansen SW, Huffman JC, Jensen F, Flood AH, Jeppesen JO.

J Am Chem Soc. 2007 Jun 13;129(23):7354-63. Epub 2007 May 18.


Binding studies between triethylene glycol-substituted monopyrrolotetrathiafulvalene derivatives and cyclobis(paraquat-p-phenylene).

Nygaard S, Hansen CN, Jeppesen JO.

J Org Chem. 2007 Mar 2;72(5):1617-26. Epub 2007 Jan 27.


Functionally rigid bistable [2]rotaxanes.

Nygaard S, Leung KC, Aprahamian I, Ikeda T, Saha S, Laursen BW, Kim SY, Hansen SW, Stein PC, Flood AH, Stoddart JF, Jeppesen JO.

J Am Chem Soc. 2007 Jan 31;129(4):960-70.


Cis- and trans-bis(2-cyanoethylsulfanyl)(decane-1,10-diyldithio)tetrathiafulvalene.

Nygaard S, Flood AH, Jeppesen JO, Bond AD.

Acta Crystallogr C. 2006 Dec;62(Pt 12):o677-80. Epub 2006 Nov 10.


Locking down the electronic structure of (monopyrrolo)tetrathiafulvalene in [2]rotaxanes.

Flood AH, Nygaard S, Laursen BW, Jeppesen JO, Stoddart JF.

Org Lett. 2006 May 25;8(11):2205-8.


Atlantic salmon paramyxovirus (ASPV) infection contributes to proliferative gill inflammation (PGI) in seawater-reared Salmo salar.

Kvellestad A, Falk K, Nygaard SM, Flesja K, Holm JA.

Dis Aquat Organ. 2005 Nov 9;67(1-2):47-54.

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