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Items: 1 to 50 of 107

1.

Danish study of Non-Invasive testing in Coronary Artery Disease 2 (Dan-NICAD 2): Study design for a controlled study of diagnostic accuracy.

Rasmussen LD, Winther S, Westra J, Isaksen C, Ejlersen JA, Brix L, Kirk J, Urbonaviciene G, Søndergaard HM, Hammid O, Schmidt SE, Knudsen LL, Madsen LH, Frost L, Petersen SE, Gormsen LC, Christiansen EH, Eftekhari A, Holm NR, Nyegaard M, Chiribiri A, Bøtker HE, Böttcher M.

Am Heart J. 2019 May 1;215:114-128. doi: 10.1016/j.ahj.2019.03.016. [Epub ahead of print]

PMID:
31323454
2.

The International Calmodulinopathy Registry: recording the diverse phenotypic spectrum of un-CALM hearts.

Nyegaard M, Overgaard MT.

Eur Heart J. 2019 Jul 5. pii: ehz463. doi: 10.1093/eurheartj/ehz463. [Epub ahead of print] No abstract available.

PMID:
31280324
3.

Genome-wide association study implicates CHRNA2 in cannabis use disorder.

Demontis D, Rajagopal VM, Thorgeirsson TE, Als TD, Grove J, Leppälä K, Gudbjartsson DF, Pallesen J, Hjorthøj C, Reginsson GW, Tyrfingsson T, Runarsdottir V, Qvist P, Christensen JH, Bybjerg-Grauholm J, Bækvad-Hansen M, Huckins LM, Stahl EA, Timmermann A, Agerbo E, Hougaard DM, Werge T, Mors O, Mortensen PB, Nordentoft M, Daly MJ, Stefansson H, Stefansson K, Nyegaard M, Børglum AD.

Nat Neurosci. 2019 Jul;22(7):1066-1074. doi: 10.1038/s41593-019-0416-1. Epub 2019 Jun 17.

PMID:
31209380
4.

DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors.

Hansen TF, Banasik K, Erikstrup C, Pedersen OB, Westergaard D, Chmura PJ, Nielsen K, Thørner L, Hjalgrim H, Paarup H, Larsen MAH, Petersen M, Jennum P, Andersen S, Nyegaard M, Jemec GBE, Olesen J, Werge T, Johansson PI, Sørensen E, Brunak S, Ullum H, Burgdorf KS.

BMJ Open. 2019 Jun 9;9(6):e028401. doi: 10.1136/bmjopen-2018-028401.

5.

The ABO locus is associated with increased platelet aggregation in patients with stable coronary artery disease.

Christiansen MK, Larsen SB, Nyegaard M, Neergaard-Petersen S, Würtz M, Grove EL, Hvas AM, Jensen HK, Kristensen SD.

Int J Cardiol. 2019 Jul 1;286:152-158. doi: 10.1016/j.ijcard.2019.01.090. Epub 2019 Feb 11.

PMID:
30837090
6.

Identification of common genetic risk variants for autism spectrum disorder.

Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, Nærland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnström K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, Børglum AD.

Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038/s41588-019-0344-8. Epub 2019 Feb 25.

7.

HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA.

Madsen P, Isaksen TJ, Siupka P, Tóth AE, Nyegaard M, Gustafsen C, Nielsen MS.

Sci Rep. 2019 Jan 24;9(1):611. doi: 10.1038/s41598-018-37336-6.

8.

Human Calmodulin Mutations.

Jensen HH, Brohus M, Nyegaard M, Overgaard MT.

Front Mol Neurosci. 2018 Nov 13;11:396. doi: 10.3389/fnmol.2018.00396. eCollection 2018.

9.
10.

Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function.

Laustsen A, Bak RO, Krapp C, Kjær L, Egedahl JH, Petersen CC, Pillai S, Tang HQ, Uldbjerg N, Porteus M, Roan NR, Nyegaard M, Denton PW, Jakobsen MR.

Nat Commun. 2018 Aug 30;9(1):3525. doi: 10.1038/s41467-018-05816-y.

11.

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming.

Olagnier D, Brandtoft AM, Gunderstofte C, Villadsen NL, Krapp C, Thielke AL, Laustsen A, Peri S, Hansen AL, Bonefeld L, Thyrsted J, Bruun V, Iversen MB, Lin L, Artegoitia VM, Su C, Yang L, Lin R, Balachandran S, Luo Y, Nyegaard M, Marrero B, Goldbach-Mansky R, Motwani M, Ryan DG, Fitzgerald KA, O'Neill LA, Hollensen AK, Damgaard CK, de Paoli FV, Bertram HC, Jakobsen MR, Poulsen TB, Holm CK.

Nat Commun. 2018 Aug 29;9(1):3506. doi: 10.1038/s41467-018-05861-7.

12.

Association between circulating proprotein convertase subtilisin/kexin type 9 levels and prognosis in patients with severe chronic kidney disease.

Rasmussen LD, Bøttcher M, Ivarsen P, Jørgensen HS, Nyegaard M, Buttenschøn H, Gustafsen C, Glerup S, Bøtker HE, Svensson M, Winther S.

Nephrol Dial Transplant. 2018 Aug 22. doi: 10.1093/ndt/gfy257. [Epub ahead of print]

PMID:
30137516
13.

Global transcriptional changes in response to cGAMP depend on STING in human THP-1 cells.

Hansen AL, Brandtoft AM, Nyegaard M, Thielke AL, Olagnier D, Holm CK.

Cell Mol Immunol. 2018 Nov;15(11):983-985. doi: 10.1038/s41423-018-0035-x. Epub 2018 May 16. No abstract available.

PMID:
29769658
14.

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins.

Starnawska A, Tan Q, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.

Front Aging Neurosci. 2017 Dec 12;9:413. doi: 10.3389/fnagi.2017.00413. eCollection 2017.

15.

Biological age of the endometrium using DNA methylation.

Olesen MS, Starnawska A, Bybjerg-Grauholm J, Bielfeld AP, Agerholm I, Forman A, Overgaard MT, Nyegaard M.

Reproduction. 2018 Feb;155(2):167-172. doi: 10.1530/REP-17-0601. Epub 2017 Nov 21.

PMID:
29162648
16.

Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry.

Sapkota Y, Vivo I, Steinthorsdottir V, Fassbender A, Bowdler L, Buring JE, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, Thorleifsson G, Wallace LM; iPSYCH-SSI-Broad Group, Kraft P, Morris AP, Nyholt DR, Edwards DRV, Nyegaard M, D'Hooghe T, Chasman DI, Stefansson K, Missmer SA, Montgomery GW.

Sci Rep. 2017 Sep 12;7(1):11380. doi: 10.1038/s41598-017-10440-9.

17.

The SH2B3 and KCNK5 loci may be implicated in regulation of platelet count, volume, and maturity.

Christiansen MK, Larsen SB, Nyegaard M, Neergaard-Petersen S, Würtz M, Grove EL, Hvas AM, Jensen HK, Kristensen SD.

Thromb Res. 2017 Oct;158:86-92. doi: 10.1016/j.thromres.2017.08.009. Epub 2017 Aug 18.

PMID:
28865245
18.

Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome.

Starnawska A, Hansen CS, Sparsø T, Mazin W, Olsen L, Bertalan M, Buil A, Bybjerg-Grauholm J, Bækvad-Hansen M, Hougaard DM, Mortensen PB, Pedersen CB, Nyegaard M, Werge T, Weinsheimer S.

Transl Psychiatry. 2017 Aug 29;7(8):e1221. doi: 10.1038/tp.2017.181.

19.

Coronary artery disease-associated genetic variants and biomarkers of inflammation.

Christiansen MK, Larsen SB, Nyegaard M, Neergaard-Petersen S, Ajjan R, Würtz M, Grove EL, Hvas AM, Jensen HK, Kristensen SD.

PLoS One. 2017 Jul 7;12(7):e0180365. doi: 10.1371/journal.pone.0180365. eCollection 2017.

20.

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.

Sapkota Y, Steinthorsdottir V, Morris AP, Fassbender A, Rahmioglu N, De Vivo I, Buring JE, Zhang F, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, MacGregor S, Martin NG, Becker CM, Adachi S, Yoshihara K, Enomoto T, Takahashi A, Kamatani Y, Matsuda K, Kubo M, Thorleifsson G, Geirsson RT, Thorsteinsdottir U, Wallace LM; iPSYCH-SSI-Broad Group, Yang J, Velez Edwards DR, Nyegaard M, Low SK, Zondervan KT, Missmer SA, D'Hooghe T, Montgomery GW, Chasman DI, Stefansson K, Tung JY, Nyholt DR.

Nat Commun. 2017 May 24;8:15539. doi: 10.1038/ncomms15539.

21.

Squid predation by slender sunfish Ranzania laevis (Molidae).

Nyegaard M, Loneragan N, Santos MB.

J Fish Biol. 2017 Jun;90(6):2480-2487. doi: 10.1111/jfb.13315. Epub 2017 May 3.

PMID:
28470845
22.

A genetic risk score predicts cardiovascular events in patients with stable coronary artery disease.

Christiansen MK, Nyegaard M, Larsen SB, Grove EL, Würtz M, Neergaard-Petersen S, Hvas AM, Jensen HK, Kristensen SD.

Int J Cardiol. 2017 Aug 15;241:411-416. doi: 10.1016/j.ijcard.2017.04.045. Epub 2017 Apr 19.

PMID:
28442232
23.

Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia.

Qvist P, Rajkumar AP, Redrobe JP, Nyegaard M, Christensen JH, Mors O, Wegener G, Didriksen M, Børglum AD.

Neurobiol Learn Mem. 2017 May;141:44-52. doi: 10.1016/j.nlm.2017.03.009. Epub 2017 Mar 21.

PMID:
28341151
24.

Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder.

Lescai F, Als TD, Li Q, Nyegaard M, Andorsdottir G, Biskopstø M, Hedemand A, Fiorentino A, O'Brien N, Jarram A, Liang J, Grove J, Pallesen J, Eickhardt E, Mattheisen M, Bolund L, Demontis D, Wang AG, McQuillin A, Mors O, Wang J, Børglum AD.

Transl Psychiatry. 2017 Feb 14;7(2):e1034. doi: 10.1038/tp.2017.3.

25.

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.

Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR.

Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391.

26.

A 45-SNP genetic risk score is increased in early-onset coronary artery disease but independent of familial disease clustering.

Christiansen MK, Nyegaard M, Pedersen LN, Larsen SB, Würtz M, Hjort J, Kristensen SD, Jensen HK.

Atherosclerosis. 2017 Feb;257:172-178. doi: 10.1016/j.atherosclerosis.2017.01.010. Epub 2017 Jan 13.

PMID:
28142076
27.

Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission.

Bødker JS, Severinsen MT, El-Galaly TC, Brøndum RF, Laursen MB, Falgreen S, Nyegaard M, Schmitz A, Jakobsen LH, Schönherz AA, Due H, Reinholdt L, Bøgsted M, Dybkær K, Johnsen HE.

Exp Hematol Oncol. 2017 Jan 11;6:3. doi: 10.1186/s40164-016-0063-0. eCollection 2017.

28.

DNA Methylation Analysis of BRD1 Promoter Regions and the Schizophrenia rs138880 Risk Allele.

Dyrvig M, Qvist P, Lichota J, Larsen K, Nyegaard M, Børglum AD, Christensen JH.

PLoS One. 2017 Jan 17;12(1):e0170121. doi: 10.1371/journal.pone.0170121. eCollection 2017.

29.

Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples.

Bak ST, Staunstrup NH, Starnawska A, Daugaard TF, Nyengaard JR, Nyegaard M, Børglum A, Mors O, Dorph-Petersen KA, Nielsen AL.

Mol Neurobiol. 2018 Jan;55(1):668-681. doi: 10.1007/s12035-016-0345-x. Epub 2016 Dec 19.

PMID:
27995571
30.

Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins.

Starnawska A, Tan Q, Lenart A, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.

Neurobiol Aging. 2017 Feb;50:60-63. doi: 10.1016/j.neurobiolaging.2016.10.025. Epub 2016 Nov 4.

PMID:
27889677
31.

The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.

Qvist P, Christensen JH, Vardya I, Rajkumar AP, Mørk A, Paternoster V, Füchtbauer EM, Pallesen J, Fryland T, Dyrvig M, Hauberg ME, Lundsberg B, Fejgin K, Nyegaard M, Jensen K, Nyengaard JR, Mors O, Didriksen M, Børglum AD.

Biol Psychiatry. 2017 Jul 1;82(1):62-76. doi: 10.1016/j.biopsych.2016.08.037. Epub 2016 Sep 15.

PMID:
27837920
32.

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.

Matrone C, Dzamko N, Madsen P, Nyegaard M, Pohlmann R, Søndergaard RV, Lassen LB, Andresen TL, Halliday GM, Jensen PH, Nielsen MS.

PLoS One. 2016 Aug 10;11(8):e0160501. doi: 10.1371/journal.pone.0160501. eCollection 2016.

33.

Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots.

Staunstrup NH, Starnawska A, Nyegaard M, Christiansen L, Nielsen AL, Børglum A, Mors O.

Clin Epigenetics. 2016 Jul 26;8:81. doi: 10.1186/s13148-016-0242-1. eCollection 2016.

34.

Characterization of memory B cells from thymus and its impact for DLBCL classification.

Bergkvist KS, Nørgaard MA, Bøgsted M, Schmitz A, Nyegaard M, Gaihede M, Bæch J, Grønholdt ML, Jensen FS, Johansen P, Urup T, El-Galaly TC, Madsen J, Bødker JS, Dybkær K, Johnsen HE.

Exp Hematol. 2016 Oct;44(10):982-990.e11. doi: 10.1016/j.exphem.2016.06.001. Epub 2016 Jun 11.

PMID:
27297329
35.

CACNA1C hypermethylation is associated with bipolar disorder.

Starnawska A, Demontis D, Pen A, Hedemand A, Nielsen AL, Staunstrup NH, Grove J, Als TD, Jarram A, O'Brien NL, Mors O, McQuillin A, Børglum AD, Nyegaard M.

Transl Psychiatry. 2016 Jun 7;6(6):e831. doi: 10.1038/tp.2016.99.

36.

Danish study of Non-Invasive testing in Coronary Artery Disease (Dan-NICAD): study protocol for a randomised controlled trial.

Nissen L, Winther S, Isaksen C, Ejlersen JA, Brix L, Urbonaviciene G, Frost L, Madsen LH, Knudsen LL, Schmidt SE, Holm NR, Maeng M, Nyegaard M, Bøtker HE, Bøttcher M.

Trials. 2016 May 26;17(1):262. doi: 10.1186/s13063-016-1388-z.

37.

Hypomethylation of FAM63B in bipolar disorder patients.

Starnawska A, Demontis D, McQuillin A, O'Brien NL, Staunstrup NH, Mors O, Nielsen AL, Børglum AD, Nyegaard M.

Clin Epigenetics. 2016 May 11;8:52. doi: 10.1186/s13148-016-0221-6. eCollection 2016.

38.

Identification of the BRD1 interaction network and its impact on mental disorder risk.

Fryland T, Christensen JH, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, Grove J, Demontis D, Blechingberg J, Ooi HS, Nyegaard M, Hauberg ME, Tommerup N, Gregersen N, Mors O, Corydon TJ, Nielsen AL, Børglum AD.

Genome Med. 2016 May 3;8(1):53. doi: 10.1186/s13073-016-0308-x.

39.

The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential.

Bieghs L, Johnsen HE, Maes K, Menu E, Van Valckenborgh E, Overgaard MT, Nyegaard M, Conover CA, Vanderkerken K, De Bruyne E.

Oncotarget. 2016 Jul 26;7(30):48732-48752. doi: 10.18632/oncotarget.8982. Review.

40.

Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients.

Bieghs L, Brohus M, Kristensen IB, Abildgaard N, Bøgsted M, Johnsen HE, Conover CA, De Bruyne E, Vanderkerken K, Overgaard MT, Nyegaard M.

PLoS One. 2016 Apr 25;11(4):e0154256. doi: 10.1371/journal.pone.0154256. eCollection 2016.

41.

Triploidy--Observations in 154 Diandric Cases.

Scholz NB, Bolund L, Nyegaard M, Faaborg L, Jørgensen MW, Lund H, Niemann I, Sunde L.

PLoS One. 2015 Nov 12;10(11):e0142545. doi: 10.1371/journal.pone.0142545. eCollection 2015.

42.

Paternal Hemizygosity in 11p15 in Mole-like Conceptuses: Two Case Reports.

Sunde L, Lund H, J Sebire N, Grove A, Fisher RA, Niemann I, Kjeldsen E, Andreasen L, Hansen ES, Bojesen A, Bolund L, Nyegaard M.

Medicine (Baltimore). 2015 Nov;94(44):e1776. doi: 10.1097/MD.0000000000001776.

43.

The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS.

Waltoft BL, Pedersen CB, Nyegaard M, Hobolth A.

BMC Med Genet. 2015 Aug 30;16:71. doi: 10.1186/s12881-015-0210-1.

44.

Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq.

Rajkumar AP, Qvist P, Lazarus R, Lescai F, Ju J, Nyegaard M, Mors O, Børglum AD, Li Q, Christensen JH.

BMC Genomics. 2015 Jul 25;16:548. doi: 10.1186/s12864-015-1767-y.

45.

A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.

Nyegaard M, Rendtorff ND, Nielsen MS, Corydon TJ, Demontis D, Starnawska A, Hedemand A, Buniello A, Niola F, Overgaard MT, Leal SM, Ahmad W, Wikman FP, Petersen KB, Crüger DG, Oostrik J, Kremer H, Tommerup N, Frödin M, Steel KP, Tranebjærg L, Børglum AD.

PLoS Genet. 2015 Jul 21;11(7):e1005386. doi: 10.1371/journal.pgen.1005386. eCollection 2015 Jul.

46.

Investigating interactions between early life stress and two single nucleotide polymorphisms in HSD11B2 on the risk of schizophrenia.

Debost JC, Petersen L, Grove J, Hedemand A, Khashan A, Henriksen T, Mors O, Hollegaard M, Hougaard D, Nyegaard M, Børglum A, Mortensen PB.

Psychoneuroendocrinology. 2015 Oct;60:18-27. doi: 10.1016/j.psyneuen.2015.05.013. Epub 2015 Jun 11.

PMID:
26115144
47.

Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models.

Falgreen S, Dybkær K, Young KH, Xu-Monette ZY, El-Galaly TC, Laursen MB, Bødker JS, Kjeldsen MK, Schmitz A, Nyegaard M, Johnsen HE, Bøgsted M.

BMC Cancer. 2015 Apr 8;15:235. doi: 10.1186/s12885-015-1237-6.

48.

Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis.

Dybkær K, Bøgsted M, Falgreen S, Bødker JS, Kjeldsen MK, Schmitz A, Bilgrau AE, Xu-Monette ZY, Li L, Bergkvist KS, Laursen MB, Rodrigo-Domingo M, Marques SC, Rasmussen SB, Nyegaard M, Gaihede M, Møller MB, Samworth RJ, Shah RD, Johansen P, El-Galaly TC, Young KH, Johnsen HE.

J Clin Oncol. 2015 Apr 20;33(12):1379-88. doi: 10.1200/JCO.2014.57.7080. Epub 2015 Mar 23.

49.

A novel single nucleotide splice site mutation in FHL1 confirms an Emery-Dreifuss plus phenotype with pulmonary artery hypoplasia and facial dysmorphology.

Pen AE, Nyegaard M, Fang M, Jiang H, Christensen R, Mølgaard H, Andersen H, Ulhøi BP, Østergaard JR, Væth S, Sommerlund M, de Brouwer AP, Zhang X, Jensen UB.

Eur J Med Genet. 2015 Apr;58(4):222-9. doi: 10.1016/j.ejmg.2015.02.003. Epub 2015 Feb 25.

PMID:
25724586
50.

Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes.

Søndergaard MT, Sorensen AB, Skov LL, Kjaer-Sorensen K, Bauer MC, Nyegaard M, Linse S, Oxvig C, Overgaard MT.

FEBS J. 2015 Feb;282(4):803-16. doi: 10.1111/febs.13184. Epub 2015 Jan 14.

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