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Items: 1 to 50 of 133

1.

Histone Chaperone Nap1 Is a Major Regulator of Histone H2A-H2B Dynamics at the Inducible GAL Locus.

Chen X, D'Arcy S, Radebaugh CA, Krzizike DD, Giebler HA, Huang L, Nyborg JK, Luger K, Stargell LA.

Mol Cell Biol. 2016 Mar 31;36(8):1287-96. doi: 10.1128/MCB.00835-15. Print 2016 Apr.

2.

Eviction of linker histone H1 by NAP-family histone chaperones enhances activated transcription.

Zhang Q, Giebler HA, Isaacson MK, Nyborg JK.

Epigenetics Chromatin. 2015 Sep 4;8:30. doi: 10.1186/s13072-015-0022-8. eCollection 2015.

3.

Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.

Pujari R, Hunte R, Thomas R, van der Weyden L, Rauch D, Ratner L, Nyborg JK, Ramos JC, Takai Y, Shembade N.

PLoS Pathog. 2015 Mar 16;11(3):e1004721. doi: 10.1371/journal.ppat.1004721. eCollection 2015 Mar.

4.

Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism.

Blakeslee WW, Wysoczynski CL, Fritz KS, Nyborg JK, Churchill ME, McKinsey TA.

Cell Signal. 2014 Dec;26(12):2912-20. doi: 10.1016/j.cellsig.2014.09.005. Epub 2014 Sep 16.

5.

Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14.

Luebben WR, Sharma N, Nyborg JK.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19254-9. doi: 10.1073/pnas.1009650107. Epub 2010 Oct 25.

6.

Activator-dependent p300 acetylation of chromatin in vitro: enhancement of transcription by disruption of repressive nucleosome-nucleosome interactions.

Szerlong HJ, Prenni JE, Nyborg JK, Hansen JC.

J Biol Chem. 2010 Oct 15;285(42):31954-64. doi: 10.1074/jbc.M110.148718. Epub 2010 Aug 18.

7.

Histone chaperones, histone acetylation, and the fluidity of the chromogenome.

Hansen JC, Nyborg JK, Luger K, Stargell LA.

J Cell Physiol. 2010 Aug;224(2):289-99. doi: 10.1002/jcp.22150.

8.

The HTLV-1 tax protein cooperates with phosphorylated CREB, TORC2 and p300 to activate CRE-dependent cyclin D1 transcription.

Kim YM, Geiger TR, Egan DI, Sharma N, Nyborg JK.

Oncogene. 2010 Apr 8;29(14):2142-52. doi: 10.1038/onc.2009.498. Epub 2010 Jan 25.

9.

The HTLV-1 Tax protein: revealing mechanisms of transcriptional activation through histone acetylation and nucleosome disassembly.

Nyborg JK, Egan D, Sharma N.

Biochim Biophys Acta. 2010 Mar-Apr;1799(3-4):266-74. doi: 10.1016/j.bbagrm.2009.09.002. Epub 2009 Sep 25. Review.

PMID:
19782779
10.
11.

RGS13 acts as a nuclear repressor of CREB.

Xie Z, Geiger TR, Johnson EN, Nyborg JK, Druey KM.

Mol Cell. 2008 Sep 5;31(5):660-70. doi: 10.1016/j.molcel.2008.06.024.

12.

The coactivators CBP/p300 and the histone chaperone NAP1 promote transcription-independent nucleosome eviction at the HTLV-1 promoter.

Sharma N, Nyborg JK.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):7959-63. doi: 10.1073/pnas.0800534105. Epub 2008 Jun 3.

13.
14.

Molecular characterization of HTLV-1 Tax interaction with the KIX domain of CBP/p300.

Ramírez JA, Nyborg JK.

J Mol Biol. 2007 Sep 28;372(4):958-969. doi: 10.1016/j.jmb.2007.06.062. Epub 2007 Jun 29.

15.

Purification of CREB to apparent homogeneity: removal of truncation products and contaminating nucleic acid.

Lopez DI, Mick JE, Nyborg JK.

Protein Expr Purif. 2007 Oct;55(2):406-18. Epub 2007 Jul 31.

17.

Molecular characterization of the Tax-containing HTLV-1 enhancer complex reveals a prominent role for CREB phosphorylation in Tax transactivation.

Kim YM, Ramírez JA, Mick JE, Giebler HA, Yan JP, Nyborg JK.

J Biol Chem. 2007 Jun 29;282(26):18750-7. Epub 2007 Apr 20.

18.

Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription.

Lemasson I, Lewis MR, Polakowski N, Hivin P, Cavanagh MH, Thébault S, Barbeau B, Nyborg JK, Mesnard JM.

J Virol. 2007 Feb;81(4):1543-53. Epub 2006 Dec 6.

20.

Tax abolishes histone H1 repression of p300 acetyltransferase activity at the human T-cell leukemia virus type 1 promoter.

Konesky KL, Nyborg JK, Laybourn PJ.

J Virol. 2006 Nov;80(21):10542-53. Epub 2006 Aug 30.

21.

The structure of bovine complement component 3 reveals the basis for thioester function.

Fredslund F, Jenner L, Husted LB, Nyborg J, Andersen GR, Sottrup-Jensen L.

J Mol Biol. 2006 Aug 4;361(1):115-27. Epub 2006 Jun 21.

PMID:
16831446
22.

Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.

Parmeggiani A, Krab IM, Okamura S, Nielsen RC, Nyborg J, Nissen P.

Biochemistry. 2006 Jun 6;45(22):6846-57.

PMID:
16734421
23.

Tax-dependent displacement of nucleosomes during transcriptional activation of human T-cell leukemia virus type 1.

Lemasson I, Polakowski NJ, Laybourn PJ, Nyborg JK.

J Biol Chem. 2006 May 12;281(19):13075-82. Epub 2006 Mar 18.

24.

Enacyloxin IIa pinpoints a binding pocket of elongation factor Tu for development of novel antibiotics.

Parmeggiani A, Krab IM, Watanabe T, Nielsen RC, Dahlberg C, Nyborg J, Nissen P.

J Biol Chem. 2006 Feb 3;281(5):2893-900. Epub 2005 Oct 28.

25.

Dual-mode recognition of noncanonical tRNAs(Ser) by seryl-tRNA synthetase in mammalian mitochondria.

Chimnaronk S, Gravers Jeppesen M, Suzuki T, Nyborg J, Watanabe K.

EMBO J. 2005 Oct 5;24(19):3369-79. Epub 2005 Sep 15.

26.

Crystal structure of the bovine mitochondrial elongation factor Tu.Ts complex.

Jeppesen MG, Navratil T, Spremulli LL, Nyborg J.

J Biol Chem. 2005 Feb 11;280(6):5071-81. Epub 2004 Nov 22.

27.

Paradoxical effects of DNA binding polyamides on HTLV-1 transcription.

Livengood JA, Fechter EJ, Dervan PB, Nyborg JK.

Front Biosci. 2004 Sep 1;9:3058-67.

PMID:
15353337
28.
29.
30.

Crystallization and preliminary X-ray diffraction study of mammalian mitochondrial seryl-tRNA synthetase.

Chimnaronk S, Jeppesen MG, Shimada N, Suzuki T, Nyborg J, Watanabe K.

Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1319-22. Epub 2004 Jun 22.

PMID:
15213404
31.

The high-affinity Sp1 binding site in the HTLV-1 promoter contributes to Tax-independent basal expression.

Livengood JA, Nyborg JK.

Nucleic Acids Res. 2004 May 20;32(9):2829-37. Print 2004.

32.

The crystal structure of the glutathione S-transferase-like domain of elongation factor 1Bgamma from Saccharomyces cerevisiae.

Jeppesen MG, Ortiz P, Shepard W, Kinzy TG, Nyborg J, Andersen GR.

J Biol Chem. 2003 Nov 21;278(47):47190-8. Epub 2003 Sep 12.

33.

Elongation factors in protein biosynthesis.

Andersen GR, Nissen P, Nyborg J.

Trends Biochem Sci. 2003 Aug;28(8):434-41. Review.

PMID:
12932732
34.

Preferential binding of the histone (H3-H4)2 tetramer by NAP1 is mediated by the amino-terminal histone tails.

McBryant SJ, Park YJ, Abernathy SM, Laybourn PJ, Nyborg JK, Luger K.

J Biol Chem. 2003 Nov 7;278(45):44574-83. Epub 2003 Aug 19.

35.
36.

Structural studies of eukaryotic elongation factors.

Andersen GR, Nyborg J.

Cold Spring Harb Symp Quant Biol. 2001;66:425-37. Review. No abstract available.

PMID:
12762045
37.
38.
39.

Thermal stability of aminoacyl-tRNAs in aqueous solutions.

Stepanov VG, Nyborg J.

Extremophiles. 2002 Dec;6(6):485-90. Epub 2002 Sep 4.

PMID:
12486457
40.

Isolation, crystallisation, and preliminary X-ray analysis of the bovine mitochondrial EF-Tu:GDP and EF-Tu:EF-Ts complexes.

Karring H, Andersen GR, Thirup SS, Nyborg J, Spremulli LL, Clark BF.

Biochim Biophys Acta. 2002 Dec 16;1601(2):172-7.

PMID:
12445479
41.

Transcription factor binding and histone modifications on the integrated proviral promoter in human T-cell leukemia virus-I-infected T-cells.

Lemasson I, Polakowski NJ, Laybourn PJ, Nyborg JK.

J Biol Chem. 2002 Dec 20;277(51):49459-65. Epub 2002 Oct 16.

42.

p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300.

Livengood JA, Scoggin KE, Van Orden K, McBryant SJ, Edayathumangalam RS, Laybourn PJ, Nyborg JK.

J Biol Chem. 2002 Mar 15;277(11):9054-61. Epub 2002 Jan 8.

43.

Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1.

Vestergaard B, Van LB, Andersen GR, Nyborg J, Buckingham RH, Kjeldgaard M.

Mol Cell. 2001 Dec;8(6):1375-82.

44.

p300-mediated tax transactivation from recombinant chromatin: histone tail deletion mimics coactivator function.

Georges SA, Kraus WL, Luger K, Nyborg JK, Laybourn PJ.

Mol Cell Biol. 2002 Jan;22(1):127-37.

45.
46.

Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.

Andersen GR, Valente L, Pedersen L, Kinzy TG, Nyborg J.

Nat Struct Biol. 2001 Jun;8(6):531-4.

PMID:
11373622
47.
48.

Efficient separation of Thermus aquaticus EF-Tu functional complexes.

Stepanov VG, Nyborg J.

Biochem Biophys Res Commun. 2001 Mar 23;282(1):108-15.

PMID:
11263979
49.

An "elongated" translation elongation factor Tu for truncated tRNAs in nematode mitochondria.

Ohtsuki T, Watanabe Yi, Takemoto C, Kawai G, Ueda T, Kita K, Kojima S, Kaziro Y, Nyborg J, Watanabe K.

J Biol Chem. 2001 Jun 15;276(24):21571-7. Epub 2001 Mar 21.

50.

Crystallization of the yeast elongation factor complex eEF1A-eEF1B alpha.

Pedersen L, Andersen GR, Knudsen CR, Kinzy TG, Nyborg J.

Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):159-61.

PMID:
11134944

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