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Items: 1 to 50 of 378

1.

Renal vascular resistance is increased in patients with kidney transplant.

Päivärinta J, Oikonen V, Räisänen-Sokolowski A, Tolvanen T, Löyttyniemi E, Iida H, Nuutila P, Metsärinne K, Koivuviita N.

BMC Nephrol. 2019 Nov 27;20(1):437. doi: 10.1186/s12882-019-1617-2.

2.

Renal hemodynamics and fatty acid uptake: effects of obesity and weight loss.

Rebelos E, Dadson P, Oikonen V, Iida H, Hannukainen JC, Iozzo P, Ferrannini E, Nuutila P.

Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E871-E878. doi: 10.1152/ajpendo.00135.2019. Epub 2019 Sep 24.

PMID:
31550182
3.

The Clinical Impact of Using 18F-FDG-PET/CT in the Diagnosis of Suspected Vasculitis: The Effect of Dose and Timing of Glucocorticoid Treatment.

Taimen K, Salomäki SP, Hohenthal U, Mali M, Kajander S, Seppänen M, Nuutila P, Palomäki A, Roivainen A, Pirilä L, Kemppainen J.

Contrast Media Mol Imaging. 2019 Aug 29;2019:9157637. doi: 10.1155/2019/9157637. eCollection 2019.

4.

Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia.

Motiani KK, Collado MC, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Salminen S, Nuutila P, Kalliokoski KK, Hannukainen JC.

Med Sci Sports Exerc. 2020 Jan;52(1):94-104. doi: 10.1249/MSS.0000000000002112.

PMID:
31425383
5.

Exercise training alters lipoprotein particles independent of brown adipose tissue metabolic activity.

Motiani P, Teuho J, Saari T, Virtanen KA, Honkala SM, Middelbeek RJ, Goodyear LJ, Eskola O, Andersson J, Löyttyniemi E, Hannukainen JC, Nuutila P.

Obes Sci Pract. 2019 Apr 24;5(3):258-272. doi: 10.1002/osp4.330. eCollection 2019 Jun.

6.

TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism.

Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Pasquale Nigro, Ryan RE, Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM, Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S, Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ.

Nat Metab. 2019 Feb;1(2):291-303. doi: 10.1038/s42255-018-0030-7. Epub 2019 Feb 11.

7.

Effects of short-term sprint interval and moderate-intensity continuous training on liver fat content, lipoprotein profile, and substrate uptake: a randomized trial.

Motiani KK, Savolainen AM, Toivanen J, Eskelinen JJ, Yli-Karjanmaa M, Virtanen KA, Saunavaara V, Heiskanen MA, Parkkola R, Haaparanta-Solin M, Solin O, Savisto N, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC.

J Appl Physiol (1985). 2019 Jun 1;126(6):1756-1768. doi: 10.1152/japplphysiol.00900.2018. Epub 2019 Apr 18.

PMID:
30998125
8.

The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients.

Latva-Rasku A, Honka MJ, Kullberg J, Mononen N, Lehtimäki T, Saltevo J, Kirjavainen AK, Saunavaara V, Iozzo P, Johansson L, Oscarsson J, Hannukainen JC, Nuutila P.

Diabetes Care. 2019 May;42(5):931-937. doi: 10.2337/dc18-1569. Epub 2019 Mar 18.

PMID:
30885955
9.

Effects of DAPAgliflozin on CARDiac substrate uptake, myocardial efficiency, and myocardial contractile work in type 2 diabetes patients-a description of the DAPACARD study.

Åkerblom A, Oldgren J, Latva-Rasku A, Johansson L, Lisovskaja V, Karlsson C, Oscarsson J, Nuutila P.

Ups J Med Sci. 2019 Jan;124(1):59-64. doi: 10.1080/03009734.2018.1515281. Epub 2019 Jan 8.

10.

Glucagon-like peptide-1 receptor expression after myocardial infarction: Imaging study using 68Ga-NODAGA-exendin-4 positron emission tomography.

Ståhle M, Kytö V, Kiugel M, Liljenbäck H, Metsälä O, Käkelä M, Li XG, Oikonen V, Saukko P, Nuutila P, Knuuti J, Roivainen A, Saraste A.

J Nucl Cardiol. 2018 Dec 13. doi: 10.1007/s12350-018-01547-1. [Epub ahead of print]

PMID:
30547299
11.

Effects of bariatric surgery on retinal microvascular architecture in obese patients.

Viljanen A, Soinio M, Cheung CY, Hannukainen JC, Karlsson HK, Wong TY, Hughes AD, Salminen P, Nuutila P, Vesti E, Tapp RJ.

Int J Obes (Lond). 2019 Sep;43(9):1675-1680. doi: 10.1038/s41366-018-0242-7. Epub 2018 Dec 5.

PMID:
30518825
12.

Opioidergic Regulation of Emotional Arousal: A Combined PET-fMRI Study.

Karjalainen T, Seppälä K, Glerean E, Karlsson HK, Lahnakoski JM, Nuutila P, Jääskeläinen IP, Hari R, Sams M, Nummenmaa L.

Cereb Cortex. 2019 Aug 14;29(9):4006-4016. doi: 10.1093/cercor/bhy281.

PMID:
30475982
13.

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation.

Li Y, Schnabl K, Gabler SM, Willershäuser M, Reber J, Karlas A, Laurila S, Lahesmaa M, U Din M, Bast-Habersbrunner A, Virtanen KA, Fromme T, Bolze F, O'Farrell LS, Alsina-Fernandez J, Coskun T, Ntziachristos V, Nuutila P, Klingenspor M.

Cell. 2018 Nov 29;175(6):1561-1574.e12. doi: 10.1016/j.cell.2018.10.016. Epub 2018 Nov 15.

14.

Characteristics and Outcomes of 79 Patients with an Insulinoma: A Nationwide Retrospective Study in Finland.

Peltola E, Hannula P, Huhtala H, Metso S, Kiviniemi U, Vornanen M, Sand J, Laukkarinen J, Tiikkainen M, Schalin-Jäntti C, Arola J, Sirén J, Piiroinen A, Soinio M, Nuutila P, Söderström M, Hämäläinen H, Moilanen L, Laaksonen D, Pirinen E, Sundelin F, Ebeling T, Salmela P, Mäkinen MJ, Jaatinen P.

Int J Endocrinol. 2018 Oct 23;2018:2059481. doi: 10.1155/2018/2059481. eCollection 2018.

15.

BATLAS: Deconvoluting Brown Adipose Tissue.

Perdikari A, Leparc GG, Balaz M, Pires ND, Lidell ME, Sun W, Fernandez-Albert F, Müller S, Akchiche N, Dong H, Balazova L, Opitz L, Röder E, Klein H, Stefanicka P, Varga L, Nuutila P, Virtanen KA, Niemi T, Taittonen M, Rudofsky G, Ukropec J, Enerbäck S, Stupka E, Neubauer H, Wolfrum C.

Cell Rep. 2018 Oct 16;25(3):784-797.e4. doi: 10.1016/j.celrep.2018.09.044.

16.

Fat Grafting Can Induce Browning of White Adipose Tissue.

Hoppela E, Grönroos TJ, Saarikko AM, Tervala TV, Kauhanen S, Nuutila P, Kivinen K, Hartiala P.

Plast Reconstr Surg Glob Open. 2018 Jun 19;6(6):e1804. doi: 10.1097/GOX.0000000000001804. eCollection 2018 Jun.

17.

Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery.

Savolainen AM, Karmi A, Immonen H, Soinio M, Saunavaara V, Pham T, Salminen P, Helmiö M, Ovaska J, Löyttyniemi E, Heiskanen MA, Lehtimäki T, Mari A, Nuutila P, Hannukainen JC.

Med Sci Sports Exerc. 2019 Feb;51(2):278-287. doi: 10.1249/MSS.0000000000001778.

18.

Adipose tissue and skeletal muscle insulin-mediated glucose uptake in insulin resistance: role of blood flow and diabetes.

Ferrannini E, Iozzo P, Virtanen KA, Honka MJ, Bucci M, Nuutila P.

Am J Clin Nutr. 2018 Oct 1;108(4):749-758. doi: 10.1093/ajcn/nqy162.

PMID:
30239554
19.

The effect of bariatric surgery on intraocular pressure.

Viljanen A, Hannukainen JC, Soinio M, Karlsson HK, Salminen P, Nuutila P, Vesti E.

Acta Ophthalmol. 2018 Dec;96(8):849-852. doi: 10.1111/aos.13826. Epub 2018 Sep 20.

20.

Correction to: Regulation of human brown adipose tissue by adenosine and A2A receptors - studies with [15O]H2O and [11C]TMSX PET/CT.

Lahesmaa M, Oikonen V, Helin S, Luoto P, U Din M, Pfeifer A, Nuutila P, Virtanen KA.

Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2244. doi: 10.1007/s00259-018-4144-7.

21.

Regulation of human brown adipose tissue by adenosine and A2A receptors - studies with [15O]H2O and [11C]TMSX PET/CT.

Lahesmaa M, Oikonen V, Helin S, Luoto P, U Din M, Pfeifer A, Nuutila P, Virtanen KA.

Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):743-750. doi: 10.1007/s00259-018-4120-2. Epub 2018 Aug 13. Erratum in: Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2244.

22.

Brain glucose uptake is associated with endogenous glucose production in obese patients before and after bariatric surgery and predicts metabolic outcome at follow-up.

Rebelos E, Immonen H, Bucci M, Hannukainen JC, Nummenmaa L, Honka MJ, Soinio M, Salminen P, Ferrannini E, Iozzo P, Nuutila P.

Diabetes Obes Metab. 2019 Feb;21(2):218-226. doi: 10.1111/dom.13501. Epub 2018 Sep 16.

23.

Liver blood dynamics after bariatric surgery: the effects of mixed-meal test and incretin infusions.

Honka H, Koffert J, Kauhanen S, Kudomi N, Hurme S, Mari A, Lindqvist A, Wierup N, Parkkola R, Groop L, Nuutila P.

Endocr Connect. 2018 Jul;7(7):888-896. doi: 10.1530/EC-18-0234. Epub 2018 Jun 25.

24.

Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis.

U Din M, Saari T, Raiko J, Kudomi N, Maurer SF, Lahesmaa M, Fromme T, Amri EZ, Klingenspor M, Solin O, Nuutila P, Virtanen KA.

Cell Metab. 2018 Aug 7;28(2):207-216.e3. doi: 10.1016/j.cmet.2018.05.020. Epub 2018 Jun 14.

25.

The renal blood flow reserve in healthy humans and patients with atherosclerotic renovascular disease measured by positron emission tomography using [15O]H2O.

Päivärinta J, Koivuviita N, Oikonen V, Iida H, Liukko K, Manner I, Löyttyniemi E, Nuutila P, Metsärinne K.

EJNMMI Res. 2018 Jun 11;8(1):45. doi: 10.1186/s13550-018-0395-3.

26.

Skin temperature may not yield human brown adipose tissue activity in diverse populations.

Sarasniemi JT, Koskensalo K, Raiko J, Nuutila P, Saunavaara J, Parkkola R, Virtanen KA.

Acta Physiol (Oxf). 2018 Nov;224(3):e13095. doi: 10.1111/apha.13095. Epub 2018 May 28. No abstract available.

PMID:
29757496
27.

Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial.

Heiskanen MA, Motiani KK, Mari A, Saunavaara V, Eskelinen JJ, Virtanen KA, Koivumäki M, Löyttyniemi E, Nuutila P, Kalliokoski KK, Hannukainen JC.

Diabetologia. 2018 Aug;61(8):1817-1828. doi: 10.1007/s00125-018-4627-x. Epub 2018 May 2.

28.

μ-opioid receptor system mediates reward processing in humans.

Nummenmaa L, Saanijoki T, Tuominen L, Hirvonen J, Tuulari JJ, Nuutila P, Kalliokoski K.

Nat Commun. 2018 Apr 16;9(1):1500. doi: 10.1038/s41467-018-03848-y.

29.

Binge eating disorder and morbid obesity are associated with lowered mu-opioid receptor availability in the brain.

Joutsa J, Karlsson HK, Majuri J, Nuutila P, Helin S, Kaasinen V, Nummenmaa L.

Psychiatry Res Neuroimaging. 2018 Jun 30;276:41-45. doi: 10.1016/j.pscychresns.2018.03.006. Epub 2018 Mar 9.

PMID:
29655552
30.

Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue.

Lahesmaa M, Eriksson O, Gnad T, Oikonen V, Bucci M, Hirvonen J, Koskensalo K, Teuho J, Niemi T, Taittonen M, Lahdenpohja S, U Din M, Haaparanta-Solin M, Pfeifer A, Virtanen KA, Nuutila P.

Diabetes. 2018 Jul;67(7):1226-1236. doi: 10.2337/db17-1366. Epub 2018 Apr 12.

31.

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study.

Honka MJ, Latva-Rasku A, Bucci M, Virtanen KA, Hannukainen JC, Kalliokoski KK, Nuutila P.

Eur J Endocrinol. 2018 May;178(5):523-531. doi: 10.1530/EJE-17-0882. Epub 2018 Mar 13.

32.

Brown adipose tissue lipid metabolism in morbid obesity: Effect of bariatric surgery-induced weight loss.

Dadson P, Hannukainen JC, Din MU, Lahesmaa M, Kalliokoski KK, Iozzo P, Pihlajamäki J, Karlsson HK, Parkkola R, Salminen P, Virtanen KA, Nuutila P.

Diabetes Obes Metab. 2018 May;20(5):1280-1288. doi: 10.1111/dom.13233. Epub 2018 Feb 22.

PMID:
29377423
33.

Morbid obesity and type 2 diabetes alter intestinal fatty acid uptake and blood flow.

Koffert J, Ståhle M, Karlsson H, Iozzo P, Salminen P, Roivainen A, Nuutila P.

Diabetes Obes Metab. 2018 Jun;20(6):1384-1390. doi: 10.1111/dom.13228. Epub 2018 Feb 11.

34.

Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase.

Lasar D, Rosenwald M, Kiehlmann E, Balaz M, Tall B, Opitz L, Lidell ME, Zamboni N, Krznar P, Sun W, Varga L, Stefanicka P, Ukropec J, Nuutila P, Virtanen K, Amri EZ, Enerbäck S, Wahli W, Wolfrum C.

Cell Rep. 2018 Jan 16;22(3):760-773. doi: 10.1016/j.celrep.2017.12.067.

35.

Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial.

Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P, Hurme S, Soinio M, Nuutila P, Victorzon M.

JAMA. 2018 Jan 16;319(3):241-254. doi: 10.1001/jama.2017.20313.

36.

Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery.

Hannukainen JC, Lautamäki R, Pärkkä J, Strandberg M, Saunavaara V, Hurme S, Soinio M, Dadson P, Virtanen KA, Grönroos T, Forsback S, Salminen P, Iozzo P, Nuutila P.

Diabetes Obes Metab. 2018 Apr;20(4):963-973. doi: 10.1111/dom.13183. Epub 2018 Jan 17.

37.

Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery.

Immonen H, Hannukainen JC, Kudomi N, Pihlajamäki J, Saunavaara V, Laine J, Salminen P, Lehtimäki T, Pham T, Iozzo P, Nuutila P.

Diabetes Care. 2018 Feb;41(2):368-371. doi: 10.2337/dc17-0738. Epub 2017 Nov 20.

PMID:
29158250
38.

A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study.

Latva-Rasku A, Honka MJ, Stančáková A, Koistinen HA, Kuusisto J, Guan L, Manning AK, Stringham H, Gloyn AL, Lindgren CM; T2D-GENES Consortium, Collins FS, Mohlke KL, Scott LJ, Karjalainen T, Nummenmaa L, Boehnke M, Nuutila P, Laakso M.

Diabetes. 2018 Feb;67(2):334-342. doi: 10.2337/db17-1142. Epub 2017 Nov 15.

39.

Head-to-Head Comparison of 68Ga-Citrate and 18F-FDG PET/CT for Detection of Infectious Foci in Patients with Staphylococcus aureus Bacteraemia.

Salomäki SP, Kemppainen J, Hohenthal U, Luoto P, Eskola O, Nuutila P, Seppänen M, Pirilä L, Oksi J, Roivainen A.

Contrast Media Mol Imaging. 2017 Oct 17;2017:3179607. doi: 10.1155/2017/3179607. eCollection 2017.

40.

Short-term interval training alters brain glucose metabolism in subjects with insulin resistance.

Honkala SM, Johansson J, Motiani KK, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC.

J Cereb Blood Flow Metab. 2018 Oct;38(10):1828-1838. doi: 10.1177/0271678X17734998. Epub 2017 Sep 29. Erratum in: J Cereb Blood Flow Metab. 2018 Jan 1;:271678X18766840.

41.

Dynamic changes in p66Shc mRNA expression in peripheral blood mononuclear cells following resistance training intervention in old frail women born to obese mothers: a pilot study.

Berry A, Bucci M, Raggi C, Eriksson JG, Guzzardi MA, Nuutila P, Huovinen V, Iozzo P, Cirulli F.

Aging Clin Exp Res. 2018 Jul;30(7):871-876. doi: 10.1007/s40520-017-0834-4. Epub 2017 Sep 26.

PMID:
28952131
42.

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial.

Koffert JP, Mikkola K, Virtanen KA, Andersson AD, Faxius L, Hällsten K, Heglind M, Guiducci L, Pham T, Silvola JMU, Virta J, Eriksson O, Kauhanen SP, Saraste A, Enerbäck S, Iozzo P, Parkkola R, Gomez MF, Nuutila P.

Diabetes Res Clin Pract. 2017 Sep;131:208-216. doi: 10.1016/j.diabres.2017.07.015. Epub 2017 Jul 20.

43.

Erratum. Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese. Diabetes 2013;62:2747-2751.

Tuulari JJ, Karlsson HK, Hirvonen J, Hannukainen JC, Bucci M, Helmiö M, Ovaska J, Soinio M, Salminen P, Savisto N, Nummenmaa L, Nuutila P.

Diabetes. 2017 Oct;66(10):2724. doi: 10.2337/db17-er10a. Epub 2017 Aug 1. No abstract available.

44.

Feeding Releases Endogenous Opioids in Humans.

Tuulari JJ, Tuominen L, de Boer FE, Hirvonen J, Helin S, Nuutila P, Nummenmaa L.

J Neurosci. 2017 Aug 23;37(34):8284-8291. doi: 10.1523/JNEUROSCI.0976-17.2017. Epub 2017 Jul 26.

45.

Dissociable Roles of Cerebral μ-Opioid and Type 2 Dopamine Receptors in Vicarious Pain: A Combined PET-fMRI Study.

Karjalainen T, Karlsson HK, Lahnakoski JM, Glerean E, Nuutila P, Jääskeläinen IP, Hari R, Sams M, Nummenmaa L.

Cereb Cortex. 2017 Aug 1;27(8):4257-4266. doi: 10.1093/cercor/bhx129.

PMID:
28541428
46.

Effects of atorvastatin and diet interventions on atherosclerotic plaque inflammation and [18F]FDG uptake in Ldlr-/-Apob100/100 mice.

Hellberg S, Sippola S, Liljenbäck H, Virta J, Silvola JMU, Ståhle M, Savisto N, Metso J, Jauhiainen M, Saukko P, Ylä-Herttuala S, Nuutila P, Knuuti J, Roivainen A, Saraste A.

Atherosclerosis. 2017 Aug;263:369-376. doi: 10.1016/j.atherosclerosis.2017.04.004. Epub 2017 Apr 11.

PMID:
28457625
47.

MR signal-fat-fraction analysis and T2* weighted imaging measure BAT reliably on humans without cold exposure.

Holstila M, Pesola M, Saari T, Koskensalo K, Raiko J, Borra RJ, Nuutila P, Parkkola R, Virtanen KA.

Metabolism. 2017 May;70:23-30. doi: 10.1016/j.metabol.2017.02.001. Epub 2017 Feb 8.

PMID:
28403942
48.

Fatty acid uptake and blood flow in adipose tissue compartments of morbidly obese subjects with or without type 2 diabetes: effects of bariatric surgery.

Dadson P, Ferrannini E, Landini L, Hannukainen JC, Kalliokoski KK, Vaittinen M, Honka H, Karlsson HK, Tuulari JJ, Soinio M, Salminen P, Parkkola R, Pihlajamäki J, Iozzo P, Nuutila P.

Am J Physiol Endocrinol Metab. 2017 Aug 1;313(2):E175-E182. doi: 10.1152/ajpendo.00044.2017. Epub 2017 Apr 11.

49.

Human Brown Fat Radiodensity Indicates Underlying Tissue Composition and Systemic Metabolic Health.

U Din M, Raiko J, Saari T, Saunavaara V, Kudomi N, Solin O, Parkkola R, Nuutila P, Virtanen KA.

J Clin Endocrinol Metab. 2017 Jul 1;102(7):2258-2267. doi: 10.1210/jc.2016-2698.

PMID:
28368474
50.

Human Brown Adipose Tissue Temperature and Fat Fraction Are Related to Its Metabolic Activity.

Koskensalo K, Raiko J, Saari T, Saunavaara V, Eskola O, Nuutila P, Saunavaara J, Parkkola R, Virtanen KA.

J Clin Endocrinol Metab. 2017 Apr 1;102(4):1200-1207. doi: 10.1210/jc.2016-3086.

PMID:
28323929

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