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Items: 1 to 50 of 197

1.

Intensity modulated radiotherapy in locally advanced thyroid cancer: Outcomes of a sequential phase I dose-escalation study.

Rooney KP, Miah AB, Bhide SA, Guerrero-Urbano MT, Sharabiani MT, Newbold KL, Grove L, Harrington KJ, Nutting CM.

Radiother Oncol. 2018 Apr;127(1):43-48. doi: 10.1016/j.radonc.2018.02.002. Epub 2018 Mar 7.

PMID:
29525412
2.

MRI-based Assessment of 3D Intrafractional Motion of Head and Neck Cancer for Radiation Therapy.

Gurney-Champion OJ, McQuaid D, Dunlop A, Wong KH, Welsh LC, Riddell AM, Koh DM, Oelfke U, Leach MO, Nutting CM, Bhide SA, Harrington KJ, Panek R, Newbold KL.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):306-316. doi: 10.1016/j.ijrobp.2017.10.016. Epub 2017 Oct 16.

3.

Changes in multimodality functional imaging parameters early during chemoradiation predict treatment response in patients with locally advanced head and neck cancer.

Wong KH, Panek R, Dunlop A, Mcquaid D, Riddell A, Welsh LC, Murray I, Koh DM, Leach MO, Bhide SA, Nutting CM, Oyen WJ, Harrington KJ, Newbold KL.

Eur J Nucl Med Mol Imaging. 2018 May;45(5):759-767. doi: 10.1007/s00259-017-3890-2. Epub 2017 Nov 21.

4.

The effect of parotid gland-sparing intensity-modulated radiotherapy on salivary composition, flow rate and xerostomia measures.

Richards TM, Hurley T, Grove L, Harrington KJ, Carpenter GH, Proctor GB, Nutting CM.

Oral Dis. 2017 Oct;23(7):990-1000. doi: 10.1111/odi.12686. Epub 2017 Jun 5.

PMID:
28434191
5.

Noninvasive Imaging of Cycling Hypoxia in Head and Neck Cancer Using Intrinsic Susceptibility MRI.

Panek R, Welsh L, Baker LCJ, Schmidt MA, Wong KH, Riddell AM, Koh DM, Dunlop A, Mcquaid D, d'Arcy JA, Bhide SA, Harrington KJ, Nutting CM, Hopkinson G, Richardson C, Box C, Eccles SA, Leach MO, Robinson SP, Newbold KL.

Clin Cancer Res. 2017 Aug 1;23(15):4233-4241. doi: 10.1158/1078-0432.CCR-16-1209. Epub 2017 Mar 17.

6.

The emerging potential of magnetic resonance imaging in personalizing radiotherapy for head and neck cancer: an oncologist's perspective.

Wong KH, Panek R, Bhide SA, Nutting CM, Harrington KJ, Newbold KL.

Br J Radiol. 2017 Mar;90(1071):20160768. doi: 10.1259/bjr.20160768. Review.

7.

HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation.

McLaughlin M, Barker HE, Khan AA, Pedersen M, Dillon M, Mansfield DC, Patel R, Kyula JN, Bhide SA, Newbold KL, Nutting CM, Harrington KJ.

BMC Cancer. 2017 Jan 31;17(1):86. doi: 10.1186/s12885-017-3084-0.

8.

Radiosensitization by the ATR Inhibitor AZD6738 through Generation of Acentric Micronuclei.

Dillon MT, Barker HE, Pedersen M, Hafsi H, Bhide SA, Newbold KL, Nutting CM, McLaughlin M, Harrington KJ.

Mol Cancer Ther. 2017 Jan;16(1):25-34. doi: 10.1158/1535-7163.MCT-16-0239. Epub 2016 Nov 9.

9.

Normal Tissue Complication Probability (NTCP) Modelling of Severe Acute Mucositis using a Novel Oral Mucosal Surface Organ at Risk.

Dean JA, Welsh LC, Wong KH, Aleksic A, Dunne E, Islam MR, Patel A, Patel P, Petkar I, Phillips I, Sham J, Schick U, Newbold KL, Bhide SA, Harrington KJ, Nutting CM, Gulliford SL.

Clin Oncol (R Coll Radiol). 2017 Apr;29(4):263-273. doi: 10.1016/j.clon.2016.12.001. Epub 2017 Jan 3.

10.

Metastatic Papillary Thyroid Carcinoma With Adjacent BRAF (V600E)-Mutated Squamous Cell Carcinoma.

Rupani A, Hughes OR, Watkinson J, Nutting CM, Thway K.

Int J Surg Pathol. 2017 May;25(3):243-245. doi: 10.1177/1066896916674811. Epub 2016 Oct 21. No abstract available.

PMID:
27829211
11.

Standardisation of Target Volume Delineation for Carotid-sparing Intensity-modulated Radiotherapy in Early Glottis Cancer.

Gujral DM, Long M, Roe JW, Harrington KJ, Nutting CM.

Clin Oncol (R Coll Radiol). 2017 Jan;29(1):42-50. doi: 10.1016/j.clon.2016.09.017. Epub 2016 Nov 1. Review.

PMID:
27815039
12.

HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology.

Schache AG, Powell NG, Cuschieri KS, Robinson M, Leary S, Mehanna H, Rapozo D, Long A, Cubie H, Junor E, Monaghan H, Harrington KJ, Nutting CM, Schick U, Lau AS, Upile N, Sheard J, Brougham K, West CM, Oguejiofor K, Thomas S, Ness AR, Pring M, Thomas GJ, King EV, McCance DJ, James JA, Moran M, Sloan P, Shaw RJ, Evans M, Jones TM.

Cancer Res. 2016 Nov 15;76(22):6598-6606. doi: 10.1158/0008-5472.CAN-16-0633. Epub 2016 Aug 28.

13.

Time-resolved angiography with stochastic trajectories for dynamic contrast-enhanced MRI in head and neck cancer: Are pharmacokinetic parameters affected?

Panek R, Schmidt MA, Borri M, Koh DM, Riddell A, Welsh L, Dunlop A, Powell C, Bhide SA, Nutting CM, Harrington KJ, Newbold KL, Leach MO.

Med Phys. 2016 Nov;43(11):6024.

PMID:
27806585
14.

Functional Data Analysis Applied to Modeling of Severe Acute Mucositis and Dysphagia Resulting From Head and Neck Radiation Therapy.

Dean JA, Wong KH, Gay H, Welsh LC, Jones AB, Schick U, Oh JH, Apte A, Newbold KL, Bhide SA, Harrington KJ, Deasy JO, Nutting CM, Gulliford SL.

Int J Radiat Oncol Biol Phys. 2016 Nov 15;96(4):820-831. doi: 10.1016/j.ijrobp.2016.08.013. Epub 2016 Aug 22.

15.

DARS: a phase III randomised multicentre study of dysphagia- optimised intensity- modulated radiotherapy (Do-IMRT) versus standard intensity- modulated radiotherapy (S-IMRT) in head and neck cancer.

Petkar I, Rooney K, Roe JW, Patterson JM, Bernstein D, Tyler JM, Emson MA, Morden JP, Mertens K, Miles E, Beasley M, Roques T, Bhide SA, Newbold KL, Harrington KJ, Hall E, Nutting CM.

BMC Cancer. 2016 Oct 6;16(1):770.

16.

Delayed DNA double-strand break repair following platin-based chemotherapy predicts treatment response in head and neck squamous cell carcinoma.

Bhide SA, Thway K, Lee J, Wong K, Clarke P, Newbold KL, Nutting CM, Harrington KJ.

Br J Cancer. 2016 Sep 27;115(7):825-30. doi: 10.1038/bjc.2016.266. Epub 2016 Sep 1.

17.

CHK1 Inhibition Radiosensitizes Head and Neck Cancers to Paclitaxel-Based Chemoradiotherapy.

Barker HE, Patel R, McLaughlin M, Schick U, Zaidi S, Nutting CM, Newbold KL, Bhide S, Harrington KJ.

Mol Cancer Ther. 2016 Sep;15(9):2042-54. doi: 10.1158/1535-7163.MCT-15-0998. Epub 2016 Jul 15.

18.

A randomised controlled trial of Caphosol mouthwash in management of radiation-induced mucositis in head and neck cancer.

Wong KH, Kuciejewska A, Sharabiani MTA, Ng-Cheng-Hin B, Hoy S, Hurley T, Rydon J, Grove L, Santos A, Ryugenji M, Bhide SA, Nutting CM, Harrington KJ, Newbold KL.

Radiother Oncol. 2017 Feb;122(2):207-211. doi: 10.1016/j.radonc.2016.06.015. Epub 2016 Jul 5.

PMID:
27393218
19.

Contrast enhancement of carotid adventitial vasa vasorum as a biomarker of radiation-induced atherosclerosis.

Gujral DM, Cheung WK, Shah BN, Chahal NS, Bhattacharyya S, Hooper J, Senior R, Tang MX, Harrington KJ, Nutting CM.

Radiother Oncol. 2016 Jul;120(1):63-8. doi: 10.1016/j.radonc.2016.06.007. Epub 2016 Jun 29.

PMID:
27370203
20.

Evaluation of radiotherapy techniques for radical treatment of lateralised oropharyngeal cancers : Dosimetry and NTCP.

McQuaid D, Dunlop A, Nill S, Franzese C, Nutting CM, Harrington KJ, Newbold KL, Bhide SA.

Strahlenther Onkol. 2016 Aug;192(8):516-25. doi: 10.1007/s00066-016-0980-1. Epub 2016 Jun 13.

PMID:
27295511
21.

Normal tissue complication probability (NTCP) modelling using spatial dose metrics and machine learning methods for severe acute oral mucositis resulting from head and neck radiotherapy.

Dean JA, Wong KH, Welsh LC, Jones AB, Schick U, Newbold KL, Bhide SA, Harrington KJ, Nutting CM, Gulliford SL.

Radiother Oncol. 2016 Jul;120(1):21-7. doi: 10.1016/j.radonc.2016.05.015. Epub 2016 May 27.

22.

Plaque Neovascularization Is Increased in Human Carotid Atherosclerosis Related to Prior Neck Radiotherapy: A Contrast-Enhanced Ultrasound Study.

Shah BN, Gujral DM, Chahal NS, Harrington KJ, Nutting CM, Senior R.

JACC Cardiovasc Imaging. 2016 Jun;9(6):668-75. doi: 10.1016/j.jcmg.2015.07.026. Epub 2016 May 18.

23.

Total Mucosal Irradiation with Intensity-modulated Radiotherapy in Patients with Head and Neck Carcinoma of Unknown Primary: A Pooled Analysis of Two Prospective Studies.

Richards TM, Bhide SA, Miah AB, Del Rosario L, Bodla S, Thway K, Gujral DM, Rooney KP, Schick U, McGovern T, Grove L, Newbold KL, Harrington KJ, Nutting CM.

Clin Oncol (R Coll Radiol). 2016 Sep;28(9):e77-84. doi: 10.1016/j.clon.2016.04.035. Epub 2016 May 11.

24.

Recovery of Salivary Function: Contralateral Parotid-sparing Intensity-modulated Radiotherapy versus Bilateral Superficial Lobe Parotid-sparing Intensity-modulated Radiotherapy.

Miah AB, Gulliford SL, Morden J, Newbold KL, Bhide SA, Zaidi SH, Hall E, Harrington KJ, Nutting CM.

Clin Oncol (R Coll Radiol). 2016 Sep;28(9):e69-76. doi: 10.1016/j.clon.2016.02.009. Epub 2016 Mar 17.

25.

Assessment of fully-automated atlas-based segmentation of novel oral mucosal surface organ-at-risk.

Dean JA, Welsh LC, McQuaid D, Wong KH, Aleksic A, Dunne E, Islam MR, Patel A, Patel P, Petkar I, Phillips I, Sham J, Newbold KL, Bhide SA, Harrington KJ, Gulliford SL, Nutting CM.

Radiother Oncol. 2016 Apr;119(1):166-71. doi: 10.1016/j.radonc.2016.02.022. Epub 2016 Mar 9.

26.

Induction Chemotherapy Followed by Chemo-intensity-modulated Radiotherapy for Locally Advanced Nasopharyngeal Cancer.

Miah AB, Bhide SA, Del Rosario L, Matthews J, Nicol R, Tanay MA, Gupta S, Zaidi SH, Newbold KL, Harrington KJ, Nutting CM.

Clin Oncol (R Coll Radiol). 2016 Aug;28(8):e61-7. doi: 10.1016/j.clon.2016.01.012. Epub 2016 Feb 11.

PMID:
26876458
27.

Repeatability and sensitivity of T2* measurements in patients with head and neck squamous cell carcinoma at 3T.

Panek R, Welsh L, Dunlop A, Wong KH, Riddell AM, Koh DM, Schmidt MA, Doran S, Mcquaid D, Hopkinson G, Richardson C, Nutting CM, Bhide SA, Harrington KJ, Robinson SP, Newbold KL, Leach MO.

J Magn Reson Imaging. 2016 Jul;44(1):72-80. doi: 10.1002/jmri.25134. Epub 2016 Jan 22.

28.

Carotid intima-medial thickness as a marker of radiation-induced carotid atherosclerosis.

Gujral DM, Shah BN, Chahal NS, Bhattacharyya S, Hooper J, Senior R, Harrington KJ, Nutting CM.

Radiother Oncol. 2016 Feb;118(2):323-9. doi: 10.1016/j.radonc.2015.11.025. Epub 2015 Dec 17.

PMID:
26705683
29.

Swallowing performance and tube feeding status in patients treated with parotid-sparing intensity-modulated radiotherapy for head and neck cancer.

Roe JW, Carding PN, Drinnan MJ, Harrington KJ, Nutting CM.

Head Neck. 2016 Apr;38 Suppl 1:E1436-44. doi: 10.1002/hed.24255. Epub 2015 Nov 13.

PMID:
26566740
30.

Characterizing Heterogeneity within Head and Neck Lesions Using Cluster Analysis of Multi-Parametric MRI Data.

Borri M, Schmidt MA, Powell C, Koh DM, Riddell AM, Partridge M, Bhide SA, Nutting CM, Harrington KJ, Newbold KL, Leach MO.

PLoS One. 2015 Sep 23;10(9):e0138545. doi: 10.1371/journal.pone.0138545. eCollection 2015.

31.

Contrast-enhanced ultrasound to assess plaque neovascularization in irradiated carotid arteries.

Gujral DM, Shah BN, Bhattacharyya S, Senior R, Harrington KJ, Nutting CM.

Int J Cardiol. 2016 Jan 1;202:3-4. doi: 10.1016/j.ijcard.2015.08.176. Epub 2015 Aug 28. No abstract available.

PMID:
26368025
32.

Do traditional risk stratification models for cerebrovascular events apply in irradiated head and neck cancer patients?

Gujral DM, Shah BN, Chahal NS, Bhattacharyya S, Senior R, Harrington KJ, Nutting CM.

QJM. 2016 Jun;109(6):383-9. doi: 10.1093/qjmed/hcv120. Epub 2015 Jun 24.

PMID:
26109594
33.

The Radiotherapy Clinical Trial Research Landscape in the UK Between 2004 and 2013: A Cross-sectional Analysis.

Evans CM, Burnet NG, Hall E, Huddart RA, Nutting CM, Coles CE.

Clin Oncol (R Coll Radiol). 2015 Sep;27(9):491-4. doi: 10.1016/j.clon.2015.05.005. Epub 2015 Jun 6. No abstract available.

PMID:
26051438
34.

Arterial Stiffness as a Biomarker of Radiation-Induced Carotid Atherosclerosis.

Gujral DM, Shah BN, Chahal NS, Bhattacharyya S, Senior R, Harrington KJ, Nutting CM.

Angiology. 2016 Mar;67(3):266-71. doi: 10.1177/0003319715589520. Epub 2015 Jun 4.

PMID:
26045515
35.

Attenuation Correction and Normalisation for Quantification of Contrast Enhancement in Ultrasound Images of Carotid Arteries.

Cheung WK, Gujral DM, Shah BN, Chahal NS, Bhattacharyya S, Cosgrove DO, Eckersley RJ, Harrington KJ, Senior R, Nutting CM, Tang MX.

Ultrasound Med Biol. 2015 Jul;41(7):1876-83. doi: 10.1016/j.ultrasmedbio.2015.02.010. Epub 2015 Apr 3.

36.

A novel method for delineation of oral mucosa for radiotherapy dose-response studies.

Dean JA, Welsh LC, Gulliford SL, Harrington KJ, Nutting CM.

Radiother Oncol. 2015 Apr;115(1):63-6. doi: 10.1016/j.radonc.2015.02.020. Epub 2015 Mar 13.

37.

Acoustic parameters of speech: Lack of correlation with perceptual and questionnaire-based speech evaluation in patients with oral and oropharyngeal cancer treated with primary surgery.

Dwivedi RC, St Rose S, Chisholm EJ, Clarke PM, Kerawala CJ, Nutting CM, Rhys-Evans PH, Kazi R, Harrington KJ.

Head Neck. 2016 May;38(5):670-6. doi: 10.1002/hed.23956. Epub 2015 Jun 25.

PMID:
25524696
38.

A phase II trial of induction chemotherapy and chemo-IMRT for head and neck squamous cell cancers at risk of bilateral nodal spread: the application of a bilateral superficial lobe parotid-sparing IMRT technique and treatment outcomes.

Miah AB, Schick U, Bhide SA, Guerrero-Urbano MT, Clark CH, Bidmead AM, Bodla S, Del Rosario L, Thway K, Wilson P, Newbold KL, Harrington KJ, Nutting CM.

Br J Cancer. 2015 Jan 6;112(1):32-8. doi: 10.1038/bjc.2014.553. Epub 2014 Dec 4.

39.

Patient-reported outcomes following parotid-sparing intensity-modulated radiotherapy for head and neck cancer. How important is dysphagia?

Roe JW, Drinnan MJ, Carding PN, Harrington KJ, Nutting CM.

Oral Oncol. 2014 Dec;50(12):1182-7. doi: 10.1016/j.oraloncology.2014.09.009. Epub 2014 Oct 14.

PMID:
25448227
40.

Final long-term results of a phase I/II study of dose-escalated intensity-modulated radiotherapy for locally advanced laryngo-hypopharyngeal cancers.

Gujral DM, Miah AB, Bodla S, Richards TM, Welsh L, Schick U, Powell CJ, Clark CH, Bidmead MA, Grove L, Guerrero-Urbano T, Bhide SA, Newbold KL, Harrington KJ, Nutting CM.

Oral Oncol. 2014 Nov;50(11):1089-97. doi: 10.1016/j.oraloncology.2014.07.018. Epub 2014 Sep 6.

PMID:
25200524
41.

Treatment-related dysgeusia in head and neck cancer patients.

Irune E, Dwivedi RC, Nutting CM, Harrington KJ.

Cancer Treat Rev. 2014 Oct;40(9):1106-17. doi: 10.1016/j.ctrv.2014.06.011. Epub 2014 Jul 5. Review.

PMID:
25064135
42.

Multiple cervical lymph node involvement and extra-capsular extension predict for contralateral nodal recurrence after ipsilateral radiotherapy for squamous cell carcinoma of the tonsil.

Lynch J, Lal P, Schick U, Nutting CM, Newbold K, Harrington K, Bhide S.

Oral Oncol. 2014 Sep;50(9):901-6. doi: 10.1016/j.oraloncology.2014.06.019. Epub 2014 Jul 19.

PMID:
25052236
43.

Neurocognitive function after (chemo)-radiotherapy for head and neck cancer.

Welsh LC, Dunlop AW, McGovern T, McQuaid D, Dean JA, Gulliford SL, Bhide SA, Harrington KJ, Nutting CM, Newbold KL.

Clin Oncol (R Coll Radiol). 2014 Dec;26(12):765-75. doi: 10.1016/j.clon.2014.06.014. Epub 2014 Jul 11. Review.

PMID:
25028338
44.

Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial.

Brose MS, Nutting CM, Jarzab B, Elisei R, Siena S, Bastholt L, de la Fouchardiere C, Pacini F, Paschke R, Shong YK, Sherman SI, Smit JW, Chung J, Kappeler C, Peña C, Molnár I, Schlumberger MJ; DECISION investigators.

Lancet. 2014 Jul 26;384(9940):319-28. doi: 10.1016/S0140-6736(14)60421-9. Epub 2014 Apr 24.

45.

Risk-adapted strategy partial liver irradiation for the treatment of large volume metastatic liver disease.

Aitken KL, Tait DM, Nutting CM, Khabra K, Hawkins MA.

Acta Oncol. 2014 May;53(5):702-6. doi: 10.3109/0284186X.2013.862595. Epub 2013 Dec 9. No abstract available.

PMID:
24313391
46.

Current attitudes of head and neck oncologists in the United Kingdom to induction chemotherapy for locally advanced head and neck cancer: a survey of centres participating in a national randomised controlled trial.

Gujral DM, Piercy D, Morden JP, Emson M, Hall E, Miah AB, Bhide SA, Newbold KL, Harrington KJ, Nutting CM.

Oral Oncol. 2014 Feb;50(2):141-6. doi: 10.1016/j.oraloncology.2013.10.012. Epub 2013 Nov 18.

PMID:
24263110
47.

Clinical features of radiation-induced carotid atherosclerosis.

Gujral DM, Shah BN, Chahal NS, Senior R, Harrington KJ, Nutting CM.

Clin Oncol (R Coll Radiol). 2014 Feb;26(2):94-102. doi: 10.1016/j.clon.2013.10.002. Epub 2013 Nov 1. Review.

PMID:
24188597
48.

Radiation-induced carotid artery atherosclerosis.

Gujral DM, Chahal N, Senior R, Harrington KJ, Nutting CM.

Radiother Oncol. 2014 Jan;110(1):31-8. doi: 10.1016/j.radonc.2013.08.009. Epub 2013 Sep 14. Review.

PMID:
24044796
49.

Fatigue during chemoradiotherapy for nasopharyngeal cancer and its relationship to radiation dose distribution in the brain.

Powell C, Schick U, Morden JP, Gulliford SL, Miah AB, Bhide S, Newbold K, Harrington KJ, Nutting CM.

Radiother Oncol. 2014 Mar;110(3):416-21. doi: 10.1016/j.radonc.2013.06.042. Epub 2013 Aug 13.

PMID:
23953411
50.

Dose-response analysis of parotid gland function: what is the best measure of xerostomia?

Miah AB, Gulliford SL, Clark CH, Bhide SA, Zaidi SH, Newbold KL, Harrington KJ, Nutting CM.

Radiother Oncol. 2013 Mar;106(3):341-5. doi: 10.1016/j.radonc.2013.03.009. Epub 2013 Apr 6.

PMID:
23566529

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