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A Two-Stage Tremor Detection Algorithm for Wearable Inertial Sensors During Normal Daily Activities.

McNames J, Shah VV, Mancini M, Curtze C, El-Gohary M, Aboy M, Carlson-Kuhta P, Nutt JG, Horak F.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:2535-2538. doi: 10.1109/EMBC.2019.8857133.


Quantity and quality of gait and turning in people with multiple sclerosis, Parkinson's disease and matched controls during daily living.

Shah VV, McNames J, Mancini M, Carlson-Kuhta P, Spain RI, Nutt JG, El-Gohary M, Curtze C, Horak FB.

J Neurol. 2020 Jan 11. doi: 10.1007/s00415-020-09696-5. [Epub ahead of print]


Effects of augmenting cholinergic neurotransmission on balance in Parkinson's disease.

Mancini M, Chung K, Zajack A, Martini DN, Ramsey K, Lapidus J, Horak FB, Nutt JG.

Parkinsonism Relat Disord. 2019 Dec;69:40-47. doi: 10.1016/j.parkreldis.2019.10.022. Epub 2019 Oct 23.


How to Select Balance Measures Sensitive to Parkinson's Disease from Body-Worn Inertial Sensors-Separating the Trees from the Forest.

Hasegawa N, Shah VV, Carlson-Kuhta P, Nutt JG, Horak FB, Mancini M.

Sensors (Basel). 2019 Jul 28;19(15). pii: E3320. doi: 10.3390/s19153320.


Non-Dopaminergic Therapies.

Nutt JG, Bohnen NI.

J Parkinsons Dis. 2018;8(s1):S73-S78. doi: 10.3233/JPD-181472. Review.


The Impact Of Freezing Of Gait On Balance Perception And Mobility In Community-Living With Parkinson'S Disease.

Mancini M, Curtze C, Stuart S, El-Gohary M, James, McNames, Nutt JG, Horak FB.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3040-3043. doi: 10.1109/EMBC.2018.8512910.


Assessment of an Objective Method of Dyskinesia Measurement in Parkinson's Disease.

Chung KA, Lobb BM, Murchison CF, Mancini M, Hogarth P, Nutt JG.

Mov Disord Clin Pract. 2018 Mar 2;5(2):160-164. doi: 10.1002/mdc3.12583. eCollection 2018 Mar-Apr.


Assessment of the ability of open- and closed-loop cueing to improve turning and freezing in people with Parkinson's disease.

Mancini M, Smulders K, Harker G, Stuart S, Nutt JG.

Sci Rep. 2018 Aug 24;8(1):12773. doi: 10.1038/s41598-018-31156-4.


Gait Stability Has Phase-Dependent Dual-Task Costs in Parkinson's Disease.

Fino PC, Mancini M, Curtze C, Nutt JG, Horak FB.

Front Neurol. 2018 May 30;9:373. doi: 10.3389/fneur.2018.00373. eCollection 2018.


Apraxia of gait- or apraxia of postural transitions?

Dale ML, Curtze C, Nutt JG.

Parkinsonism Relat Disord. 2018 May;50:19-22. doi: 10.1016/j.parkreldis.2018.02.024. Epub 2018 Feb 19. Review.


Neurological disorders of gait, balance and posture: a sign-based approach.

Nonnekes J, Goselink RJM, Růžička E, Fasano A, Nutt JG, Bloem BR.

Nat Rev Neurol. 2018 Mar;14(3):183-189. doi: 10.1038/nrneurol.2017.178. Epub 2018 Jan 29. Review.


Case Studies in Neuroscience: A dissociation of balance and posture demonstrated by camptocormia.

St George RJ, Gurfinkel VS, Kraakevik J, Nutt JG, Horak FB.

J Neurophysiol. 2018 Jan 1;119(1):33-38. doi: 10.1152/jn.00582.2017. Epub 2017 Oct 4.


Investigation of Anticipatory Postural Adjustments during One-Leg Stance Using Inertial Sensors: Evidence from Subjects with Parkinsonism.

Bonora G, Mancini M, Carpinella I, Chiari L, Ferrarin M, Nutt JG, Horak FB.

Front Neurol. 2017 Jul 25;8:361. doi: 10.3389/fneur.2017.00361. eCollection 2017.


Dual task interference on postural sway, postural transitions and gait in people with Parkinson's disease and freezing of gait.

de Souza Fortaleza AC, Mancini M, Carlson-Kuhta P, King LA, Nutt JG, Chagas EF, Freitas IF Junior, Horak FB.

Gait Posture. 2017 Jul;56:76-81. doi: 10.1016/j.gaitpost.2017.05.006. Epub 2017 May 10.


Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease.

Fox SH, Metman LV, Nutt JG, Brodsky M, Factor SA, Lang AE, Pope LE, Knowles N, Siffert J.

Mov Disord. 2017 Jun;32(6):893-903. doi: 10.1002/mds.26976. Epub 2017 Mar 30.


Impaired perception of surface tilt in progressive supranuclear palsy.

Dale ML, Horak FB, Wright WG, Schoneburg BM, Nutt JG, Mancini M.

PLoS One. 2017 Mar 7;12(3):e0173351. doi: 10.1371/journal.pone.0173351. eCollection 2017.


Recovery from Multiple APAs Delays Gait Initiation in Parkinson's Disease.

Cohen RG, Nutt JG, Horak FB.

Front Hum Neurosci. 2017 Feb 14;11:60. doi: 10.3389/fnhum.2017.00060. eCollection 2017.


The clinical significance of freezing while turning in Parkinson's disease.

Mancini M, Smulders K, Cohen RG, Horak FB, Giladi N, Nutt JG.

Neuroscience. 2017 Feb 20;343:222-228. doi: 10.1016/j.neuroscience.2016.11.045. Epub 2016 Dec 9.


Objective Gait and Balance Impairments Relate to Balance Confidence and Perceived Mobility in People With Parkinson Disease.

Curtze C, Nutt JG, Carlson-Kuhta P, Mancini M, Horak FB.

Phys Ther. 2016 Nov;96(11):1734-1743. Epub 2016 May 5.


Quantifying effects of age on balance and gait with inertial sensors in community-dwelling healthy adults.

Park JH, Mancini M, Carlson-Kuhta P, Nutt JG, Horak FB.

Exp Gerontol. 2016 Dec 1;85:48-58. doi: 10.1016/j.exger.2016.09.018. Epub 2016 Sep 22.


Pharmacological treatment in Parkinson's disease: Effects on gait.

Smulders K, Dale ML, Carlson-Kuhta P, Nutt JG, Horak FB.

Parkinsonism Relat Disord. 2016 Oct;31:3-13. doi: 10.1016/j.parkreldis.2016.07.006. Epub 2016 Jul 17. Review.


Motor subtype in Parkinson's disease: Different disorders or different stages of disease?

Nutt JG.

Mov Disord. 2016 Jul;31(7):957-61. doi: 10.1002/mds.26657. Epub 2016 May 26. Review. No abstract available.


Associations between mobility, cognition and callosal integrity in people with parkinsonism.

Fling BW, Dale ML, Curtze C, Smulders K, Nutt JG, Horak FB.

Neuroimage Clin. 2016 Mar 8;11:415-422. doi: 10.1016/j.nicl.2016.03.006. eCollection 2016.


Balance and Gait Represent Independent Domains of Mobility in Parkinson Disease.

Horak FB, Mancini M, Carlson-Kuhta P, Nutt JG, Salarian A.

Phys Ther. 2016 Sep;96(9):1364-71. doi: 10.2522/ptj.20150580. Epub 2016 Mar 31.


Effect of augmenting cholinergic function on gait and balance.

Mancini M, Fling BW, Gendreau A, Lapidus J, Horak FB, Chung K, Nutt JG.

BMC Neurol. 2015 Dec 23;15:264. doi: 10.1186/s12883-015-0523-x.


Do cognitive measures and brain circuitry predict outcomes of exercise in Parkinson Disease: a randomized clinical trial.

King LA, Peterson DS, Mancini M, Carlson-Kuhta P, Fling BW, Smulders K, Nutt JG, Dale M, Carter J, Winters-Stone KM, Horak FB.

BMC Neurol. 2015 Oct 24;15:218. doi: 10.1186/s12883-015-0474-2.


Continuous monitoring of turning in Parkinson's disease: Rehabilitation potential.

Mancini M, El-Gohary M, Pearson S, McNames J, Schlueter H, Nutt JG, King LA, Horak FB.

NeuroRehabilitation. 2015;37(1):3-10. doi: 10.3233/NRE-151236.


Levodopa Is a Double-Edged Sword for Balance and Gait in People With Parkinson's Disease.

Curtze C, Nutt JG, Carlson-Kuhta P, Mancini M, Horak FB.

Mov Disord. 2015 Sep;30(10):1361-70. doi: 10.1002/mds.26269. Epub 2015 Jun 12.


Freezing of gait: a practical approach to management.

Nonnekes J, Snijders AH, Nutt JG, Deuschl G, Giladi N, Bloem BR.

Lancet Neurol. 2015 Jul;14(7):768-78. doi: 10.1016/S1474-4422(15)00041-1. Epub 2015 May 24. Review.


Continuous levodopa infusion is better—for now.

Nutt JG.

Mov Disord. 2015 Apr;30(4):443-5. doi: 10.1002/mds.26169. Epub 2015 Mar 11. No abstract available.


Reply: Does dominant pedunculopontine nucleus exist? Probably not.

Fling BW, Nutt JG, Horak FB.

Brain. 2015 May;138(Pt 5):e347. doi: 10.1093/brain/awu317. Epub 2014 Nov 2. No abstract available.


Dual-task interference and brain structural connectivity in people with Parkinson's disease who freeze.

Peterson DS, Fling BW, Mancini M, Cohen RG, Nutt JG, Horak FB.

J Neurol Neurosurg Psychiatry. 2015 Jul;86(7):786-92. doi: 10.1136/jnnp-2014-308840. Epub 2014 Sep 15.


Reply: Does dominant pedunculopontine nucleus exist?

Fling BW, Nutt JG, Horak FB.

Brain. 2015 Feb;138(Pt 2):e324. doi: 10.1093/brain/awu226. Epub 2014 Aug 13. No abstract available.


Functional reorganization of the locomotor network in Parkinson patients with freezing of gait.

Fling BW, Cohen RG, Mancini M, Carpenter SD, Fair DA, Nutt JG, Horak FB.

PLoS One. 2014 Jun 17;9(6):e100291. doi: 10.1371/journal.pone.0100291. eCollection 2014.


Dual tasking during postural stepping responses increases falls but not freezing in people with Parkinson's disease.

Jacobs JV, Nutt JG, Carlson-Kuhta P, Allen R, Horak FB.

Parkinsonism Relat Disord. 2014 Jul;20(7):779-81. doi: 10.1016/j.parkreldis.2014.04.001. Epub 2014 Apr 14.


A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit.

Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, Griebner B, Watts A, Gao S, Pourcher E, Bond L, Kompoliti K, Agarwal P, Sia C, Jog M, Cole L, Sultana M, Kurlan R, Richard I, Deeley C, Waters CH, Figueroa A, Arkun A, Brodsky M, Ondo WG, Hunter CB, Jimenez-Shahed J, Palao A, Miyasaki JM, So J, Tetrud J, Reys L, Smith K, Singer C, Blenke A, Russell DS, Cotto C, Friedman JH, Lannon M, Zhang L, Drasby E, Kumar R, Subramanian T, Ford DS, Grimes DA, Cote D, Conway J, Siderowf AD, Evatt ML, Sommerfeld B, Lieberman AN, Okun MS, Rodriguez RL, Merritt S, Swartz CL, Martin WR, King P, Stover N, Guthrie S, Watts RL, Ahmed A, Fernandez HH, Winters A, Mari Z, Dawson TM, Dunlop B, Feigin AS, Shannon B, Nirenberg MJ, Ogg M, Ellias SA, Thomas CA, Frei K, Bodis-Wollner I, Glazman S, Mayer T, Hauser RA, Pahwa R, Langhammer A, Ranawaya R, Derwent L, Sethi KD, Farrow B, Prakash R, Litvan I, Robinson A, Sahay A, Gartner M, Hinson VK, Markind S, Pelikan M, Perlmutter JS, Hartlein J, Molho E, Evans S, Adler CH, Duffy A, Lind M, Elmer L, Davis K, Spears J, Wilson S, Leehey MA, Hermanowicz N, Niswonger S, Shill HA, Obradov S, Rajput A, Cowper M, Lessig S, Song D, Fontaine D, Zadikoff C, Williams K, Blindauer KA, Bergholte J, Propsom CS, Stacy MA, Field J, Mihaila D, Chilton M, Uc EY, Sieren J, Simon DK, Kraics L, Silver A, Boyd JT, Hamill RW, Ingvoldstad C, Young J, Thomas K, Kostyk SK, Wojcieszek J, Pfeiffer RF, Panisset M, Beland M, Reich SG, Cines M, Zappala N, Rivest J, Zweig R, Lumina LP, Hilliard CL, Grill S, Kellermann M, Tuite P, Rolandelli S, Kang UJ, Young J, Rao J, Cook MM, Severt L, Boyar K.

JAMA Neurol. 2014 May;71(5):543-52. doi: 10.1001/jamaneurol.2014.131.


The effect of deep brain stimulation randomized by site on balance in Parkinson's disease.

St George RJ, Carlson-Kuhta P, Nutt JG, Hogarth P, Burchiel KJ, Horak FB.

Mov Disord. 2014 Jun;29(7):949-53. doi: 10.1002/mds.25831. Epub 2014 Feb 14.


Inhibition, executive function, and freezing of gait.

Cohen RG, Klein KA, Nomura M, Fleming M, Mancini M, Giladi N, Nutt JG, Horak FB.

J Parkinsons Dis. 2014;4(1):111-22. doi: 10.3233/JPD-130221.


Cognitive and motor function in long-duration PARKIN-associated Parkinson disease.

Alcalay RN, Caccappolo E, Mejia-Santana H, Tang MX, Rosado L, Orbe Reilly M, Ruiz D, Louis ED, Comella CL, Nance MA, Bressman SB, Scott WK, Tanner CM, Mickel SF, Waters CH, Fahn S, Cote LJ, Frucht SJ, Ford B, Rezak M, Novak KE, Friedman JH, Pfeiffer RF, Marsh L, Hiner B, Payami H, Molho E, Factor SA, Nutt JG, Serrano C, Arroyo M, Ottman R, Pauciulo MW, Nichols WC, Clark LN, Marder KS.

JAMA Neurol. 2014 Jan;71(1):62-7. doi: 10.1001/jamaneurol.2013.4498.


Mobility, mood and site of care impact health related quality of life in Parkinson's disease.

Nutt JG, Siderowf AD, Guttman M, Schmidt PN, Zamudio JI, Wu SS, Okun MS, Simuni T, Parashos SA, Dahodwala NA, Davis TL, Giladi N, Gurevich T, Hauser RA, Jankovic J, Lyons KE, Marsh L, Miyasaki JM, Morgan JC, Santiago AJ, Tarsy D, Mari Z, Malaty IA, Nelson EC; National Parkinson Foundation Quality Improvement Initiative Investigators.

Parkinsonism Relat Disord. 2014 Mar;20(3):274-9. doi: 10.1016/j.parkreldis.2013.10.004. Epub 2013 Oct 16.


Performance of a motor task learned on levodopa deteriorates when subsequently practiced off.

Anderson ED, Horak FB, Lasarev MR, Nutt JG.

Mov Disord. 2014 Jan;29(1):54-60. doi: 10.1002/mds.25702. Epub 2013 Oct 16.


Higher-level gait disorders: an open frontier.

Nutt JG.

Mov Disord. 2013 Sep 15;28(11):1560-5. doi: 10.1002/mds.25673. Review.


Parkinsonism syndrome in heterozygotes for Niemann-Pick C1.

Kluenemann HH, Nutt JG, Davis MY, Bird TD.

J Neurol Sci. 2013 Dec 15;335(1-2):219-20. doi: 10.1016/j.jns.2013.08.033. Epub 2013 Sep 3.


Framework for understanding balance dysfunction in Parkinson's disease.

Schoneburg B, Mancini M, Horak F, Nutt JG.

Mov Disord. 2013 Sep 15;28(11):1474-82. doi: 10.1002/mds.25613. Epub 2013 Aug 7. Review.


Asymmetric pedunculopontine network connectivity in parkinsonian patients with freezing of gait.

Fling BW, Cohen RG, Mancini M, Nutt JG, Fair DA, Horak FB.

Brain. 2013 Aug;136(Pt 8):2405-18. doi: 10.1093/brain/awt172. Epub 2013 Jul 3.


Which dyskinesia scale best detects treatment response?

Goetz CG, Stebbins GT, Chung KA, Hauser RA, Miyasaki JM, Nicholas AP, Poewe W, Seppi K, Rascol O, Stacy MA, Nutt JG, Tanner CM, Urkowitz A, Jaglin JA, Ge S.

Mov Disord. 2013 Mar;28(3):341-6. doi: 10.1002/mds.25321. Epub 2013 Feb 6.


Quantifying freezing of gait in Parkinson's disease during the instrumented timed up and go test.

Mancini M, Priest KC, Nutt JG, Horak FB.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:1198-201. doi: 10.1109/EMBC.2012.6346151.


Authors' response to Marras and Oakes, 'Piecing together the puzzle of progression and mortality in Parkinson's disease'.

Holford NH, Vu TC, Nutt JG.

Br J Clin Pharmacol. 2013 May;75(5):1370-1. doi: 10.1111/j.1365-2125.2012.04465.x. No abstract available.


Postural sway as a marker of progression in Parkinson's disease: a pilot longitudinal study.

Mancini M, Carlson-Kuhta P, Zampieri C, Nutt JG, Chiari L, Horak FB.

Gait Posture. 2012 Jul;36(3):471-6. doi: 10.1016/j.gaitpost.2012.04.010. Epub 2012 Jun 29.


Are high doses of carbidopa a concern? A randomized, clinical trial in Parkinson's disease.

Brod LS, Aldred JL, Nutt JG.

Mov Disord. 2012 May;27(6):750-3. doi: 10.1002/mds.24998. Epub 2012 Apr 16.

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