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Managing the performance of general practitioners and specialists referral networks: A system for evaluating the heart failure pathway.

Nuti S, Ferré F, Seghieri C, Foresi E, Stukel TA.

Health Policy. 2019 Nov 14. pii: S0168-8510(19)30258-1. doi: 10.1016/j.healthpol.2019.11.001. [Epub ahead of print]


Formulation Design, Optimization and In Vivo Evaluations of an α-Tocopherol-Containing Self-Emulsified Adjuvant System using Inactivated Influenza Vaccine.

Lodaya RN, Kanitkar AP, Friedrich K, Henson D, Yamagata R, Nuti S, Mallett CP, Bertholet S, Amiji MM, O'Hagan DT.

J Control Release. 2019 Oct 31;316:12-21. doi: 10.1016/j.jconrel.2019.10.042. [Epub ahead of print]


Unraveling Structural Information of Turkevich Synthesized Plasmonic Gold-Silver Bimetallic Nanoparticles.

Blommaerts N, Vanrompay H, Nuti S, Lenaerts S, Bals S, Verbruggen SW.

Small. 2019 Oct;15(42):e1902791. doi: 10.1002/smll.201902791. Epub 2019 Aug 25.


Decision making tools for managing waiting times and treatment rates in elective surgery.

Lungu DA, Grillo Ruggieri T, Nuti S.

BMC Health Serv Res. 2019 Jun 11;19(1):369. doi: 10.1186/s12913-019-4199-6.


Health system performance assessment in small countries: The case study of Latvia.

Noto G, Corazza I, Kļaviņa K, Lepiksone J, Nuti S.

Int J Health Plann Manage. 2019 May 15. doi: 10.1002/hpm.2803. [Epub ahead of print]


Digoxin Use and Associated Adverse Events Among Older Adults.

Angraal S, Nuti SV, Masoudi FA, Freeman JV, Murugiah K, Shah ND, Desai NR, Ranasinghe I, Wang Y, Krumholz HM.

Am J Med. 2019 Oct;132(10):1191-1198. doi: 10.1016/j.amjmed.2019.04.022. Epub 2019 May 9.


Involving hybrid professionals in top management decision-making: How managerial training can make the difference.

Giacomelli G, Ferré F, Furlan M, Nuti S.

Health Serv Manage Res. 2019 Nov;32(4):168-179. doi: 10.1177/0951484819844778. Epub 2019 May 6. No abstract available.


Association of in-hospital resource utilization with post-acute spending in Medicare beneficiaries hospitalized for acute myocardial infarction: a cross-sectional study.

Nuti SV, Li SX, Xu X, Ott LS, Lagu T, Desai NR, Murugiah K, Duan M, Martin J, Kim N, Krumholz HM.

BMC Health Serv Res. 2019 Mar 25;19(1):190. doi: 10.1186/s12913-019-4018-0.


Geographic variation in inpatient costs for Acute Myocardial Infarction care: Insights from Italy.

Seghieri C, Berta P, Nuti S.

Health Policy. 2019 May;123(5):449-456. doi: 10.1016/j.healthpol.2019.01.010. Epub 2019 Mar 6.


Characterizing Subgroups of High-Need, High-Cost Patients Based on Their Clinical Conditions: a Machine Learning-Based Analysis of Medicaid Claims Data.

Nuti SV, Doupe P, Villanueva B, Scarpa J, Bruzelius E, Baum A.

J Gen Intern Med. 2019 Aug;34(8):1406-1408. doi: 10.1007/s11606-019-04941-8. No abstract available.


Variation in and Hospital Characteristics Associated With the Value of Care for Medicare Beneficiaries With Acute Myocardial Infarction, Heart Failure, and Pneumonia.

Desai NR, Ott LS, George EJ, Xu X, Kim N, Zhou S, Hsieh A, Nuti SV, Lin Z, Bernheim SM, Krumholz HM.

JAMA Netw Open. 2018 Oct 5;1(6):e183519. doi: 10.1001/jamanetworkopen.2018.3519.


Association of Racial and Socioeconomic Disparities With Outcomes Among Patients Hospitalized With Acute Myocardial Infarction, Heart Failure, and Pneumonia: An Analysis of Within- and Between-Hospital Variation.

Downing NS, Wang C, Gupta A, Wang Y, Nuti SV, Ross JS, Bernheim SM, Lin Z, Normand ST, Krumholz HM.

JAMA Netw Open. 2018 Sep 7;1(5):e182044. doi: 10.1001/jamanetworkopen.2018.2044.


Re-thinking performance assessment for primary care: Opinion of the expert panel on effective ways of investing in health.

Kringos D, Nuti S, Anastasy C, Barry M, Murauskiene L, Siciliani L, De Maeseneer J.

Eur J Gen Pract. 2019 Jan;25(1):55-61. doi: 10.1080/13814788.2018.1546284. Epub 2018 Dec 12.


Engineered Nanostructured Materials for Ofloxacin Delivery.

Nuti S, Fernández-Lodeiro J, Del Secco B, Rampazzo E, Rodríguez-González B, Capelo JL, Silva V, Igrejas G, Poeta P, Torres C, Zaccheroni N, Prodi L, Oliveira E, Lodeiro C.

Front Chem. 2018 Nov 27;6:554. doi: 10.3389/fchem.2018.00554. eCollection 2018.


A turnaround strategy: improving equity in order to achieve quality of care and financial sustainability in Italy.

Cafagna G, Seghieri C, Vainieri M, Nuti S.

Int J Equity Health. 2018 Nov 20;17(1):169. doi: 10.1186/s12939-018-0878-x.


Building medical knowledge from real world registries: The case of heart failure.

Aimo A, Seghieri C, Nuti S, Emdin M.

Int J Cardiol Heart Vasc. 2018 Apr 10;19:98-99. doi: 10.1016/j.ijcha.2018.03.008. eCollection 2018 Jun. No abstract available.


Socio-demographic determinants of women's satisfaction with prenatal and delivery care services in Italy.

Tocchioni V, Seghieri C, De Santis G, Nuti S.

Int J Qual Health Care. 2018 Oct 1;30(8):594-601. doi: 10.1093/intqhc/mzy078.


Rethinking Healthcare Performance Evaluation Systems towards the People-Centredness Approach: Their Pathways, their Experience, their Evaluation.

Nuti S, De Rosis S, Bonciani M, Murante AM.

Healthc Pap. 2017 Oct;17(2):56-64. doi: 10.12927/hcpap.2017.25408.


Reputations count: why benchmarking performance is improving health care across the world.

Bevan G, Evans A, Nuti S.

Health Econ Policy Law. 2019 Apr;14(2):141-161. doi: 10.1017/S1744133117000561. Epub 2018 Mar 16.


Insights on the effectiveness of reward schemes from 10-year longitudinal case studies in 2 Italian regions.

Vainieri M, Lungu DA, Nuti S.

Int J Health Plann Manage. 2018 Apr;33(2):e474-e484. doi: 10.1002/hpm.2496. Epub 2018 Jan 30.


Patient satisfaction, patients leaving hospital against medical advice and mortality in Italian university hospitals: a cross-sectional analysis.

Grillo Ruggieri T, Berta P, Murante AM, Nuti S.

BMC Health Serv Res. 2018 Jan 29;18(1):51. doi: 10.1186/s12913-018-2846-y.


Are non-ST-segment elevation myocardial infarctions missing in China?

Murugiah K, Wang Y, Nuti SV, Li X, Li J, Zheng X, Downing NS, Desai NR, Masoudi FA, Spertus JA, Jiang L, Krumholz HM; China PEACE Collaborative Group.

Eur Heart J Qual Care Clin Outcomes. 2017 Oct 1;3(4):319-327. doi: 10.1093/ehjqcco/qcx025.


Quality of Care in the United States Territories, 1999-2012.

Nuti SV, Wang Y, Masoudi FA, Nunez-Smith M, Normand ST, Murugiah K, Rodríguez-Vilá O, Ross JS, Krumholz HM.

Med Care. 2017 Oct;55(10):886-892. doi: 10.1097/MLR.0000000000000797.


Public strategies for improving eHealth integration and long-term sustainability in public health care systems: Findings from an Italian case study.

De Rosis S, Nuti S.

Int J Health Plann Manage. 2018 Jan;33(1):e131-e152. doi: 10.1002/hpm.2443. Epub 2017 Aug 8.


Catching and monitoring clinical innovation through performance indicators. The case of the breast-conserving surgery indicator.

Murante AM, Candelori S, Rucci P, Nuti S, Roncella M, Ghilli M, Mercatelli A, Fantini MP.

BMC Res Notes. 2017 Jul 17;10(1):288. doi: 10.1186/s13104-017-2597-6.


Comparing regional models of congenital bleeding disorders: preliminary steps in the Italian context.

Nuti S, Seghieri C, Niccolai F, Vasta F, Grazzini G.

BMC Res Notes. 2017 Jun 26;10(1):229. doi: 10.1186/s13104-017-2552-6.


Quality of Care in Chinese Hospitals: Processes and Outcomes After ST-segment Elevation Myocardial Infarction.

Downing NS, Wang Y, Dharmarajan K, Nuti SV, Murugiah K, Du X, Zheng X, Li X, Li J, Masoudi FA, Spertus JA, Jiang L, Krumholz HM.

J Am Heart Assoc. 2017 Jun 23;6(6). pii: e005040. doi: 10.1161/JAHA.116.005040.


Explaining performance in health care: How and when top management competencies make the difference.

Vainieri M, Ferrè F, Giacomelli G, Nuti S.

Health Care Manage Rev. 2019 Oct/Dec;44(4):306-317. doi: 10.1097/HMR.0000000000000164.


Sex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial Infarction: A Prospective Observational Study.

Dreyer RP, Dharmarajan K, Kennedy KF, Jones PG, Vaccarino V, Murugiah K, Nuti SV, Smolderen KG, Buchanan DM, Spertus JA, Krumholz HM.

Circulation. 2017 Feb 7;135(6):521-531. doi: 10.1161/CIRCULATIONAHA.116.024993.


How to set challenging goals and conduct fair evaluation in regional public health systems. Insights from Valencia and Tuscany Regions.

Vainieri M, Vola F, Gomez Soriano G, Nuti S.

Health Policy. 2016 Nov;120(11):1270-1278. doi: 10.1016/j.healthpol.2016.09.011. Epub 2016 Sep 24. Review.


Community Level Association between Home Health and Nursing Home Performance on Quality and Hospital 30-day Readmissions for Medicare Patients.

Wang Y, Pandolfi MM, Fine J, Metersky ML, Wang C, Ho SY, Galusha D, Nuti SV, Murugiah K, Spenard A, Elwell T, Krumholz HM.

Home Health Care Manag Pract. 2016 Nov;28(4):201-208. Epub 2016 Apr 7.


Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination.

Corrado A, Donato P, Maccari S, Cecchi R, Spadafina T, Arcidiacono L, Tavarini S, Sammicheli C, Laera D, Manetti AG, Ruggiero P, Galletti B, Nuti S, De Gregorio E, Bertholet S, Seubert A, Bagnoli F, Bensi G, Chiarot E.

Sci Rep. 2016 Nov 30;6:38043. doi: 10.1038/srep38043.


Healthcare Disparities Affecting Americans in the US Territories: A Century-Old Dilemma.

Rodríguez-Vilá O, Nuti SV, Krumholz HM.

Am J Med. 2017 Feb;130(2):e39-e42. doi: 10.1016/j.amjmed.2016.07.036. Epub 2016 Sep 2. No abstract available.


Do university hospitals perform better than general hospitals? A comparative analysis among Italian regions.

Nuti S, Grillo Ruggieri T, Podetti S.

BMJ Open. 2016 Aug 9;6(8):e011426. doi: 10.1136/bmjopen-2016-011426.


Outcome After Admission at Veterans Affairs vs Non-Veterans Affairs Hospitals--Reply.

Nuti SV, Qin L, Krumholz HM.

JAMA. 2016 Jul 19;316(3):346. doi: 10.1001/jama.2016.5394. No abstract available.


Association Between Hospital Performance on Patient Safety and 30-Day Mortality and Unplanned Readmission for Medicare Fee-for-Service Patients With Acute Myocardial Infarction.

Wang Y, Eldridge N, Metersky ML, Sonnenfeld N, Fine JM, Pandolfi MM, Eckenrode S, Bakullari A, Galusha DH, Jaser L, Verzier NR, Nuti SV, Hunt D, Normand SL, Krumholz HM.

J Am Heart Assoc. 2016 Jul 12;5(7). pii: e003731. doi: 10.1161/JAHA.116.003731.


Bridging the Gap between Theory and Practice in Integrated Care: The Case of the Diabetic Foot Pathway in Tuscany.

Nuti S, Bini B, Ruggieri TG, Piaggesi A, Ricci L.

Int J Integr Care. 2016 May 24;16(2):9. doi: 10.5334/ijic.1991.


Carrier priming effect of CRM197 is related to an enhanced B and T cell activation in meningococcal serogroup A conjugate vaccination. Immunological comparison between CRM197 and diphtheria toxoid.

Pecetta S, Tontini M, Faenzi E, Cioncada R, Proietti D, Seubert A, Nuti S, Berti F, Romano MR.

Vaccine. 2016 Apr 29;34(20):2334-41. doi: 10.1016/j.vaccine.2016.03.055. Epub 2016 Mar 23.


Association of Admission to Veterans Affairs Hospitals vs Non-Veterans Affairs Hospitals With Mortality and Readmission Rates Among Older Men Hospitalized With Acute Myocardial Infarction, Heart Failure, or Pneumonia.

Nuti SV, Qin L, Rumsfeld JS, Ross JS, Masoudi FA, Normand SL, Murugiah K, Bernheim SM, Suter LG, Krumholz HM.

JAMA. 2016 Feb 9;315(6):582-92. doi: 10.1001/jama.2016.0278.


One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.

Mancini F, Monaci E, Lofano G, Torre A, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Galletti B, Laera D, Pallaoro M, Tuscano G, Fontana MR, Bensi G, Grandi G, Rossi-Paccani S, Nuti S, Rappuoli R, De Gregorio E, Bagnoli F, Soldaini E, Bertholet S.

PLoS One. 2016 Jan 26;11(1):e0147767. doi: 10.1371/journal.pone.0147767. eCollection 2016.


Fibrinolytic therapy in hospitals without percutaneous coronary intervention capabilities in China from 2001 to 2011: China PEACE-retrospective AMI study.

Li J, Li X, Ross JS, Wang Q, Wang Y, Desai NR, Xu X, Nuti SV, Masoudi FA, Spertus JA, Krumholz HM, Jiang L; China PEACE Collaborative Group.

Eur Heart J Acute Cardiovasc Care. 2017 Apr;6(3):232-243. doi: 10.1177/2048872615626656. Epub 2016 Jan 19.


Trends in Short- and Long-Term Outcomes for Takotsubo Cardiomyopathy Among Medicare Fee-for-Service Beneficiaries, 2007 to 2012.

Murugiah K, Wang Y, Desai NR, Spatz ES, Nuti SV, Dreyer RP, Krumholz HM.

JACC Heart Fail. 2016 Mar;4(3):197-205. doi: 10.1016/j.jchf.2015.09.013. Epub 2015 Dec 30.


Use of Observation Stays in Calculating Hospitalizations Among Medicare Beneficiaries--Reply.

Krumholz HM, Nuti SV, Wang Y.

JAMA. 2015 Dec 22-29;314(24):2691. doi: 10.1001/jama.2015.15064. No abstract available.


Hospital Variation in Outcomes for Transcatheter Aortic Valve Replacement Among Medicare Beneficiaries, 2011 to 2013.

Murugiah K, Wang Y, Desai NR, Nuti SV, Krumholz HM.

J Am Coll Cardiol. 2015 Dec 15;66(23):2678-2679. doi: 10.1016/j.jacc.2015.10.008. No abstract available.


MF59- and Al(OH)3-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers.

Monaci E, Mancini F, Lofano G, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Giraldi M, Galletti B, Rossi Paccani S, Torre A, Fontana MR, Grandi G, de Gregorio E, Bensi G, Chiarot E, Nuti S, Bagnoli F, Soldaini E, Bertholet S.

Front Immunol. 2015 Sep 7;6:439. doi: 10.3389/fimmu.2015.00439. eCollection 2015.


Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013.

Krumholz HM, Nuti SV, Downing NS, Normand SL, Wang Y.

JAMA. 2015 Jul 28;314(4):355-65. doi: 10.1001/jama.2015.8035. Erratum in: JAMA. 2015 Aug 25;314(8):837.


Oil-in-Water Emulsion MF59 Increases Germinal Center B Cell Differentiation and Persistence in Response to Vaccination.

Lofano G, Mancini F, Salvatore G, Cantisani R, Monaci E, Carrisi C, Tavarini S, Sammicheli C, Rossi Paccani S, Soldaini E, Laera D, Finco O, Nuti S, Rappuoli R, De Gregorio E, Bagnoli F, Bertholet S.

J Immunol. 2015 Aug 15;195(4):1617-27. doi: 10.4049/jimmunol.1402604. Epub 2015 Jul 13.


National Quality Assessment of Early Clopidogrel Therapy in Chinese Patients With Acute Myocardial Infarction (AMI) in 2006 and 2011: Insights From the China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE)-Retrospective AMI Study.

Zhang L, Desai NR, Li J, Hu S, Wang Q, Li X, Masoudi FA, Spertus JA, Nuti SV, Wang S, Krumholz HM, Jiang L; China PEACE Collaborative Group.

J Am Heart Assoc. 2015 Jul 10;4(7). pii: e001906. doi: 10.1161/JAHA.115.001906.


National Trends in Hospital Readmission Rates among Medicare Fee-for-Service Survivors of Mitral Valve Surgery, 1999-2010.

Dodson JA, Wang Y, Murugiah K, Dharmarajan K, Cooper Z, Hashim S, Nuti SV, Spatz E, Desai N, Krumholz HM.

PLoS One. 2015 Jul 6;10(7):e0132470. doi: 10.1371/journal.pone.0132470. eCollection 2015.


Sex Differences in the Rate, Timing, and Principal Diagnoses of 30-Day Readmissions in Younger Patients with Acute Myocardial Infarction.

Dreyer RP, Ranasinghe I, Wang Y, Dharmarajan K, Murugiah K, Nuti SV, Hsieh AF, Spertus JA, Krumholz HM.

Circulation. 2015 Jul 21;132(3):158-66. doi: 10.1161/CIRCULATIONAHA.114.014776. Epub 2015 Jun 17.

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