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Items: 9


Mammalian amyloidogenic proteins promote prion nucleation in yeast.

Chandramowlishwaran P, Sun M, Casey KL, Romanyuk AV, Grizel AV, Sopova JV, Rubel AA, Nussbaum-Krammer C, Vorberg IM, Chernoff YO.

J Biol Chem. 2018 Mar 2;293(9):3436-3450. doi: 10.1074/jbc.M117.809004. Epub 2018 Jan 12.


Shape matters: the complex relationship between aggregation and toxicity in protein-misfolding diseases.

Ries HM, Nussbaum-Krammer C.

Essays Biochem. 2016 Oct 15;60(2):181-190. Review.


Proximity mapping of human separase by the BioID approach.

Agircan FG, Hata S, Nussbaum-Krammer C, Atorino E, Schiebel E.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):656-62. doi: 10.1016/j.bbrc.2016.08.002. Epub 2016 Aug 3.


Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils.

Gao X, Carroni M, Nussbaum-Krammer C, Mogk A, Nillegoda NB, Szlachcic A, Guilbride DL, Saibil HR, Mayer MP, Bukau B.

Mol Cell. 2015 Sep 3;59(5):781-93. doi: 10.1016/j.molcel.2015.07.012. Epub 2015 Aug 20.


Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments.

Kirstein J, Morito D, Kakihana T, Sugihara M, Minnen A, Hipp MS, Nussbaum-Krammer C, Kasturi P, Hartl FU, Nagata K, Morimoto RI.

EMBO J. 2015 Sep 14;34(18):2334-49. doi: 10.15252/embj.201591711. Epub 2015 Jul 29.


Investigating the spreading and toxicity of prion-like proteins using the metazoan model organism C. elegans.

Nussbaum-Krammer CI, Neto MF, Brielmann RM, Pedersen JS, Morimoto RI.

J Vis Exp. 2015 Jan 8;(95):52321. doi: 10.3791/52321.


Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases.

Nussbaum-Krammer CI, Morimoto RI.

Dis Model Mech. 2014 Jan;7(1):31-9. doi: 10.1242/dmm.013011. Review.


Spreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegans.

Nussbaum-Krammer CI, Park KW, Li L, Melki R, Morimoto RI.

PLoS Genet. 2013 Mar;9(3):e1003351. doi: 10.1371/journal.pgen.1003351. Epub 2013 Mar 28.


Cell-to-cell propagation of infectious cytosolic protein aggregates.

Hofmann JP, Denner P, Nussbaum-Krammer C, Kuhn PH, Suhre MH, Scheibel T, Lichtenthaler SF, Schätzl HM, Bano D, Vorberg IM.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5951-6. doi: 10.1073/pnas.1217321110. Epub 2013 Mar 18.

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