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Items: 1 to 50 of 311

1.

Polygenic risk scores in psychiatry: Will they be useful for clinicians?

Fullerton JM, Nurnberger JI.

F1000Res. 2019 Jul 31;8. pii: F1000 Faculty Rev-1293. doi: 10.12688/f1000research.18491.1. eCollection 2019. Review.

2.

Entrainment of Circadian Rhythms to Temperature Reveals Amplitude Deficits in Fibroblasts from Patients with Bipolar Disorder and Possible Links to Calcium Channels.

Nudell V, Wei H, Nievergelt C, Maihofer AX, Shilling P, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Covault JM, Frye MA, Gage F, Gershon E, McInnis MG, Nurnberger JI, Oedegaard KJ, Shekhtman T, Zandi PP, Kelsoe JR, McCarthy MJ.

Mol Neuropsychiatry. 2019 Apr;5(2):115-124. doi: 10.1159/000497354. Epub 2019 Apr 4.

PMID:
31192224
3.

A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults.

Chan G, Kramer JR, Schuckit MA, Hesselbrock V, Bucholz KK, Edenberg HJ, Acion L, Langbehn D, McCutcheon V, Nurnberger JI Jr, Hesselbrock M, Porjesz B, Bierut L, Marenna BC, Cookman A, Kuperman S.

Alcohol Clin Exp Res. 2019 Aug;43(8):1759-1768. doi: 10.1111/acer.14116. Epub 2019 Jun 30.

PMID:
31141183
4.

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans.

Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI Jr, Schuckit M, Scott DM, Taylor RE, Tischfield J, Porjesz B, Goate AM, Edenberg HJ, Foroud T, Bogdan R, Agrawal A.

Genes Brain Behav. 2019 Jul;18(6):e12580. doi: 10.1111/gbb.12580. Epub 2019 Jun 11.

PMID:
31099175
5.

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria.

Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI Jr, Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hariri AR, Edenberg HJ, Agrawal A, Bogdan R, Porjesz B, Goate AM, Foroud T.

Genes Brain Behav. 2019 Jul;18(6):e12579. doi: 10.1111/gbb.12579. Epub 2019 Jun 4.

PMID:
31090166
6.

Patterns and predictors of family environment among adolescents at high and low risk for familial bipolar disorder.

Stapp EK, Musci RJ, Fullerton JM, Glowinski AL, McInnis M, Mitchell PB, Hulvershorn LA, Ghaziuddin N, Roberts GMP, Merikangas KR, Nurnberger JI Jr, Wilcox HC.

J Psychiatr Res. 2019 Jul;114:153-160. doi: 10.1016/j.jpsychires.2019.05.003. Epub 2019 May 3.

PMID:
31078786
7.

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, Bækvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, Bøen E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvsåshagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Frisén L, Gade K, Gage D, Garnham J, Giambartolomei C, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS, Juréus A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, Mühleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O'Donovan C, Loohuis LMO, Ori APS, Oruc L, Ösby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P, Ruderfer DM, Ryu E, Sánchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, Søholm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Zöllner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, Børglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, Müller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, Nöthen MM, O'Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribasés M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.

Nat Genet. 2019 May;51(5):793-803. doi: 10.1038/s41588-019-0397-8. Epub 2019 May 1.

PMID:
31043756
8.

In memoriam: Ting-Kai Li (1934-2018).

Nurnberger JI Jr, O'Connor S, Cloninger CR.

Psychiatr Genet. 2019 Jun;29(3):95-96. doi: 10.1097/YPG.0000000000000223. No abstract available.

PMID:
30998619
9.

Dr Nurnberger and Colleagues Reply.

Nurnberger JI Jr, Austin J, Berrettini WH, Besterman AD, DeLisi LE, Grice DE, Kennedy JL, Moreno-De-Luca D, Potash JB, Ross DA, Schulze TG, Zai G.

J Clin Psychiatry. 2019 Apr 9;80(3). pii: 19lr12741a. doi: 10.4088/JCP.19lr12741a. No abstract available.

10.

The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample.

Johnson EC, St Pierre CL, Meyers JL, Aliev F, McCutcheon VV, Lai D, Dick DM, Goate AM, Kramer J, Kuperman S, Nurnberger JI Jr, Schuckit MA, Porjesz B, Edenberg HJ, Bucholz KK, Agrawal A.

Alcohol Clin Exp Res. 2019 Jun;43(6):1113-1125. doi: 10.1111/acer.14064. Epub 2019 May 21.

11.

21st-Century Genetics in Psychiatric Residency Training: How Do We Get There?

Besterman AD, Moreno-De-Luca D, Nurnberger JI Jr.

JAMA Psychiatry. 2019 Mar 1;76(3):231-232. doi: 10.1001/jamapsychiatry.2018.3872. No abstract available.

PMID:
30601877
12.

What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics.

Nurnberger JI Jr, Austin J, Berrettini WH, Besterman AD, DeLisi LE, Grice DE, Kennedy JL, Moreno-De-Luca D, Potash JB, Ross DA, Schulze TG, Zai G.

J Clin Psychiatry. 2018 Nov 27;80(1). pii: 17nr12046. doi: 10.4088/JCP.17nr12046.

13.

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder.

Budde M, Friedrichs S, Alliey-Rodriguez N, Ament S, Badner JA, Berrettini WH, Bloss CS, Byerley W, Cichon S, Comes AL, Coryell W, Craig DW, Degenhardt F, Edenberg HJ, Foroud T, Forstner AJ, Frank J, Gershon ES, Goes FS, Greenwood TA, Guo Y, Hipolito M, Hood L, Keating BJ, Koller DL, Lawson WB, Liu C, Mahon PB, McInnis MG, McMahon FJ, Meier SM, Mühleisen TW, Murray SS, Nievergelt CM, Nurnberger JI Jr, Nwulia EA, Potash JB, Quarless D, Rice J, Roach JC, Scheftner WA, Schork NJ, Shekhtman T, Shilling PD, Smith EN, Streit F, Strohmaier J, Szelinger S, Treutlein J, Witt SH, Zandi PP, Zhang P, Zöllner S, Bickeböller H, Falkai PG, Kelsoe JR, Nöthen MM, Rietschel M, Schulze TG, Malzahn D.

Eur Neuropsychopharmacol. 2019 Jan;29(1):156-170. doi: 10.1016/j.euroneuro.2018.10.005. Epub 2018 Nov 29.

14.

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder.

McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, Calabrese JR, Calkin CV, Claasen A, Conroy C, Coryell WH, Craig DW, D'Arcangelo N, Demodena A, Djurovic S, Feeder S, Fisher C, Frazier N, Frye MA, Gage FH, Gao K, Garnham J, Gershon ES, Glazer K, Goes F, Goto T, Harrington G, Jakobsen P, Kamali M, Karberg E, Kelly M, Leckband SG, Lohoff F, McInnis MG, Mondimore F, Morken G, Nurnberger JI, Obral S, Oedegaard KJ, Ortiz A, Ritchey M, Ryan K, Schinagle M, Schoeyen H, Schwebel C, Shaw M, Shekhtman T, Slaney C, Stapp E, Szelinger S, Tarwater B, Zandi PP, Kelsoe JR.

Neuropsychopharmacology. 2019 Feb;44(3):620-628. doi: 10.1038/s41386-018-0273-8. Epub 2018 Nov 16.

15.

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG; 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A.

Nat Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26.

16.

Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement.

Johnson EC, Tillman R, Aliev F, Meyers JL, Salvatore JE, Anokhin AP, Dick DM, Edenberg HJ, Kramer JR, Kuperman S, McCutcheon VV, Nurnberger JI Jr, Porjesz B, Schuckit MA, Tischfield J, Bucholz KK, Agrawal A.

Addiction. 2019 Apr;114(4):687-697. doi: 10.1111/add.14512. Epub 2019 Jan 1.

PMID:
30474892
17.

Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective.

Su J, Kuo SI, Aliev F, Guy MC, Derlan CL, Edenberg HJ, Nurnberger JI Jr, Kramer JR, Bucholz KK, Salvatore JE, Dick DM.

Alcohol Clin Exp Res. 2018 Sep;42(9):1783-1794. doi: 10.1111/acer.13827. Epub 2018 Jul 20.

18.

Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder.

McLean CK, Narayan S, Lin SY, Rai N, Chung Y, Hipolito MS, Cascella NG, Nurnberger JI Jr, Ishizuka K, Sawa AS, Nwulia EA.

Transl Psychiatry. 2018 Apr 18;8(1):81. doi: 10.1038/s41398-018-0126-6.

19.

A Biomarker Characterizing Neurodevelopment with applications in Autism.

Wu D, José JV, Nurnberger JI, Torres EB.

Sci Rep. 2018 Jan 12;8(1):614. doi: 10.1038/s41598-017-18902-w.

20.

Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts.

Wilcox HC, Fullerton JM, Glowinski AL, Benke K, Kamali M, Hulvershorn LA, Stapp EK, Edenberg HJ, Roberts GMP, Ghaziuddin N, Fisher C, Brucksch C, Frankland A, Toma C, Shaw AD, Kastelic E, Miller L, McInnis MG, Mitchell PB, Nurnberger JI Jr.

J Am Acad Child Adolesc Psychiatry. 2017 Dec;56(12):1073-1080. doi: 10.1016/j.jaac.2017.09.428. Epub 2017 Oct 10.

21.

Genome-wide association study identifies a novel locus for cannabis dependence.

Agrawal A, Chou YL, Carey CE, Baranger DAA, Zhang B, Sherva R, Wetherill L, Kapoor M, Wang JC, Bertelsen S, Anokhin AP, Hesselbrock V, Kramer J, Lynskey MT, Meyers JL, Nurnberger JI, Rice JP, Tischfield J, Bierut LJ, Degenhardt L, Farrer LA, Gelernter J, Hariri AR, Heath AC, Kranzler HR, Madden PAF, Martin NG, Montgomery GW, Porjesz B, Wang T, Whitfield JB, Edenberg HJ, Foroud T, Goate AM, Bogdan R, Nelson EC.

Mol Psychiatry. 2018 May;23(5):1293-1302. doi: 10.1038/mp.2017.200. Epub 2017 Nov 7.

22.

Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?

Hulvershorn LA, King J, Monahan PO, Wilcox HC, Mitchell PB, Fullerton JM, Edenberg HJ, Roberts GMP, Kamali M, Glowinski AL, Ghaziuddin N, McInnis M, Iyer-Eimerbrink PA, Nurnberger JI Jr.

Compr Psychiatry. 2017 Oct;78:130-139. doi: 10.1016/j.comppsych.2017.07.010. Epub 2017 Jul 27.

23.

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence.

Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI Jr, Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, Porjesz B, Dick DM, Hesselbrock V, Boerwinkle E, Southwick SM, Krystal JH, Weissman MM, Levinson DF, Potash JB, Gelernter J, Han S.

JAMA Psychiatry. 2017 Nov 1;74(11):1153-1160. doi: 10.1001/jamapsychiatry.2017.2269.

24.

Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families.

McCutcheon VV, Agrawal A, Kuo SI, Su J, Dick DM, Meyers JL, Edenberg HJ, Nurnberger JI, Kramer JR, Kuperman S, Schuckit MA, Hesselbrock VM, Brooks A, Porjesz B, Bucholz KK.

Addiction. 2018 Feb;113(2):336-345. doi: 10.1111/add.14003. Epub 2017 Sep 6.

25.

A Genetic Locus Associated With Depression: The Iceberg Begins to Melt.

Nurnberger JI Jr.

Biol Psychiatry. 2017 Sep 1;82(5):304-305. doi: 10.1016/j.biopsych.2017.06.023. No abstract available.

PMID:
28781002
26.

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT, Bellivier F, Bergen S, Bethell A, Biernacka JM, Blackwood DHR, Boks MP, Boomsma DI, Børglum AD, Borrmann-Hassenbach M, Brennan P, Budde M, Buttenschøn HN, Byrne EM, Cervantes P, Clarke TK, Craddock N, Cruceanu C, Curtis D, Czerski PM, Dannlowski U, Davis T, de Geus EJC, Di Florio A, Djurovic S, Domenici E, Edenberg HJ, Etain B, Fischer SB, Forty L, Fraser C, Frye MA, Fullerton JM, Gade K, Gershon ES, Giegling I, Gordon SD, Gordon-Smith K, Grabe HJ, Green EK, Greenwood TA, Grigoroiu-Serbanescu M, Guzman-Parra J, Hall LS, Hamshere M, Hauser J, Hautzinger M, Heilbronner U, Herms S, Hitturlingappa S, Hoffmann P, Holmans P, Hottenga JJ, Jamain S, Jones I, Jones LA, Juréus A, Kahn RS, Kammerer-Ciernioch J, Kirov G, Kittel-Schneider S, Kloiber S, Knott SV, Kogevinas M, Landén M, Leber M, Leboyer M, Li QS, Lissowska J, Lucae S, Martin NG, Mayoral-Cleries F, McElroy SL, McIntosh AM, McKay JD, McQuillin A, Medland SE, Middeldorp CM, Milaneschi Y, Mitchell PB, Montgomery GW, Morken G, Mors O, Mühleisen TW, Müller-Myhsok B, Myers RM, Nievergelt CM, Nurnberger JI, O'Donovan MC, Loohuis LMO, Ophoff R, Oruc L, Owen MJ, Paciga SA, Penninx BWJH, Perry A, Pfennig A, Potash JB, Preisig M, Reif A, Rivas F, Rouleau GA, Schofield PR, Schulze TG, Schwarz M, Scott L, Sinnamon GCB, Stahl EA, Strauss J, Turecki G, Van der Auwera S, Vedder H, Vincent JB, Willemsen G, Witt CC, Wray NR, Xi HS; Bipolar Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tadic A, Dahmen N, Schott BH, Cichon S, Nöthen MM, Ripke S, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Rietschel M.

Transl Psychiatry. 2017 Jun 20;7(6):e1155. doi: 10.1038/tp.2017.115.

27.

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression.

Culverhouse RC, Saccone NL, Horton AC, Ma Y, Anstey KJ, Banaschewski T, Burmeister M, Cohen-Woods S, Etain B, Fisher HL, Goldman N, Guillaume S, Horwood J, Juhasz G, Lester KJ, Mandelli L, Middeldorp CM, Olié E, Villafuerte S, Air TM, Araya R, Bowes L, Burns R, Byrne EM, Coffey C, Coventry WL, Gawronski KAB, Glei D, Hatzimanolis A, Hottenga JJ, Jaussent I, Jawahar C, Jennen-Steinmetz C, Kramer JR, Lajnef M, Little K, Zu Schwabedissen HM, Nauck M, Nederhof E, Petschner P, Peyrot WJ, Schwahn C, Sinnamon G, Stacey D, Tian Y, Toben C, Van der Auwera S, Wainwright N, Wang JC, Willemsen G, Anderson IM, Arolt V, Åslund C, Bagdy G, Baune BT, Bellivier F, Boomsma DI, Courtet P, Dannlowski U, de Geus EJC, Deakin JFW, Easteal S, Eley T, Fergusson DM, Goate AM, Gonda X, Grabe HJ, Holzman C, Johnson EO, Kennedy M, Laucht M, Martin NG, Munafò MR, Nilsson KW, Oldehinkel AJ, Olsson CA, Ormel J, Otte C, Patton GC, Penninx BWJH, Ritchie K, Sarchiapone M, Scheid JM, Serretti A, Smit JH, Stefanis NC, Surtees PG, Völzke H, Weinstein M, Whooley M, Nurnberger JI Jr, Breslau N, Bierut LJ.

Mol Psychiatry. 2018 Jan;23(1):133-142. doi: 10.1038/mp.2017.44. Epub 2017 Apr 4.

28.

Autism genetics: opportunities and challenges for clinical translation.

Vorstman JAS, Parr JR, Moreno-De-Luca D, Anney RJL, Nurnberger JI Jr, Hallmayer JF.

Nat Rev Genet. 2017 Jun;18(6):362-376. doi: 10.1038/nrg.2017.4. Epub 2017 Mar 6. Review.

PMID:
28260791
29.

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism.

Agrawal A, Tillman R, Grucza RA, Nelson EC, McCutcheon VV, Few L, Conner KR, Lynskey MT, Dick DM, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI Jr, Schuckit MA, Porjesz B, Bucholz KK.

J Affect Disord. 2017 Apr 15;213:96-104. doi: 10.1016/j.jad.2016.12.060. Epub 2017 Feb 3.

30.

Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study.

Bucholz KK, McCutcheon VV, Agrawal A, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI Jr, Salvatore JE, Schuckit MA, Bierut LJ, Foroud TM, Chan G, Hesselbrock M, Meyers JL, Edenberg HJ, Porjesz B.

Alcohol Clin Exp Res. 2017 Feb;41(2):359-368. doi: 10.1111/acer.13293. Epub 2017 Jan 10.

31.

A genome wide association study of fast beta EEG in families of European ancestry.

Meyers JL, Zhang J, Manz N, Rangaswamy M, Kamarajan C, Wetherill L, Chorlian DB, Kang SJ, Bauer L, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI Jr, Tischfield J, Wang JC, Edenberg HJ, Goate A, Foroud T, Porjesz B.

Int J Psychophysiol. 2017 May;115:74-85. doi: 10.1016/j.ijpsycho.2016.12.008. Epub 2016 Dec 28.

32.

Effects of Lithium Monotherapy for Bipolar Disorder on Gene Expression in Peripheral Lymphocytes.

Anand A, McClintick JN, Murrell J, Karne H, Nurnberger JI, Edenberg HJ.

Mol Neuropsychiatry. 2016 Oct;2(3):115-123. Epub 2016 Jun 29.

33.

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, Baune BT, Bellivier F, Benabarre A, Bengesser S, Berrettini WH, Bhattacharjee AK, Biernacka JM, Birner A, Bloss CS, Brichant-Petitjean C, Bui ET, Byerley W, Cervantes P, Chillotti C, Cichon S, Colom F, Coryell W, Craig DW, Cruceanu C, Czerski PM, Davis T, Dayer A, Degenhardt F, Del Zompo M, DePaulo JR, Edenberg HJ, Étain B, Falkai P, Foroud T, Forstner AJ, Frisén L, Frye MA, Fullerton JM, Gard S, Garnham JS, Gershon ES, Goes FS, Greenwood TA, Grigoroiu-Serbanescu M, Hauser J, Heilbronner U, Heilmann-Heimbach S, Herms S, Hipolito M, Hitturlingappa S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Koller DL, König B, Lackner N, Laje G, Lang M, Lavebratt C, Lawson WB, Leboyer M, Leckband SG, Liu C, Maaser A, Mahon PB, Maier W, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, McInnis MG, McKinney R, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Mühleisen TW, Nievergelt CM, Nöthen MM, Novák T, Nurnberger JI Jr, Nwulia EA, Ösby U, Pfennig A, Potash JB, Propping P, Reif A, Reininghaus E, Rice J, Rietschel M, Rouleau GA, Rybakowski JK, Schalling M, Scheftner WA, Schofield PR, Schork NJ, Schulze TG, Schumacher J, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Simhandl C, Slaney CM, Smith EN, Squassina A, Stamm T, Stopkova P, Streit F, Strohmaier J, Szelinger S, Tighe SK, Tortorella A, Turecki G, Vieta E, Volkert J, Witt SH, Wright A, Zandi PP, Zhang P, Zollner S, McMahon FJ.

Hum Mol Genet. 2016 Aug 1;25(15):3383-3394. doi: 10.1093/hmg/ddw181. Epub 2016 Jun 21.

34.

Interhemispheric white matter integrity in young people with bipolar disorder and at high genetic risk.

Roberts G, Wen W, Frankland A, Perich T, Holmes-Preston E, Levy F, Lenroot RK, Hadzi-Pavlovic D, Nurnberger JI, Breakspear M, Mitchell PB.

Psychol Med. 2016 Aug;46(11):2385-96. doi: 10.1017/S0033291716001161. Epub 2016 Jun 13.

35.

Transgenerational latent early-life associated regulation unites environment and genetics across generations.

Lahiri DK, Maloney B, Bayon BL, Chopra N, White FA, Greig NH, Nurnberger JI.

Epigenomics. 2016 Mar;8(3):373-87. doi: 10.2217/epi.15.117. Epub 2016 Mar 7.

36.

Toward Precision Psychiatry: Statistical Platform for the Personalized Characterization of Natural Behaviors.

Torres EB, Isenhower RW, Nguyen J, Whyatt C, Nurnberger JI, Jose JV, Silverstein SM, Papathomas TV, Sage J, Cole J.

Front Neurol. 2016 Feb 2;7:8. doi: 10.3389/fneur.2016.00008. eCollection 2016.

37.

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Oedegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J.

Nature. 2016 Feb 11;530(7589):242. doi: 10.1038/nature16182. Epub 2015 Nov 25. No abstract available.

PMID:
26605530
38.

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J.

Nature. 2015 Nov 5;527(7576):95-9. doi: 10.1038/nature15526. Epub 2015 Oct 28. Erratum in: Nature. 2016 Feb 11;530(7589):242. Alba, Martin [Corrected to Alda, Martin].

39.

Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals.

Fullerton JM, Koller DL, Edenberg HJ, Foroud T, Liu H, Glowinski AL, McInnis MG, Wilcox HC, Frankland A, Roberts G, Schofield PR, Mitchell PB, Nurnberger JI; Bipolar High Risk Study Group, BiGS Consortium.

Am J Med Genet B Neuropsychiatr Genet. 2015 Oct;168(7):617-29. doi: 10.1002/ajmg.b.32344. Epub 2015 Jul 16.

40.

Variants in Ion Channel Genes Link Phenotypic Features of Bipolar Illness to Specific Neurobiological Process Domains.

Balaraman Y, Lahiri DK, Nurnberger JI.

Mol Neuropsychiatry. 2015 May;1(1):23-35. doi: 10.1159/000371886. Epub 2015 Feb 20. Review.

41.

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior.

Salvatore JE, Edwards AC, McClintick JN, Bigdeli TB, Adkins A, Aliev F, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Tischfield JA, Xuei X, Dick DM.

Transl Psychiatry. 2015 Apr 28;5:e558. doi: 10.1038/tp.2015.36.

42.

Genetic and childhood trauma interaction effect on age of onset in bipolar disorder: An exploratory analysis.

Anand A, Koller DL, Lawson WB, Gershon ES, Nurnberger JI; BiGS Collaborative.

J Affect Disord. 2015 Jul 1;179:1-5. doi: 10.1016/j.jad.2015.02.029. Epub 2015 Mar 10.

43.

Characteristics of Bipolar I patients grouped by externalizing disorders.

Swaminathan S, Koller DL, Foroud T, Edenberg HJ, Xuei X, Niculescu AB 3rd; Bipolar Genome Study (BiGS) Consortium,, Nurnberger JI Jr.

J Affect Disord. 2015 Jun 1;178:206-14. doi: 10.1016/j.jad.2015.03.011. Epub 2015 Mar 14.

44.

Confirmatory test of two factors and four subtypes of bipolar disorder based on lifetime psychiatric co-morbidity.

Monahan PO, Stump T, Coryell WH, Harezlak J, Marcoulides GA, Liu H, Steeger CM, Mitchell PB, Wilcox HC, Hulvershorn LA, Glowinski AL; Bipolar Disorder Genome Study (BiGS) Consortium, Iyer-Eimerbrink PA, McInnis M, Nurnberger JI.

Psychol Med. 2015 Jul;45(10):2181-96. doi: 10.1017/S0033291715000185. Epub 2015 Mar 31.

45.

Rare variants in neuronal excitability genes influence risk for bipolar disorder.

Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI Jr, Edenberg HJ, Gershon ES, Schork N; Bipolar Genome Study, Price ND, Gelinas R, Hood L, Craig D, McMahon FJ, Kelsoe JR, Roach JC.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3576-81. doi: 10.1073/pnas.1424958112. Epub 2015 Feb 17.

46.

Genetics of alcoholism.

Iyer-Eimerbrink PA, Nurnberger JI Jr.

Curr Psychiatry Rep. 2014 Dec;16(12):518. doi: 10.1007/s11920-014-0518-0. Review.

PMID:
25399692
47.

The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses.

Buxbaum JD, Bolshakova N, Brownfeld JM, Anney RJ, Bender P, Bernier R, Cook EH, Coon H, Cuccaro M, Freitag CM, Hallmayer J, Geschwind D, Klauck SM, Nurnberger JI, Oliveira G, Pinto D, Poustka F, Scherer SW, Shih A, Sutcliffe JS, Szatmari P, Vicente AM, Vieland V, Gallagher L.

Mol Autism. 2014 May 20;5:34. doi: 10.1186/2040-2392-5-34. eCollection 2014.

48.

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.

Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Almasy L, Bucholz K, Dick DM, Harari O, Xiaoling X, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A.

Drug Alcohol Depend. 2014 Sep 1;142:56-62. doi: 10.1016/j.drugalcdep.2014.05.023. Epub 2014 Jun 11.

49.

Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample.

McCutcheon VV, Kramer JR, Edenberg HJ, Nurnberger JI, Kuperman S, Schuckit MA, Heath AC, Bucholz KK.

Alcohol Clin Exp Res. 2014 Jul;38(7):2015-23. doi: 10.1111/acer.12434. Epub 2014 Jun 18.

50.

On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis.

Peterson RE, Maes HH, Lin P, Kramer JR, Hesselbrock VM, Bauer LO, Nurnberger JI Jr, Edenberg HJ, Dick DM, Webb BT.

BMC Genomics. 2014 May 14;15:368. doi: 10.1186/1471-2164-15-368.

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