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Items: 1 to 50 of 78

1.

Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.

Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D 3rd, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF.

J Med Chem. 2019 May 23;62(10):4884-4901. doi: 10.1021/acs.jmedchem.9b00193. Epub 2019 Apr 23.

PMID:
31013090
2.

Setting priorities to address cardiovascular diseases through universal health coverage in low- and middle-income countries.

Watkins DA, Nugent RA.

Heart Asia. 2017 Feb 21;9(1):54-58. doi: 10.1136/heartasia-2015-010690. eCollection 2017. Review.

3.

Health gains and financial risk protection afforded by public financing of selected interventions in Ethiopia: an extended cost-effectiveness analysis.

Verguet S, Olson ZD, Babigumira JB, Desalegn D, Johansson KA, Kruk ME, Levin CE, Nugent RA, Pecenka C, Shrime MG, Memirie ST, Watkins DA, Jamison DT.

Lancet Glob Health. 2015 May;3(5):e288-96. doi: 10.1016/S2214-109X(14)70346-8.

4.

Cardiovascular disease and impoverishment averted due to a salt reduction policy in South Africa: an extended cost-effectiveness analysis.

Watkins DA, Olson ZD, Verguet S, Nugent RA, Jamison DT.

Health Policy Plan. 2016 Feb;31(1):75-82. doi: 10.1093/heapol/czv023. Epub 2015 Apr 3.

5.

The consequences of tobacco tax on household health and finances in rich and poor smokers in China: an extended cost-effectiveness analysis.

Verguet S, Gauvreau CL, Mishra S, MacLennan M, Murphy SM, Brouwer ED, Nugent RA, Zhao K, Jha P, Jamison DT.

Lancet Glob Health. 2015 Apr;3(4):e206-16. doi: 10.1016/S2214-109X(15)70095-1. Epub 2015 Mar 13.

6.

Do we produce enough fruits and vegetables to meet global health need?

Siegel KR, Ali MK, Srinivasiah A, Nugent RA, Narayan KM.

PLoS One. 2014 Aug 6;9(8):e104059. doi: 10.1371/journal.pone.0104059. eCollection 2014.

7.

Novel benzoxazole inhibitors of mPGES-1.

Kablaoui N, Patel S, Shao J, Demian D, Hoffmaster K, Berlioz F, Vazquez ML, Moore WM, Nugent RA.

Bioorg Med Chem Lett. 2013 Feb 1;23(3):907-11. doi: 10.1016/j.bmcl.2012.10.040. Epub 2012 Oct 16.

PMID:
23266122
8.

What can a UN health summit do?

Nugent RA, Jamison DT.

Sci Transl Med. 2011 Sep 14;3(100):100cm25. doi: 10.1126/scitranslmed.3003132.

PMID:
21918103
9.

The burden of chronic kidney disease on developing nations: a 21st century challenge in global health.

Nugent RA, Fathima SF, Feigl AB, Chyung D.

Nephron Clin Pract. 2011;118(3):c269-77. doi: 10.1159/000321382. Epub 2011 Jan 7. Review.

10.

Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility.

Nieman JA, Nair SK, Heasley SE, Schultz BL, Zerth HM, Nugent RA, Chen K, Stephanski KJ, Hopkins TA, Knechtel ML, Oien NL, Wieber JL, Wathen MW.

Bioorg Med Chem Lett. 2010 May 15;20(10):3039-42. doi: 10.1016/j.bmcl.2010.03.115. Epub 2010 Apr 3.

PMID:
20403696
11.

Non-communicable diseases and the Paris Declaration.

Nugent RA, Yach D, Feigl AB.

Lancet. 2009 Sep 5;374(9692):784-5. doi: 10.1016/S0140-6736(09)61589-0. No abstract available.

PMID:
19733778
12.

Structure-guided inhibitor design for human FAAH by interspecies active site conversion.

Mileni M, Johnson DS, Wang Z, Everdeen DS, Liimatta M, Pabst B, Bhattacharya K, Nugent RA, Kamtekar S, Cravatt BF, Ahn K, Stevens RC.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12820-4. doi: 10.1073/pnas.0806121105. Epub 2008 Aug 27.

13.
14.

Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.

Ahn K, Johnson DS, Fitzgerald LR, Liimatta M, Arendse A, Stevenson T, Lund ET, Nugent RA, Nomanbhoy TK, Alexander JP, Cravatt BF.

Biochemistry. 2007 Nov 13;46(45):13019-30. Epub 2007 Oct 19.

PMID:
17949010
15.

Calcified cerebral emboli.

Kavanagh EC, Fenton DM, Heran MK, Lapointe JS, Nugent RA, Graeb DA.

AJNR Am J Neuroradiol. 2006 Oct;27(9):1996-9.

16.

Diffusion-weighted imaging findings in Balo concentric sclerosis.

Kavanagh EC, Heran MK, Fenton DM, Lapointe JS, Nugent RA, Graeb DA.

Br J Radiol. 2006 Jul;79(943):e28-31.

PMID:
16823051
17.

Adult xanthogranulomatous disease of the orbit and ocular adnexa: new immunohistochemical findings and clinical review.

Sivak-Callcott JA, Rootman J, Rasmussen SL, Nugent RA, White VA, Paridaens D, Currie Z, Rose G, Clark B, McNab AA, Buffam FV, Neigel JM, Kazim M.

Br J Ophthalmol. 2006 May;90(5):602-8. Review.

18.

Barotrauma presenting as temporal lobe injury secondary to temporal bone rupture.

Cortes MD, Longridge NS, Lepawsky M, Nugent RA.

AJNR Am J Neuroradiol. 2005 May;26(5):1218-9.

19.

Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid.

Pfefferkorn JA, Greene ML, Nugent RA, Gross RJ, Mitchell MA, Finzel BC, Harris MS, Wells PA, Shelly JA, Anstadt RA, Kilkuskie RE, Kopta LA, Schwende FJ.

Bioorg Med Chem Lett. 2005 May 16;15(10):2481-6.

PMID:
15863301
20.

Attenuation of social class and reproductive risk factor associations for Hodgkin lymphoma due to selection bias in controls.

Glaser SL, Clarke CA, Keegan TH, Gomez SL, Nugent RA, Topol B, Stearns CB, Stewart SL.

Cancer Causes Control. 2004 Sep;15(7):731-9.

PMID:
15280631
21.

3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding.

Pevarello P, Brasca MG, Amici R, Orsini P, Traquandi G, Corti L, Piutti C, Sansonna P, Villa M, Pierce BS, Pulici M, Giordano P, Martina K, Fritzen EL, Nugent RA, Casale E, Cameron A, Ciomei M, Roletto F, Isacchi A, Fogliatto G, Pesenti E, Pastori W, Marsiglio A, Leach KL, Clare PM, Fiorentini F, Varasi M, Vulpetti A, Warpehoski MA.

J Med Chem. 2004 Jun 17;47(13):3367-80.

PMID:
15189033
22.

Localised invasive sino-orbital aspergillosis: characteristic features.

Sivak-Callcott JA, Livesley N, Nugent RA, Rasmussen SL, Saeed P, Rootman J.

Br J Ophthalmol. 2004 May;88(5):681-7. Review.

23.

Optic nerve sheath meningiomas.

Saeed P, Rootman J, Nugent RA, White VA, Mackenzie IR, Koornneef L.

Ophthalmology. 2003 Oct;110(10):2019-30.

PMID:
14522782
24.

Reproductive factors in Hodgkin's disease in women.

Glaser SL, Clarke CA, Nugent RA, Stearns CB, Dorfman RF.

Am J Epidemiol. 2003 Sep 15;158(6):553-63.

PMID:
12965881
25.
26.

Maternal effects on traits measured during postweaning performance test of swine from four breeds.

Johnson ZB, Chewning JJ, Nugent RA 3rd.

J Anim Sci. 2002 Jun;80(6):1470-7.

PMID:
12078726
27.

Social class and risk of Hodgkin's disease in young-adult women in 1988-94.

Glaser SL, Clarke CA, Nugent RA, Stearns CB, Dorfman RF.

Int J Cancer. 2002 Mar 1;98(1):110-7.

28.

Baló's concentric sclerosis: surviving normal myelin in a patient with a relapsing-remitting dinical course.

Moore GR, Berry K, Oger JJ, Prout AJ, Graeb DA, Nugent RA.

Mult Scler. 2001 Dec;7(6):375-82.

PMID:
11795459
29.

A prospective randomized comparison of CT and MRI pre-operative localization for pallidotomy.

Honey CR, Nugent RA.

Can J Neurol Sci. 2000 Aug;27(3):236-40.

PMID:
10975536
30.

Genetic parameters for production traits and measures of residual feed intake in large white swine.

Johnson ZB, Chewning JJ, Nugent RA 3rd.

J Anim Sci. 1999 Jul;77(7):1679-85.

PMID:
10438012
31.

Anti-inflammatory/antiarthritic ketonic bisphosphonic acid esters.

Schlachter ST, Galinet LA, Shields SK, Aspar DG, Dunn CJ, Staite ND, Nugent RA.

Bioorg Med Chem Lett. 1998 May 5;8(9):1093-6.

PMID:
9871714
32.

Pyrimidine thioethers: a novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV.

Nugent RA, Schlachter ST, Murphy MJ, Cleek GJ, Poel TJ, Wishka DG, Graber DR, Yagi Y, Keiser BJ, Olmsted RA, Kopta LA, Swaney SM, Poppe SM, Morris J, Tarpley WG, Thomas RC.

J Med Chem. 1998 Sep 24;41(20):3793-803.

PMID:
9748354
33.

(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

Wishka DG, Graber DR, Kopta LA, Olmsted RA, Friis JM, Hosley JD, Adams WJ, Seest EP, Castle TM, Dolak LA, Keiser BJ, Yagi Y, Jeganathan A, Schlachter ST, Murphy MJ, Cleek GJ, Nugent RA, Poppe SM, Swaney SM, Han F, Watt W, White WL, Poel TJ, Thomas RC, Morris J, et al.

J Med Chem. 1998 Apr 23;41(9):1357-60. No abstract available.

PMID:
9554867
35.

In vivo measurement of T2 distributions and water contents in normal human brain.

Whittall KP, MacKay AL, Graeb DA, Nugent RA, Li DK, Paty DW.

Magn Reson Med. 1997 Jan;37(1):34-43.

PMID:
8978630
36.

Contrast-enhanced imaging studies contraindicated in patients receiving Glucophage.

Nugent RA, Flak B.

Can Assoc Radiol J. 1996 Jun;47(3):225. No abstract available.

PMID:
8640422
37.

Carbonyl-containing bisphosphonate esters as novel antiinflammatory and antiarthritic agents.

Nugent RA, Schlachter ST, Murphy M, Dunn CJ, Staite ND, Galinet LA, Shields SK, Wu H, Aspar DG, Richard KA.

J Med Chem. 1994 Dec 23;37(26):4449-54.

PMID:
7818726
38.

Demonstration of novel anti-arthritic and anti-inflammatory effects of diphosphonates.

Dunn CJ, Galinet LA, Wu H, Nugent RA, Schlachter ST, Staite ND, Aspar DG, Elliott GA, Essani NA, Rohloff NA, et al.

J Pharmacol Exp Ther. 1993 Sep;266(3):1691-8.

PMID:
8371167
39.

Radiotherapy in the management of thyroid orbitopathy. Computed tomography and clinical outcomes.

Kao SC, Kendler DL, Nugent RA, Adler JS, Rootman J.

Arch Ophthalmol. 1993 Jun;111(6):819-23.

PMID:
8512483
41.

Pyrazoline bisphosphonate esters as novel antiinflammatory and antiarthritic agents.

Nugent RA, Murphy M, Schlachter ST, Dunn CJ, Smith RJ, Staite ND, Galinet LA, Shields SK, Aspar DG, Richard KA, et al.

J Med Chem. 1993 Jan 8;36(1):134-9.

PMID:
8421279
42.

Granulomatous orbital lesions: computed tomographic features.

O'Sullivan RM, Nugent RA, Satorre J, Rootman J.

Can Assoc Radiol J. 1992 Oct;43(5):349-58.

PMID:
1393700
43.

Inadvertent intracranial placement of a nasogastric tube in a patient with severe head trauma.

Adler JS, Graeb DA, Nugent RA.

CMAJ. 1992 Sep 1;147(5):668-9. No abstract available.

45.
46.

Inflammatory pseudotumor of orbit.

Nugent RA.

Clin Radiol. 1992 Aug;46(2):148. No abstract available.

PMID:
1395410
47.
48.

Orbital lesions with granulomatous inflammation.

Satorre J, Antle CM, O'Sullivan R, White VA, Nugent RA, Rootman J.

Can J Ophthalmol. 1991 Jun;26(4):174-95.

PMID:
1889019
50.

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