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Items: 1 to 50 of 118

1.

iRAPs curb antisense transcription in E. coli.

Magán A, Amman F, El-Isa F, Hartl N, Shamovsky I, Nudler E, Schroeder R, Sedlyarova N.

Nucleic Acids Res. 2019 Sep 19. pii: gkz791. doi: 10.1093/nar/gkz791. [Epub ahead of print]

PMID:
31535128
2.

The Molecular Architecture of Native BBSome Obtained by an Integrated Structural Approach.

Chou HT, Apelt L, Farrell DP, White SR, Woodsmith J, Svetlov V, Goldstein JS, Nager AR, Li Z, Muller J, Dollfus H, Nudler E, Stelzl U, DiMaio F, Nachury MV, Walz T.

Structure. 2019 Sep 3;27(9):1384-1394.e4. doi: 10.1016/j.str.2019.06.006. Epub 2019 Jul 11.

PMID:
31303482
3.

Transcription factor YcjW controls the emergency H2S production in E. coli.

Luhachack L, Rasouly A, Shamovsky I, Nudler E.

Nat Commun. 2019 Jun 28;10(1):2868. doi: 10.1038/s41467-019-10785-x.

4.

Paf1C regulates RNA polymerase II progression by modulating elongation rate.

Hou L, Wang Y, Liu Y, Zhang N, Shamovsky I, Nudler E, Tian B, Dynlacht BD.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14583-14592. doi: 10.1073/pnas.1904324116. Epub 2019 Jun 27.

5.

Reactive oxygen species as the long arm of bactericidal antibiotics.

Rasouly A, Nudler E.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):9696-9698. doi: 10.1073/pnas.1905291116. Epub 2019 May 6. No abstract available.

PMID:
31061135
6.

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.

Valencia-Sánchez MI, De Ioannes P, Wang M, Vasilyev N, Chen R, Nudler E, Armache JP, Armache KJ.

Mol Cell. 2019 Jun 6;74(5):1010-1019.e6. doi: 10.1016/j.molcel.2019.03.029. Epub 2019 Apr 10.

PMID:
30981630
7.

Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer.

Schneider JA, Craven TW, Kasper AC, Yun C, Haugbro M, Briggs EM, Svetlov V, Nudler E, Knaut H, Bonneau R, Garabedian MJ, Kirshenbaum K, Logan SK.

Nat Commun. 2018 Oct 23;9(1):4396. doi: 10.1038/s41467-018-06845-3.

8.

H2S, a Bacterial Defense Mechanism against the Host Immune Response.

Toliver-Kinsky T, Cui W, Törö G, Lee SJ, Shatalin K, Nudler E, Szabo C.

Infect Immun. 2018 Dec 19;87(1). pii: e00272-18. doi: 10.1128/IAI.00272-18. Print 2019 Jan.

9.

Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.

Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA.

Nat Struct Mol Biol. 2018 Jul;25(7):616-622. doi: 10.1038/s41594-018-0085-x. Epub 2018 Jul 2.

10.

Variation in FPOP Measurements Is Primarily Caused by Poor Peptide Signal Intensity.

Abolhasani Khaje N, Mobley CK, Misra SK, Miller L, Li Z, Nudler E, Sharp JS.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1901-1907. doi: 10.1007/s13361-018-1994-y. Epub 2018 Jun 25.

11.

Glycogen at the Crossroad of Stress Resistance, Energy Maintenance, and Pathophysiology of Aging.

Gusarov I, Nudler E.

Bioessays. 2018 Sep;40(9):e1800033. doi: 10.1002/bies.201800033. Epub 2018 Jun 13. Review.

PMID:
29897131
12.

Reading of the non-template DNA by transcription elongation factors.

Svetlov V, Nudler E.

Mol Microbiol. 2018 Aug;109(4):417-421. doi: 10.1111/mmi.13984.

13.

New HSF1 inducer as a therapeutic agent in a rodent model of Parkinson's disease.

Ekimova IV, Plaksina DV, Pastukhov YF, Lapshina KV, Lazarev VF, Mikhaylova ER, Polonik SG, Pani B, Margulis BA, Guzhova IV, Nudler E.

Exp Neurol. 2018 Aug;306:199-208. doi: 10.1016/j.expneurol.2018.04.012. Epub 2018 Apr 26.

PMID:
29704482
14.

Antibiotic killing through oxidized nucleotides.

Rasouly A, Nudler E.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):1967-1969. doi: 10.1073/pnas.1800255115. Epub 2018 Feb 14. No abstract available.

15.

Protein S-Nitrosylation: Enzymatically Controlled, but Intrinsically Unstable, Post-translational Modification.

Gusarov I, Nudler E.

Mol Cell. 2018 Feb 1;69(3):351-353. doi: 10.1016/j.molcel.2018.01.022.

16.

Structure of RNA polymerase bound to ribosomal 30S subunit.

Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev AA.

Elife. 2017 Oct 13;6. pii: e28560. doi: 10.7554/eLife.28560.

17.

Mechanism of biofilm-mediated stress resistance and lifespan extension in C. elegans.

Smolentseva O, Gusarov I, Gautier L, Shamovsky I, DeFrancesco AS, Losick R, Nudler E.

Sci Rep. 2017 Aug 2;7(1):7137. doi: 10.1038/s41598-017-07222-8.

18.

Natural RNA Polymerase Aptamers Regulate Transcription in E. coli.

Sedlyarova N, Rescheneder P, Magán A, Popitsch N, Rziha N, Bilusic I, Epshtein V, Zimmermann B, Lybecker M, Sedlyarov V, Schroeder R, Nudler E.

Mol Cell. 2017 Jul 6;67(1):30-43.e6. doi: 10.1016/j.molcel.2017.05.025. Epub 2017 Jun 22.

19.

Strategies and Methods of Transcription-Coupled Repair Studies In Vitro and In Vivo.

Epshtein V, Kamarthapu V, Nudler E.

Methods Enzymol. 2017;591:287-306. doi: 10.1016/bs.mie.2017.03.014. Epub 2017 May 3.

PMID:
28645373
20.

Mechanistic insights into transcription coupled DNA repair.

Pani B, Nudler E.

DNA Repair (Amst). 2017 Aug;56:42-50. doi: 10.1016/j.dnarep.2017.06.006. Epub 2017 Jun 9. Review.

21.

Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress.

Gusarov I, Pani B, Gautier L, Smolentseva O, Eremina S, Shamovsky I, Katkova-Zhukotskaya O, Mironov A, Nudler E.

Nat Commun. 2017 Jun 19;8:15868. doi: 10.1038/ncomms15868.

22.

Mechanism of H2S-mediated protection against oxidative stress in Escherichia coli.

Mironov A, Seregina T, Nagornykh M, Luhachack LG, Korolkova N, Lopes LE, Kotova V, Zavilgelsky G, Shakulov R, Shatalin K, Nudler E.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6022-6027. doi: 10.1073/pnas.1703576114. Epub 2017 May 22.

23.

A Magic Spot in Genome Maintenance.

Rasouly A, Pani B, Nudler E.

Trends Genet. 2017 Jan;33(1):58-67. doi: 10.1016/j.tig.2016.11.002. Epub 2016 Dec 5. Review.

24.

S-nitrosylation of peroxiredoxin 1 contributes to viability of lung epithelial cells during Bacillus anthracis infection.

Chung MC, Alem F, Hamer SG, Narayanan A, Shatalin K, Bailey C, Nudler E, Hakami RM.

Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3019-3029. doi: 10.1016/j.bbagen.2016.09.006. Epub 2016 Sep 7.

PMID:
27612662
25.

sRNA-Mediated Control of Transcription Termination in E. coli.

Sedlyarova N, Shamovsky I, Bharati BK, Epshtein V, Chen J, Gottesman S, Schroeder R, Nudler E.

Cell. 2016 Sep 22;167(1):111-121.e13. doi: 10.1016/j.cell.2016.09.004.

26.

Upregulation of cystathionine β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury.

Lechpammer M, Tran YP, Wintermark P, Martínez-Cerdeño V, Krishnan VV, Ahmed W, Berman RF, Jensen FE, Nudler E, Zagzag D.

Brain Pathol. 2017 Jul;27(4):449-458. doi: 10.1111/bpa.12421. Epub 2016 Aug 28. Erratum in: Brain Pathol. 2017 Nov;27(6):856.

PMID:
27465493
27.

Rates and mechanisms of bacterial mutagenesis from maximum-depth sequencing.

Jee J, Rasouly A, Shamovsky I, Akivis Y, Steinman SR, Mishra B, Nudler E.

Nature. 2016 Jun 30;534(7609):693-6. Epub 2016 Jun 22.

28.

ppGpp couples transcription to DNA repair in E. coli.

Kamarthapu V, Epshtein V, Benjamin B, Proshkin S, Mironov A, Cashel M, Nudler E.

Science. 2016 May 20;352(6288):993-6. doi: 10.1126/science.aad6945.

29.

Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH.

Lazarev VF, Nikotina AD, Mikhaylova ER, Nudler E, Polonik SG, Guzhova IV, Margulis BA.

Biochem Biophys Res Commun. 2016 Feb 12;470(3):766-771. doi: 10.1016/j.bbrc.2015.12.076. Epub 2015 Dec 20.

PMID:
26713364
30.

Exogenous Hsp70 delays senescence and improves cognitive function in aging mice.

Bobkova NV, Evgen'ev M, Garbuz DG, Kulikov AM, Morozov A, Samokhin A, Velmeshev D, Medvinskaya N, Nesterova I, Pollock A, Nudler E.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):16006-11. doi: 10.1073/pnas.1516131112. Epub 2015 Dec 14.

31.

Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations.

Sekine S, Murayama Y, Svetlov V, Nudler E, Yokoyama S.

Transcription. 2015;6(3):56-60. doi: 10.1080/21541264.2015.1059922.

32.

The ratcheted and ratchetable structural states of RNA polymerase underlie multiple transcriptional functions.

Sekine S, Murayama Y, Svetlov V, Nudler E, Yokoyama S.

Mol Cell. 2015 Feb 5;57(3):408-21. doi: 10.1016/j.molcel.2014.12.014. Epub 2015 Jan 15.

33.

Rethinking transcription coupled DNA repair.

Kamarthapu V, Nudler E.

Curr Opin Microbiol. 2015 Apr;24:15-20. doi: 10.1016/j.mib.2014.12.005. Epub 2015 Jan 14. Review.

34.

Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase.

Mejia YX, Nudler E, Bustamante C.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):743-8. doi: 10.1073/pnas.1421067112. Epub 2014 Dec 31.

35.

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response.

Vera M, Pani B, Griffiths LA, Muchardt C, Abbott CM, Singer RH, Nudler E.

Elife. 2014 Sep 16;3:e03164. doi: 10.7554/eLife.03164.

36.

Bacterial gasotransmitters: an innate defense against antibiotics.

Luhachack L, Nudler E.

Curr Opin Microbiol. 2014 Oct;21:13-7. doi: 10.1016/j.mib.2014.06.017. Epub 2014 Jul 30. Review.

PMID:
25078319
37.

Phosphorylation of Ser8 promotes zinc-induced dimerization of the amyloid-β metal-binding domain.

Kulikova AA, Tsvetkov PO, Indeykina MI, Popov IA, Zhokhov SS, Golovin AV, Polshakov VI, Kozin SA, Nudler E, Makarov AA.

Mol Biosyst. 2014 Oct;10(10):2590-6. doi: 10.1039/c4mb00332b.

PMID:
25023775
38.

Riboswitches in regulation of Rho-dependent transcription termination.

Proshkin S, Mironov A, Nudler E.

Biochim Biophys Acta. 2014 Oct;1839(10):974-977. doi: 10.1016/j.bbagrm.2014.04.002. Epub 2014 Apr 13. Review.

PMID:
24731855
39.

UvrD facilitates DNA repair by pulling RNA polymerase backwards.

Epshtein V, Kamarthapu V, McGary K, Svetlov V, Ueberheide B, Proshkin S, Mironov A, Nudler E.

Nature. 2014 Jan 16;505(7483):372-7. doi: 10.1038/nature12928. Epub 2014 Jan 8.

40.

Therapeutic effect of exogenous hsp70 in mouse models of Alzheimer's disease.

Bobkova NV, Garbuz DG, Nesterova I, Medvinskaya N, Samokhin A, Alexandrova I, Yashin V, Karpov V, Kukharsky MS, Ninkina NN, Smirnov AA, Nudler E, Evgen'ev M.

J Alzheimers Dis. 2014;38(2):425-35. doi: 10.3233/JAD-130779.

PMID:
23985416
41.

Transcription-replication encounters, consequences and genomic instability.

Helmrich A, Ballarino M, Nudler E, Tora L.

Nat Struct Mol Biol. 2013 Apr;20(4):412-8. doi: 10.1038/nsmb.2543. Review.

PMID:
23552296
42.

RNA polymerase and the ribosome: the close relationship.

McGary K, Nudler E.

Curr Opin Microbiol. 2013 Apr;16(2):112-7. doi: 10.1016/j.mib.2013.01.010. Epub 2013 Feb 22. Review.

43.

Reactive rifampicin derivative able to damage transcription complex.

Kozlov M, Nudler E, Nikiforov V, Mustaev A.

Bioconjug Chem. 2013 Mar 20;24(3):443-7. doi: 10.1021/bc3005667. Epub 2013 Mar 1.

PMID:
23425196
44.

Bacterial nitric oxide extends the lifespan of C. elegans.

Gusarov I, Gautier L, Smolentseva O, Shamovsky I, Eremina S, Mironov A, Nudler E.

Cell. 2013 Feb 14;152(4):818-30. doi: 10.1016/j.cell.2012.12.043.

45.

Looking for a promoter in 3D.

Svetlov V, Nudler E.

Nat Struct Mol Biol. 2013 Feb;20(2):141-2. doi: 10.1038/nsmb.2498. No abstract available.

PMID:
23381630
46.

A decade of riboswitches.

Serganov A, Nudler E.

Cell. 2013 Jan 17;152(1-2):17-24. doi: 10.1016/j.cell.2012.12.024. Review.

47.

Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development.

van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V.

J Biol Chem. 2013 Mar 1;288(9):6417-26. doi: 10.1074/jbc.M112.448738. Epub 2013 Jan 15.

48.

The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.

Nedialkov YA, Opron K, Assaf F, Artsimovitch I, Kireeva ML, Kashlev M, Cukier RI, Nudler E, Burton ZF.

Biochim Biophys Acta. 2013 Feb;1829(2):187-98. doi: 10.1016/j.bbagrm.2012.11.005. Epub 2012 Nov 30.

49.

RNA polymerase stalls in a post-translocated register and can hyper-translocate.

Nedialkov YA, Nudler E, Burton ZF.

Transcription. 2012 Sep-Oct;3(5):260-9. doi: 10.4161/trns.22307. Epub 2012 Sep 1.

50.

Basic mechanism of transcription by RNA polymerase II.

Svetlov V, Nudler E.

Biochim Biophys Acta. 2013 Jan;1829(1):20-8. doi: 10.1016/j.bbagrm.2012.08.009. Epub 2012 Sep 6. Review.

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