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Items: 11

1.

Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile.

Werner S, Mesch S, Hillig RC, Ter Laak A, Klint J, Neagoe I, Laux-Biehlmann A, Dahllöf H, Bräuer N, Puetter V, Nubbemeyer R, Schulz S, Bairlein M, Zollner TM, Steinmeyer A.

J Med Chem. 2019 Dec 26;62(24):11194-11217. doi: 10.1021/acs.jmedchem.9b01304. Epub 2019 Dec 11.

PMID:
31746599
2.

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo.

Wortmann L, Lindenthal B, Muhn P, Walter A, Nubbemeyer R, Heldmann D, Sobek L, Morandi F, Schrey AK, Moosmayer D, Günther J, Kuhnke J, Koppitz M, Lücking U, Röhn U, Schäfer M, Nowak-Reppel K, Kühne R, Weinmann H, Langer G.

J Med Chem. 2019 Nov 27;62(22):10321-10341. doi: 10.1021/acs.jmedchem.9b01382. Epub 2019 Nov 13.

PMID:
31670515
3.

Estradiol release kinetics determine tissue response in ovariectomized rats.

Otto C, Kantner I, Nubbemeyer R, Schkoldow J, Fuchs I, Krahl E, Vonk R, Schüler C, Fritzemeier KH, Erben RG.

Endocrinology. 2012 Apr;153(4):1725-33. doi: 10.1210/en.2011-1801. Epub 2012 Feb 14.

PMID:
22334713
4.

G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol.

Otto C, Rohde-Schulz B, Schwarz G, Fuchs I, Klewer M, Brittain D, Langer G, Bader B, Prelle K, Nubbemeyer R, Fritzemeier KH.

Endocrinology. 2008 Oct;149(10):4846-56. doi: 10.1210/en.2008-0269. Epub 2008 Jun 19.

PMID:
18566127
5.

Efomycine M: an inhibitor of selectins?

von Bonin A, Buchmann B, Bader B, Rausch A, Venstrom K, Schäfer M, Gründemann S, Günther J, Zorn L, Nubbemeyer R, Asadullah K, Zollner TM.

Nat Med. 2006 Aug;12(8):873; author reply 873-4. No abstract available.

PMID:
16892024
6.

Targeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertility.

Davies B, Baumann C, Kirchhoff C, Ivell R, Nubbemeyer R, Habenicht UF, Theuring F, Gottwald U.

Mol Cell Biol. 2004 Oct;24(19):8642-8.

7.

Biological effects of ERalpha- and ERbeta-selective estrogens.

Fritzemeier KH, Hillisch A, Elger W, Kaufmann U, Kollenkirchen U, Kosemund D, Lindenthal B, Müller G, Muhn P, Nubbemeyer R, Peters O, Siebel P, Hegele-Hartung C.

Ernst Schering Res Found Workshop. 2004;(46):127-50. Review. No abstract available.

PMID:
15248509
8.

Progesterone and testosterone concentrations during oestrous cycle and pregnancy in the common vole (Microtus arvalis Pallas).

Nubbemeyer R.

Comp Biochem Physiol A Mol Integr Physiol. 1999 Apr;122(4):437-44.

PMID:
10422259
9.

Relaxin in the marmoset monkey: secretion pattern in the ovarian cycle and early pregnancy.

Einspanier A, Nubbemeyer R, Schlote S, Schumacher M, Ivell R, Fuhrmann K, Marten A.

Biol Reprod. 1999 Aug;61(2):512-20.

PMID:
10411534
10.

Artificial insemination in Callithrix jacchus using fresh or cryopreserved sperm.

Morrell JM, Nubbemeyer R, Heistermann M, Rosenbusch J, Küderling I, Holt W, Hodges JK.

Anim Reprod Sci. 1998 Aug 21;52(2):165-74.

PMID:
9776489
11.

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