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Items: 3


Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.

Xiong Y, Walker K, Min X, Hale C, Tran T, Komorowski R, Yang J, Davda J, Nuanmanee N, Kemp D, Wang X, Liu H, Miller S, Lee KJ, Wang Z, Véniant MM.

Sci Transl Med. 2017 Oct 18;9(412). pii: eaan8732. doi: 10.1126/scitranslmed.aan8732. Erratum in: Sci Transl Med. 2018 Aug 29;10(456):.


Recombinant human lecithin-cholesterol acyltransferase Fc fusion: analysis of N- and O-linked glycans and identification and elimination of a xylose-based O-linked tetrasaccharide core in the linker region.

Spahr C, Kim JJ, Deng S, Kodama P, Xia Z, Tang J, Zhang R, Siu S, Nuanmanee N, Estes B, Stevens J, Zhou M, Lu HS.

Protein Sci. 2013 Dec;22(12):1739-53. doi: 10.1002/pro.2373.


Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.

Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, Gupte J, Komorowski R, Sekirov L, Hager T, Arora T, Ge H, Baribault H, Wang F, Sheng J, Karow M, Wang M, Luo Y, McKeehan W, Wang Z, Véniant MM, Li Y.

Sci Transl Med. 2012 Nov 28;4(162):162ra153. doi: 10.1126/scitranslmed.3004690.

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