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Items: 1 to 50 of 161

1.

Highlighting inflammation and lipid metabolism.

Ntambi JM.

Biochem Biophys Res Commun. 2019 Dec 17;520(4):688-689. doi: 10.1016/j.bbrc.2019.10.014. No abstract available.

PMID:
31761079
2.

Hepatic stearoyl CoA desaturase 1 deficiency increases glucose uptake in adipose tissue partially through the PGC-1α-FGF21 axis in mice.

AlJohani A, Khan MI, Bonneville A, Guo C, Jeffery J, O'Neill L, Syed DN, Lewis SA, Burhans M, Mukhtar H, Ntambi JM.

J Biol Chem. 2019 Nov 5. pii: jbc.RA119.009868. doi: 10.1074/jbc.RA119.009868. [Epub ahead of print]

3.

Hepatic Stearoyl-CoA desaturase-1 deficiency-mediated activation of mTORC1- PGC-1α axis regulates ER stress during high-carbohydrate feeding.

Aljohani A, Khan MI, Syed DN, Abram B, Lewis S, Neill LO, Mukhtar H, Ntambi JM.

Sci Rep. 2019 Oct 31;9(1):15761. doi: 10.1038/s41598-019-52339-7.

4.

Role of Oleic Acid in the Gut-Liver Axis: From Diet to the Regulation of Its Synthesis via Stearoyl-CoA Desaturase 1 (SCD1).

Piccinin E, Cariello M, De Santis S, Ducheix S, Sabbà C, Ntambi JM, Moschetta A.

Nutrients. 2019 Sep 24;11(10). pii: E2283. doi: 10.3390/nu11102283. Review.

5.

Evaporative cooling provides a major metabolic energy sink.

Kasza I, Adler D, Nelson DW, Eric Yen CL, Dumas S, Ntambi JM, MacDougald OA, Hernando D, Porter WP, Best FA, Alexander CM.

Mol Metab. 2019 Sep;27:47-61. doi: 10.1016/j.molmet.2019.06.023. Epub 2019 Jul 1.

6.

PGC-1a integrates a metabolism and growth network linked to caloric restriction.

Miller KN, Clark JP, Martin SA, Howell PR, Burhans MS, Haws SA, Johnson NB, Rhoads TW, Pavelec DM, Eliceiri KW, Roopra AS, Ntambi JM, Denu JM, Parks BW, Anderson RM.

Aging Cell. 2019 Oct;18(5):e12999. doi: 10.1111/acel.12999. Epub 2019 Jul 3.

7.

SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle.

Dziewulska A, Dobosz AM, Dobrzyn A, Smolinska A, Kolczynska K, Ntambi JM, Dobrzyn P.

J Cell Physiol. 2020 Feb;235(2):1129-1140. doi: 10.1002/jcp.29026. Epub 2019 Jun 26.

PMID:
31241768
8.

A Discussion on the Relationship between Skin Lipid Metabolism and Whole-Body Glucose and Lipid Metabolism: Systematic Review.

Dumas SN, Ntambi JM.

J Cell Signal. 2018;3(3). pii: 189. doi: 10.4172/2576-1471.1000189. Epub 2018 Oct 10.

9.

Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver.

Dumas SN, Guo CA, Kim JK, Friedline RH, Ntambi JM.

Biochem Biophys Res Commun. 2019 Jan 1;508(1):87-91. doi: 10.1016/j.bbrc.2018.11.083. Epub 2018 Nov 22.

PMID:
30470572
10.

Uncoupling protein-1 deficiency promotes brown adipose tissue inflammation and ER stress.

Bond LM, Burhans MS, Ntambi JM.

PLoS One. 2018 Nov 14;13(11):e0205726. doi: 10.1371/journal.pone.0205726. eCollection 2018.

11.

Proproliferative function of adaptor protein GRB10 in prostate carcinoma.

Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S, Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H.

FASEB J. 2019 Mar;33(3):3198-3211. doi: 10.1096/fj.201800265RR. Epub 2018 Oct 31.

PMID:
30379590
12.

Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice.

Mukherjee P, Hough G, Chattopadhyay A, Grijalva V, O'Connor EI, Meriwether D, Wagner A, Ntambi JM, Navab M, Reddy ST, Fogelman AM.

J Lipid Res. 2018 Oct;59(10):1818-1840. doi: 10.1194/jlr.M083527. Epub 2018 Aug 23.

13.

Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate.

Ducheix S, Peres C, Härdfeldt J, Frau C, Mocciaro G, Piccinin E, Lobaccaro JM, De Santis S, Chieppa M, Bertrand-Michel J, Plateroti M, Griffin JL, Sabbà C, Ntambi JM, Moschetta A.

Gastroenterology. 2018 Nov;155(5):1524-1538.e9. doi: 10.1053/j.gastro.2018.07.032. Epub 2018 Jul 29.

PMID:
30063922
14.

Increased hydrophilic plasma bile acids are correlated with protection from adiposity in skin-specific stearoyl-CoA desaturase-1 deficient mice.

Dumas SN, Ntambi JM.

PLoS One. 2018 Jul 2;13(7):e0199682. doi: 10.1371/journal.pone.0199682. eCollection 2018.

15.

Lipidomic insight into cardiovascular diseases.

Kohno S, Keenan AL, Ntambi JM, Miyazaki M.

Biochem Biophys Res Commun. 2018 Oct 7;504(3):590-595. doi: 10.1016/j.bbrc.2018.04.106. Epub 2018 Apr 19. Review.

16.

Compensatory increases in tear volume and mucin levels associated with meibomian gland dysfunction caused by stearoyl-CoA desaturase-1 deficiency.

Inaba T, Tanaka Y, Tamaki S, Ito T, Ntambi JM, Tsubota K.

Sci Rep. 2018 Feb 20;8(1):3358. doi: 10.1038/s41598-018-21542-3.

17.

Co-conspirators in a new mechanism for the degradation of Δ9-desaturase.

Dumas S, Ntambi JM.

J Biol Chem. 2017 Dec 8;292(49):19987-19988. doi: 10.1074/jbc.H117.801936. Review.

18.

UCP1 deficiency increases adipose tissue monounsaturated fatty acid synthesis and trafficking to the liver.

Bond LM, Ntambi JM.

J Lipid Res. 2018 Feb;59(2):224-236. doi: 10.1194/jlr.M078469. Epub 2017 Dec 3.

19.

Insights into Stearoyl-CoA Desaturase-1 Regulation of Systemic Metabolism.

ALJohani AM, Syed DN, Ntambi JM.

Trends Endocrinol Metab. 2017 Dec;28(12):831-842. doi: 10.1016/j.tem.2017.10.003. Epub 2017 Oct 28. Review.

20.

The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction.

Forney LA, Stone KP, Wanders D, Ntambi JM, Gettys TW.

Appl Physiol Nutr Metab. 2018 Feb;43(2):123-130. doi: 10.1139/apnm-2017-0404. Epub 2017 Oct 5.

21.

Oleate activates SREBP-1 signaling activity in SCD1-deficient hepatocytes.

Lounis MA, Bergeron KF, Burhans MS, Ntambi JM, Mounier C.

Am J Physiol Endocrinol Metab. 2017 Dec 1;313(6):E710-E720. doi: 10.1152/ajpendo.00151.2017. Epub 2017 Aug 29.

22.

Physical Activity, Sleep, and BMI Percentile in Rural and Urban Ugandan Youth.

Christoph MJ, Grigsby-Toussaint DS, Baingana R, Ntambi JM.

Ann Glob Health. 2017 Mar - Apr;83(2):311-319. doi: 10.1016/j.aogh.2017.04.005. Epub 2017 May 29.

23.

Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion.

Ansari IH, Longacre MJ, Stoker SW, Kendrick MA, O'Neill LM, Zitur LJ, Fernandez LA, Ntambi JM, MacDonald MJ.

Arch Biochem Biophys. 2017 Mar 15;618:32-43. doi: 10.1016/j.abb.2017.02.001. Epub 2017 Feb 11.

24.

Aging and caloric restriction impact adipose tissue, adiponectin, and circulating lipids.

Miller KN, Burhans MS, Clark JP, Howell PR, Polewski MA, DeMuth TM, Eliceiri KW, Lindstrom MJ, Ntambi JM, Anderson RM.

Aging Cell. 2017 Jun;16(3):497-507. doi: 10.1111/acel.12575. Epub 2017 Feb 3.

25.

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.

Lai KKY, Kweon SM, Chi F, Hwang E, Kabe Y, Higashiyama R, Qin L, Yan R, Wu RP, Lai K, Fujii N, French S, Xu J, Wang JY, Murali R, Mishra L, Lee JS, Ntambi JM, Tsukamoto H.

Gastroenterology. 2017 May;152(6):1477-1491. doi: 10.1053/j.gastro.2017.01.021. Epub 2017 Jan 29.

26.

Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor α.

Bednarski T, Olichwier A, Opasinska A, Pyrkowska A, Gan AM, Ntambi JM, Dobrzyn P.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):2029-2037. doi: 10.1016/j.bbalip.2016.10.005. Epub 2016 Oct 15.

PMID:
27751891
27.

Differential Effects of Dietary Fat Content and Protein Source on Bone Phenotype and Fatty Acid Oxidation in Female C57Bl/6 Mice.

Sawin EA, Stroup BM, Murali SG, O'Neill LM, Ntambi JM, Ney DM.

PLoS One. 2016 Oct 3;11(10):e0163234. doi: 10.1371/journal.pone.0163234. eCollection 2016.

28.

SCD1 deficiency protects mice against ethanol-induced liver injury.

Lounis MA, Escoula Q, Veillette C, Bergeron KF, Ntambi JM, Mounier C.

Biochim Biophys Acta. 2016 Nov;1861(11):1662-1670. doi: 10.1016/j.bbalip.2016.07.012. Epub 2016 Jul 28.

PMID:
27477676
29.

miRNAs Caught Up in Metabolic Organ Crosstalk to Combat Obesity.

Ntambi JM.

EBioMedicine. 2016 Mar 8;5:10-1. doi: 10.1016/j.ebiom.2016.03.007. eCollection 2016 Mar. No abstract available.

30.

Hepatic oleate regulates liver stress response partially through PGC-1α during high-carbohydrate feeding.

Liu X, Burhans MS, Flowers MT, Ntambi JM.

J Hepatol. 2016 Jul;65(1):103-112. doi: 10.1016/j.jhep.2016.03.001. Epub 2016 Mar 11.

31.

Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.

Singh V, Chassaing B, Zhang L, San Yeoh B, Xiao X, Kumar M, Baker MT, Cai J, Walker R, Borkowski K, Harvatine KJ, Singh N, Shearer GC, Ntambi JM, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M.

Cell Metab. 2015 Dec 1;22(6):983-96. doi: 10.1016/j.cmet.2015.09.028. Epub 2015 Oct 29.

32.

Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity.

Masuda M, Miyazaki-Anzai S, Keenan AL, Okamura K, Kendrick J, Chonchol M, Offermanns S, Ntambi JM, Kuro-O M, Miyazaki M.

J Clin Invest. 2015 Oct 26;125(12):4544-58. doi: 10.1172/JCI82871.

33.

Fungal Morphology, Iron Homeostasis, and Lipid Metabolism Regulated by a GATA Transcription Factor in Blastomyces dermatitidis.

Marty AJ, Broman AT, Zarnowski R, Dwyer TG, Bond LM, Lounes-Hadj Sahraoui A, Fontaine J, Ntambi JM, Keleş S, Kendziorski C, Gauthier GM.

PLoS Pathog. 2015 Jun 26;11(6):e1004959. doi: 10.1371/journal.ppat.1004959. eCollection 2015 Jun.

34.

Plasma diacylglycerol composition is a biomarker of metabolic syndrome onset in rhesus monkeys.

Polewski MA, Burhans MS, Zhao M, Colman RJ, Shanmuganayagam D, Lindstrom MJ, Ntambi JM, Anderson RM.

J Lipid Res. 2015 Aug;56(8):1461-70. doi: 10.1194/jlr.M057562. Epub 2015 Jun 10.

35.

Characterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation.

MacDonald MJ, Ade L, Ntambi JM, Ansari IU, Stoker SW.

J Biol Chem. 2015 Apr 24;290(17):11075-92. doi: 10.1074/jbc.M114.628420. Epub 2015 Mar 11.

36.

Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation.

Burhans MS, Flowers MT, Harrington KR, Bond LM, Guo CA, Anderson RM, Ntambi JM.

J Lipid Res. 2015 Feb;56(2):304-18. doi: 10.1194/jlr.M054429. Epub 2015 Jan 2.

37.

Novel entries in a fungal biofilm matrix encyclopedia.

Zarnowski R, Westler WM, Lacmbouh GA, Marita JM, Bothe JR, Bernhardt J, Lounes-Hadj Sahraoui A, Fontaine J, Sanchez H, Hatfield RD, Ntambi JM, Nett JE, Mitchell AP, Andes DR.

MBio. 2014 Aug 5;5(4):e01333-14. doi: 10.1128/mBio.01333-14.

38.

Global deletion of lipocalin 2 does not reverse high-fat diet-induced obesity resistance in stearoyl-CoA desaturase-1 skin-specific knockout mice.

Friedlander NJ, Burhans MS, Ade L, O'Neill LM, Chen X, Ntambi JM.

Biochem Biophys Res Commun. 2014 Mar 14;445(3):578-83. doi: 10.1016/j.bbrc.2014.02.035. Epub 2014 Feb 15.

39.

Role of stearoyl-CoA desaturase-1 in skin integrity and whole body energy balance.

Sampath H, Ntambi JM.

J Biol Chem. 2014 Jan 31;289(5):2482-8. doi: 10.1074/jbc.R113.516716. Epub 2013 Dec 19. Review.

40.

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase.

Liu J, Cinar R, Xiong K, Godlewski G, Jourdan T, Lin Y, Ntambi JM, Kunos G.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18832-7. doi: 10.1073/pnas.1309469110. Epub 2013 Nov 4.

41.

SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice.

Rogowski MP, Flowers MT, Stamatikos AD, Ntambi JM, Paton CM.

J Lipid Res. 2013 Oct;54(10):2636-46. doi: 10.1194/jlr.M035865. Epub 2013 Aug 5.

42.

Knockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cells.

MacDonald MJ, Hasan NM, Dobrzyn A, Stoker SW, Ntambi JM, Liu X, Sampath H.

Arch Biochem Biophys. 2013 Apr 1;532(1):23-31. doi: 10.1016/j.abb.2013.01.002. Epub 2013 Jan 25.

43.

Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle.

Dziewulska A, Dobrzyn P, Jazurek M, Pyrkowska A, Ntambi JM, Dobrzyn A.

Mol Membr Biol. 2012 Nov;29(7):309-20. doi: 10.3109/09687688.2012.710340. Epub 2012 Aug 13.

PMID:
22881371
44.

Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity.

Flowers MT, Ade L, Strable MS, Ntambi JM.

J Lipid Res. 2012 Aug;53(8):1646-53. doi: 10.1194/jlr.M027508. Epub 2012 Jun 5.

45.

Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis.

Scott KE, Wheeler FB, Davis AL, Thomas MJ, Ntambi JM, Seals DF, Kridel SJ.

PLoS One. 2012;7(1):e29761. doi: 10.1371/journal.pone.0029761. Epub 2012 Jan 6.

46.

The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation.

Sampath H, Ntambi JM.

Ann N Y Acad Sci. 2011 Dec;1243:47-53. doi: 10.1111/j.1749-6632.2011.06303.x. Review.

PMID:
22211892
47.

Stearoyl CoA desaturase 1: role in cellular inflammation and stress.

Liu X, Strable MS, Ntambi JM.

Adv Nutr. 2011 Jan;2(1):15-22. doi: 10.3945/an.110.000125. Epub 2011 Jan 10. Review.

48.

Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro.

Kim E, Lee JH, Ntambi JM, Hyun CK.

Eur J Pharmacol. 2011 Dec 15;672(1-3):38-44. doi: 10.1016/j.ejphar.2011.09.172. Epub 2011 Sep 29.

PMID:
21970804
49.

Basic science research and education: a priority for training and capacity building in developing countries.

Deckelbaum RJ, Ntambi JM, Wolgemuth DJ.

Infect Dis Clin North Am. 2011 Sep;25(3):669-76, x. doi: 10.1016/j.idc.2011.05.009.

PMID:
21896366
50.

The role of fatty acid desaturases in epidermal metabolism.

Sampath H, Ntambi JM.

Dermatoendocrinol. 2011 Apr;3(2):62-4. doi: 10.4161/derm.3.2.14832. Epub 2011 Apr 1.

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