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Items: 32

1.

Plasmodium Species Infecting Children Presenting with Malaria in Uganda.

Asua V, Tukwasibwe S, Conrad M, Walakira A, Nankabirwa JI, Mugenyi L, Kamya MR, Nsobya SL, Rosenthal PJ.

Am J Trop Med Hyg. 2017 Sep;97(3):753-757. doi: 10.4269/ajtmh.17-0345.

PMID:
28990911
2.

Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda.

Walakira A, Tukwasibwe S, Kiggundu M, Verra F, Kakeeto P, Ruhamyankaka E, Drakeley C, Dorsey G, Kamya MR, Nsobya SL, Rosenthal PJ.

Infect Genet Evol. 2017 Nov;55:281-287. doi: 10.1016/j.meegid.2017.09.021. Epub 2017 Sep 19.

PMID:
28939159
3.

Changing Antimalarial Drug Sensitivities in Uganda.

Rasmussen SA, Ceja FG, Conrad MD, Tumwebaze PK, Byaruhanga O, Katairo T, Nsobya SL, Rosenthal PJ, Cooper RA.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01516-17. doi: 10.1128/AAC.01516-17. Print 2017 Dec.

4.

Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda.

Tukwasibwe S, Tumwebaze P, Conrad M, Arinaitwe E, Kamya MR, Dorsey G, Nsobya SL, Greenhouse B, Rosenthal PJ.

Malar J. 2017 Mar 21;16(1):125. doi: 10.1186/s12936-017-1777-0.

5.

Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda.

Tumwebaze P, Tukwasibwe S, Taylor A, Conrad M, Ruhamyankaka E, Asua V, Walakira A, Nankabirwa J, Yeka A, Staedke SG, Greenhouse B, Nsobya SL, Kamya MR, Dorsey G, Rosenthal PJ.

J Infect Dis. 2017 Feb 15;215(4):631-635. doi: 10.1093/infdis/jiw614.

6.

Performance of Kalon herpes simplex virus 2 assay using dried blood spots among young women in Uganda.

Nsobya SL, Hewett PC, Kalibala S, Mensch BS.

Afr J Lab Med. 2016;5(1). pii: 429. doi: 10.4102/ajlm.v5i1.429. Epub 2016 Aug 16.

7.

Molecular surveillance of Plasmodium falciparum drug resistance markers reveals partial recovery of chloroquine susceptibility but sustained sulfadoxine-pyrimethamine resistance at two sites of different malaria transmission intensities in Rwanda.

Kateera F, Nsobya SL, Tukwasibwe S, Hakizimana E, Mutesa L, Mens PF, Grobusch MP, van Vugt M, Kumar N.

Acta Trop. 2016 Dec;164:329-336. doi: 10.1016/j.actatropica.2016.09.008. Epub 2016 Sep 17.

PMID:
27647575
8.

Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity.

Nankabirwa JI, Conrad MD, Legac J, Tukwasibwe S, Tumwebaze P, Wandera B, Brooker SJ, Staedke SG, Kamya MR, Nsobya SL, Dorsey G, Rosenthal PJ.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5649-54. doi: 10.1128/AAC.00920-16. Print 2016 Oct.

9.

Malaria case clinical profiles and Plasmodium falciparum parasite genetic diversity: a cross sectional survey at two sites of different malaria transmission intensities in Rwanda.

Kateera F, Nsobya SL, Tukwasibwe S, Mens PF, Hakizimana E, Grobusch MP, Mutesa L, Kumar N, van Vugt M.

Malar J. 2016 Apr 26;15:237. doi: 10.1186/s12936-016-1287-5.

10.

Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays.

Cooper RA, Conrad MD, Watson QD, Huezo SJ, Ninsiima H, Tumwebaze P, Nsobya SL, Rosenthal PJ.

Antimicrob Agents Chemother. 2015 Aug;59(8):5061-4. doi: 10.1128/AAC.00921-15. Epub 2015 Jun 1.

11.

Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.

Tumwebaze P, Conrad MD, Walakira A, LeClair N, Byaruhanga O, Nakazibwe C, Kozak B, Bloome J, Okiring J, Kakuru A, Bigira V, Kapisi J, Legac J, Gut J, Cooper RA, Kamya MR, Havlir DV, Dorsey G, Greenhouse B, Nsobya SL, Rosenthal PJ.

Antimicrob Agents Chemother. 2015;59(6):3018-30. doi: 10.1128/AAC.05141-14. Epub 2015 Mar 9.

12.

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers.

Perry GH, Foll M, Grenier JC, Patin E, Nédélec Y, Pacis A, Barakatt M, Gravel S, Zhou X, Nsobya SL, Excoffier L, Quintana-Murci L, Dominy NJ, Barreiro LB.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3596-603. doi: 10.1073/pnas.1402875111. Epub 2014 Aug 18.

13.

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.

Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, Mårtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TM, Ménard D, Adam I, Ademowo G, Arze C, Baliraine FN, Berens-Riha N, Björkman A, Borrmann S, Checchi F, Desai M, Dhorda M, Djimdé AA, El-Sayed BB, Eshetu T, Eyase F, Falade C, Faucher JF, Fröberg G, Grivoyannis A, Hamour S, Houzé S, Johnson J, Kamugisha E, Kariuki S, Kiechel JR, Kironde F, Kofoed PE, LeBras J, Malmberg M, Mwai L, Ngasala B, Nosten F, Nsobya SL, Nzila A, Oguike M, Otienoburu SD, Ogutu B, Ouédraogo JB, Piola P, Rombo L, Schramm B, Somé AF, Thwing J, Ursing J, Wong RP, Zeynudin A, Zongo I, Plowe CV, Sibley CH; ASAQ Molecular Marker Study Group; WWARN AL.

Am J Trop Med Hyg. 2014 Oct;91(4):833-43. doi: 10.4269/ajtmh.14-0031. Epub 2014 Jul 21. Erratum in: Am J Trop Med Hyg. 2015 May;92(5):1084.

14.

Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda.

Mbogo GW, Nankoberanyi S, Tukwasibwe S, Baliraine FN, Nsobya SL, Conrad MD, Arinaitwe E, Kamya M, Tappero J, Staedke SG, Dorsey G, Greenhouse B, Rosenthal PJ.

Am J Trop Med Hyg. 2014 Jul;91(1):54-61. doi: 10.4269/ajtmh.13-0647. Epub 2014 May 5.

15.

Estimation of malaria haplotype and genotype frequencies: a statistical approach to overcome the challenge associated with multiclonal infections.

Taylor AR, Flegg JA, Nsobya SL, Yeka A, Kamya MR, Rosenthal PJ, Dorsey G, Sibley CH, Guerin PJ, Holmes CC.

Malar J. 2014 Mar 17;13:102. doi: 10.1186/1475-2875-13-102.

16.

Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda.

Nankoberanyi S, Mbogo GW, LeClair NP, Conrad MD, Tumwebaze P, Tukwasibwe S, Kamya MR, Tappero J, Nsobya SL, Rosenthal PJ.

Malar J. 2014 Mar 14;13:95. doi: 10.1186/1475-2875-13-95.

17.

Using biomarkers to assess the validity of sexual behavior reporting across interview modes among young women in Kampala, Uganda.

Kelly CA, Hewett PC, Mensch BS, Rankin JC, Nsobya SL, Kalibala S, Kakande PN.

Stud Fam Plann. 2014 Mar;45(1):43-58. doi: 10.1111/j.1728-4465.2014.00375.x.

18.

Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic falciparum malaria infections in Uganda.

Tukwasibwe S, Mugenyi L, Mbogo GW, Nankoberanyi S, Maiteki-Sebuguzi C, Joloba ML, Nsobya SL, Staedke SG, Rosenthal PJ.

J Infect Dis. 2014 Jul 1;210(1):154-7. Epub 2014 Jan 19.

19.

Optimization of a ligase detection reaction-fluorescent microsphere assay for characterization of resistance-mediating polymorphisms in African samples of Plasmodium falciparum.

LeClair NP, Conrad MD, Baliraine FN, Nsanzabana C, Nsobya SL, Rosenthal PJ.

J Clin Microbiol. 2013 Aug;51(8):2564-70. doi: 10.1128/JCM.00904-13. Epub 2013 May 29.

20.

High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.

Woodrow CJ, Dahlström S, Cooksey R, Flegg JA, Le Nagard H, Mentré F, Murillo C, Ménard D, Nosten F, Sriprawat K, Musset L, Quashie NB, Lim P, Fairhurst RM, Nsobya SL, Sinou V, Noedl H, Pradines B, Johnson JD, Guerin PJ, Sibley CH, Le Bras J.

Antimicrob Agents Chemother. 2013 Jul;57(7):3121-30. doi: 10.1128/AAC.02350-12. Epub 2013 Apr 22.

21.

Evaluation of a comprehensive refresher training program in malaria microscopy covering four districts of Uganda.

Kiggundu M, Nsobya SL, Kamya MR, Filler S, Nasr S, Dorsey G, Yeka A.

Am J Trop Med Hyg. 2011 May;84(5):820-4. doi: 10.4269/ajtmh.2011.10-0597.

22.

Limited ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 polymorphisms to predict quinine in vitro sensitivity or clinical effectiveness in Uganda.

Baliraine FN, Nsobya SL, Achan J, Tibenderana JK, Talisuna AO, Greenhouse B, Rosenthal PJ.

Antimicrob Agents Chemother. 2011 Feb;55(2):615-22. doi: 10.1128/AAC.00954-10. Epub 2010 Nov 15.

23.

In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.

Nsobya SL, Kiggundu M, Nanyunja S, Joloba M, Greenhouse B, Rosenthal PJ.

Antimicrob Agents Chemother. 2010 Mar;54(3):1200-6. doi: 10.1128/AAC.01412-09. Epub 2010 Jan 11.

24.

Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda.

Nawaz F, Nsobya SL, Kiggundu M, Joloba M, Rosenthal PJ.

J Infect Dis. 2009 Dec 1;200(11):1650-7. doi: 10.1086/647988.

25.

Complexity of Plasmodium falciparum clinical samples from Uganda during short-term culture.

Nsobya SL, Kiggundu M, Joloba M, Dorsey G, Rosenthal PJ.

J Infect Dis. 2008 Nov 15;198(10):1554-7. doi: 10.1086/592506.

PMID:
18808336
26.

Resistance-mediating Plasmodium falciparum pfcrt and pfmdr1 alleles after treatment with artesunate-amodiaquine in Uganda.

Nsobya SL, Dokomajilar C, Joloba M, Dorsey G, Rosenthal PJ.

Antimicrob Agents Chemother. 2007 Aug;51(8):3023-5. Epub 2007 Jun 11.

27.

Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic.

Dokomajilar C, Nsobya SL, Greenhouse B, Rosenthal PJ, Dorsey G.

Antimicrob Agents Chemother. 2006 May;50(5):1893-5.

28.

Complexity of Plasmodium falciparum infections and antimalarial drug efficacy at 7 sites in Uganda.

Lee SA, Yeka A, Nsobya SL, Dokomajilar C, Rosenthal PJ, Talisuna A, Dorsey G.

J Infect Dis. 2006 Apr 15;193(8):1160-3. Epub 2006 Mar 13.

PMID:
16544257
29.

Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance.

Francis D, Nsobya SL, Talisuna A, Yeka A, Kamya MR, Machekano R, Dokomajilar C, Rosenthal PJ, Dorsey G.

J Infect Dis. 2006 Apr 1;193(7):978-86. Epub 2006 Mar 1.

PMID:
16518760
30.

Effect of HIV-1 infection on antimalarial treatment outcomes in Uganda: a population-based study.

Kamya MR, Gasasira AF, Yeka A, Bakyaita N, Nsobya SL, Francis D, Rosenthal PJ, Dorsey G, Havlir D.

J Infect Dis. 2006 Jan 1;193(1):9-15. Epub 2005 Nov 18.

PMID:
16323126
31.

Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda.

Yeka A, Banek K, Bakyaita N, Staedke SG, Kamya MR, Talisuna A, Kironde F, Nsobya SL, Kilian A, Slater M, Reingold A, Rosenthal PJ, Wabwire-Mangen F, Dorsey G.

PLoS Med. 2005 Jul;2(7):e190. Epub 2005 Jul 26.

32.

Molecular evaluation of the natural history of asymptomatic parasitemia in Ugandan children.

Nsobya SL, Parikh S, Kironde F, Lubega G, Kamya MR, Rosenthal PJ, Dorsey G.

J Infect Dis. 2004 Jun 15;189(12):2220-6. Epub 2004 May 24.

PMID:
15181569

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