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Items: 1 to 50 of 113

1.

Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis.

Shen H, Yang N, Truskinovsky A, Chen Y, Mussell AL, Nowak NJ, Kobzik L, Frangou C, Zhang J.

Mol Cancer Res. 2019 Jan;17(1):250-262. doi: 10.1158/1541-7786.MCR-18-0332. Epub 2018 Sep 20.

PMID:
30237296
2.

Computational approach for deriving cancer progression roadmaps from static sample data.

Sun Y, Yao J, Yang L, Chen R, Nowak NJ, Goodison S.

Nucleic Acids Res. 2017 May 19;45(9):e69. doi: 10.1093/nar/gkx003.

3.

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets.

Frangou C, Li YW, Shen H, Yang N, Wilson KE, Blijlevens M, Guo J, Nowak NJ, Zhang J.

Oncotarget. 2014 Dec 15;5(23):12166-76.

4.

Cancer progression modeling using static sample data.

Sun Y, Yao J, Nowak NJ, Goodison S.

Genome Biol. 2014 Aug 26;15(8):440. doi: 10.1186/s13059-014-0440-0.

5.

Alterations in chromatin accessibility and DNA methylation in clear cell renal cell carcinoma.

Buck MJ, Raaijmakers LM, Ramakrishnan S, Wang D, Valiyaparambil S, Liu S, Nowak NJ, Pili R.

Oncogene. 2014 Oct 9;33(41):4961-5. doi: 10.1038/onc.2013.455. Epub 2013 Nov 4.

PMID:
24186201
6.

FOXO1 regulates expression of a microRNA cluster on X chromosome.

Singhal R, Bard JE, Nowak NJ, Buck MJ, Kandel ES.

Aging (Albany NY). 2013 May;5(5):347-56.

7.

Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast.

Liao S, Desouki MM, Gaile DP, Shepherd L, Nowak NJ, Conroy J, Barry WT, Geradts J.

Genes Chromosomes Cancer. 2012 Dec;51(12):1067-78. doi: 10.1002/gcc.21991. Epub 2012 Aug 9.

8.

Development and characterization of a novel human Waldenström macroglobulinemia cell line: RPCI-WM1, Roswell Park Cancer Institute - Waldenström Macroglobulinemia 1.

Chitta KS, Paulus A, Ailawadhi S, Foster BA, Moser MT, Starostik P, Masood A, Sher T, Miller KC, Iancu DM, Conroy J, Nowak NJ, Sait SN, Personett DA, Coleman M, Furman RR, Martin P, Ansell SM, Lee K, Chanan-Khan AA.

Leuk Lymphoma. 2013 Feb;54(2):387-96. doi: 10.3109/10428194.2012.713481. Epub 2012 Aug 27.

9.

Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation.

Yao S, Sucheston LE, Smiley SL, Davis W, Conroy JM, Nowak NJ, Ambrosone CB, McCarthy PL Jr, Hahn T.

PLoS One. 2011;6(10):e25940. doi: 10.1371/journal.pone.0025940. Epub 2011 Oct 14.

10.

Upregulation of hemoglobin expression by oxidative stress in hepatocytes and its implication in nonalcoholic steatohepatitis.

Liu W, Baker SS, Baker RD, Nowak NJ, Zhu L.

PLoS One. 2011;6(9):e24363. doi: 10.1371/journal.pone.0024363. Epub 2011 Sep 12.

11.

The genomic relationship between primary breast carcinomas and their nodal metastases.

Desouki MM, Liao S, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J.

Cancer Invest. 2011 May;29(4):300-7. doi: 10.3109/07357907.2011.568564.

PMID:
21469979
12.

Phase 1 study of arsenic trioxide, high-dose cytarabine, and idarubicin to down-regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemia.

Wetzler M, Andrews C, Ford LA, Tighe S, Barcos M, Sait SN, Block AW, Nowak NJ, Baer MR, Wang ES, Baumann H.

Cancer. 2011 Nov 1;117(21):4861-8. doi: 10.1002/cncr.26097. Epub 2011 Mar 31.

13.

Genetic analysis of Down syndrome-associated heart defects in mice.

Liu C, Morishima M, Yu T, Matsui S, Zhang L, Fu D, Pao A, Costa AC, Gardiner KJ, Cowell JK, Nowak NJ, Parmacek MS, Liang P, Baldini A, Yu YE.

Hum Genet. 2011 Nov;130(5):623-32. doi: 10.1007/s00439-011-0980-2. Epub 2011 Mar 26. Erratum in: Hum Genet. 2011 Nov;130(5):633. Nowak, Normal J [corrected to Nowak, Norma J].

14.

Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma.

Slovak ML, Bedell V, Hsu YH, Estrine DB, Nowak NJ, Delioukina ML, Weiss LM, Smith DD, Forman SJ.

Clin Cancer Res. 2011 May 15;17(10):3443-54. doi: 10.1158/1078-0432.CCR-10-1071. Epub 2011 Mar 8.

15.

Lipid in the livers of adolescents with nonalcoholic steatohepatitis: combined effects of pathways on steatosis.

Zhu L, Baker SS, Liu W, Tao MH, Patel R, Nowak NJ, Baker RD.

Metabolism. 2011 Jul;60(7):1001-11. doi: 10.1016/j.metabol.2010.10.003. Epub 2010 Nov 13.

PMID:
21075404
16.

Genomic, immunophenotypic, and NPM1/FLT3 mutational studies on 17 patients with normal karyotype acute myeloid leukemia (AML) followed by aberrant karyotype AML at relapse.

Wang ES, Sait SN, Gold D, Mashtare T, Starostik P, Ford LA, Wetzler M, Nowak NJ, Deeb G.

Cancer Genet Cytogenet. 2010 Oct 15;202(2):101-7. doi: 10.1016/j.cancergencyto.2010.07.117.

PMID:
20875872
17.

Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach.

Desouki MM, Liao S, Huang H, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J.

J Cancer Res Clin Oncol. 2011 May;137(5):795-809. doi: 10.1007/s00432-010-0937-1. Epub 2010 Aug 3.

PMID:
20680643
18.

A GOG 210 aCGH study of gain at 1q23 in endometrioid endometrial cancer in the context of racial disparity and outcome.

Morrison C, Miecznikowski J, Darcy KM, Dolce JM, Kandel E, Erwin DO, Liu S, Shepherd L, Cohn D, McMeekin DS, Block AW, Nowak NJ, Maxwell L.

Genes Chromosomes Cancer. 2010 Sep;49(9):791-802. doi: 10.1002/gcc.20782.

PMID:
20607851
19.

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.

Yu T, Li Z, Jia Z, Clapcote SJ, Liu C, Li S, Asrar S, Pao A, Chen R, Fan N, Carattini-Rivera S, Bechard AR, Spring S, Henkelman RM, Stoica G, Matsui S, Nowak NJ, Roder JC, Chen C, Bradley A, Yu YE.

Hum Mol Genet. 2010 Jul 15;19(14):2780-91. doi: 10.1093/hmg/ddq179. Epub 2010 May 4.

20.

Recurrent deletion of 9q34 in adult normal karyotype precursor B-cell acute lymphoblastic leukemia.

Nowak NJ, Sait SN, Zeidan A, Deeb G, Gaile D, Liu S, Ford L, Wallace PK, Wang ES, Wetzler M.

Cancer Genet Cytogenet. 2010 May;199(1):15-20. doi: 10.1016/j.cancergencyto.2010.01.014.

21.

Role of alcohol metabolism in non-alcoholic steatohepatitis.

Baker SS, Baker RD, Liu W, Nowak NJ, Zhu L.

PLoS One. 2010 Mar 8;5(3):e9570. doi: 10.1371/journal.pone.0009570.

22.

Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesis.

Nemajerova A, Palacios G, Nowak NJ, Matsui S, Petrenko O.

PLoS One. 2009 Nov 11;4(11):e7784. doi: 10.1371/journal.pone.0007784.

23.

Microcephaly, sensorineural deafness and Currarino triad with duplication-deletion of distal 7q.

Pavone P, Ruggieri M, Lombardo I, Sudi J, Biancheri R, Castellano-Chiodo D, Rossi A, Incorpora G, Nowak NJ, Christian SL, Pavone L, Dobyns WB.

Eur J Pediatr. 2010 Apr;169(4):475-81. doi: 10.1007/s00431-009-1061-6. Epub 2009 Oct 17.

24.

Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations.

Bruce HA, Sachs N, Rudnicki DD, Lin SG, Willour VL, Cowell JK, Conroy J, McQuaid DE, Rossi M, Gaile DP, Nowak NJ, Holmes SE, Sklar P, Ross CA, Delisi LE, Margolis RL.

Psychiatr Genet. 2009 Apr;19(2):64-71. doi: 10.1097/YPG.0b013e3283207ff6.

25.

A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism.

Kumar RA, Sudi J, Babatz TD, Brune CW, Oswald D, Yen M, Nowak NJ, Cook EH, Christian SL, Dobyns WB.

J Med Genet. 2010 Feb;47(2):81-90. doi: 10.1136/jmg.2008.065821. Epub 2009 Jun 21.

26.

Gab2-mediated signaling promotes melanoma metastasis.

Horst B, Gruvberger-Saal SK, Hopkins BD, Bordone L, Yang Y, Chernoff KA, Uzoma I, Schwipper V, Liebau J, Nowak NJ, Brunner G, Owens D, Rimm DL, Parsons R, Celebi JT.

Am J Pathol. 2009 Apr;174(4):1524-33. doi: 10.2353/ajpath.2009.080543.

27.

Uniparentalism in sporadic colorectal cancer is independent of imprint status, and coordinate for chromosomes 14 and 18.

Darbary HK, Dutt SS, Sait SJ, Nowak NJ, Heinaman RE, Stoler DL, Anderson GR.

Cancer Genet Cytogenet. 2009 Mar;189(2):77-86. doi: 10.1016/j.cancergencyto.2008.10.011.

28.

Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical region.

Ronan A, Fagan K, Christie L, Conroy J, Nowak NJ, Turner G.

BMJ Case Rep. 2009;2009. pii: bcr05.2009.1914. doi: 10.1136/bcr.05.2009.1914. Epub 2009 Jun 4.

29.

Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay.

Xiang B, Li A, Valentin D, Nowak NJ, Zhao H, Li P.

Am J Med Genet A. 2008 Aug 1;146A(15):1942-54. doi: 10.1002/ajmg.a.32411.

PMID:
18627053
30.

The BAC resource: tools for array CGH and FISH.

Nowak NJ, Snijders AM, Conroy JM, Albertson DG.

Curr Protoc Hum Genet. 2005 Aug;Chapter 4:Unit 4.13. doi: 10.1002/0471142905.hg0413s46.

PMID:
18428377
31.

Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarrays.

Yi Y, Nowak NJ, Pacchia AL, Morrison C.

Genes Chromosomes Cancer. 2008 Aug;47(8):639-48. doi: 10.1002/gcc.20565.

PMID:
18398822
32.

Novel submicroscopic chromosomal abnormalities detected in autism spectrum disorder.

Christian SL, Brune CW, Sudi J, Kumar RA, Liu S, Karamohamed S, Badner JA, Matsui S, Conroy J, McQuaid D, Gergel J, Hatchwell E, Gilliam TC, Gershon ES, Nowak NJ, Dobyns WB, Cook EH Jr.

Biol Psychiatry. 2008 Jun 15;63(12):1111-7. doi: 10.1016/j.biopsych.2008.01.009. Epub 2008 Mar 28.

33.

Recurrent 16p11.2 microdeletions in autism.

Kumar RA, KaraMohamed S, Sudi J, Conrad DF, Brune C, Badner JA, Gilliam TC, Nowak NJ, Cook EH Jr, Dobyns WB, Christian SL.

Hum Mol Genet. 2008 Feb 15;17(4):628-38. Epub 2007 Dec 21.

PMID:
18156158
34.

Estimating the arm-wise false discovery rate in array comparative genomic hybridization experiments.

Gaile DP, Schifano ED, Miecznikowski JC, Java JJ, Conroy JM, Nowak NJ.

Stat Appl Genet Mol Biol. 2007;6:Article32. Epub 2007 Nov 19.

PMID:
18052915
35.

Challenges in array comparative genomic hybridization for the analysis of cancer samples.

Nowak NJ, Miecznikowski J, Moore SR, Gaile D, Bobadilla D, Smith DD, Kernstine K, Forman SJ, Mhawech-Fauceglia P, Reid M, Stoler D, Loree T, Rigual N, Sullivan M, Weiss LM, Hicks D, Slovak ML.

Genet Med. 2007 Sep;9(9):585-95.

PMID:
17873646
36.

Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia.

Sait SN, Claydon MA, Conroy JM, Nowak NJ, Barcos M, Baer MR.

Cancer Genet Cytogenet. 2007 Sep;177(2):143-6.

PMID:
17854671
37.

Comparative genomic instabilities of thyroid and colon cancers.

Stoler DL, Nowak NJ, Matsui S, Wiseman SM, Chen N, Dutt SS, Bartos JD, Loree TR, Rigual NR, Hicks WL Jr, Sait SN, Anderson GR.

Arch Otolaryngol Head Neck Surg. 2007 May;133(5):457-63.

PMID:
17515504
38.

Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarrays.

Auer H, Newsom DL, Nowak NJ, McHugh KM, Singh S, Yu CY, Yang Y, Wenger GD, Gastier-Foster JM, Kornacker K.

BMC Genomics. 2007 Apr 30;8:111.

39.

Smith-Magenis syndrome and Moyamoya disease in a patient with del(17)(p11.2p13.1).

Girirajan S, Mendoza-Londono R, Vlangos CN, Dupuis L, Nowak NJ, Bunyan DJ, Hatchwell E, Elsea SH.

Am J Med Genet A. 2007 May 1;143A(9):999-1008.

PMID:
17431895
40.

aCGHViewer: a generic visualization tool for aCGH data.

Shankar G, Rossi MR, McQuaid DE, Conroy JM, Gaile DG, Cowell JK, Nowak NJ, Liang P.

Cancer Inform. 2006;2:36-43.

41.

Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol.

Chung I, Karpf AR, Muindi JR, Conroy JM, Nowak NJ, Johnson CS, Trump DL.

J Biol Chem. 2007 Mar 23;282(12):8704-14. Epub 2007 Jan 22.

42.

Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical region.

Ronan A, Fagan K, Christie L, Conroy J, Nowak NJ, Turner G.

J Med Genet. 2007 Jul;44(7):448-51. Epub 2007 Jan 19.

43.

aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including BCR and ABL.

Bartos JD, Gaile DP, McQuaid DE, Conroy JM, Darbary H, Nowak NJ, Block A, Petrelli NJ, Mittelman A, Stoler DL, Anderson GR.

Mutat Res. 2007 Feb 3;615(1-2):1-11. Epub 2007 Jan 2.

44.

20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcome.

Smith LT, Mayerson J, Nowak NJ, Suster D, Mohammed N, Long S, Auer H, Jones S, McKeegan C, Young G, Bos G, Plass C, Morrison C.

Genes Chromosomes Cancer. 2006 Oct;45(10):957-66.

PMID:
16847944
45.

Genomic profiles of colorectal cancers differ based on patient smoking status.

Swede H, Bartos JD, Chen N, Shaukat A, Dutt SS, McQuaid DA, Natarajan N, Rodriguez-Bigas MA, Nowak NJ, Wiseman SM, Alrawi S, Brenner BM, Petrelli NJ, Cummings KM, Stoler DL, Anderson GR.

Cancer Genet Cytogenet. 2006 Jul 15;168(2):98-104.

PMID:
16843098
46.

Genomic instability of human aberrant crypt foci measured by inter-(simple sequence repeat) PCR and array-CGH.

Alrawi SJ, Carroll RE, Hill HC, Gibbs JF, Tan D, Brenner BM, Nowak NJ, Swede H, Stoler DL, Anderson GR.

Mutat Res. 2006 Oct 10;601(1-2):30-8. Epub 2006 Jun 27.

PMID:
16806294
47.

Array CGH analysis of pediatric medulloblastomas.

Rossi MR, Conroy J, McQuaid D, Nowak NJ, Rutka JT, Cowell JK.

Genes Chromosomes Cancer. 2006 Mar;45(3):290-303.

PMID:
16320246
48.

Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

Lassman AB, Rossi MR, Raizer JJ, Abrey LE, Lieberman FS, Grefe CN, Lamborn K, Pao W, Shih AH, Kuhn JG, Wilson R, Nowak NJ, Cowell JK, DeAngelis LM, Wen P, Gilbert MR, Chang S, Yung WA, Prados M, Holland EC.

Clin Cancer Res. 2005 Nov 1;11(21):7841-50. Erratum in: Clin Cancer Res. 2006 Jan 1;12(1):322. Razier, Jeffrey R [corrected to Raizer, Jeffrey J].

49.

Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line.

Cowell JK, LaDuca J, Rossi MR, Burkhardt T, Nowak NJ, Matsui S.

Cancer Genet Cytogenet. 2005 Nov;163(1):23-9.

PMID:
16271952
50.

Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York.

Varma G, Varma R, Huang H, Pryshchepava A, Groth J, Fleming D, Nowak NJ, McQuaid D, Conroy J, Mahoney M, Moysich K, Falkner KL, Geradts J.

Br J Cancer. 2005 Sep 19;93(6):699-708.

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