Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 50

1.

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance.

Hofman J, Sorf A, Vagiannis D, Sucha S, Novotna E, Kammerer S, Küpper JH, Ceckova M, Staud F.

Drug Metab Dispos. 2019 Jul;47(7):699-709. doi: 10.1124/dmd.119.086975. Epub 2019 May 8.

PMID:
31068367
2.

Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters.

Sorf A, Novotna E, Hofman J, Morell A, Staud F, Wsol V, Ceckova M.

Biochem Pharmacol. 2019 May;163:290-298. doi: 10.1016/j.bcp.2019.02.035. Epub 2019 Feb 28.

PMID:
30826329
3.

Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3.

Bukum N, Novotna E, Morell A, Hofman J, Wsol V.

Chem Biol Interact. 2019 Apr 1;302:101-107. doi: 10.1016/j.cbi.2019.01.026. Epub 2019 Jan 28.

PMID:
30703376
4.

Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment.

Novotná E, Büküm N, Hofman J, Flaxová M, Kouklíková E, Louvarová D, Wsól V.

Biochem Pharmacol. 2018 Oct;156:22-31. doi: 10.1016/j.bcp.2018.08.001. Epub 2018 Aug 3.

PMID:
30077642
5.

Initial characterization of human DHRS1 (SDR19C1), a member of the short-chain dehydrogenase/reductase superfamily.

Zemanová L, Navrátilová H, Andrýs R, Šperková K, Andrejs J, Kozáková K, Meier M, Möller G, Novotná E, Šafr M, Adamski J, Wsól V.

J Steroid Biochem Mol Biol. 2019 Jan;185:80-89. doi: 10.1016/j.jsbmb.2018.07.013. Epub 2018 Jul 18.

PMID:
30031147
6.

Aldo-keto reductase 1C3 (AKR1C3): a missing piece of the puzzle in the dinaciclib interaction profile.

Novotná E, Büküm N, Hofman J, Flaxová M, Kouklíková E, Louvarová D, Wsól V.

Arch Toxicol. 2018 Sep;92(9):2845-2857. doi: 10.1007/s00204-018-2258-0. Epub 2018 Jul 10.

PMID:
29992508
7.

Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings.

Kuca K, Karasova JZ, Soukup O, Kassa J, Novotna E, Sepsova V, Horova A, Pejchal J, Hrabinova M, Vodakova E, Jun D, Nepovimova E, Valis M, Musilek K.

Drug Des Devel Ther. 2018 Mar 9;12:505-512. doi: 10.2147/DDDT.S133038. eCollection 2018.

8.

Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death.

Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J.

Free Radic Biol Med. 2017 Nov;112:253-266. doi: 10.1016/j.freeradbiomed.2017.07.033. Epub 2017 Jul 31.

PMID:
28774815
9.

Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity.

Novotná E, Waisser K, Kuneš J, Palát K, Skálová L, Szotáková B, Buchta V, Stolaříková J, Ulmann V, Pávová M, Weber J, Komrsková J, Hašková P, Vokřál I, Wsól V.

Arch Pharm (Weinheim). 2017 Aug;350(8). doi: 10.1002/ardp.201700020. Epub 2017 Jun 21.

PMID:
28635184
10.

Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.

Zemanova L, Hofman J, Novotna E, Musilek K, Lundova T, Havrankova J, Hostalkova A, Chlebek J, Cahlikova L, Wsol V.

J Nat Prod. 2015 Nov 25;78(11):2666-74. doi: 10.1021/acs.jnatprod.5b00616. Epub 2015 Nov 3.

PMID:
26529431
11.

Salicylanilide diethyl phosphates as potential inhibitors of some mycobacterial enzymes.

Krátký M, Novotná E, Saxena S, Yogeeswari P, Sriram D, Švarcová M, Vinšová J.

ScientificWorldJournal. 2014;2014:703053. doi: 10.1155/2014/703053. Epub 2014 Nov 4.

12.

Synthesis and biological activity of new salicylanilide N,N-disubstituted carbamates and thiocarbamates.

Krátký M, Volková M, Novotná E, Trejtnar F, Stolaříková J, Vinšová J.

Bioorg Med Chem. 2014 Aug 1;22(15):4073-82. doi: 10.1016/j.bmc.2014.05.064. Epub 2014 Jun 5.

PMID:
24953953
13.

Anthracycline resistance mediated by reductive metabolism in cancer cells: the role of aldo-keto reductase 1C3.

Hofman J, Malcekova B, Skarka A, Novotna E, Wsol V.

Toxicol Appl Pharmacol. 2014 Aug 1;278(3):238-48. doi: 10.1016/j.taap.2014.04.027. Epub 2014 May 14.

PMID:
24832494
14.

Synthesis and biological activity of quaternary ammonium salt-type agents containing cholesterol and terpenes.

Novotná E, Waisser K, Kuneš J, Palát K, Buchta V, Stolaříková J, Beckert R, Wsól V.

Arch Pharm (Weinheim). 2014 Jun;347(6):381-6. doi: 10.1002/ardp.201300407. Epub 2014 Mar 24.

PMID:
24664885
15.

Ochratoxin A: developmental and reproductive toxicity-an overview.

Malir F, Ostry V, Pfohl-Leszkowicz A, Novotna E.

Birth Defects Res B Dev Reprod Toxicol. 2013 Dec;98(6):493-502. doi: 10.1002/bdrb.21091. Epub 2014 Jan 6. Review.

PMID:
24395216
16.

Salicylanilide pyrazinoates inhibit in vitro multidrug-resistant Mycobacterium tuberculosis strains, atypical mycobacteria and isocitrate lyase.

Krátký M, Vinšová J, Novotná E, Stolaříková J.

Eur J Pharm Sci. 2014 Mar 12;53:1-9. doi: 10.1016/j.ejps.2013.12.001. Epub 2013 Dec 10.

PMID:
24333643
17.

Inhibition of ATR kinase with the selective inhibitor VE-821 results in radiosensitization of cells of promyelocytic leukaemia (HL-60).

Vávrová J, Zárybnická L, Lukášová E, Řezáčová M, Novotná E, Sinkorová Z, Tichý A, Pejchal J, Durišová K.

Radiat Environ Biophys. 2013 Nov;52(4):471-9. doi: 10.1007/s00411-013-0486-5. Epub 2013 Aug 11.

PMID:
23934411
18.

Antibacterial activity of salicylanilide 4-(trifluoromethyl)-benzoates.

Krátký M, Vinšová J, Novotná E, Mandíková J, Trejtnar F, Stolaková J.

Molecules. 2013 Mar 25;18(4):3674-88. doi: 10.3390/molecules18043674.

19.

Phenyl salicylates - a new group of potential antituberculotics.

Waisser K, Novotná E, Kuneš J, Solaříková J.

Ceska Slov Farm. 2012 Dec;61(6):282-4.

PMID:
23387858
20.

DNA-dependent protein kinase and its inhibition in support of radiotherapy.

Novotná E, Tichý A, Pejchal J, Lukášová E, Salovská B, Vávrová J.

Int J Radiat Biol. 2013 Jun;89(6):416-23. doi: 10.3109/09553002.2013.767993. Epub 2013 Mar 4. Review.

PMID:
23362996
21.

Radio-sensitization of human leukaemic molt-4 cells by DNA-dependent protein kinase inhibitor, NU7026.

Tichý A, Novotná E, Durisová K, Salovská B, Sedlaríková R, Pejchal J, Zárybnická L, Vávrová J, Sinkorová Z, Rezácová M.

Acta Medica (Hradec Kralove). 2012;55(2):66-73.

22.

Synthesis and in vitro antimycobacterial and isocitrate lyase inhibition properties of novel 2-methoxy-2'-hydroxybenzanilides, their thioxo analogues and benzoxazoles.

Kozic J, Novotná E, Volková M, Stolaříková J, Trejtnar F, Wsól V, Vinšová J.

Eur J Med Chem. 2012 Oct;56:108-19. doi: 10.1016/j.ejmech.2012.08.016. Epub 2012 Aug 16.

PMID:
22960697
23.

Synthesis and in vitro antimycobacterial activity of 2-methoxybenzanilides and their thioxo analogues.

Kozic J, Novotná E, Volková M, Stolaříková J, Trejtnar F, Vinšová J.

Eur J Med Chem. 2012 Oct;56:387-95. doi: 10.1016/j.ejmech.2012.07.044. Epub 2012 Aug 4.

PMID:
22907036
24.

Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase.

Krátký M, Vinšová J, Novotná E, Mandíková J, Wsól V, Trejtnar F, Ulmann V, Stolaříková J, Fernandes S, Bhat S, Liu JO.

Tuberculosis (Edinb). 2012 Sep;92(5):434-9. doi: 10.1016/j.tube.2012.06.001. Epub 2012 Jul 4.

PMID:
22765970
25.

Activation of p38 MAPK and expression of TGF-β1 in rat colon enterocytes after whole body γ-irradiation.

Pejchal J, Novotný J, Mařák V, Osterreicher J, Tichý A, Vávrová J, Sinkorová Z, Zárybnická L, Novotná E, Chládek J, Babicová A, Kubelková K, Kuča K.

Int J Radiat Biol. 2012 Apr;88(4):348-58. doi: 10.3109/09553002.2012.654044. Epub 2012 Feb 6.

PMID:
22233094
26.

Haplotypic arrangement in CYP3A locus is associated with side effects of proliferative signal inhibitors in renal transplant recipients.

Bandur S, Petrasek J, Hribova P, Novotna E, Brabcova I, Viklicky O.

Transplantation. 2011 Jan 15;91(1):e1-2. doi: 10.1097/TP.0b013e3181fa94a0. No abstract available.

PMID:
21441846
27.

Association of advanced vasculopathy and transforming growth factor-beta1 gene expression with immunoglobulin A nephropathy progression.

Brabcova I, Tesar V, Honsova E, Lodererova A, Novotna E, Maixnerova D, Merta M, Bürgelova M, Hribova P, Skibova J, Zadrazil J, Maly J, Viklicky O.

Nephrol Dial Transplant. 2011 Feb;26(2):573-9. doi: 10.1093/ndt/gfq423. Epub 2010 Jul 22.

PMID:
20650904
28.

Haplotypic structure of ABCB1/MDR1 gene modifies the risk of the acute allograft rejection in renal transplant recipients.

Bandur S, Petrasek J, Hribova P, Novotna E, Brabcova I, Viklicky O.

Transplantation. 2008 Nov 15;86(9):1206-13. doi: 10.1097/TP.0b013e318187c4d1.

PMID:
19005401
29.

[BK viral infection after renal transplantation].

Novotná E, Viklický O.

Vnitr Lek. 2008 Sep;54(9):835-41. Review. Czech.

PMID:
18924344
30.

Detection of Bronchial Neoplasia in Uranium Miners by Autofluorescence Endoscopy (SAFE-1000).

Horvath T, Horvathova M, Salajka F, Habanec B, Foretova L, Kana J, Koukalova H, Pafko P, Wurst F, Novotna E, Pecina J, Vagunda V, Vrbacky R, Talac R, Coupková H, Pacovsky Z.

Diagn Ther Endosc. 1999;5(2):91-8. doi: 10.1155/DTE.5.91.

31.

Sensitive markers of the repolarization alterations in systemic hypertension.

Andrasyova D, Regecova V, Tonkovic M, Kellerova E, Krc-Turbova Z, Novotna E.

Bratisl Lek Listy. 2001;102(11):530-5.

PMID:
11901712
32.

[Somatic and functional profiles of members of the Slovak karate team].

Dzurenkova D, Zemkova E, Hajkova M, Marcek T, Novotna E.

Bratisl Lek Listy. 2000;101(11):623-4. Slovak.

PMID:
11218964
33.

Degradation of wood by the basidiomycete Coriolopsis occidentalis.

Homolka L, Nerud F, Kofronová O, Novotná E, Machurová V.

Folia Microbiol (Praha). 1994;39(1):37-43.

PMID:
8181780
34.

[Parenteral nutrition in neonates after surgery of congenital developmental defects].

Kohoutová E, Novotná E.

Rozhl Chir. 1991 Feb;70(1-2):11-5. Czech.

PMID:
1925775
35.

[Testing bronchogenic carcinoma cells for sensitivity to cytostatics in vitro and in cell cultures].

Zatloukal P, Fremuth F, Pazourek J, Novotná E, Mĕricka O, Schützner J, Kohoutová E.

Sb Lek. 1990 Apr;92(4):118-22. Czech.

PMID:
2359968
36.

[Treatment of post-traumatic reaction of multiple injuries in children].

Kohoutová E, Chvátal L, Macík I, Varmuzková J, Novotná E, Cerbáková B.

Rozhl Chir. 1989 Sep;68(8-9):574-7. Czech.

PMID:
2814694
37.

[Indications for surgery in unilateral and bilateral enlargement of the thyroid in children].

Macík I, Stavratjevová A, Novotná E.

Rozhl Chir. 1988 Jun;67(6):396-400. Czech. No abstract available.

PMID:
3413598
38.

Effect of lipid hydroperoxides on animal proteins under conditions of storage and food preparation.

Pokorný J, Davídek J, Novotná E, Valentová H, Janitz W, Kmínek M.

Nahrung. 1986;30(3-4):416-8. No abstract available.

PMID:
3748122
39.

[Comprehensive therapy in perforated appendicitis in childhood].

Novotná E.

Rozhl Chir. 1985 Jul;64(7):500-3. Czech. No abstract available.

PMID:
4049136
40.

Reactions of oxidized lipids with protein. Part 13. Autoxidation of hexanal in presence of nonlipidic components.

Pokorný J, Kmínek M, Janitz W, Novotná E, Davídek J.

Nahrung. 1985;29(5):459-65.

PMID:
4022111
41.

[Pitfalls in childhood peritonitis].

Novotná E.

Rozhl Chir. 1984 Nov;63(11):774-7. Czech. No abstract available.

PMID:
6523282
42.

[Pyloric atresia in a newborn infant and unusual complications].

Kokes M, Nekvasil R, Novotná E.

Rozhl Chir. 1982 Sep;61(9):614-6. Czech. No abstract available.

PMID:
7179019
43.

[Pancreatic injuries in childhood].

Ludvíkovský J, Novotná E.

Rozhl Chir. 1982 Apr;61(4):215-8. Czech. No abstract available.

PMID:
7089733
44.

[Mediastinal tumors in children].

Tecl F, Novotná E, Lukásová I.

Rozhl Chir. 1980 Jul;59(7):440-2. Czech. No abstract available.

PMID:
7280847
46.
47.
48.

[Systematic identification of synthetic drugs using color reactions, and its application in the analysis of biological material].

Vecerková J, Kácl K, Novotná E, Nikolicová L.

Cesk Farm. 1965 Nov;14(9):444-57. Czech. No abstract available.

PMID:
5864263
49.

[Incidence of the sleeping activity in the EEG psychiatric patients].

Brezinová V, Novotná E.

Cesk Psychiatr. 1965 Aug;61(4):234-9. Czech. No abstract available.

PMID:
5836596
50.

ELECTROCLINICAL CORRELATIONS OF HIGH VOLTAGE ALPHA-RHYTHM IN EEG OF PSYCHIATRIC PATIENTS.

BREZINOVA V, NOVOTNA E.

Act Nerv Super (Praha). 1965;7:196-7. No abstract available.

PMID:
14319142

Supplemental Content

Loading ...
Support Center