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Items: 26

1.

VH replacement in primary immunoglobulin repertoire diversification.

Sun A, Novobrantseva TI, Coffre M, Hewitt SL, Jensen K, Skok JA, Rajewsky K, Koralov SB.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E458-66. doi: 10.1073/pnas.1418001112. Epub 2015 Jan 21.

2.

The roles of individual mammalian argonautes in RNA interference in vivo.

Ruda VM, Chandwani R, Sehgal A, Bogorad RL, Akinc A, Charisse K, Tarakhovsky A, Novobrantseva TI, Koteliansky V.

PLoS One. 2014 Jul 3;9(7):e101749. doi: 10.1371/journal.pone.0101749. eCollection 2014.

3.

Silencing of CCR2 in myocarditis.

Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M.

Eur Heart J. 2015 Jun 14;36(23):1478-88. doi: 10.1093/eurheartj/ehu225. Epub 2014 Jun 20.

4.

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

Dong Y, Love KT, Dorkin JR, Sirirungruang S, Zhang Y, Chen D, Bogorad RL, Yin H, Chen Y, Vegas AJ, Alabi CA, Sahay G, Olejnik KT, Wang W, Schroeder A, Lytton-Jean AK, Siegwart DJ, Akinc A, Barnes C, Barros SA, Carioto M, Fitzgerald K, Hettinger J, Kumar V, Novobrantseva TI, Qin J, Querbes W, Koteliansky V, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):3955-60. doi: 10.1073/pnas.1322937111. Epub 2014 Feb 10. Erratum in: Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5753.

5.

Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity.

Dolina JS, Sung SS, Novobrantseva TI, Nguyen TM, Hahn YS.

Mol Ther Nucleic Acids. 2013 Feb 19;2:e72. doi: 10.1038/mtna.2012.63.

6.

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.

Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V.

Mol Ther Nucleic Acids. 2012 Jan 24;1:e4. doi: 10.1038/mtna.2011.3.

7.

Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production.

Tosello-Trampont AC, Landes SG, Nguyen V, Novobrantseva TI, Hahn YS.

J Biol Chem. 2012 Nov 23;287(48):40161-72. doi: 10.1074/jbc.M112.417014. Epub 2012 Oct 12.

8.

RNA inhibition highlights cyclin D1 as a potential therapeutic target for mantle cell lymphoma.

Weinstein S, Emmanuel R, Jacobi AM, Abraham A, Behlke MA, Sprague AG, Novobrantseva TI, Nagler A, Peer D.

PLoS One. 2012;7(8):e43343. doi: 10.1371/journal.pone.0043343. Epub 2012 Aug 14.

9.

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation.

Hobo W, Novobrantseva TI, Fredrix H, Wong J, Milstein S, Epstein-Barash H, Liu J, Schaap N, van der Voort R, Dolstra H.

Cancer Immunol Immunother. 2013 Feb;62(2):285-97. doi: 10.1007/s00262-012-1334-1. Epub 2012 Aug 19.

PMID:
22903385
10.

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1868-77. doi: 10.1073/pnas.1116889109. Epub 2012 Jun 13.

11.

Origins of tumor-associated macrophages and neutrophils.

Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2491-6. doi: 10.1073/pnas.1113744109. Epub 2012 Jan 30.

12.

Therapeutic siRNA silencing in inflammatory monocytes in mice.

Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M.

Nat Biotechnol. 2011 Oct 9;29(11):1005-10. doi: 10.1038/nbt.1989.

13.

Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.

Basha G, Novobrantseva TI, Rosin N, Tam YY, Hafez IM, Wong MK, Sugo T, Ruda VM, Qin J, Klebanov B, Ciufolini M, Akinc A, Tam YK, Hope MJ, Cullis PR.

Mol Ther. 2011 Dec;19(12):2186-200. doi: 10.1038/mt.2011.190. Epub 2011 Oct 4.

14.

Highly effective gene transfection in vivo by alkylated polyethylenimine.

Fortune JA, Novobrantseva TI, Klibanov AM.

J Drug Deliv. 2011;2011:204058. doi: 10.1155/2011/204058. Epub 2011 Mar 21.

15.

Delivering silence: advancements in developing siRNA therapeutics.

Novobrantseva TI, Akinc A, Borodovsky A, de Fougerolles A.

Curr Opin Drug Discov Devel. 2008 Mar;11(2):217-24. Review.

PMID:
18283609
16.

Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus.

Fraenkel S, Mostoslavsky R, Novobrantseva TI, Pelanda R, Chaudhuri J, Esposito G, Jung S, Alt FW, Rajewsky K, Cedar H, Bergman Y.

Nat Immunol. 2007 Jul;8(7):715-22. Epub 2007 Jun 3.

PMID:
17546032
17.

Antibody repertoires generated by VH replacement and direct VH to JH joining.

Koralov SB, Novobrantseva TI, Königsmann J, Ehlich A, Rajewsky K.

Immunity. 2006 Jul;25(1):43-53.

18.

Attenuated liver fibrosis in the absence of B cells.

Novobrantseva TI, Majeau GR, Amatucci A, Kogan S, Brenner I, Casola S, Shlomchik MJ, Koteliansky V, Hochman PS, Ibraghimov A.

J Clin Invest. 2005 Nov;115(11):3072-82.

19.

Direct in vivo VH to JH rearrangement violating the 12/23 rule.

Koralov SB, Novobrantseva TI, Hochedlinger K, Jaenisch R, Rajewsky K.

J Exp Med. 2005 Feb 7;201(3):341-8.

20.

Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression.

López-Rodríguez C, Antos CL, Shelton JM, Richardson JA, Lin F, Novobrantseva TI, Bronson RT, Igarashi P, Rao A, Olson EN.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2392-7.

21.

Expression and functional importance of collagen-binding integrins, alpha 1 beta 1 and alpha 2 beta 1, on virus-activated T cells.

Andreasen SØ, Thomsen AR, Koteliansky VE, Novobrantseva TI, Sprague AG, de Fougerolles AR, Christensen JP.

J Immunol. 2003 Sep 15;171(6):2804-11.

22.

Expression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements.

Oberdoerffer P, Novobrantseva TI, Rajewsky K.

J Exp Med. 2003 May 5;197(9):1165-72. Epub 2003 Apr 28. Erratum in: J Exp Med. 2003 May 19;1399.

23.

Importance of innate immunity and collagen binding integrin alpha1beta1 in TNBS-induced colitis.

Fiorucci S, Mencarelli A, Palazzetti B, Sprague AG, Distrutti E, Morelli A, Novobrantseva TI, Cirino G, Koteliansky VE, de Fougerolles AR.

Immunity. 2002 Dec;17(6):769-80.

24.

Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice.

Novobrantseva TI, Martin VM, Pelanda R, Müller W, Rajewsky K, Ehlich A.

J Exp Med. 1999 Jan 4;189(1):75-88.

25.

Cloning and expression analysis of the murine lymphotoxin beta gene.

Pokholok DK, Maroulakou IG, Kuprash DV, Alimzhanov MB, Kozlov SV, Novobrantseva TI, Turetskaya RL, Green JE, Nedospasov SA.

Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):674-8.

26.

[Characteristics of murine chromosome 17 containing three tumor necrosis factor family genes, including the gene of the transmembrane subunit of lymphotoxin].

Kuprash DV, Alimzhanov MB, Pokholok DK, Kozlov SV, Novobrantseva TI, Turetskaia RL, Nedospasov SA.

Dokl Akad Nauk. 1994 Aug;337(5):683-6. Russian. No abstract available.

PMID:
7987231

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