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Items: 26

1.

Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.

Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D.

Cell. 2018 Sep 20;175(1):212-223.e17. doi: 10.1016/j.cell.2018.09.001.

PMID:
30241607
2.

Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration.

Lin H, Long JZ, Roche AM, Svensson KJ, Dou FY, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CA, Louie SM, Nomura DK, Spiegelman BM, Griffin PR, Kamenecka TM.

J Med Chem. 2018 Apr 12;61(7):3224-3230. doi: 10.1021/acs.jmedchem.8b00029. Epub 2018 Mar 22.

PMID:
29533650
3.

HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions.

Zheng J, Chang MR, Stites RE, Wang Y, Bruning JB, Pascal BD, Novick SJ, Garcia-Ordonez RD, Stayrook KR, Chalmers MJ, Dodge JA, Griffin PR.

Nat Commun. 2017 Oct 13;8(1):923. doi: 10.1038/s41467-017-00978-7.

4.

Nucleotide Binding to ARL2 in the TBCD∙ARL2∙β-Tubulin Complex Drives Conformational Changes in β-Tubulin.

Francis JW, Goswami D, Novick SJ, Pascal BD, Weikum ER, Ortlund EA, Griffin PR, Kahn RA.

J Mol Biol. 2017 Nov 24;429(23):3696-3716. doi: 10.1016/j.jmb.2017.09.016. Epub 2017 Sep 29.

PMID:
28970104
5.

Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing.

Gu X, Yan Y, Novick SJ, Kovach A, Goswami D, Ke J, Tan MHE, Wang L, Li X, de Waal PW, Webb MR, Griffin PR, Xu HE, Melcher K.

J Biol Chem. 2017 Jul 28;292(30):12653-12666. doi: 10.1074/jbc.M117.793018. Epub 2017 Jun 14.

6.

N-Arylsulfonyl Indolines as Retinoic Acid Receptor-Related Orphan Receptor γ (RORγ) Agonists.

Doebelin C, Patouret R, Garcia-Ordonez RD, Chang MR, Dharmarajan V, Kuruvilla DS, Novick SJ, Lin L, Cameron MD, Griffin PR, Kamenecka TM.

ChemMedChem. 2016 Dec 6;11(23):2607-2620. doi: 10.1002/cmdc.201600491. Epub 2016 Nov 23.

7.

Setting Alert and Action Limits in the Presence of Significant Amount of Censoring in Data.

Novick SJ, Zhao W, Yang H.

PDA J Pharm Sci Technol. 2017 1/2;71(1):20-32. doi: 10.5731/pdajpst.2016.006684. Epub 2016 Aug 11.

PMID:
27516490
8.

Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform.

Cummins DJ, Espada A, Novick SJ, Molina-Martin M, Stites RE, Espinosa JF, Broughton H, Goswami D, Pascal BD, Dodge JA, Chalmers MJ, Griffin PR.

Anal Chem. 2016 Jun 21;88(12):6607-14. doi: 10.1021/acs.analchem.6b01650. Epub 2016 Jun 13.

PMID:
27224086
9.

A new PK equivalence test for a bridging study.

Novick SJ, Zhang X, Yang H.

J Biopharm Stat. 2016;26(5):992-1002. doi: 10.1080/10543406.2016.1148712. Epub 2016 Feb 16.

PMID:
26882145
10.

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.

Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, Greene GL.

Elife. 2016 Feb 2;5. pii: e12792. doi: 10.7554/eLife.12792.

11.

Synthetic RORγt Agonists Enhance Protective Immunity.

Chang MR, Dharmarajan V, Doebelin C, Garcia-Ordonez RD, Novick SJ, Kuruvilla DS, Kamenecka TM, Griffin PR.

ACS Chem Biol. 2016 Apr 15;11(4):1012-8. doi: 10.1021/acschembio.5b00899. Epub 2016 Jan 25.

12.

Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Rodent Models of Infection.

Hoover J, Lewandowski T, Straub RJ, Novick SJ, DeMarsh P, Aubart K, Rittenhouse S, Zalacain M.

Antimicrob Agents Chemother. 2015 Oct 19;60(1):180-9. doi: 10.1128/AAC.01842-15. Print 2016 Jan.

13.

Pharmacological repression of PPARγ promotes osteogenesis.

Marciano DP, Kuruvilla DS, Boregowda SV, Asteian A, Hughes TS, Garcia-Ordonez R, Corzo CA, Khan TM, Novick SJ, Park H, Kojetin DJ, Phinney DG, Bruning JB, Kamenecka TM, Griffin PR.

Nat Commun. 2015 Jun 12;6:7443. doi: 10.1038/ncomms8443.

14.

Testing drug additivity based on monotherapies.

Yang H, Novick SJ, Zhao W.

Pharm Stat. 2015 Jul-Aug;14(4):332-40. doi: 10.1002/pst.1689. Epub 2015 May 12.

PMID:
25962689
15.

The acute extracellular flux (XF) assay to assess compound effects on mitochondrial function.

Wang R, Novick SJ, Mangum JB, Queen K, Ferrick DA, Rogers GW, Stimmel JB.

J Biomol Screen. 2015 Mar;20(3):422-9. doi: 10.1177/1087057114557621. Epub 2014 Nov 7.

PMID:
25381255
16.

Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas.

Alvizo O, Nguyen LJ, Savile CK, Bresson JA, Lakhapatri SL, Solis EO, Fox RJ, Broering JM, Benoit MR, Zimmerman SA, Novick SJ, Liang J, Lalonde JJ.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16436-41. doi: 10.1073/pnas.1411461111. Epub 2014 Nov 3.

17.

Testing assay linearity over a pre-specified range.

Yang H, Novick SJ, LeBlond D.

J Biopharm Stat. 2015;25(2):339-50. doi: 10.1080/10543406.2014.972513.

PMID:
25356663
18.

A simple test for synergy for a small number of combinations.

Novick SJ.

Stat Med. 2013 Dec 20;32(29):5145-55. doi: 10.1002/sim.5905. Epub 2013 Aug 1.

PMID:
23904140
19.

Development of a high-throughput electrophysiological assay for the human ether-à-go-go related potassium channel hERG.

Gillie DJ, Novick SJ, Donovan BT, Payne LA, Townsend C.

J Pharmacol Toxicol Methods. 2013 Jan-Feb;67(1):33-44. doi: 10.1016/j.vascn.2012.10.002. Epub 2012 Oct 26.

PMID:
23103595
20.

Pharmacovirological impact of an integrase inhibitor on human immunodeficiency virus type 1 cDNA species in vivo.

Goffinet C, Allespach I, Oberbremer L, Golden PL, Foster SA, Johns BA, Weatherhead JG, Novick SJ, Chiswell KE, Garvey EP, Keppler OT.

J Virol. 2009 Aug;83(15):7706-17. doi: 10.1128/JVI.00683-09. Epub 2009 May 20.

21.

Nonlinear blending: a useful general concept for the assessment of combination drug synergy.

Peterson JJ, Novick SJ.

J Recept Signal Transduct Res. 2007;27(2-3):125-46. Review.

PMID:
17613725
22.

Creation of a broad-range and highly stereoselective D-amino acid dehydrogenase for the one-step synthesis of D-amino acids.

Vedha-Peters K, Gunawardana M, Rozzell JD, Novick SJ.

J Am Chem Soc. 2006 Aug 23;128(33):10923-9.

23.

Increased seizure threshold and severity in young transgenic CRND8 mice.

Del Vecchio RA, Gold LH, Novick SJ, Wong G, Hyde LA.

Neurosci Lett. 2004 Sep 2;367(2):164-7.

PMID:
15331144
24.

Protein-containing hydrophobic coatings and films.

Novick SJ, Dordick JS.

Biomaterials. 2002 Jan;23(2):441-8.

PMID:
11761164
25.

Investigating the effects of polymer chemistry on activity of biocatalytic plastic materials.

Novick SJ, Dordick JS.

Biotechnol Bioeng. 2000 Jun 20;68(6):665-71.

PMID:
10799992
26.

Comparison of two hepatitis B surface antigen and two HIV-1 (p24) antigen EIA test kits with hemolyzed cadaveric blood specimens.

Novick SJ, Schrager JA, Nelson JA, Anderson ME, Baskin BL.

Transplant Proc. 1996 Oct;28(5):2925-6. No abstract available.

PMID:
8908126

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