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Items: 15

1.

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.

Zviran A, Mor N, Rais Y, Gingold H, Peles S, Chomsky E, Viukov S, Buenrostro JD, Scognamiglio R, Weinberger L, Manor YS, Krupalnik V, Zerbib M, Hezroni H, Jaitin DA, Larastiaso D, Gilad S, Benjamin S, Gafni O, Mousa A, Ayyash M, Sheban D, Bayerl J, Aguilera-Castrejon A, Massarwa R, Maza I, Hanna S, Stelzer Y, Ulitsky I, Greenleaf WJ, Tanay A, Trumpp A, Amit I, Pilpel Y, Novershtern N, Hanna JH.

Cell Stem Cell. 2019 Feb 7;24(2):328-341.e9. doi: 10.1016/j.stem.2018.11.014. Epub 2018 Dec 13.

PMID:
30554962
2.

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.

Mor N, Rais Y, Sheban D, Peles S, Aguilera-Castrejon A, Zviran A, Elinger D, Viukov S, Geula S, Krupalnik V, Zerbib M, Chomsky E, Lasman L, Shani T, Bayerl J, Gafni O, Hanna S, Buenrostro JD, Hagai T, Masika H, Vainorius G, Bergman Y, Greenleaf WJ, Esteban MA, Elling U, Levin Y, Massarwa R, Merbl Y, Novershtern N, Hanna JH.

Cell Stem Cell. 2018 Sep 6;23(3):412-425.e10. doi: 10.1016/j.stem.2018.07.004. Epub 2018 Aug 16.

3.

Dynamic stem cell states: naive to primed pluripotency in rodents and humans.

Weinberger L, Ayyash M, Novershtern N, Hanna JH.

Nat Rev Mol Cell Biol. 2016 Mar;17(3):155-69. doi: 10.1038/nrm.2015.28. Epub 2016 Feb 10. Review.

PMID:
26860365
4.

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors.

Maza I, Caspi I, Zviran A, Chomsky E, Rais Y, Viukov S, Geula S, Buenrostro JD, Weinberger L, Krupalnik V, Hanna S, Zerbib M, Dutton JR, Greenleaf WJ, Massarwa R, Novershtern N, Hanna JH.

Nat Biotechnol. 2015 Jul;33(7):769-74. doi: 10.1038/nbt.3270. Epub 2015 Jun 22.

5.

Corrigendum: Derivation of novel human ground state naive pluripotent stem cells.

Gafni O, Weinberger L, Mansour AA, Manor YS, Chomsky E, Ben-Yosef D, Kalma Y, Viukov S, Maza I, Zviran A, Rais Y, Shipony Z, Mukamel Z, Krupalnik V, Zerbib M, Geula S, Caspi I, Schneir D, Shwartz T, Gilad S, Amann-Zalcenstein D, Benjamin S, Amit I, Tanay A, Massarwa R, Novershtern N, Hanna JH.

Nature. 2015 Apr 30;520(7549):710. doi: 10.1038/nature14370. Epub 2015 Apr 1. No abstract available.

PMID:
25830888
6.

Corrigendum: Deterministic direct reprogramming of somatic cells to pluripotency.

Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH.

Nature. 2015 Apr 30;520(7549):710. doi: 10.1038/nature14369. Epub 2015 Apr 1. No abstract available.

PMID:
25830885
7.

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

Geula S, Moshitch-Moshkovitz S, Dominissini D, Mansour AA, Kol N, Salmon-Divon M, Hershkovitz V, Peer E, Mor N, Manor YS, Ben-Haim MS, Eyal E, Yunger S, Pinto Y, Jaitin DA, Viukov S, Rais Y, Krupalnik V, Chomsky E, Zerbib M, Maza I, Rechavi Y, Massarwa R, Hanna S, Amit I, Levanon EY, Amariglio N, Stern-Ginossar N, Novershtern N, Rechavi G, Hanna JH.

Science. 2015 Feb 27;347(6225):1002-6. doi: 10.1126/science.1261417. Epub 2015 Jan 1.

8.

Derivation of novel human ground state naive pluripotent stem cells.

Gafni O, Weinberger L, Mansour AA, Manor YS, Chomsky E, Ben-Yosef D, Kalma Y, Viukov S, Maza I, Zviran A, Rais Y, Shipony Z, Mukamel Z, Krupalnik V, Zerbib M, Geula S, Caspi I, Schneir D, Shwartz T, Gilad S, Amann-Zalcenstein D, Benjamin S, Amit I, Tanay A, Massarwa R, Novershtern N, Hanna JH.

Nature. 2013 Dec 12;504(7479):282-6. doi: 10.1038/nature12745. Epub 2013 Oct 30. Erratum in: Nature. 2015 Apr 30;520(7549):710.

PMID:
24172903
9.

Deterministic direct reprogramming of somatic cells to pluripotency.

Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH.

Nature. 2013 Oct 3;502(7469):65-70. doi: 10.1038/nature12587. Epub 2013 Sep 18. Erratum in: Nature. 2015 Apr 30;520(7549):710.

PMID:
24048479
10.

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.

Mansour AA, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, Krupalnik V, Zerbib M, Amann-Zalcenstein D, Maza I, Geula S, Viukov S, Holtzman L, Pribluda A, Canaani E, Horn-Saban S, Amit I, Novershtern N, Hanna JH.

Nature. 2012 Aug 16;488(7411):409-13. doi: 10.1038/nature11272.

PMID:
22801502
11.

esBAF safeguards Stat3 binding to maintain pluripotency.

Novershtern N, Hanna JH.

Nat Cell Biol. 2011 Aug 1;13(8):886-8. doi: 10.1038/ncb2311.

PMID:
21808242
12.

Physical Module Networks: an integrative approach for reconstructing transcription regulation.

Novershtern N, Regev A, Friedman N.

Bioinformatics. 2011 Jul 1;27(13):i177-85. doi: 10.1093/bioinformatics/btr222.

13.

Densely interconnected transcriptional circuits control cell states in human hematopoiesis.

Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, Dombkowski D, Evans JW, Liefeld T, Smutko JS, Chen J, Friedman N, Young RA, Golub TR, Regev A, Ebert BL.

Cell. 2011 Jan 21;144(2):296-309. doi: 10.1016/j.cell.2011.01.004.

14.

Mitochondrial processes are impaired in hereditary inclusion body myopathy.

Eisenberg I, Novershtern N, Itzhaki Z, Becker-Cohen M, Sadeh M, Willems PH, Friedman N, Koopman WJ, Mitrani-Rosenbaum S.

Hum Mol Genet. 2008 Dec 1;17(23):3663-74. doi: 10.1093/hmg/ddn261. Epub 2008 Aug 23.

PMID:
18723858
15.

A functional and regulatory map of asthma.

Novershtern N, Itzhaki Z, Manor O, Friedman N, Kaminski N.

Am J Respir Cell Mol Biol. 2008 Mar;38(3):324-36. Epub 2007 Oct 5.

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