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Items: 1 to 50 of 63

1.

Mechanisms underlying the influence of oestrogen on cardiovascular physiology in women.

Novella S, Pérez-Cremades D, Mompeón A, Hermenegildo C.

J Physiol. 2019 Oct;597(19):4873-4886. doi: 10.1113/JP278063. Epub 2019 Aug 26.

PMID:
31372994
2.

Regulatory Mechanisms of Estrogen on Vascular Ageing.

Novella S, Dantas AP, Hermenegildo C, Hellsten Y.

Oxid Med Cell Longev. 2019 Apr 28;2019:4859082. doi: 10.1155/2019/4859082. eCollection 2019. No abstract available.

3.

Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129.

Gomes CPC, Ágg B, Andova A, Arslan S, Baker A, Barteková M, Beis D, Betsou F, Wettinger SB, Bugarski B, Condorelli G, Silva GJJD, Danilin S, de Gonzalo-Calvo D, Buil A, Carmo-Fonseca M, Enguita FJ, Felekkis K, Ferdinandy P, Gyöngyösi M, Hackl M, Karaduzovic-Hadziabdic K, Hellemans J, Heymans S, Hlavackova M, Hoydal MA, Jankovic A, Jusic A, Kardassis D, Kerkelä R, Kuster GM, Lakkisto P, Leszek P, Lustrek M, Maegdefessel L, Martelli F, Novella S, O'Brien T, Papaneophytou C, Pedrazzini T, Pinet F, Popescu O, Potočnjak I, Robinson E, Sasson S, Scholz M, Simionescu M, Stoll M, Varga ZV, Vinciguerra M, Xuereb A, Yilmaz MB, Emanueli C, Devaux Y, on behalf of the EU-CardioRNA COST Action (CA17129).

Noncoding RNA. 2019 Mar 29;5(2). pii: E31. doi: 10.3390/ncrna5020031.

4.

Role of miRNA in the Regulatory Mechanisms of Estrogens in Cardiovascular Ageing.

Pérez-Cremades D, Mompeón A, Vidal-Gómez X, Hermenegildo C, Novella S.

Oxid Med Cell Longev. 2018 Dec 20;2018:6082387. doi: 10.1155/2018/6082387. eCollection 2018. Review.

5.

Microparticles harbouring Sonic hedgehog morphogen improve the vasculogenesis capacity of endothelial progenitor cells derived from myocardial infarction patients.

Bueno-Betí C, Novella S, Soleti R, Mompeón A, Vergori L, Sanchís J, Andriantsitohaina R, Martínez MC, Hermenegildo C.

Cardiovasc Res. 2019 Feb 1;115(2):409-418. doi: 10.1093/cvr/cvy189.

PMID:
30124781
6.

Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells.

Ibañez-Cabellos JS, Aguado C, Pérez-Cremades D, García-Giménez JL, Bueno-Betí C, García-López EM, Romá-Mateo C, Novella S, Hermenegildo C, Pallardó FV.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3234-3246. doi: 10.1016/j.bbadis.2018.07.010. Epub 2018 Jul 11.

7.

MicroRNA as Crucial Regulators of Gene Expression in Estradiol-Treated Human Endothelial Cells.

Vidal-Gómez X, Pérez-Cremades D, Mompeón A, Dantas AP, Novella S, Hermenegildo C.

Cell Physiol Biochem. 2018;45(5):1878-1892. doi: 10.1159/000487910. Epub 2018 Feb 28.

8.

miRNA as a New Regulatory Mechanism of Estrogen Vascular Action.

Pérez-Cremades D, Mompeón A, Vidal-Gómez X, Hermenegildo C, Novella S.

Int J Mol Sci. 2018 Feb 6;19(2). pii: E473. doi: 10.3390/ijms19020473. Review.

9.

Extracellular histones disarrange vasoactive mediators release through a COX-NOS interaction in human endothelial cells.

Pérez-Cremades D, Bueno-Betí C, García-Giménez JL, Ibañez-Cabellos JS, Hermenegildo C, Pallardó FV, Novella S.

J Cell Mol Med. 2017 Aug;21(8):1584-1592. doi: 10.1111/jcmm.13088. Epub 2017 Feb 28.

10.

Mas receptor is involved in the estrogen-receptor induced nitric oxide-dependent vasorelaxation.

Sobrino A, Vallejo S, Novella S, Lázaro-Franco M, Mompeón A, Bueno-Betí C, Walther T, Sánchez-Ferrer C, Peiró C, Hermenegildo C.

Biochem Pharmacol. 2017 Apr 1;129:67-72. doi: 10.1016/j.bcp.2017.01.012. Epub 2017 Jan 25.

PMID:
28131844
11.

Effects of asymmetric dimethylarginine on renal arteries in portal hypertension and cirrhosis.

Segarra G, Cortina B, Mauricio MD, Novella S, Lluch P, Navarrete-Navarro J, Noguera I, Medina P.

World J Gastroenterol. 2016 Dec 28;22(48):10545-10556. doi: 10.3748/wjg.v22.i48.10545.

12.

With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions.

Drechsler S, Lynch MA, Novella S, González-Navarro H, Hecimovic S, Barini E, Tucci V, Castro RE, Vandenbroucke RE, Osuchowski M, Potter PK.

Mech Ageing Dev. 2016 Dec;160:54-68. doi: 10.1016/j.mad.2016.07.005. Epub 2016 Jul 21. Review.

13.

Frailty in mouse ageing: A conceptual approach.

von Zglinicki T, Varela Nieto I, Brites D, Karagianni N, Ortolano S, Georgopoulos S, Cardoso AL, Novella S, Lepperdinger G, Trendelenburg AU, van Os R.

Mech Ageing Dev. 2016 Dec;160:34-40. doi: 10.1016/j.mad.2016.07.004. Epub 2016 Jul 18. Review.

14.

Decreased bioavailability of nitric oxide in aorta from ovariectomized senescent mice. Role of cyclooxygenase.

Vidal-Gómez X, Novella S, Pérez-Monzó I, Garabito M, Dantas AP, Segarra G, Hermenegildo C, Medina P.

Exp Gerontol. 2016 Apr;76:1-8. doi: 10.1016/j.exger.2016.01.006. Epub 2016 Jan 13.

PMID:
26774228
15.

Estradiol, acting through ERα, induces endothelial non-classic renin-angiotensin system increasing angiotensin 1-7 production.

Mompeón A, Lázaro-Franco M, Bueno-Betí C, Pérez-Cremades D, Vidal-Gómez X, Monsalve E, Gironacci MM, Hermenegildo C, Novella S.

Mol Cell Endocrinol. 2016 Feb 15;422:1-8. doi: 10.1016/j.mce.2015.11.004. Epub 2015 Nov 11.

PMID:
26562171
16.

Endothelial Progenitor Cells Predict Cardiovascular Events after Atherothrombotic Stroke and Acute Myocardial Infarction. A PROCELL Substudy.

Cuadrado-Godia E, Regueiro A, Núñez J, Díaz-Ricard M, Novella S, Oliveras A, Valverde MA, Marrugat J, Ois A, Giralt-Steinhauer E, Sanchís J, Escolar G, Hermenegildo C, Heras M, Roquer J.

PLoS One. 2015 Sep 2;10(9):e0132415. doi: 10.1371/journal.pone.0132415. eCollection 2015.

17.

Endothelial transcriptomic changes induced by oxidized low density lipoprotein disclose an up-regulation of Jak-Stat pathway.

Laguna-Fernández A, Novella S, Bueno-Betí C, Marrugat J, Hermenegildo C.

Vascul Pharmacol. 2015 Oct;73:104-14. doi: 10.1016/j.vph.2015.05.013. Epub 2015 May 29.

PMID:
26028607
18.

Mobilization of endothelial progenitor cells in acute cardiovascular events in the PROCELL study: time-course after acute myocardial infarction and stroke.

Regueiro A, Cuadrado-Godia E, Bueno-Betí C, Diaz-Ricart M, Oliveras A, Novella S, Gené GG, Jung C, Subirana I, Ortiz-Pérez JT, Roqué M, Freixa X, Núñez J, Escolar G, Marrugat J, Hermenegildo C, Valverde MA, Roquer J, Sanchis J, Heras M.

J Mol Cell Cardiol. 2015 Mar;80:146-55. doi: 10.1016/j.yjmcc.2015.01.005. Epub 2015 Jan 22.

PMID:
25619946
19.

Considering prior plausibility in clinical trials does not mean ignoring scientific evidence.

Gorski DH, Novella SP.

Trends Mol Med. 2014 Nov;20(11):600-1. doi: 10.1016/j.molmed.2014.10.001. Epub 2014 Oct 17. No abstract available.

PMID:
25439966
20.

Diminished neurogenic femoral artery vasoconstrictor response in a Zucker obese rat model: differential regulation of NOS and COX derivatives.

Martínez AC, Hernández M, Novella S, Martínez MP, Pagán RM, Hermenegildo C, García-Sacristán A, Prieto D, Benedito S.

PLoS One. 2014 Sep 12;9(9):e106372. doi: 10.1371/journal.pone.0106372. eCollection 2014.

21.

Clinical trials of integrative medicine: testing whether magic works?

Gorski DH, Novella SP.

Trends Mol Med. 2014 Sep;20(9):473-6. doi: 10.1016/j.molmed.2014.06.007. Epub 2014 Aug 20.

PMID:
25150944
22.

An affordable method to obtain cultured endothelial cells from peripheral blood.

Bueno-Betí C, Novella S, Lázaro-Franco M, Pérez-Cremades D, Heras M, Sanchís J, Hermenegildo C.

J Cell Mol Med. 2013 Nov;17(11):1475-83. doi: 10.1111/jcmm.12133. Epub 2013 Oct 1.

23.

Dynamics of serum-induced endothelial cell apoptosis in patients with myocardial infarction.

Forteza MJ, Novella S, Trapero I, Hermenegildo C, Ruiz-Sauri A, Chaustre F, Bonanad C, Oltra R, Palacios L, O'Connor JE, Chorro FJ, Bodi V.

Eur J Clin Invest. 2014 Jan;44(1):46-53. doi: 10.1111/eci.12189. Epub 2013 Nov 14.

PMID:
24116673
24.

Aging-related endothelial dysfunction in the aorta from female senescence-accelerated mice is associated with decreased nitric oxide synthase expression.

Novella S, Dantas AP, Segarra G, Vidal-Gómez X, Mompeón A, Garabito M, Hermenegildo C, Medina P.

Exp Gerontol. 2013 Nov;48(11):1329-37. doi: 10.1016/j.exger.2013.08.003. Epub 2013 Aug 13.

PMID:
23948180
25.

Acupuncture is theatrical placebo.

Colquhoun D, Novella SP.

Anesth Analg. 2013 Jun;116(6):1360-3. doi: 10.1213/ANE.0b013e31828f2d5e. No abstract available.

PMID:
23709076
26.

ALS Untangled No. 20: the Deanna protocol.

ALSUntangled Group, Fournier C, Bedlack B, Hardiman O, Heiman-Patterson T, Gutmann L, Bromberg M, Ostrow L, Carter G, Kabashi E, Bertorini T, Mozaffar T, Andersen P, Dietz J, Gamez J, Dimachkie M, Wang Y, Wicks P, Heywood J, Novella S, Rowland LP, Pioro E, Kinsley L, Mitchell K, Glass J, Sathornsumetee S, Kwiecinski H, Baker J, Atassi N, Forshew D, Ravits J, Conwit R, Jackson C, Sherman A, Dalton K, Tindall K, Gonzalez G, Robertson J, Phillips L, Benatar M, Sorenson E, Shoesmith C, Nash S, Maragakis N, Moore D, Caress J, Boylan K, Armon C, Grosso M, Gerecke B, Wymer J, Oskarsson B, Bowser R, Drory V, Shefner J, Lechtzin N, Leitner M, Miller R, Mitsumoto H, Levine T, Russell J, Sharma K, Saperstein D, McClusky L, MacGowan D, Licht J, Verma A, Strong M, Lomen-Hoerth C, Tandan R, Rivner M, Kolb S, Polak M, Rudnicki S, Kittrell P, Quereshi M, Sachs G, Pattee G, Weiss M, Kissel J, Goldstein J, Rothstein J, Pastula D, Gleb L, Ogino M, Rosenfeld J, Carmi E, Oster C, Barkhaus P, Valor E.

Amyotroph Lateral Scler Frontotemporal Degener. 2013 May;14(4):319-23. doi: 10.3109/21678421.2013.788405. Epub 2013 May 2. Review. No abstract available.

PMID:
23638638
27.

Complete blockade of the vasorelaxant effects of angiotensin-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas.

Peiró C, Vallejo S, Gembardt F, Palacios E, Novella S, Azcutia V, Rodríguez-Mañas L, Hermenegildo C, Sánchez-Ferrer CF, Walther T.

J Physiol. 2013 May 1;591(9):2275-85. doi: 10.1113/jphysiol.2013.251413. Epub 2013 Mar 4.

28.

Estradiol, acting through estrogen receptor alpha, restores dimethylarginine dimethylaminohydrolase activity and nitric oxide production in oxLDL-treated human arterial endothelial cells.

Novella S, Laguna-Fernández A, Lázaro-Franco M, Sobrino A, Bueno-Betí C, Tarín JJ, Monsalve E, Sanchís J, Hermenegildo C.

Mol Cell Endocrinol. 2013 Jan 5;365(1):11-6. doi: 10.1016/j.mce.2012.08.020. Epub 2012 Sep 7.

PMID:
22982060
29.

Vascular Aging in Women: is Estrogen the Fountain of Youth?

Novella S, Dantas AP, Segarra G, Medina P, Hermenegildo C.

Front Physiol. 2012 Jun 6;3:165. doi: 10.3389/fphys.2012.00165. eCollection 2012.

30.

Effects of estrogen on vascular inflammation: a matter of timing.

Novella S, Heras M, Hermenegildo C, Dantas AP.

Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):2035-42. doi: 10.1161/ATVBAHA.112.250308. Epub 2012 Jun 7.

PMID:
22679310
31.

Endothelial and neural factors functionally involved in the modulation of noradrenergic vasoconstriction in healthy pig internal mammary artery.

Pagán RM, Martínez AC, Hernández M, Martínez MP, García-Sacristán A, Correa C, Novella S, Hermenegildo C, Prieto D, Benedito S.

Biochem Pharmacol. 2012 Apr 1;83(7):882-92. doi: 10.1016/j.bcp.2011.12.038. Epub 2012 Jan 11.

PMID:
22260985
32.

Aging enhances contraction to thromboxane A2 in aorta from female senescence-accelerated mice.

Novella S, Dantas AP, Segarra G, Novensa L, Heras M, Hermenegildo C, Medina P.

Age (Dordr). 2013 Feb;35(1):117-28. doi: 10.1007/s11357-011-9337-y. Epub 2011 Nov 19.

33.

Aging negatively affects estrogens-mediated effects on nitric oxide bioavailability by shifting ERα/ERβ balance in female mice.

Novensà L, Novella S, Medina P, Segarra G, Castillo N, Heras M, Hermenegildo C, Dantas AP.

PLoS One. 2011;6(9):e25335. doi: 10.1371/journal.pone.0025335. Epub 2011 Sep 22.

34.

Autism and the amygdala: commentary on Hewitson and coauthors (2010).

Novella S, Hines T.

Acta Neurobiol Exp (Wars). 2011;71(1):178-9; author reply 180-1. No abstract available.

35.

Gathering of aging and estrogen withdrawal in vascular dysfunction of senescent accelerated mice.

Novella S, Dantas AP, Segarra G, Novensà L, Bueno C, Heras M, Hermenegildo C, Medina P.

Exp Gerontol. 2010 Nov;45(11):868-74. doi: 10.1016/j.exger.2010.07.007. Epub 2010 Aug 12.

PMID:
20708673
36.

Estradiol induces endothelial cell migration and proliferation through estrogen receptor-enhanced RhoA/ROCK pathway.

Oviedo PJ, Sobrino A, Laguna-Fernandez A, Novella S, Tarín JJ, García-Pérez MA, Sanchís J, Cano A, Hermenegildo C.

Mol Cell Endocrinol. 2011 Mar 30;335(2):96-103. doi: 10.1016/j.mce.2010.06.020. Epub 2010 Jul 6.

PMID:
20615453
37.

Progestogens reduce thromboxane production by cultured human endothelial cells.

Oviedo PJ, Sobrino A, Novella S, Rius C, Laguna-Fernandez A, García-Pérez MA, Tarín JJ, Cano A, Hermenegildo C.

Climacteric. 2011 Feb;14(1):41-8. doi: 10.3109/13697131003602496. Epub 2010 May 5.

PMID:
20443717
38.

Estradiol selectively stimulates endothelial prostacyclin production through estrogen receptor-{alpha}.

Sobrino A, Oviedo PJ, Novella S, Laguna-Fernandez A, Bueno C, García-Pérez MA, Tarín JJ, Cano A, Hermenegildo C.

J Mol Endocrinol. 2010 Apr;44(4):237-46. doi: 10.1677/JME-09-0112. Epub 2010 Jan 28.

PMID:
20110403
39.

Estradiol stimulates vasodilatory and metabolic pathways in cultured human endothelial cells.

Sobrino A, Mata M, Laguna-Fernandez A, Novella S, Oviedo PJ, García-Pérez MA, Tarín JJ, Cano A, Hermenegildo C.

PLoS One. 2009 Dec 14;4(12):e8242. doi: 10.1371/journal.pone.0008242.

40.

Clinical findings in MuSK-antibody positive myasthenia gravis: a U.S. experience.

Pasnoor M, Wolfe GI, Nations S, Trivedi J, Barohn RJ, Herbelin L, McVey A, Dimachkie M, Kissel J, Walsh R, Amato A, Mozaffar T, Hungs M, Chui L, Goldstein J, Novella S, Burns T, Phillips L, Claussen G, Young A, Bertorini T, Oh S.

Muscle Nerve. 2010 Mar;41(3):370-4. doi: 10.1002/mus.21533.

PMID:
19882635
41.

Rituximab in the management of refractory myasthenia gravis.

Zebardast N, Patwa HS, Novella SP, Goldstein JM.

Muscle Nerve. 2010 Mar;41(3):375-8. doi: 10.1002/mus.21521.

PMID:
19852027
42.

Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III.

Kaufmann P, Thompson JL, Levy G, Buchsbaum R, Shefner J, Krivickas LS, Katz J, Rollins Y, Barohn RJ, Jackson CE, Tiryaki E, Lomen-Hoerth C, Armon C, Tandan R, Rudnicki SA, Rezania K, Sufit R, Pestronk A, Novella SP, Heiman-Patterson T, Kasarskis EJ, Pioro EP, Montes J, Arbing R, Vecchio D, Barsdorf A, Mitsumoto H, Levin B; QALS Study Group.

Ann Neurol. 2009 Aug;66(2):235-44. doi: 10.1002/ana.21743.

43.

Are the serum levels of sCD40L modified by raloxifene in postmenopausal women?

Oviedo PJ, Hermenegildo C, Novella S, Tarín JJ, Cano A.

Eur J Obstet Gynecol Reprod Biol. 2008 Oct;140(2):296-7. doi: 10.1016/j.ejogrb.2008.05.001. Epub 2008 Jun 25. No abstract available.

PMID:
18583017
44.

A debate: homeopathy--quackery or a key to the future of medicine?

Novella S, Roy R, Marcus D, Bell IR, Davidovitch N, Saine A.

J Altern Complement Med. 2008 Jan-Feb;14(1):9-15. doi: 10.1089/acm.2007.0770. Review. No abstract available.

PMID:
18199017
45.

Homeopathy--quackery or a key to the future of medicine?

Gold PW, Novella S, Roy R, Marcus D, Bell I, Davidovitch N, Saine A.

Homeopathy. 2008 Jan;97(1):28-33. doi: 10.1016/j.homp.2007.12.002.

PMID:
18194763
46.

HIV denial in the Internet era.

Smith TC, Novella SP.

PLoS Med. 2007 Aug;4(8):e256. No abstract available.

47.

Plasma levels and vascular effects of vasopressin in patients undergoing coronary artery bypass grafting.

Novella S, Martínez AC, Pagán RM, Hernández M, García-Sacristán A, González-Pinto A, González-Santos JM, Benedito S.

Eur J Cardiothorac Surg. 2007 Jul;32(1):69-76. Epub 2007 May 15.

PMID:
17507236
48.

Aspirin and COX-2 inhibitor nimesulide potentiate adrenergic contractions of human gastroepiploic artery.

Aldasoro M, Mauricio MD, Serna E, Cortina B, Medina P, Segarra G, Novella S, Vila JM.

Am J Hypertens. 2007 May;20(5):514-9.

PMID:
17485013
49.

A case of inherited erythromelalgia.

Novella SP, Hisama FM, Dib-Hajj SD, Waxman SG.

Nat Clin Pract Neurol. 2007 Apr;3(4):229-34.

PMID:
17410110
50.

Role of Ca2+-activated K+ channels on adrenergic responses of human saphenous vein.

Mauricio MD, Serna E, Cortina B, Novella S, Segarra G, Aldasoro M, Martínez-León JB, Vila JM.

Am J Hypertens. 2007 Jan;20(1):78-82.

PMID:
17198916

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