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Items: 14

1.

Changes in Nicotine Metabolite Ratio among Daily Smokers receiving Treatment for Alcohol Use Disorder.

Dermody SS, Hendershot CS, Andrade AK, Novalen M, Tyndale RF.

Nicotine Tob Res. 2018 Dec 17. doi: 10.1093/ntr/nty265. [Epub ahead of print]

PMID:
30561731
2.

A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine.

Taghavi T, Novalen M, Lerman C, George TP, Tyndale RF.

Cancer Epidemiol Biomarkers Prev. 2018 Aug;27(8):882-891. doi: 10.1158/1055-9965.EPI-18-0018. Epub 2018 May 31.

3.

Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment.

Jukić MM, Opel N, Ström J, Carrillo-Roa T, Miksys S, Novalen M, Renblom A, Sim SC, Peñas-Lledó EM, Courtet P, Llerena A, Baune BT, de Quervain DJ, Papassotiropoulos A, Tyndale RF, Binder EB, Dannlowski U, Ingelman-Sundberg M.

Mol Psychiatry. 2017 Aug;22(8):1224. doi: 10.1038/mp.2017.93. Epub 2017 Apr 18.

PMID:
28416806
4.

Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment.

Jukić MM, Opel N, Ström J, Carrillo-Roa T, Miksys S, Novalen M, Renblom A, Sim SC, Peñas-Lledó EM, Courtet P, Llerena A, Baune BT, de Quervain DJ, Papassotiropoulos A, Tyndale RF, Binder EB, Dannlowski U, Ingelman-Sundberg M.

Mol Psychiatry. 2017 Aug;22(8):1155-1163. doi: 10.1038/mp.2016.204. Epub 2016 Nov 29. Erratum in: Mol Psychiatry. 2017 Aug;22(8):1224.

PMID:
27895323
5.

Variation in CYP2A6 and tobacco dependence throughout adolescence and in young adult smokers.

Chenoweth MJ, Sylvestre MP, Contreras G, Novalen M, O'Loughlin J, Tyndale RF.

Drug Alcohol Depend. 2016 Jan 1;158:139-46. doi: 10.1016/j.drugalcdep.2015.11.017. Epub 2015 Nov 21.

6.

The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio.

Chenoweth MJ, Schnoll RA, Novalen M, Hawk LW Jr, George TP, Cinciripini PM, Lerman C, Tyndale RF.

Nicotine Tob Res. 2016 Apr;18(4):491-5. doi: 10.1093/ntr/ntv125. Epub 2015 Jun 11.

7.

Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation.

Tanner JA, Novalen M, Jatlow P, Huestis MA, Murphy SE, Kaprio J, Kankaanpää A, Galanti L, Stefan C, George TP, Benowitz NL, Lerman C, Tyndale RF.

Cancer Epidemiol Biomarkers Prev. 2015 Aug;24(8):1239-46. doi: 10.1158/1055-9965.EPI-14-1381. Epub 2015 May 26.

8.

Test-Retest Reliability and Stability of the Nicotine Metabolite Ratio Among Treatment-Seeking Smokers.

Hamilton DA, Mahoney MC, Novalen M, Chenoweth MJ, Heitjan DF, Lerman C, Tyndale RF, Hawk LW Jr.

Nicotine Tob Res. 2015 Dec;17(12):1505-9. doi: 10.1093/ntr/ntv031. Epub 2015 Mar 1.

9.

Known and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokers.

Chenoweth MJ, Novalen M, Hawk LW Jr, Schnoll RA, George TP, Cinciripini PM, Lerman C, Tyndale RF.

Cancer Epidemiol Biomarkers Prev. 2014 Sep;23(9):1773-82. doi: 10.1158/1055-9965.EPI-14-0427. Epub 2014 Jul 10.

10.

Nicotine pharmacokinetics in rats is altered as a function of age, impacting the interpretation of animal model data.

Craig EL, Zhao B, Cui JZ, Novalen M, Miksys S, Tyndale RF.

Drug Metab Dispos. 2014 Sep;42(9):1447-55. doi: 10.1124/dmd.114.058719. Epub 2014 Jun 30.

11.

12-OH-nevirapine sulfate, formed in the skin, is responsible for nevirapine-induced skin rash.

Sharma AM, Novalen M, Tanino T, Uetrecht JP.

Chem Res Toxicol. 2013 May 20;26(5):817-27. doi: 10.1021/tx400098z. Epub 2013 May 3.

PMID:
23590230
12.

Bioactivation of nevirapine to a reactive quinone methide: implications for liver injury.

Sharma AM, Li Y, Novalen M, Hayes MA, Uetrecht J.

Chem Res Toxicol. 2012 Aug 20;25(8):1708-19. doi: 10.1021/tx300172s. Epub 2012 Jul 26.

13.

Animal models of idiosyncratic drug reactions.

Ng W, Lobach AR, Zhu X, Chen X, Liu F, Metushi IG, Sharma A, Li J, Cai P, Ip J, Novalen M, Popovic M, Zhang X, Tanino T, Nakagawa T, Li Y, Uetrecht J.

Adv Pharmacol. 2012;63:81-135. doi: 10.1016/B978-0-12-398339-8.00003-3. Review.

PMID:
22776640
14.

Reproducibility of the nicotine metabolite ratio in cigarette smokers.

St Helen G, Novalen M, Heitjan DF, Dempsey D, Jacob P 3rd, Aziziyeh A, Wing VC, George TP, Tyndale RF, Benowitz NL.

Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1105-14. doi: 10.1158/1055-9965.EPI-12-0236. Epub 2012 May 2.

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