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Items: 1 to 50 of 82

1.

Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish.

Da'as SI, Thanassoulas A, Calver BL, Beck K, Salem R, Saleh A, Kontogianni I, Al-Maraghi A, Nasrallah GK, Safieh-Garabedian B, Toft E, Nounesis G, Lai FA, Nomikos M.

Ann N Y Acad Sci. 2019 Jul;1448(1):19-29. doi: 10.1111/nyas.14033. Epub 2019 Apr 2.

PMID:
30937913
2.

Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction.

Da'as SI, Fakhro K, Thanassoulas A, Krishnamoorthy N, Saleh A, Calver BL, Safieh-Garabedian B, Toft E, Nounesis G, Lai FA, Nomikos M.

Biochem J. 2018 Dec 14;475(24):3933-3948. doi: 10.1042/BCJ20180685.

PMID:
30446606
3.

Impact of spherical nanoparticles on nematic order parameters.

Kyrou C, Kralj S, Panagopoulou M, Raptis Y, Nounesis G, Lelidis I.

Phys Rev E. 2018 Apr;97(4-1):042701. doi: 10.1103/PhysRevE.97.042701.

PMID:
29758630
4.

Effect of high pressure on structural modifications and enzymatic activity of a purified X-prolyl dipeptidyl aminopeptidase from Streptococcus thermophilus.

Giannoglou M, Alexandrakis Z, Stavros P, Katsaros G, Katapodis P, Nounesis G, Taoukis P.

Food Chem. 2018 May 15;248:304-311. doi: 10.1016/j.foodchem.2017.12.037. Epub 2017 Dec 11.

PMID:
29329859
5.

Designed positively charged cyclodextrin hosts with enhanced binding of penicillins as carriers for the delivery of antibiotics: The case of oxacillin.

Agnes M, Thanassoulas A, Stavropoulos P, Nounesis G, Miliotis G, Miriagou V, Athanasiou E, Benkovics G, Malanga M, Yannakopoulou K.

Int J Pharm. 2017 Oct 15;531(2):480-491. doi: 10.1016/j.ijpharm.2017.04.080. Epub 2017 May 1.

PMID:
28473235
6.

Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function.

Nomikos M, Thanassoulas A, Beck K, Theodoridou M, Kew J, Kashir J, Calver BL, Matthews E, Rizkallah P, Sideratou Z, Nounesis G, Lai FA.

FEBS J. 2016 Dec;283(24):4502-4514. doi: 10.1111/febs.13939. Epub 2016 Nov 15.

7.

Electrocaloric and elastocaloric effects in soft materials.

Trček M, Lavrič M, Cordoyiannis G, Zalar B, Rožič B, Kralj S, Tzitzios V, Nounesis G, Kutnjak Z.

Philos Trans A Math Phys Eng Sci. 2016 Aug 13;374(2074). pii: 20150301. doi: 10.1098/rsta.2015.0301.

8.

HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses.

Papageorgiou AC, Adam PS, Stavros P, Nounesis G, Meijers R, Petratos K, Vorgias CE.

Extremophiles. 2016 Sep;20(5):695-709. doi: 10.1007/s00792-016-0859-1. Epub 2016 Jun 24.

PMID:
27342116
9.

Influence of precipitating agents on thermodynamic parameters of protein crystallization solutions.

Stavros P, Saridakis E, Nounesis G.

Biopolymers. 2016 Sep;105(9):642-52. doi: 10.1002/bip.22860.

PMID:
27114109
10.

The stability of the TIM-barrel domain of a psychrophilic chitinase.

Stavros P, Malecki PH, Theodoridou M, Rypniewski W, Vorgias CE, Nounesis G.

Biochem Biophys Rep. 2015 Jul 30;3:108-116. doi: 10.1016/j.bbrep.2015.07.016. eCollection 2015 Sep.

11.

Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease.

Vassilakopoulou V, Calver BL, Thanassoulas A, Beck K, Hu H, Buntwal L, Smith A, Theodoridou M, Kashir J, Blayney L, Livaniou E, Nounesis G, Lai FA, Nomikos M.

Biochim Biophys Acta. 2015 Nov;1850(11):2168-76. doi: 10.1016/j.bbagen.2015.07.001. Epub 2015 Jul 9.

PMID:
26164367
12.

Nanoparticle-induced twist-grain boundary phase.

Trček M, Cordoyiannis G, Tzitzios V, Kralj S, Nounesis G, Lelidis I, Kutnjak Z.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Sep;90(3):032501. Epub 2014 Sep 2.

PMID:
25314459
13.

Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes.

Nomikos M, Sanders JR, Theodoridou M, Kashir J, Matthews E, Nounesis G, Lai FA, Swann K.

Mol Hum Reprod. 2014 Oct;20(10):938-47. doi: 10.1093/molehr/gau056. Epub 2014 Jul 23.

14.

Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death.

Nomikos M, Thanassoulas A, Beck K, Vassilakopoulou V, Hu H, Calver BL, Theodoridou M, Kashir J, Blayney L, Livaniou E, Rizkallah P, Nounesis G, Lai FA.

FEBS Lett. 2014 Aug 25;588(17):2898-902. doi: 10.1016/j.febslet.2014.07.007. Epub 2014 Jul 15.

15.

Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation.

Nomikos M, Theodoridou M, Elgmati K, Parthimos D, Calver BL, Buntwal L, Nounesis G, Swann K, Lai FA.

Mol Hum Reprod. 2014 Jun;20(6):489-98. doi: 10.1093/molehr/gau011. Epub 2014 Jan 29.

16.

Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization.

Theodoridou M, Nomikos M, Parthimos D, Gonzalez-Garcia JR, Elgmati K, Calver BL, Sideratou Z, Nounesis G, Swann K, Lai FA.

Mol Hum Reprod. 2013 Dec;19(12):852-64. doi: 10.1093/molehr/gat070. Epub 2013 Oct 23.

17.

CdSe nanoparticles dispersed in ferroelectric smectic liquid crystals: effects upon the smectic order and the smectic-A to chiral smectic-C phase transition.

Thanassoulas A, Karatairi E, Cordoyiannis G, Kutnjak Z, Tzitzios V, Lelidis I, Nounesis G.

Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Sep;88(3):032504. Epub 2013 Sep 18.

PMID:
24125282
18.

Effect of anisotropic MoS2 nanoparticles on the blue phase range of a chiral liquid crystal.

Lavrič M, Cordoyiannis G, Kralj S, Tzitzios V, Nounesis G, Kutnjak Z.

Appl Opt. 2013 Aug 1;52(22):E47-52. doi: 10.1364/AO.52.000E47.

PMID:
23913087
19.

ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor.

Blayney L, Beck K, MacDonald E, D'Cruz L, Nomikos M, Griffiths J, Thanassoulas A, Nounesis G, Lai FA.

Biochim Biophys Acta. 2013 Oct;1830(10):4426-32. doi: 10.1016/j.bbagen.2013.05.038. Epub 2013 Jun 6.

PMID:
23747301
20.

Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility.

Nomikos M, Yu Y, Elgmati K, Theodoridou M, Campbell K, Vassilakopoulou V, Zikos C, Livaniou E, Amso N, Nounesis G, Swann K, Lai FA.

Fertil Steril. 2013 Jan;99(1):76-85. doi: 10.1016/j.fertnstert.2012.08.035. Epub 2012 Sep 21.

21.

Studies on the essential intramolecular interaction between the A1 and A2 domains of von Willebrand factor.

Karoulia Z, Papadopoulos G, Nomikos M, Thanassoulas A, Papadopoulou TC, Nounesis G, Kontou M, Stathopoulos C, Leonidas DD.

Protein Pept Lett. 2013 Feb;20(2):231-40.

PMID:
22973838
22.

Insulin complexes with PEGylated basic oligopeptides.

Tsiourvas D, Sideratou Z, Sterioti N, Papadopoulos A, Nounesis G, Paleos CM.

J Colloid Interface Sci. 2012 Oct 15;384(1):61-72. doi: 10.1016/j.jcis.2012.06.068. Epub 2012 Jul 4.

PMID:
22832094
23.

Monolithically integrated Mach-Zehnder biosensors for real-time label-free monitoring of biomolecular reactions.

Makarona E, Petrou PS, Bourkoula A, Botsialas A, Kitsara M, Kakabakos SE, Stoffer R, Jobst G, Nounesis G, Raptis I, Misiakos K.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:7654-7. doi: 10.1109/IEMBS.2011.6091886.

PMID:
22256111
24.

PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2).

Yu Y, Nomikos M, Theodoridou M, Nounesis G, Lai FA, Swann K.

Mol Biol Cell. 2012 Jan;23(2):371-80. doi: 10.1091/mbc.E11-08-0687. Epub 2011 Nov 23.

25.

Novel regulation of PLCζ activity via its XY-linker.

Nomikos M, Elgmati K, Theodoridou M, Georgilis A, Gonzalez-Garcia JR, Nounesis G, Swann K, Lai FA.

Biochem J. 2011 Sep 15;438(3):427-32. doi: 10.1042/BJ20110953.

26.

Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region.

Nomikos M, Elgmati K, Theodoridou M, Calver BL, Nounesis G, Swann K, Lai FA.

J Cell Sci. 2011 Aug 1;124(Pt 15):2582-90. doi: 10.1242/jcs.083485. Epub 2011 Jul 5.

27.

Thermal and chemical denaturation of the BRCT functional module of human 53BP1.

Thanassoulas A, Nomikos M, Theodoridou M, Stavros P, Mastellos D, Nounesis G.

Int J Biol Macromol. 2011 Oct 1;49(3):297-304. doi: 10.1016/j.ijbiomac.2011.05.001. Epub 2011 May 11.

PMID:
21600917
28.

Nucleic acid-lipid membrane interactions studied by DSC.

Giatrellis S, Nounesis G.

J Pharm Bioallied Sci. 2011 Jan;3(1):70-6. doi: 10.4103/0975-7406.76470.

29.

Complexation of lysozyme with poly(sodium(sulfamate-carboxylate)isoprene).

Karayianni M, Pispas S, Chryssikos GD, Gionis V, Giatrellis S, Nounesis G.

Biomacromolecules. 2011 May 9;12(5):1697-706. doi: 10.1021/bm200066t. Epub 2011 Mar 16.

PMID:
21410146
30.

Theoretical and experimental study of the nanoparticle-driven blue phase stabilisation.

Rožič B, Tzitzios V, Karatairi E, Tkalec U, Nounesis G, Kutnjak Z, Cordoyiannis G, Rosso R, Virga EG, Muševič I, Kralj S.

Eur Phys J E Soft Matter. 2011 Feb;34(2):17. doi: 10.1140/epje/i2011-11017-8. Epub 2011 Feb 22.

PMID:
21340674
31.

Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ.

Nomikos M, Elgmati K, Theodoridou M, Calver BL, Cumbes B, Nounesis G, Swann K, Lai FA.

Biochem J. 2011 Mar 1;434(2):211-7. doi: 10.1042/BJ20101772. Erratum in: Biochem J. 2011 May 1;435(3):791. Nounesis, Georg [corrected to Nounesis, George].

32.

Structural and thermodynamic characterization of metal ion binding in Streptococcus suis Dpr.

Haikarainen T, Thanassoulas A, Stavros P, Nounesis G, Haataja S, Papageorgiou AC.

J Mol Biol. 2011 Jan 14;405(2):448-60. doi: 10.1016/j.jmb.2010.10.058. Epub 2010 Nov 5.

PMID:
21056572
33.

Arginine end-functionalized poly(L-lysine) dendrigrafts for the stabilization and controlled release of insulin.

Sideratou Z, Sterioti N, Tsiourvas D, Tziveleka LA, Thanassoulas A, Nounesis G, Paleos CM.

J Colloid Interface Sci. 2010 Nov 15;351(2):433-41. doi: 10.1016/j.jcis.2010.07.072. Epub 2010 Aug 4.

PMID:
20797721
34.

Fully integrated monolithic optoelectronic transducer for real-time protein and DNA detection: the NEMOSLAB approach.

Misiakos K, Petrou PS, Kakabakos SE, Yannoukakos D, Contopanagos H, Knoll T, Velten T, DeFazio M, Schiavo L, Passamano M, Stamou D, Nounesis G.

Biosens Bioelectron. 2010 Dec 15;26(4):1528-35. doi: 10.1016/j.bios.2010.07.104. Epub 2010 Aug 3.

PMID:
20729053
35.

Nanoparticle-induced widening of the temperature range of liquid-crystalline blue phases.

Karatairi E, Rozic B, Kutnjak Z, Tzitzios V, Nounesis G, Cordoyiannis G, Thoen J, Glorieux C, Kralj S.

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Apr;81(4 Pt 1):041703. Epub 2010 Apr 26.

PMID:
20481736
36.

Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide.

Thanassoulas A, Nomikos M, Theodoridou M, Yannoukakos D, Mastellos D, Nounesis G.

Biochim Biophys Acta. 2010 Sep;1804(9):1908-16. doi: 10.1016/j.bbapap.2010.04.012. Epub 2010 May 6.

PMID:
20451671
37.

Influence of confinement in controlled-pore glass on the layer spacing of smectic- a liquid crystals.

Cordoyiannis G, Zidansek A, Lahajnar G, Kutnjak Z, Amenitsch H, Nounesis G, Kralj S.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 May;79(5 Pt 1):051703. Epub 2009 May 11.

PMID:
19518470
38.

Characterization of cancer-linked BRCA1-BRCT missense variants and their interaction with phosphoprotein targets.

Drikos I, Nounesis G, Vorgias CE.

Proteins. 2009 Nov 1;77(2):464-76. doi: 10.1002/prot.22460.

PMID:
19452558
39.

Calorimetric study of the interaction of binary DMTAP/DOTAP cationic liposomes with plasmid DNA.

Giatrellis S, Nikolopoulos G, Sideratou Z, Nounesis G.

J Liposome Res. 2009;19(3):220-30. doi: 10.1080/08982100902746596.

PMID:
19255899
40.

The stability of the archaeal HU histone-like DNA-binding protein from Thermoplasma volcanium.

Orfaniotou F, Tzamalis P, Thanassoulas A, Stefanidi E, Zees A, Boutou E, Vlassi M, Nounesis G, Vorgias CE.

Extremophiles. 2009 Jan;13(1):1-10. doi: 10.1007/s00792-008-0190-6. Epub 2008 Sep 26.

PMID:
18818867
41.

Biophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties.

Chroni A, Pyrpassopoulos S, Thanassoulas A, Nounesis G, Zannis VI, Stratikos E.

Biochemistry. 2008 Sep 2;47(35):9071-80. doi: 10.1021/bi800469r. Epub 2008 Aug 9.

42.

Thermal unfolding of human BRCA1 BRCT-domain variants.

Nikolopoulos G, Pyrpassopoulos S, Thanassoulas A, Klimentzou P, Zikos C, Vlassi M, Vorgias CE, Yannoukakos D, Nounesis G.

Biochim Biophys Acta. 2007 Jun;1774(6):772-80. Epub 2007 Apr 6.

PMID:
17493881
43.

Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients.

Konstantopoulou I, Rampias T, Ladopoulou A, Koutsodontis G, Armaou S, Anagnostopoulos T, Nikolopoulos G, Kamakari S, Nounesis G, Stylianakis A, Karanikiotis C, Razis E, Gogas H, Keramopoulos A, Gaki V, Markopoulos C, Skarlos D, Pandis N, Bei T, Arzimanoglou I, Fountzilas G, Yannoukakos D.

Breast Cancer Res Treat. 2008 Feb;107(3):431-41. Epub 2007 Apr 24.

PMID:
17453335
44.

Pretransitional effects near the smectic-A -smectic-C* phase transition of hydrophilic and hydrophobic aerosil networks dispersed in ferroelectric liquid crystals.

Cordoyiannis G, Kralj S, Nounesis G, Kutnjak Z, Zumer S.

Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Feb;75(2 Pt 1):021702. Epub 2007 Feb 6.

PMID:
17358355
45.
46.

Equilibrium heat-induced denaturation of chitinase 40 from Streptomyces thermoviolaceus.

Pyrpassopoulos S, Vlassi M, Tsortos A, Papanikolau Y, Petratos K, Vorgias CE, Nounesis G.

Proteins. 2006 Aug 1;64(2):513-23.

PMID:
16685709
47.

Soft-stiff regime crossover for an aerosil network dispersed in liquid crystals.

Cordoyiannis G, Kralj S, Nounesis G, Zumer S, Kutnjak Z.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Mar;73(3 Pt 1):031707. Epub 2006 Mar 29.

PMID:
16605546
48.

Effect of pH on the structure and stability of Bacillus circulans ssp. alkalophilus phosphoserine aminotransferase: thermodynamic and crystallographic studies.

Kapetaniou EG, Thanassoulas A, Dubnovitsky AP, Nounesis G, Papageorgiou AC.

Proteins. 2006 Jun 1;63(4):742-53.

PMID:
16532449
49.

Interaction of functional dendrimers with multilamellar liposomes: design of a model system for studying drug delivery.

Pantos A, Tsiourvas D, Nounesis G, Paleos CM.

Langmuir. 2005 Aug 2;21(16):7483-90.

PMID:
16042483
50.

Enhanced drug transport from unilamellar to multilamellar liposomes induced by molecular recognition of their lipid membranes.

Pantos A, Tsiourvas D, Paleos CM, Nounesis G.

Langmuir. 2005 Jul 19;21(15):6696-702.

PMID:
16008376

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