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Items: 9

1.

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation.

Brady JP, Farber PJ, Sekhar A, Lin YH, Huang R, Bah A, Nott TJ, Chan HS, Baldwin AJ, Forman-Kay JD, Kay LE.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8194-E8203. doi: 10.1073/pnas.1706197114. Epub 2017 Sep 11.

2.

Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters.

Nott TJ, Craggs TD, Baldwin AJ.

Nat Chem. 2016 Jun;8(6):569-75. doi: 10.1038/nchem.2519. Epub 2016 May 16.

PMID:
27219701
3.

Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains.

Cherry AL, Nott TJ, Kelly G, Rulten SL, Caldecott KW, Smerdon SJ.

DNA Repair (Amst). 2015 Nov;35:116-25. doi: 10.1016/j.dnarep.2015.10.002. Epub 2015 Oct 23.

4.

Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles.

Nott TJ, Petsalaki E, Farber P, Jervis D, Fussner E, Plochowietz A, Craggs TD, Bazett-Jones DP, Pawson T, Forman-Kay JD, Baldwin AJ.

Mol Cell. 2015 Mar 5;57(5):936-947. doi: 10.1016/j.molcel.2015.01.013.

5.

Deciphering arginine methylation: Tudor tells the tale.

Chen C, Nott TJ, Jin J, Pawson T.

Nat Rev Mol Cell Biol. 2011 Sep 14;12(10):629-42. doi: 10.1038/nrm3185. Review.

PMID:
21915143
6.

Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents.

Lougheed KE, Osborne SA, Saxty B, Whalley D, Chapman T, Bouloc N, Chugh J, Nott TJ, Patel D, Spivey VL, Kettleborough CA, Bryans JS, Taylor DL, Smerdon SJ, Buxton RS.

Tuberculosis (Edinb). 2011 Jul;91(4):277-86. doi: 10.1016/j.tube.2011.03.005. Epub 2011 Apr 11.

7.

Structural and functional analysis of phosphothreonine-dependent FHA domain interactions.

Pennell S, Westcott S, Ortiz-Lombardía M, Patel D, Li J, Nott TJ, Mohammed D, Buxton RS, Yaffe MB, Verma C, Smerdon SJ.

Structure. 2010 Dec 8;18(12):1587-95. doi: 10.1016/j.str.2010.09.014.

8.

An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis.

Nott TJ, Kelly G, Stach L, Li J, Westcott S, Patel D, Hunt DM, Howell S, Buxton RS, O'Hare HM, Smerdon SJ.

Sci Signal. 2009 Mar 24;2(63):ra12. doi: 10.1126/scisignal.2000212.

9.

Structure and regulation of the human Nek2 centrosomal kinase.

Rellos P, Ivins FJ, Baxter JE, Pike A, Nott TJ, Parkinson DM, Das S, Howell S, Fedorov O, Shen QY, Fry AM, Knapp S, Smerdon SJ.

J Biol Chem. 2007 Mar 2;282(9):6833-42. Epub 2006 Dec 31.

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