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Manufacture of endothelial colony-forming progenitor cells from steady-state peripheral blood leukapheresis using pooled human platelet lysate.

Siegel G, Fleck E, Elser S, Hermanutz-Klein U, Waidmann M, Northoff H, Seifried E, Schäfer R.

Transfusion. 2018 May;58(5):1132-1142. doi: 10.1111/trf.14541. Epub 2018 Feb 22.


Aerobic exercise inhibits acute lung injury: from mouse to human evidence Exercise reduced lung injury markers in mouse and in cells.

Rigonato-Oliveira NC, Mackenzie B, Bachi ALL, Oliveira-Junior MC, Santos-Dias A, Brandao-Rangel MAR, Delle H, Costa-Guimaraes T, Damaceno-Rodrigues NR, Dulley NR, Benetti MA, Malfitano C, de Angelis C, Albertini R, Oliveira APL, Abbasi A, Northoff H, Vieira RP.

Exerc Immunol Rev. 2018;24:36-44.


QCM-D surpassing clinical standard for the dose administration of new oral anticoagulant in the patient of coagulation disorders.

Hussain M, Wendel HP, Schmidt K, Langer E, Körber MK, Faul O, Northoff H, von Heymann C, Gehring FK.

Biosens Bioelectron. 2018 May 1;104:15-20. doi: 10.1016/j.bios.2017.12.043. Epub 2017 Dec 27.


Good Feasibility of the New German Blood Donor Questionnaire.

Houareau C, Deitenbeck R, Sümnig A, Moeller A, Saadé C, Stötzer F, Heiden M, Northoff H, Offergeld R.

Transfus Med Hemother. 2017 Aug;44(4):232-239. doi: 10.1159/000477942. Epub 2017 Jul 14.


Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.

Pace S, Pergola C, Dehm F, Rossi A, Gerstmeier J, Troisi F, Pein H, Schaible AM, Weinigel C, Rummler S, Northoff H, Laufer S, Maier TJ, Rådmark O, Samuelsson B, Koeberle A, Sautebin L, Werz O.

J Clin Invest. 2017 Aug 1;127(8):3167-3176. doi: 10.1172/JCI92885. Epub 2017 Jul 24.


Defined Structure-Activity Relationships of Boswellic Acids Determine Modulation of Ca2+ Mobilization and Aggregation of Human Platelets by Boswellia serrata Extracts.

Siemoneit U, Tausch L, Poeckel D, Paul M, Northoff H, Koeberle A, Jauch J, Werz O.

Planta Med. 2017 Aug;83(12-13):1020-1027. doi: 10.1055/s-0043-107884. Epub 2017 Apr 12.


Sex-specific variation in signaling pathways and gene expression patterns in human leukocytes in response to endotoxin and exercise.

Abbasi A, de Paula Vieira R, Bischof F, Walter M, Movassaghi M, Berchtold NC, Niess AM, Cotman CW, Northoff H.

J Neuroinflammation. 2016 Nov 10;13(1):289.


Aerobic Exercise Reduces Asthma Phenotype by Modulation of the Leukotriene Pathway.

Alberca-Custódio RW, Greiffo FR, MacKenzie B, Oliveira-Junior MC, Andrade-Sousa AS, Graudenz GS, Santos AB, Damaceno-Rodrigues NR, Castro-Faria-Neto HC, Arantes-Costa FM, Martins Mde A, Abbasi A, Lin CJ, Idzko M, Ligeiro Oliveira AP, Northoff H, Vieira RP.

Front Immunol. 2016 Jun 14;7:237. doi: 10.3389/fimmu.2016.00237. eCollection 2016.


Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance.

Kömpf D, Held J, Müller SF, Drechsel HR, Tschan SC, Northoff H, Mordmüller B, Gehring FK.

Malar J. 2016 Jun 13;15:317. doi: 10.1186/s12936-016-1374-7.


Utilisation of Quartz Crystal Microbalance Sensors with Dissipation (QCM-D) for a Clauss Fibrinogen Assay in Comparison with Common Coagulation Reference Methods.

Oberfrank S, Drechsel H, Sinn S, Northoff H, Gehring FK.

Sensors (Basel). 2016 Feb 24;16(3):282. doi: 10.3390/s16030282.


Effect of bisphosphonates on macrophagic THP-1 cell survival in bisphosphonate-related osteonecrosis of the jaw (BRONJ).

Hoefert S, Sade Hoefert C, Munz A, Schmitz I, Grimm M, Yuan A, Northoff H, Reinert S, Alexander D.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Mar;121(3):222-32. doi: 10.1016/j.oooo.2015.10.008. Epub 2015 Oct 22.


Detection of HIT antibody dependent platelet aggregation using novel surface imprinting approach.

Hussain M, Northoff H, Gehring FK.

Talanta. 2016 Jan 15;147:1-7. doi: 10.1016/j.talanta.2015.09.027. Epub 2015 Sep 14.


Altered macrophagic THP-1 cell phagocytosis and migration in bisphosphonate-related osteonecrosis of the jaw (BRONJ).

Hoefert S, Sade Hoefert C, Munz A, Northoff H, Yuan A, Reichenmiller K, Reinert S, Grimm M.

Clin Oral Investig. 2016 Jun;20(5):1043-54. doi: 10.1007/s00784-015-1584-3. Epub 2015 Sep 9.


Progesterone rapidly down-regulates the biosynthesis of 5-lipoxygenase products in human primary monocytes.

Pergola C, Schaible AM, Nikels F, Dodt G, Northoff H, Werz O.

Pharmacol Res. 2015 Apr;94:42-50. doi: 10.1016/j.phrs.2015.01.007. Epub 2015 Feb 11.


QCM-D providing new horizon in the domain of sensitivity range and information for haemostasis of human plasma.

Hussain M, Northoff H, Gehring FK.

Biosens Bioelectron. 2015 Apr 15;66:579-84. doi: 10.1016/j.bios.2014.12.003. Epub 2014 Dec 3.


Zoledronate but not denosumab suppresses macrophagic differentiation of THP-1 cells. An aetiologic model of bisphosphonate-related osteonecrosis of the jaw (BRONJ).

Hoefert S, Hoefert CS, Albert M, Munz A, Grimm M, Northoff H, Reinert S, Alexander D.

Clin Oral Investig. 2015 Jul;19(6):1307-18. doi: 10.1007/s00784-014-1358-3. Epub 2014 Nov 21.


Exercise immunology meets MiRNAs.

Makarova JA, Maltseva DV, Galatenko VV, Abbasi A, Maximenko DG, Grigoriev AI, Tonevitsky AG, Northoff H.

Exerc Immunol Rev. 2014;20:135-64. Review.


Exhaustive exercise modifies different gene expression profiles and pathways in LPS-stimulated and un-stimulated whole blood cultures.

Abbasi A, Hauth M, Walter M, Hudemann J, Wank V, Niess AM, Northoff H.

Brain Behav Immun. 2014 Jul;39:130-41. doi: 10.1016/j.bbi.2013.10.023. Epub 2013 Oct 26.


Dynamically regulated miRNA-mRNA networks revealed by exercise.

Tonevitsky AG, Maltseva DV, Abbasi A, Samatov TR, Sakharov DA, Shkurnikov MU, Lebedev AE, Galatenko VV, Grigoriev AI, Northoff H.

BMC Physiol. 2013 Jun 7;13:9. doi: 10.1186/1472-6793-13-9.


Changes in spontaneous and LPS-induced ex vivo cytokine production and mRNA expression in male and female athletes following prolonged exhaustive exercise.

Abbasi A, Fehrenbach E, Hauth M, Walter M, Hudemann J, Wank V, Niess AM, Northoff H.

Exerc Immunol Rev. 2013;19:8-28.


High capacity for leukotriene biosynthesis in peripheral blood during pregnancy.

Schaible AM, Koeberle A, Northoff H, Lawrenz B, Weinigel C, Barz D, Werz O, Pergola C.

Prostaglandins Leukot Essent Fatty Acids. 2013 Sep;89(4):245-55. doi: 10.1016/j.plefa.2013.06.004. Epub 2013 Jul 16.


Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells.

Siegel G, Kluba T, Hermanutz-Klein U, Bieback K, Northoff H, Schäfer R.

BMC Med. 2013 Jun 11;11:146. doi: 10.1186/1741-7015-11-146.


Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer.

Ahmad SS, Glatzle J, Bajaeifer K, Bühler S, Lehmann T, Königsrainer I, Vollmer JP, Sipos B, Ahmad SS, Northoff H, Königsrainer A, Zieker D.

Int J Oncol. 2013 Aug;43(2):586-90. doi: 10.3892/ijo.2013.1971. Epub 2013 May 31.


Induction of tumor stem cell differentiation--novel strategy to overcome therapy resistance in gastric cancer.

Zieker D, Bühler S, Ustündag Z, Königsrainer I, Manncke S, Bajaeifer K, Vollmer J, Fend F, Northoff H, Königsrainer A, Glatzle J.

Langenbecks Arch Surg. 2013 Apr;398(4):603-8. doi: 10.1007/s00423-013-1058-5. Epub 2013 Feb 15.


Mesenchymal stromal/stem cells markers in the human bone marrow.

Rasini V, Dominici M, Kluba T, Siegel G, Lusenti G, Northoff H, Horwitz EM, Schäfer R.

Cytotherapy. 2013 Mar;15(3):292-306. doi: 10.1016/j.jcyt.2012.11.009. Epub 2013 Jan 9.


Lactate influences the gene expression profile of human mesenchymal stem cells (hMSC) in a dose dependant manner.

Schneider CC, Ateschrang A, Königsrainer I, Glatzle J, Bühler S, Schaefer R, Northoff H, Königsrainer A, Zieker D.

Cell Physiol Biochem. 2012;30(6):1547-56. doi: 10.1159/000343342. Epub 2012 Dec 10.


MSH2 and CXCR4 involvement in malignant VIPoma.

Müller S, Kupka S, Königsrainer I, Northoff H, Sotlar K, Bock T, Kandolf R, Traub F, Königsrainer A, Zieker D.

World J Surg Oncol. 2012 Dec 11;10:264. doi: 10.1186/1477-7819-10-264.


Impact of endotoxin exposure after exhausting exercise on the immune system in solid organ transplant recipients.

Königsrainer I, Löffler M, Bühler S, Walter M, Schafbuch L, Beckert S, Glatzle J, Horvath P, Northoff H, Nadalin S, Königsrainer A, Zieker D.

Exerc Immunol Rev. 2012;18:177-83.


A novel C(28)-hydroxylated lupeolic acid suppresses the biosynthesis of eicosanoids through inhibition of cytosolic phospholipase A(2).

Verhoff M, Seitz S, Northoff H, Jauch J, Schaible AM, Werz O.

Biochem Pharmacol. 2012 Sep 1;84(5):681-91. doi: 10.1016/j.bcp.2012.06.016. Epub 2012 Jun 23.


Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.

Bauer J, Kuehnl S, Rollinger JM, Scherer O, Northoff H, Stuppner H, Werz O, Koeberle A.

J Pharmacol Exp Ther. 2012 Jul;342(1):169-76. doi: 10.1124/jpet.112.193847. Epub 2012 Apr 16.


Bone marrow-derived human mesenchymal stem cells express cardiomyogenic proteins but do not exhibit functional cardiomyogenic differentiation potential.

Siegel G, Krause P, Wöhrle S, Nowak P, Ayturan M, Kluba T, Brehm BR, Neumeister B, Köhler D, Rosenberger P, Just L, Northoff H, Schäfer R.

Stem Cells Dev. 2012 Sep 1;21(13):2457-70. doi: 10.1089/scd.2011.0626. Epub 2012 Mar 13.


NCO-sP(EO-stat-PO) coatings on gold sensors--a QCM study of hemocompatibility.

Sinn S, Eichler M, Müller L, Bünger D, Groll J, Ziemer G, Rupp F, Northoff H, Geis-Gerstorfer J, Gehring FK, Wendel HP.

Sensors (Basel). 2011;11(5):5253-69. doi: 10.3390/s110505253. Epub 2011 May 13.


Boswellic acids from frankincense inhibit lipopolysaccharide functionality through direct molecular interference.

Henkel A, Kather N, Mönch B, Northoff H, Jauch J, Werz O.

Biochem Pharmacol. 2012 Jan 1;83(1):115-21. doi: 10.1016/j.bcp.2011.09.026. Epub 2011 Oct 5.


PK11195, a specific ligand of the peripheral benzodiazepine receptor, may protect pancreatic beta-cells from cytokine-induced cell death.

Klaffschenkel RA, Waidmann M, Northoff H, Mahmoud AA, Lembert N.

Artif Cells Blood Substit Immobil Biotechnol. 2012 Feb;40(1-2):56-61. doi: 10.3109/10731199.2011.585617. Epub 2011 Aug 2.


On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficacy in vivo.

Pergola C, Jazzar B, Rossi A, Northoff H, Hamburger M, Sautebin L, Werz O.

Br J Pharmacol. 2012 Feb;165(3):765-76. doi: 10.1111/j.1476-5381.2011.01605.x.


Passing the anaerobic threshold is associated with substantial changes in the gene expression profile in white blood cells.

Sakharov DA, Maltseva DV, Riabenko EA, Shkurnikov MU, Northoff H, Tonevitsky AG, Grigoriev AI.

Eur J Appl Physiol. 2012 Mar;112(3):963-72. doi: 10.1007/s00421-011-2048-3. Epub 2011 Jun 30.


Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes.

Pergola C, Rogge A, Dodt G, Northoff H, Weinigel C, Barz D, Rådmark O, Sautebin L, Werz O.

FASEB J. 2011 Oct;25(10):3377-87. doi: 10.1096/fj.11-182758. Epub 2011 Jun 21.


Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo.

Koeberle A, Rossi A, Bauer J, Dehm F, Verotta L, Northoff H, Sautebin L, Werz O.

Front Pharmacol. 2011 Feb 18;2:7. doi: 10.3389/fphar.2011.00007. eCollection 2011.


Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1.

Greiner C, Zettl H, Koeberle A, Pergola C, Northoff H, Schubert-Zsilavecz M, Werz O.

Bioorg Med Chem. 2011 Jun 1;19(11):3394-401. doi: 10.1016/j.bmc.2011.04.034. Epub 2011 Apr 22.


Cinnamyl-3,4-dihydroxy-α-cyanocinnamate is a potent inhibitor of 5-lipoxygenase.

Pergola C, Jazzar B, Rossi A, Buehring U, Luderer S, Dehm F, Northoff H, Sautebin L, Werz O.

J Pharmacol Exp Ther. 2011 Jul;338(1):205-13. doi: 10.1124/jpet.111.180794. Epub 2011 Mar 29.


Killer cell immunoglobulin-like receptors and exercise.

Maltseva DV, Sakharov DA, Tonevitsky EA, Northoff H, Tonevitsky AG.

Exerc Immunol Rev. 2011;17:150-63. Review.


Position statement. Part one: Immune function and exercise.

Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P.

Exerc Immunol Rev. 2011;17:6-63. Review.


Expression of blood group genes by mesenchymal stem cells.

Schäfer R, Schnaidt M, Klaffschenkel RA, Siegel G, Schüle M, Rädlein MA, Hermanutz-Klein U, Ayturan M, Buadze M, Gassner C, Danielyan L, Kluba T, Northoff H, Flegel WA.

Br J Haematol. 2011 May;153(4):520-8. doi: 10.1111/j.1365-2141.2011.08652.x. Epub 2011 Mar 21.


Wound fluid lactate concentration: a helpful marker for diagnosing soft-tissue infection in diabetic foot ulcers? Preliminary findings.

Löffler M, Zieker D, Weinreich J, Löb S, Königsrainer I, Symons S, Bühler S, Königsrainer A, Northoff H, Beckert S.

Diabet Med. 2011 Feb;28(2):175-8. doi: 10.1111/j.1464-5491.2010.03123.x.


Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo.

Bauer J, Koeberle A, Dehm F, Pollastro F, Appendino G, Northoff H, Rossi A, Sautebin L, Werz O.

Biochem Pharmacol. 2011 Jan 15;81(2):259-68. doi: 10.1016/j.bcp.2010.09.025. Epub 2010 Oct 8.


Platelet aggregation monitoring with a newly developed quartz crystal microbalance system as an alternative to optical platelet aggregometry.

Sinn S, Müller L, Drechsel H, Wandel M, Northoff H, Ziemer G, Wendel HP, Gehring FK.

Analyst. 2010 Nov;135(11):2930-8. doi: 10.1039/c0an00474j. Epub 2010 Sep 29.


Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense.

Siemoneit U, Koeberle A, Rossi A, Dehm F, Verhoff M, Reckel S, Maier TJ, Jauch J, Northoff H, Bernhard F, Doetsch V, Sautebin L, Werz O.

Br J Pharmacol. 2011 Jan;162(1):147-62. doi: 10.1111/j.1476-5381.2010.01020.x.


Influence of exhaustive exercise on the immune system in solid organ transplant recipients.

Königsrainer I, Zieker D, Löffler M, Bühler S, Walter M, Beckert S, Glatzle J, Northoff H, Nadalin S, Königsrainer A.

Exerc Immunol Rev. 2010;16:184-93.


Circadian expression of clock- and tumor suppressor genes in human oral mucosa.

Zieker D, Jenne I, Koenigsrainer I, Zdichavsky M, Nieselt K, Buck K, Zieker J, Beckert S, Glatzle J, Spanagel R, Koenigsrainer A, Northoff H, Loeffler M.

Cell Physiol Biochem. 2010;26(2):155-66. doi: 10.1159/000320547. Epub 2010 Aug 24.

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