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Items: 12


New Horizons in Advocacy Engaged Physical Sciences and Oncology Research.

Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM.

Trends Cancer. 2018 Apr;4(4):260-264. doi: 10.1016/j.trecan.2018.02.002. Epub 2018 Mar 15. Review.


Tissue Force Programs Cell Fate and Tumor Aggression.

Northey JJ, Przybyla L, Weaver VM.

Cancer Discov. 2017 Nov;7(11):1224-1237. doi: 10.1158/2159-8290.CD-16-0733. Epub 2017 Oct 16. Review.


PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.

Andrzejewski S, Klimcakova E, Johnson RM, Tabariès S, Annis MG, McGuirk S, Northey JJ, Chénard V, Sriram U, Papadopoli DJ, Siegel PM, St-Pierre J.

Cell Metab. 2017 Nov 7;26(5):778-787.e5. doi: 10.1016/j.cmet.2017.09.006. Epub 2017 Oct 5.


The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer.

He Y, Northey JJ, Pelletier A, Kos Z, Meunier L, Haibe-Kains B, Mes-Masson AM, Côté JF, Siegel PM, Lamarche-Vane N.

Oncogene. 2017 Jun 15;36(24):3490-3503. doi: 10.1038/onc.2016.492. Epub 2017 Jan 30.


Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion.

Cyr-Depauw C, Northey JJ, Tabariès S, Annis MG, Dong Z, Cory S, Hallett M, Rennhack JP, Andrechek ER, Siegel PM.

Mol Cell Biol. 2016 May 2;36(10):1509-25. doi: 10.1128/MCB.00600-15. Print 2016 May 15.


Fighting the force: Potential of homeobox genes for tumor microenvironment regulation.

Northcott JM, Northey JJ, Barnes JM, Weaver VM.

Biochim Biophys Acta. 2015 Apr;1855(2):248-53. doi: 10.1016/j.bbcan.2015.03.004. Epub 2015 Mar 24. Review.


A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells.

Ngan E, Northey JJ, Brown CM, Ursini-Siegel J, Siegel PM.

J Cell Sci. 2013 May 1;126(Pt 9):1981-91. doi: 10.1242/jcs.118315. Epub 2013 Feb 27.


Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion, and metastasis.

Northey JJ, Dong Z, Ngan E, Kaplan A, Hardy WR, Pawson T, Siegel PM.

J Biol Chem. 2013 Feb 15;288(7):5210-22. doi: 10.1074/jbc.M112.424804. Epub 2012 Dec 31.


CdGAP is required for transforming growth factor β- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

He Y, Northey JJ, Primeau M, Machado RD, Trembath R, Siegel PM, Lamarche-Vane N.

Oncogene. 2011 Mar 3;30(9):1032-45. doi: 10.1038/onc.2010.477. Epub 2010 Nov 1.


The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.

Roovers K, Wagner S, Storbeck CJ, O'Reilly P, Lo V, Northey JJ, Chmielecki J, Muller WJ, Siegel PM, Sabourin LA.

Oncogene. 2009 Aug 6;28(31):2839-48. doi: 10.1038/onc.2009.146. Epub 2009 Jun 15.


Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

Northey JJ, Chmielecki J, Ngan E, Russo C, Annis MG, Muller WJ, Siegel PM.

Mol Cell Biol. 2008 May;28(10):3162-76. doi: 10.1128/MCB.01734-07. Epub 2008 Mar 10.


Targeting aberrant TGF-beta signaling in pre-clinical models of cancer.

Mourskaia AA, Northey JJ, Siegel PM.

Anticancer Agents Med Chem. 2007 Sep;7(5):504-14. Review.


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