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Items: 38

1.

Functional analysis of deubiquitylating enzymes in tumorigenesis and development.

Cheng J, Guo J, North BJ, Wang B, Cui CP, Li H, Tao K, Zhang L, Wei W.

Biochim Biophys Acta Rev Cancer. 2019 Aug 23;1872(2):188312. doi: 10.1016/j.bbcan.2019.188312. [Epub ahead of print] Review.

PMID:
31449841
2.

The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection.

Cabrera JR, Manivanh R, North BJ, Leib DA.

MBio. 2019 Mar 5;10(2). pii: e02567-18. doi: 10.1128/mBio.02567-18.

3.

The US11 Gene of Herpes Simplex Virus 1 Promotes Neuroinvasion and Periocular Replication following Corneal Infection.

Charron AJ, Ward SL, North BJ, Ceron S, Leib DA.

J Virol. 2019 Apr 17;93(9). pii: e02246-18. doi: 10.1128/JVI.02246-18. Print 2019 May 1.

PMID:
30760571
4.

The STING agonist 5,6-dimethylxanthenone-4-acetic acid (DMXAA) stimulates an antiviral state and protects mice against herpes simplex virus-induced neurological disease.

Cerón S, North BJ, Taylor SA, Leib DA.

Virology. 2019 Mar;529:23-28. doi: 10.1016/j.virol.2019.01.006. Epub 2019 Jan 6.

PMID:
30648635
5.

The emerging role for Cullin 4 family of E3 ligases in tumorigenesis.

Cheng J, Guo J, North BJ, Tao K, Zhou P, Wei W.

Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):138-159. doi: 10.1016/j.bbcan.2018.11.007. Epub 2018 Dec 30. Review.

PMID:
30602127
6.

SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivation.

Ma Y, Cui D, Xiong X, Inuzuka H, Wei W, Sun Y, North BJ, Zhao Y.

Mol Oncol. 2019 Feb;13(2):307-321. doi: 10.1002/1878-0261.12403. Epub 2018 Dec 3.

7.

The emerging roles of protein homeostasis-governing pathways in Alzheimer's disease.

Cheng J, North BJ, Zhang T, Dai X, Tao K, Guo J, Wei W.

Aging Cell. 2018 Oct;17(5):e12801. doi: 10.1111/acel.12801. Epub 2018 Jul 10. Review.

8.

SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation.

Ci Y, Li X, Chen M, Zhong J, North BJ, Inuzuka H, He X, Li Y, Guo J, Dai X.

Protein Cell. 2018 Oct;9(10):879-889. doi: 10.1007/s13238-018-0510-2. Epub 2018 Mar 1.

9.

Functional analysis of Cullin 3 E3 ligases in tumorigenesis.

Cheng J, Guo J, Wang Z, North BJ, Tao K, Dai X, Wei W.

Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):11-28. doi: 10.1016/j.bbcan.2017.11.001. Epub 2017 Nov 8. Review.

PMID:
29128526
10.

Isolation, Purification, and Culture of Primary Murine Sensory Neurons.

Katzenell S, Cabrera JR, North BJ, Leib DA.

Methods Mol Biol. 2017;1656:229-251. doi: 10.1007/978-1-4939-7237-1_15.

11.

Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.

Guo J, Cheng J, North BJ, Wei W.

Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):341-358. doi: 10.1016/j.bbcan.2017.07.001. Epub 2017 Jul 8. Review.

12.

Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6.

Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, North BJ, Huo J, Zhang J.

Oncotarget. 2017 Jul 18;8(29):47890-47901. doi: 10.18632/oncotarget.18141.

13.

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W.

Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10.

14.

Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor.

North BJ, Almeciga-Pinto I, Tamang D, Yang M, Jones SS, Quayle SN.

PLoS One. 2017 Mar 6;12(3):e0173507. doi: 10.1371/journal.pone.0173507. eCollection 2017.

15.

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.

Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W.

Sci Signal. 2017 Feb 14;10(466). pii: eaai8026. doi: 10.1126/scisignal.aai8026.

16.

The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.

Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.

Sci Signal. 2017 Jan 3;10(460). pii: eaah4117. doi: 10.1126/scisignal.aah4117.

17.

Correction to: Isolation, Purification, and Culture of Primary Murine Sensory Neurons.

Katzenell S, Cabrera JR, North BJ, Leib DA.

Methods Mol Biol. 2017;1656:E3. doi: 10.1007/978-1-4939-7237-1_19.

PMID:
30350167
18.

Smurf1 regulation of DAB2IP controls cell proliferation and migration.

Li X, Dai X, Wan L, Inuzuka H, Sun L, North BJ.

Oncotarget. 2016 May 3;7(18):26057-69. doi: 10.18632/oncotarget.8424.

19.

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

Rumpf T, Schiedel M, Karaman B, Roessler C, North BJ, Lehotzky A, Oláh J, Ladwein KI, Schmidtkunz K, Gajer M, Pannek M, Steegborn C, Sinclair DA, Gerhardt S, Ovádi J, Schutkowski M, Sippl W, Einsle O, Jung M.

Nat Commun. 2015 Feb 12;6:6263. doi: 10.1038/ncomms7263.

20.

SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination.

Wu X, Fukushima H, North BJ, Nagaoka Y, Nagashima K, Deng F, Okabe K, Inuzuka H, Wei W.

Oncotarget. 2014 Jun 30;5(12):4211-21.

21.

Negative regulation of DAB2IP by Akt and SCFFbw7 pathways.

Dai X, North BJ, Inuzuka H.

Oncotarget. 2014 May 30;5(10):3307-15.

22.

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

North BJ, Rosenberg MA, Jeganathan KB, Hafner AV, Michan S, Dai J, Baker DJ, Cen Y, Wu LE, Sauve AA, van Deursen JM, Rosenzweig A, Sinclair DA.

EMBO J. 2014 Jul 1;33(13):1438-53. doi: 10.15252/embj.201386907. Epub 2014 May 12.

23.

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

Bonezzi K, Belotti D, North BJ, Ghilardi C, Borsotti P, Resovi A, Ubezio P, Riva A, Giavazzi R, Verdin E, Taraboletti G.

Neoplasia. 2012 Sep;14(9):846-54.

24.

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA.

Cell Metab. 2012 May 2;15(5):675-90. doi: 10.1016/j.cmet.2012.04.003.

25.

The intersection between aging and cardiovascular disease.

North BJ, Sinclair DA.

Circ Res. 2012 Apr 13;110(8):1097-108. doi: 10.1161/CIRCRESAHA.111.246876. Review.

26.

Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.

Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26.

27.
28.

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.

Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E.

J Biol Chem. 2007 Nov 16;282(46):33583-92. Epub 2007 Aug 22.

29.

Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.

North BJ, Verdin E.

J Biol Chem. 2007 Jul 6;282(27):19546-55. Epub 2007 May 8.

30.

Sirtuins: a conserved key unlocking AceCS activity.

North BJ, Sinclair DA.

Trends Biochem Sci. 2007 Jan;32(1):1-4. Epub 2006 Dec 1.

31.

Preparation of enzymatically active recombinant class III protein deacetylases.

North BJ, Schwer B, Ahuja N, Marshall B, Verdin E.

Methods. 2005 Aug;36(4):338-45. Review.

PMID:
16091304
32.

Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.

Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V.

FASEB J. 2005 Jun;19(8):966-8. Epub 2005 Mar 16.

PMID:
15772115
33.

SIRT1 regulates HIV transcription via Tat deacetylation.

Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M.

PLoS Biol. 2005 Feb;3(2):e41. Epub 2005 Feb 8.

34.

Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues.

Waltregny D, De Leval L, Glénisson W, Ly Tran S, North BJ, Bellahcène A, Weidle U, Verdin E, Castronovo V.

Am J Pathol. 2004 Aug;165(2):553-64.

35.

Sirtuins: Sir2-related NAD-dependent protein deacetylases.

North BJ, Verdin E.

Genome Biol. 2004;5(5):224. Epub 2004 Apr 28. Review.

36.

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.

North BJ, Marshall BL, Borra MT, Denu JM, Verdin E.

Mol Cell. 2003 Feb;11(2):437-44.

37.

N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor.

Verzi MP, Anderson JP, Dodou E, Kelly KK, Greene SB, North BJ, Cripps RM, Black BL.

Dev Biol. 2002 Sep 1;249(1):174-90.

38.

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.

Schwer B, North BJ, Frye RA, Ott M, Verdin E.

J Cell Biol. 2002 Aug 19;158(4):647-57. Epub 2002 Aug 19.

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