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Items: 1 to 50 of 143


Response of triploid Atlantic salmon (Salmo salar) to commercial vaccines.

Chalmers L, Migaud H, Adams A, Vera LM, McStay E, North B, Mitchell C, Taylor JF.

Fish Shellfish Immunol. 2019 Dec 23;97:624-636. doi: 10.1016/j.fsi.2019.12.070. [Epub ahead of print]


Predicting shockwave lithotripsy outcome for urolithiasis using clinical and stone computed tomography texture analysis variables.

Cui HW, Silva MD, Mills AW, North BV, Turney BW.

Sci Rep. 2019 Oct 11;9(1):14674. doi: 10.1038/s41598-019-51026-x.


Functional analysis of deubiquitylating enzymes in tumorigenesis and development.

Cheng J, Guo J, North BJ, Wang B, Cui CP, Li H, Tao K, Zhang L, Wei W.

Biochim Biophys Acta Rev Cancer. 2019 Dec;1872(2):188312. doi: 10.1016/j.bbcan.2019.188312. Epub 2019 Aug 23. Review.


Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort.

Organ LA, Duggan AR, Oballa E, Taggart SC, Simpson JK, Kang'ombe AR, Braybrooke R, Molyneaux PL, North B, Karkera Y, Leeming DJ, Karsdal MA, Nanthakumar CB, Fahy WA, Marshall RP, Jenkins RG, Maher TM.

Respir Res. 2019 Jul 12;20(1):148. doi: 10.1186/s12931-019-1118-7.


A new pragmatic design for dose escalation in phase 1 clinical trials using an adaptive continual reassessment method.

North B, Kocher HM, Sasieni P.

BMC Cancer. 2019 Jun 26;19(1):632. doi: 10.1186/s12885-019-5801-3.


The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection.

Cabrera JR, Manivanh R, North BJ, Leib DA.

mBio. 2019 Mar 5;10(2). pii: e02567-18. doi: 10.1128/mBio.02567-18.


The US11 Gene of Herpes Simplex Virus 1 Promotes Neuroinvasion and Periocular Replication following Corneal Infection.

Charron AJ, Ward SL, North BJ, Ceron S, Leib DA.

J Virol. 2019 Apr 17;93(9). pii: e02246-18. doi: 10.1128/JVI.02246-18. Print 2019 May 1.


The STING agonist 5,6-dimethylxanthenone-4-acetic acid (DMXAA) stimulates an antiviral state and protects mice against herpes simplex virus-induced neurological disease.

Cerón S, North BJ, Taylor SA, Leib DA.

Virology. 2019 Mar;529:23-28. doi: 10.1016/j.virol.2019.01.006. Epub 2019 Jan 6.


The emerging role for Cullin 4 family of E3 ligases in tumorigenesis.

Cheng J, Guo J, North BJ, Tao K, Zhou P, Wei W.

Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):138-159. doi: 10.1016/j.bbcan.2018.11.007. Epub 2018 Dec 30. Review.


SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivation.

Ma Y, Cui D, Xiong X, Inuzuka H, Wei W, Sun Y, North BJ, Zhao Y.

Mol Oncol. 2019 Feb;13(2):307-321. doi: 10.1002/1878-0261.12403. Epub 2018 Dec 3.


The emerging roles of protein homeostasis-governing pathways in Alzheimer's disease.

Cheng J, North BJ, Zhang T, Dai X, Tao K, Guo J, Wei W.

Aging Cell. 2018 Oct;17(5):e12801. doi: 10.1111/acel.12801. Epub 2018 Jul 10. Review.


Should reporting of peri-neural invasion and extra prostatic extension be mandatory in prostate cancer biopsies? correlation with outcome in biopsy cases treated conservatively.

Ahmad AS, Parameshwaran V, Beltran L, Fisher G, North BV, Greenberg D, Soosay G, Møller H, Scardino P, Cuzick J, Berney DM; Transatlantic Prostate Group.

Oncotarget. 2018 Apr 17;9(29):20555-20562. doi: 10.18632/oncotarget.24994. eCollection 2018 Apr 17.


SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation.

Ci Y, Li X, Chen M, Zhong J, North BJ, Inuzuka H, He X, Li Y, Guo J, Dai X.

Protein Cell. 2018 Oct;9(10):879-889. doi: 10.1007/s13238-018-0510-2. Epub 2018 Mar 1.


Functional analysis of Cullin 3 E3 ligases in tumorigenesis.

Cheng J, Guo J, Wang Z, North BJ, Tao K, Dai X, Wei W.

Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):11-28. doi: 10.1016/j.bbcan.2017.11.001. Epub 2017 Nov 8. Review.


Isolation, Purification, and Culture of Primary Murine Sensory Neurons.

Katzenell S, Cabrera JR, North BJ, Leib DA.

Methods Mol Biol. 2017;1656:229-251. doi: 10.1007/978-1-4939-7237-1_15. Erratum in: Methods Mol Biol. 2017;1656:E3.


Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer.

Stankiewicz E, Mao X, Mangham DC, Xu L, Yeste-Velasco M, Fisher G, North B, Chaplin T, Young B, Wang Y, Kaur Bansal J, Kudahetti S, Spencer L, Foster CS, Møller H, Scardino P, Oliver RT, Shamash J, Cuzick J, Cooper CS, Berney DM, Lu YJ.

Sci Rep. 2017 Jul 11;7(1):5124. doi: 10.1038/s41598-017-05209-z.


Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.

Guo J, Cheng J, North BJ, Wei W.

Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):341-358. doi: 10.1016/j.bbcan.2017.07.001. Epub 2017 Jul 8. Review.


Maternal Antiviral Immunoglobulin Accumulates in Neural Tissue of Neonates To Prevent HSV Neurological Disease.

Jiang Y, Patel CD, Manivanh R, North B, Backes IM, Posner DA, Gilli F, Pachner AR, Nguyen LN, Leib DA.

mBio. 2017 Jul 5;8(4). pii: e00678-17. doi: 10.1128/mBio.00678-17.


Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6.

Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, North BJ, Huo J, Zhang J.

Oncotarget. 2017 Jul 18;8(29):47890-47901. doi: 10.18632/oncotarget.18141.


TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W.

Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10.


Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor.

North BJ, Almeciga-Pinto I, Tamang D, Yang M, Jones SS, Quayle SN.

PLoS One. 2017 Mar 6;12(3):e0173507. doi: 10.1371/journal.pone.0173507. eCollection 2017.


Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.

Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W.

Sci Signal. 2017 Feb 14;10(466). pii: eaai8026. doi: 10.1126/scisignal.aai8026.


The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.

Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.

Sci Signal. 2017 Jan 3;10(460). pii: eaah4117. doi: 10.1126/scisignal.aah4117.


Correction to: Isolation, Purification, and Culture of Primary Murine Sensory Neurons.

Katzenell S, Cabrera JR, North BJ, Leib DA.

Methods Mol Biol. 2017;1656:E3. doi: 10.1007/978-1-4939-7237-1_19.


A comparison of the response of diploid and triploid Atlantic salmon (Salmo salar) siblings to a commercial furunculosis vaccine and subsequent experimental infection with Aeromonas salmonicida.

Chalmers L, Thompson KD, Taylor JF, Black S, Migaud H, North B, Adams A.

Fish Shellfish Immunol. 2016 Oct;57:301-308. doi: 10.1016/j.fsi.2016.08.049. Epub 2016 Aug 25.


Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency.

Rosato PC, Katzenell S, Pesola JM, North B, Coen DM, Leib DA.

Virology. 2016 Oct;497:323-327. doi: 10.1016/j.virol.2016.06.016. Epub 2016 Aug 10.


Corrigendum to "A novel and validated prognostic index in hepatocellular carcinoma: The Inflammation Based Index (IBI)".

Pinato DJ, Stebbing J, Ishizuka M, Khan SA, Wasan HS, North BV, Kubota K, Sharma R.

J Hepatol. 2016 Jun 16. pii: S0168-8278(16)30205-7. doi: 10.1016/j.jhep.2016.05.019. [Epub ahead of print] No abstract available.


Validation of a contemporary prostate cancer grading system using prostate cancer death as outcome.

Berney DM, Beltran L, Fisher G, North BV, Greenberg D, Møller H, Soosay G, Scardino P, Cuzick J.

Br J Cancer. 2016 May 10;114(10):1078-83. doi: 10.1038/bjc.2016.86. Epub 2016 Apr 21.


Smurf1 regulation of DAB2IP controls cell proliferation and migration.

Li X, Dai X, Wan L, Inuzuka H, Sun L, North BJ.

Oncotarget. 2016 May 3;7(18):26057-69. doi: 10.18632/oncotarget.8424.


Differential introgression and reorganization of retrotransposons in hybrid zones between wild wheats.

Senerchia N, Felber F, North B, Sarr A, Guadagnuolo R, Parisod C.

Mol Ecol. 2016 Jun;25(11):2518-28. doi: 10.1111/mec.13515. Epub 2016 Feb 16.


Validation of an RNA cell cycle progression score for predicting death from prostate cancer in a conservatively managed needle biopsy cohort.

Cuzick J, Stone S, Fisher G, Yang ZH, North BV, Berney DM, Beltran L, Greenberg D, Møller H, Reid JE, Gutin A, Lanchbury JS, Brawer M, Scardino P.

Br J Cancer. 2015 Jul 28;113(3):382-9. doi: 10.1038/bjc.2015.223. Epub 2015 Jun 23.


Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

Rumpf T, Schiedel M, Karaman B, Roessler C, North BJ, Lehotzky A, Oláh J, Ladwein KI, Schmidtkunz K, Gajer M, Pannek M, Steegborn C, Sinclair DA, Gerhardt S, Ovádi J, Schutkowski M, Sippl W, Einsle O, Jung M.

Nat Commun. 2015 Feb 12;6:6263. doi: 10.1038/ncomms7263.


Evaluation of a minimally invasive cell sampling device coupled with assessment of trefoil factor 3 expression for diagnosing Barrett's esophagus: a multi-center case-control study.

Ross-Innes CS, Debiram-Beecham I, O'Donovan M, Walker E, Varghese S, Lao-Sirieix P, Lovat L, Griffin M, Ragunath K, Haidry R, Sami SS, Kaye P, Novelli M, Disep B, Ostler R, Aigret B, North BV, Bhandari P, Haycock A, Morris D, Attwood S, Dhar A, Rees C, Rutter MD, Sasieni PD, Fitzgerald RC; BEST2 Study Group.

PLoS Med. 2015 Jan 29;12(1):e1001780. doi: 10.1371/journal.pmed.1001780. eCollection 2015 Jan.


A telephone reminder intervention to improve breast screening information and access.

Offman J, Myles J, Ariyanayagam S, Colorado Z, Sharp M, Cruice M, North BV, Shiel S, Baker T, Jefferies R, Binysh K, Duffy SW.

Public Health. 2014 Nov;128(11):1017-22. doi: 10.1016/j.puhe.2014.09.007. Epub 2014 Nov 18.


PyIgClassify: a database of antibody CDR structural classifications.

Adolf-Bryfogle J, Xu Q, North B, Lehmann A, Dunbrack RL Jr.

Nucleic Acids Res. 2015 Jan;43(Database issue):D432-8. doi: 10.1093/nar/gku1106. Epub 2014 Nov 11.


SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination.

Wu X, Fukushima H, North BJ, Nagaoka Y, Nagashima K, Deng F, Okabe K, Inuzuka H, Wei W.

Oncotarget. 2014 Jun 30;5(12):4211-21.


Negative regulation of DAB2IP by Akt and SCFFbw7 pathways.

Dai X, North BJ, Inuzuka H.

Oncotarget. 2014 May 30;5(10):3307-15.


SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

North BJ, Rosenberg MA, Jeganathan KB, Hafner AV, Michan S, Dai J, Baker DJ, Cen Y, Wu LE, Sauve AA, van Deursen JM, Rosenzweig A, Sinclair DA.

EMBO J. 2014 Jul 1;33(13):1438-53. doi: 10.15252/embj.201386907. Epub 2014 May 12.


Dialysate cytokine levels do not predict encapsulating peritoneal sclerosis.

Goodlad C, Tam FW, Ahmad S, Bhangal G, North BV, Brown EA.

Perit Dial Int. 2014 Sep-Oct;34(6):594-604. doi: 10.3747/pdi.2012.00305. Epub 2014 Mar 1.


Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

Bonezzi K, Belotti D, North BJ, Ghilardi C, Borsotti P, Resovi A, Ubezio P, Riva A, Giavazzi R, Verdin E, Taraboletti G.

Neoplasia. 2012 Sep;14(9):846-54.


Relationship between price paid for off-trade alcohol, alcohol consumption and income in England: a cross-sectional survey.

Crawford MJ, Parry AM, Weston AR, Seretis D, Zauter-Tutt M, Hussain A, Mostajabi P, Sanatinia R, North B.

Alcohol Alcohol. 2012 Nov-Dec;47(6):738-42. doi: 10.1093/alcalc/ags091. Epub 2012 Aug 14.


A novel and validated prognostic index in hepatocellular carcinoma: the inflammation based index (IBI).

Pinato DJ, Stebbing J, Ishizuka M, Khan SA, Wasan HS, North BV, Kubota K, Sharma R.

J Hepatol. 2012 Nov;57(5):1013-20. doi: 10.1016/j.jhep.2012.06.022. Epub 2012 Jun 23.


Survival of women with gestational trophoblastic neoplasia and liver metastases: is it improving?

Ahamed E, Short D, North B, Savage PM, Seckl MJ.

J Reprod Med. 2012 May-Jun;57(5-6):262-9.


Validation of the isovolumetric relaxation time for the estimation of pulmonary systolic arterial blood pressure in chronic pulmonary hypertension.

Zimbarra Cabrita I, Ruísanchez C, Grapsa J, Dawson D, North B, Pinto FJ, Gibbs JS, Nihoyannopoulos P.

Eur Heart J Cardiovasc Imaging. 2013 Jan;14(1):51-5. doi: 10.1093/ehjci/jes093. Epub 2012 May 15.


SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA.

Cell Metab. 2012 May 2;15(5):675-90. doi: 10.1016/j.cmet.2012.04.003.


Computational design of a protein crystal.

Lanci CJ, MacDermaid CM, Kang SG, Acharya R, North B, Yang X, Qiu XJ, DeGrado WF, Saven JG.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7304-9. doi: 10.1073/pnas.1112595109. Epub 2012 Apr 25.


The intersection between aging and cardiovascular disease.

North BJ, Sinclair DA.

Circ Res. 2012 Apr 13;110(8):1097-108. doi: 10.1161/CIRCRESAHA.111.246876. Review.


A novel, externally validated inflammation-based prognostic algorithm in hepatocellular carcinoma: the prognostic nutritional index (PNI).

Pinato DJ, North BV, Sharma R.

Br J Cancer. 2012 Apr 10;106(8):1439-45. doi: 10.1038/bjc.2012.92. Epub 2012 Mar 20.


Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.

Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26.


Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer.

Watanabe Y, Castoro RJ, Kim HS, North B, Oikawa R, Hiraishi T, Ahmed SS, Chung W, Cho MY, Toyota M, Itoh F, Estecio MR, Shen L, Jelinek J, Issa JP.

PLoS One. 2011;6(8):e23320. doi: 10.1371/journal.pone.0023320. Epub 2011 Aug 11.

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