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Items: 1 to 50 of 59

1.

Congenital Heart Disease: In Search of Remedial Etiologies.

Markwald RR, Ghatak S, Misra S, Moreno-Rodríguez RA, Sugi Y, Norris RA.

In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 5.
2016 Jun 25.

2.

New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study.

Le Tourneau T, Le Scouarnec S, Cueff C, Bernstein D, Aalberts JJJ, Lecointe S, Mérot J, Bernstein JA, Oomen T, Dina C, Karakachoff M, Desal H, Al Habash O, Delling FN, Capoulade R, Suurmeijer AJH, Milan D, Norris RA, Markwald R, Aikawa E, Slaugenhaupt SA, Jeunemaitre X, Hagège A, Roussel JC, Trochu JN, Levine RA, Kyndt F, Probst V, Le Marec H, Schott JJ.

Eur Heart J. 2018 Apr 14;39(15):1269-1277. doi: 10.1093/eurheartj/ehx505.

PMID:
29020406
3.

Inheritance Impacts Mitral Valve Insufficiency.

Judge DP, Norris RA.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001920. doi: 10.1161/CIRCGENETICS.117.001920. No abstract available.

PMID:
28993408
4.

The exocyst is required for photoreceptor ciliogenesis and retinal development.

Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH.

J Biol Chem. 2017 Sep 8;292(36):14814-14826. doi: 10.1074/jbc.M117.795674. Epub 2017 Jul 20.

PMID:
28729419
5.

A role for primary cilia in aortic valve development and disease.

Toomer KA, Fulmer D, Guo L, Drohan A, Peterson N, Swanson P, Brooks B, Mukherjee R, Body S, Lipschutz JH, Wessels A, Norris RA.

Dev Dyn. 2017 Aug;246(8):625-634. doi: 10.1002/dvdy.24524. Epub 2017 Jun 28.

6.

Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model.

Munjal C, Jegga AG, Opoka AM, Stoilov I, Norris RA, Thomas CJ, Smith JM, Mecham RP, Bressan GM, Hinton RB.

Physiol Rep. 2017 Mar;5(5). pii: e13152. doi: 10.14814/phy2.13152.

7.

Targeted Mybpc3 Knock-Out Mice with Cardiac Hypertrophy Exhibit Structural Mitral Valve Abnormalities.

Judge DP, Neamatalla H, Norris RA, Levine RA, Butcher JT, Vignier N, Kang KH, Nguyen Q, Bruneval P, Perier MC, Messas E, Jeunemaitre X, de Vlaming A, Markwald R, Carrier L, Hagège AA.

J Cardiovasc Dev Dis. 2015;2(2):48-65. Epub 2015 Apr 21.

8.

MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1.

Barnes RM, Harris IS, Jaehnig EJ, Sauls K, Sinha T, Rojas A, Schachterle W, McCulley DJ, Norris RA, Black BL.

Development. 2016 Mar 1;143(5):774-9. doi: 10.1242/dev.126383. Epub 2016 Jan 25.

9.

The Living Scar--Cardiac Fibroblasts and the Injured Heart.

Rog-Zielinska EA, Norris RA, Kohl P, Markwald R.

Trends Mol Med. 2016 Feb;22(2):99-114. doi: 10.1016/j.molmed.2015.12.006. Epub 2016 Jan 14. Review.

10.

Embryonic Development of the Bicuspid Aortic Valve.

Martin PS, Kloesel B, Norris RA, Lindsay M, Milan D, Body SC.

J Cardiovasc Dev Dis. 2015 Dec;2(4):248-272. doi: 10.3390/jcdd2040248. Epub 2015 Oct 2.

11.

MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions.

Duval D, Labbé P, Bureau L, Le Tourneau T, Norris RA, Markwald RR, Levine R, Schott JJ, Mérot J.

J Cardiovasc Dev Dis. 2015 Sep 8;2(3):233-247.

12.

Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and Disease.

Horne TE, VandeKopple M, Sauls K, Koenig SN, Anstine LJ, Garg V, Norris RA, Lincoln J.

J Cardiovasc Dev Dis. 2015 Sep;2(3):214-232. doi: 10.3390/jcdd2030214. Epub 2015 Aug 17.

13.

Mitral valve disease--morphology and mechanisms.

Levine RA, Hagége AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, Beaudoin J, Bischoff J, Bouatia-Naji N, Bruneval P, Butcher JT, Carpentier A, Chaput M, Chester AH, Clusel C, Delling FN, Dietz HC, Dina C, Durst R, Fernandez-Friera L, Handschumacher MD, Jensen MO, Jeunemaitre XP, Le Marec H, Le Tourneau T, Markwald RR, Mérot J, Messas E, Milan DP, Neri T, Norris RA, Peal D, Perrocheau M, Probst V, Pucéat M, Rosenthal N, Solis J, Schott JJ, Schwammenthal E, Slaugenhaupt SA, Song JK, Yacoub MH; Leducq Mitral Transatlantic Network.

Nat Rev Cardiol. 2015 Dec;12(12):689-710. doi: 10.1038/nrcardio.2015.161. Epub 2015 Oct 20. Review.

14.

Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease.

Sauls K, Toomer K, Williams K, Johnson AJ, Markwald RR, Hajdu Z, Norris RA.

J Cardiovasc Dev Dis. 2015 Sep;2(3):200-213. Epub 2015 Jul 24.

15.

Genetic association analyses highlight biological pathways underlying mitral valve prolapse.

Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J; PROMESA investigators, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA; MVP-France, Jeunemaitre X; Leducq Transatlantic MITRAL Network.

Nat Genet. 2015 Oct;47(10):1206-11. doi: 10.1038/ng.3383. Epub 2015 Aug 24.

16.

Mutations in DCHS1 cause mitral valve prolapse.

Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA.

Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10.

17.

Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction.

Lockhart MM, Boukens BJ, Phelps AL, Brown CL, Toomer KA, Burns TA, Mukherjee RD, Norris RA, Trusk TC, van den Hoff MJ, Wessels A.

Dev Biol. 2014 Dec 1;396(1):8-18. doi: 10.1016/j.ydbio.2014.09.031. Epub 2014 Oct 6.

18.

Periostin induces intracellular cross-talk between kinases and hyaluronan in atrioventricular valvulogenesis.

Ghatak S, Misra S, Norris RA, Moreno-Rodriguez RA, Hoffman S, Levine RA, Hascall VC, Markwald RR.

J Biol Chem. 2014 Mar 21;289(12):8545-61. doi: 10.1074/jbc.M113.539882. Epub 2014 Jan 27.

19.

Cadherin-11 expression patterns in heart valves associate with key functions during embryonic cushion formation, valve maturation and calcification.

Zhou J, Bowen C, Lu G, Knapp Iii C, Recknagel A, Norris RA, Butcher JT.

Cells Tissues Organs. 2013;198(4):300-10. doi: 10.1159/000356762. Epub 2013 Dec 20.

20.

Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.

Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC.

J Clin Invest. 2014 Jan;124(1):448-60. doi: 10.1172/JCI69666. Epub 2013 Dec 20.

21.

The effects of age and the expression of SPARC on extracellular matrix production by cardiac fibroblasts in 3-D cultures.

Trombetta-eSilva J, Eadie EP, Zhang Y, Norris RA, Borg TK, Bradshaw AD.

PLoS One. 2013 Nov 6;8(11):e79715. doi: 10.1371/journal.pone.0079715. eCollection 2013.

22.

Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation.

Duval D, Lardeux A, Le Tourneau T, Norris RA, Markwald RR, Sauzeau V, Probst V, Le Marec H, Levine R, Schott JJ, Merot J.

Biochim Biophys Acta. 2014 Feb;1843(2):234-44. doi: 10.1016/j.bbamcr.2013.10.022. Epub 2013 Nov 4.

23.

Distinct signaling pathways activated by "extracellular" and "intracellular" serotonin in heart valve development and disease.

Pavone LM, Norris RA.

Cell Biochem Biophys. 2013;67(3):819-28. doi: 10.1007/s12013-013-9606-8. Review.

PMID:
23605455
24.

miR-21 represses Pdcd4 during cardiac valvulogenesis.

Kolpa HJ, Peal DS, Lynch SN, Giokas AC, Ghatak S, Misra S, Norris RA, Macrae CA, Markwald RR, Ellinor P, Bischoff J, Milan DJ.

Development. 2013 May;140(10):2172-80. doi: 10.1242/dev.084475. Epub 2013 Apr 11.

25.

Four Square Step Test in ambulant persons with multiple sclerosis: validity, reliability, and responsiveness.

Wagner JM, Norris RA, Van Dillen LR, Thomas FP, Naismith RT.

Int J Rehabil Res. 2013 Sep;36(3):253-9. doi: 10.1097/MRR.0b013e32835fd97f.

PMID:
23511117
26.

Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.

Lockhart MM, Wirrig EE, Phelps AL, Ghatnekar AV, Barth JL, Norris RA, Wessels A.

PLoS One. 2013;8(2):e57073. doi: 10.1371/journal.pone.0057073. Epub 2013 Feb 26.

27.

Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm.

Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC.

Nat Genet. 2012 Nov;44(11):1249-54. doi: 10.1038/ng.2421. Epub 2012 Sep 30.

28.

Developmental basis for filamin-A-associated myxomatous mitral valve disease.

Sauls K, de Vlaming A, Harris BS, Williams K, Wessels A, Levine RA, Slaugenhaupt SA, Goodwin RL, Pavone LM, Merot J, Schott JJ, Le Tourneau T, Dix T, Jesinkey S, Feng Y, Walsh C, Zhou B, Baldwin S, Markwald RR, Norris RA.

Cardiovasc Res. 2012 Oct 1;96(1):109-19. doi: 10.1093/cvr/cvs238. Epub 2012 Jul 25.

29.

Atrioventricular valve development: new perspectives on an old theme.

de Vlaming A, Sauls K, Hajdu Z, Visconti RP, Mehesz AN, Levine RA, Slaugenhaupt SA, Hagège A, Chester AH, Markwald RR, Norris RA.

Differentiation. 2012 Jul;84(1):103-16. doi: 10.1016/j.diff.2012.04.001. Epub 2012 May 11. Review.

30.

Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart.

Wessels A, van den Hoff MJ, Adamo RF, Phelps AL, Lockhart MM, Sauls K, Briggs LE, Norris RA, van Wijk B, Perez-Pomares JM, Dettman RW, Burch JB.

Dev Biol. 2012 Jun 15;366(2):111-24. doi: 10.1016/j.ydbio.2012.04.020. Epub 2012 Apr 24.

31.

Expression and deposition of fibrous extracellular matrix proteins in cardiac valves during chick development.

Tan H, Junor L, Price RL, Norris RA, Potts JD, Goodwin RL.

Microsc Microanal. 2011 Feb;17(1):91-100. doi: 10.1017/S1431927610094365. Epub 2010 Dec 23.

32.

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG.

J Clin Invest. 2010 Oct;120(10):3520-9. doi: 10.1172/JCI42028. Epub 2010 Sep 1.

33.
34.

Tissue spheroid fusion-based in vitro screening assays for analysis of tissue maturation.

Hajdu Z, Mironov V, Mehesz AN, Norris RA, Markwald RR, Visconti RP.

J Tissue Eng Regen Med. 2010 Dec;4(8):659-64. doi: 10.1002/term.291.

35.

Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis.

Norris RA, Moreno-Rodriguez R, Wessels A, Merot J, Bruneval P, Chester AH, Yacoub MH, Hagège A, Slaugenhaupt SA, Aikawa E, Schott JJ, Lardeux A, Harris BS, Williams LK, Richards A, Levine RA, Markwald RR.

Dev Dyn. 2010 Jul;239(7):2118-27. doi: 10.1002/dvdy.22346.

36.

Comment on: developing good scientific publishing practices: one pharmaceutical company's perspective.

Norris RA.

Curr Med Res Opin. 2010 Jul;26(7):1675-6. doi: 10.1185/03007995.2010.487418. No abstract available.

PMID:
20450261
37.

Periostin is expressed by cells of the human and sand rat intervertebral discs.

Gruber HE, Norris RA, Kern MJ, Hoelscher GL, Ingram JA, Zinchenko N, Hanley EN Jr.

Biotech Histochem. 2011 Jun;86(3):199-206. doi: 10.3109/10520291003722774. Epub 2010 Apr 6.

PMID:
20370359
38.

Developmental basis of adult cardiovascular diseases: valvular heart diseases.

Markwald RR, Norris RA, Moreno-Rodriguez R, Levine RA.

Ann N Y Acad Sci. 2010 Feb;1188:177-83. doi: 10.1111/j.1749-6632.2009.05098.x. Review.

39.

The many facets of the matricelluar protein periostin during cardiac development, remodeling, and pathophysiology.

Norris RA, Moreno-Rodriguez R, Hoffman S, Markwald RR.

J Cell Commun Signal. 2009 Dec;3(3-4):275-86. doi: 10.1007/s12079-009-0063-5. Epub 2009 Oct 2.

40.

Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway.

Li G, Jin R, Norris RA, Zhang L, Yu S, Wu F, Markwald RR, Nanda A, Conway SJ, Smyth SS, Granger DN.

Atherosclerosis. 2010 Feb;208(2):358-65. doi: 10.1016/j.atherosclerosis.2009.07.046. Epub 2009 Jul 30.

41.

Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cells.

Norris RA, Potts JD, Yost MJ, Junor L, Brooks T, Tan H, Hoffman S, Hart MM, Kern MJ, Damon B, Markwald RR, Goodwin RL.

Dev Dyn. 2009 May;238(5):1052-63. doi: 10.1002/dvdy.21933.

42.

Neonatal and adult cardiovascular pathophysiological remodeling and repair: developmental role of periostin.

Norris RA, Borg TK, Butcher JT, Baudino TA, Banerjee I, Markwald RR.

Ann N Y Acad Sci. 2008 Mar;1123:30-40. doi: 10.1196/annals.1420.005.

PMID:
18375575
43.

Periostin regulates atrioventricular valve maturation.

Norris RA, Moreno-Rodriguez RA, Sugi Y, Hoffman S, Amos J, Hart MM, Potts JD, Goodwin RL, Markwald RR.

Dev Biol. 2008 Apr 15;316(2):200-13. doi: 10.1016/j.ydbio.2008.01.003. Epub 2008 Jan 17.

44.

The functional reach test in 3- to 5-year-old children without disabilities.

Norris RA, Wilder E, Norton J.

Pediatr Phys Ther. 2008 Spring;20(1):47-52. doi: 10.1097/PEP.0b013e31815ce63f.

PMID:
18300933
45.

BMP-2 induces cell migration and periostin expression during atrioventricular valvulogenesis.

Inai K, Norris RA, Hoffman S, Markwald RR, Sugi Y.

Dev Biol. 2008 Mar 15;315(2):383-96. doi: 10.1016/j.ydbio.2007.12.028. Epub 2007 Dec 31.

46.

Versican proteolysis mediates myocardial regression during outflow tract development.

Kern CB, Norris RA, Thompson RP, Argraves WS, Fairey SE, Reyes L, Hoffman S, Markwald RR, Mjaatvedt CH.

Dev Dyn. 2007 Mar;236(3):671-83. Erratum in: Dev Dyn. 2007 Apr;236(4):1157.

47.

Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues.

Norris RA, Damon B, Mironov V, Kasyanov V, Ramamurthi A, Moreno-Rodriguez R, Trusk T, Potts JD, Goodwin RL, Davis J, Hoffman S, Wen X, Sugi Y, Kern CB, Mjaatvedt CH, Turner DK, Oka T, Conway SJ, Molkentin JD, Forgacs G, Markwald RR.

J Cell Biochem. 2007 Jun 1;101(3):695-711.

48.

Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase.

Butcher JT, Norris RA, Hoffman S, Mjaatvedt CH, Markwald RR.

Dev Biol. 2007 Feb 1;302(1):256-66. Epub 2006 Oct 4.

49.

Detection of betaig-H3, a TGFbeta induced gene, during cardiac development and its complementary pattern with periostin.

Norris RA, Kern CB, Wessels A, Wirrig EE, Markwald RR, Mjaatvedt CH.

Anat Embryol (Berl). 2005 Aug;210(1):13-23. Epub 2005 Jul 21.

PMID:
16034610
50.

Normal distribution of melanocytes in the mouse heart.

Mjaatvedt CH, Kern CB, Norris RA, Fairey S, Cave CL.

Anat Rec A Discov Mol Cell Evol Biol. 2005 Aug;285(2):748-57.

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