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Items: 24

1.

Identification of proresolving and inflammatory lipid mediators in human psoriasis.

Sorokin AV, Norris PC, English JT, Dey AK, Chaturvedi A, Baumer Y, Silverman J, Playford MP, Serhan CN, Mehta NN.

J Clin Lipidol. 2018 Jul - Aug;12(4):1047-1060. doi: 10.1016/j.jacl.2018.03.091. Epub 2018 Apr 6.

PMID:
29730187
2.

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration.

de la Rosa X, Norris PC, Chiang N, Rodriguez AR, Spur BW, Serhan CN.

Am J Pathol. 2018 Apr;188(4):950-966. doi: 10.1016/j.ajpath.2018.01.004.

PMID:
29571326
3.

Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues.

Norris PC, Serhan CN.

Biochem Biophys Res Commun. 2018 Mar 15. pii: S0006-291X(18)30511-4. doi: 10.1016/j.bbrc.2018.03.037. [Epub ahead of print]

PMID:
29524409
4.

15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia.

Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD.

J Immunol. 2018 Apr 15;200(8):2757-2766. doi: 10.4049/jimmunol.1602090. Epub 2018 Mar 9.

PMID:
29523657
5.

Splenic leukocytes define the resolution of inflammation in heart failure.

Halade GV, Norris PC, Kain V, Serhan CN, Ingle KA.

Sci Signal. 2018 Mar 6;11(520). pii: eaao1818. doi: 10.1126/scisignal.aao1818.

PMID:
29511119
6.

Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation.

Winkler JW, Libreros S, De La Rosa X, Sansbury BE, Norris PC, Chiang N, Fichtner D, Keyes GS, Wourms N, Spite M, Serhan CN.

J Leukoc Biol. 2018 Jan 29. doi: 10.1002/JLB.3MI0617-254R. [Epub ahead of print]

PMID:
29377345
7.

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity.

Werz O, Gerstmeier J, Libreros S, De la Rosa X, Werner M, Norris PC, Chiang N, Serhan CN.

Nat Commun. 2018 Jan 4;9(1):59. doi: 10.1038/s41467-017-02538-5.

8.

Potent Anti-Inflammatory and Pro-Resolving Effects of Anabasum in a Human Model of Self-Resolving Acute Inflammation.

Motwani MP, Bennett F, Norris PC, Maini AA, George MJ, Newson J, Henderson A, Hobbs AJ, Tepper M, White B, Serhan CN, MacAllister R, Gilroy DW.

Clin Pharmacol Ther. 2017 Dec 14. doi: 10.1002/cpt.980. [Epub ahead of print]

PMID:
29238967
9.

A cluster of immunoresolvents links coagulation to innate host defense in human blood.

Norris PC, Libreros S, Chiang N, Serhan CN.

Sci Signal. 2017 Aug 1;10(490). pii: eaan1471. doi: 10.1126/scisignal.aan1471.

10.

NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4 Synthesis.

Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon JS, Shinohara M, Hisata S, Howrylak JA, Suh GY, Ryter SW, Serhan CN, Choi AMK.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):713-726. doi: 10.1164/rccm.201604-0892OC.

PMID:
28245134
11.

Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics.

English JT, Norris PC, Hodges RR, Dartt DA, Serhan CN.

Prostaglandins Leukot Essent Fatty Acids. 2017 Feb;117:17-27. doi: 10.1016/j.plefa.2017.01.004. Epub 2017 Jan 19.

12.

Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension.

Liu F, Haeger CM, Dieffenbach PB, Sicard D, Chrobak I, Coronata AM, Suárez Velandia MM, Vitali S, Colas RA, Norris PC, Marinković A, Liu X, Ma J, Rose CD, Lee SJ, Comhair SA, Erzurum SC, McDonald JD, Serhan CN, Walsh SR, Tschumperlin DJ, Fredenburgh LE.

JCI Insight. 2016 Jun 2;1(8). pii: e86987.

13.

Computational Modeling of Competitive Metabolism between ω3- and ω6-Polyunsaturated Fatty Acids in Inflammatory Macrophages.

Gupta S, Kihara Y, Maurya MR, Norris PC, Dennis EA, Subramaniam S.

J Phys Chem B. 2016 Aug 25;120(33):8346-53. doi: 10.1021/acs.jpcb.6b02036. Epub 2016 Apr 26.

14.

Resolvin D3 multi-level proresolving actions are host protective during infection.

Norris PC, Arnardottir H, Sanger JM, Fichtner D, Keyes GS, Serhan CN.

Prostaglandins Leukot Essent Fatty Acids. 2016 Jan 22. pii: S0952-3278(15)30052-1. doi: 10.1016/j.plefa.2016.01.001. [Epub ahead of print]

15.

Eicosanoid storm in infection and inflammation.

Dennis EA, Norris PC.

Nat Rev Immunol. 2015 Aug;15(8):511-23. doi: 10.1038/nri3859. Epub 2015 Jul 3. Review. Erratum in: Nat Rev Immunol. 2015 Nov;15(11):724.

16.

Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways.

Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN.

FASEB J. 2015 May;29(5):2120-36. doi: 10.1096/fj.14-268441. Epub 2015 Feb 20.

17.

Phospholipase A2 regulates eicosanoid class switching during inflammasome activation.

Norris PC, Gosselin D, Reichart D, Glass CK, Dennis EA.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12746-51. doi: 10.1073/pnas.1404372111. Epub 2014 Aug 19.

18.

Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer.

Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR.

Mol Cancer Res. 2014 Nov;12(11):1677-88. doi: 10.1158/1541-7786.MCR-14-0397-T. Epub 2014 Jul 25.

19.

A lipidomic perspective on inflammatory macrophage eicosanoid signaling.

Norris PC, Dennis EA.

Adv Biol Regul. 2014 Jan;54:99-110. doi: 10.1016/j.jbior.2013.09.009. Epub 2013 Sep 25. Review.

20.

Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia.

Gregus AM, Dumlao DS, Wei SC, Norris PC, Catella LC, Meyerstein FG, Buczynski MW, Steinauer JJ, Fitzsimmons BL, Yaksh TL, Dennis EA.

FASEB J. 2013 May;27(5):1939-49. doi: 10.1096/fj.12-217414. Epub 2013 Feb 4.

21.

Dietary fish oil substitution alters the eicosanoid profile in ankle joints of mice during Lyme infection.

Dumlao DS, Cunningham AM, Wax LE, Norris PC, Hanks JH, Halpin R, Lett KM, Blaho VA, Mitchell WJ, Fritsche KL, Dennis EA, Brown CR.

J Nutr. 2012 Aug;142(8):1582-9. doi: 10.3945/jn.112.157883. Epub 2012 Jun 13.

22.

Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling.

Norris PC, Dennis EA.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8517-22. doi: 10.1073/pnas.1200189109. Epub 2012 May 14.

23.

High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines.

Dumlao DS, Buczynski MW, Norris PC, Harkewicz R, Dennis EA.

Biochim Biophys Acta. 2011 Nov;1811(11):724-36. doi: 10.1016/j.bbalip.2011.06.005. Epub 2011 Jun 13.

24.

Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype.

Norris PC, Reichart D, Dumlao DS, Glass CK, Dennis EA.

J Leukoc Biol. 2011 Sep;90(3):563-74. doi: 10.1189/jlb.0311153. Epub 2011 Jun 7.

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