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Items: 1 to 50 of 208

1.

Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata.

Barbulescu CC, Goldstein NB, Roop DR, Norris DA, Birlea SA.

J Invest Dermatol. 2019 Jun 10. pii: S0022-202X(19)31465-4. doi: 10.1016/j.jid.2019.03.1142. [Epub ahead of print] Review.

PMID:
31196751
2.

Targeting Huntingtin Expression in Patients with Huntington's Disease.

Tabrizi SJ, Leavitt BR, Landwehrmeyer GB, Wild EJ, Saft C, Barker RA, Blair NF, Craufurd D, Priller J, Rickards H, Rosser A, Kordasiewicz HB, Czech C, Swayze EE, Norris DA, Baumann T, Gerlach I, Schobel SA, Paz E, Smith AV, Bennett CF, Lane RM; Phase 1–2a IONIS-HTTRx Study Site Teams.

N Engl J Med. 2019 Jun 13;380(24):2307-2316. doi: 10.1056/NEJMoa1900907. Epub 2019 May 6.

PMID:
31059641
3.

2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis).

Welink J, Xu Y, Yang E, Wilson A, Henderson N, Luo L, Fraser S, Kavita U, Musuku A, James C, Fraier D, Zhang Y, Goykhman D, Summerfield S, Woolf E, Verhaeghe T, Hughes N, Behling A, Brown K, Bulychev A, Buonarati M, Cherry E, Cho SJ, Cludts I, Dillen L, Dodge R, Edmison A, Garofolo F, Green R, Haidar S, Hottenstein C, Ishii-Watabe A, Jang HG, Ji A, Jones B, Kassim S, Ma M, Lima Santos GM, Norris DA, Owen T, Piccoli S, Ramanathan R, Röhl I, Rosenbaum AI, Saito Y, Sangster T, Savoie N, Stebbins C, Sydor J, de Merbel NV, Verthelyi D, Vinter S, Whale E.

Bioanalysis. 2018 Nov 1;10(22):1781-1801. doi: 10.4155/bio-2018-0268. Epub 2018 Nov 29.

4.

High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata.

de Jong A, Jabbari A, Dai Z, Xing L, Lee D, Li MM, Duvic M, Hordinsky M, Norris DA, Price V, Mackay-Wiggan J, Clynes R, Christiano AM.

JCI Insight. 2018 Oct 4;3(19). pii: 121949. doi: 10.1172/jci.insight.121949.

5.

Frontiers in pigment cell and melanoma research.

Filipp FV, Birlea S, Bosenberg MW, Brash D, Cassidy PB, Chen S, D'Orazio JA, Fujita M, Goh BK, Herlyn M, Indra AK, Larue L, Leachman SA, Le Poole C, Liu-Smith F, Manga P, Montoliu L, Norris DA, Shellman Y, Smalley KSM, Spritz RA, Sturm RA, Swetter SM, Terzian T, Wakamatsu K, Weber JS, Box NF.

Pigment Cell Melanoma Res. 2018 Nov;31(6):728-735. doi: 10.1111/pcmr.12728. Epub 2018 Oct 3.

6.

BH3 mimetics induce apoptosis independent of DRP-1 in melanoma.

Mukherjee N, Strosnider A, Vagher B, Lambert KA, Slaven S, Robinson WA, Amato CM, Couts KL, Bemis JGT, Turner JA, Norris DA, Shellman YG.

Cell Death Dis. 2018 Sep 5;9(9):907. doi: 10.1038/s41419-018-0932-z.

7.

A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.

Biliouris K, Gaitonde P, Yin W, Norris DA, Wang Y, Henry S, Fey R, Nestorov I, Schmidt S, Rogge M, Lesko LJ, Trame MN.

CPT Pharmacometrics Syst Pharmacol. 2018 Sep;7(9):581-592. doi: 10.1002/psp4.12323. Epub 2018 Aug 16.

8.

CPP-E1A fusion peptides inhibit CtBP-mediated transcriptional repression.

Blevins MA, Zhang C, Zhang L, Li H, Li X, Norris DA, Huang M, Zhao R.

Mol Oncol. 2018 Aug;12(8):1358-1373. doi: 10.1002/1878-0261.12330. Epub 2018 Jun 23.

9.

Performance of a computer-aided digital dermoscopic image analyzer for melanoma detection in 1,076 pigmented skin lesion biopsies.

Del Rosario F, Farahi JM, Drendel J, Buntinx-Krieg T, Caravaglio J, Domozych R, Chapman S, Braunberger T, Dellavalle RP, Norris DA, Fathi R, Alkousakis T.

J Am Acad Dermatol. 2018 May;78(5):927-934.e6. doi: 10.1016/j.jaad.2017.01.049.

PMID:
29678380
10.

Alopecia areata is a medical disease.

Korta DZ, Christiano AM, Bergfeld W, Duvic M, Ellison A, Fu J, Harris JE, Hordinsky MK, King B, Kranz D, Mackay-Wiggan J, McMichael A, Norris DA, Price V, Shapiro J, Atanaskova Mesinkovska N.

J Am Acad Dermatol. 2018 Apr;78(4):832-834. doi: 10.1016/j.jaad.2017.09.011. No abstract available.

PMID:
29548423
11.

Dermatology training across the globe, part II: a summary of the literature.

Ashack KA, Burton KA, Barber C, St Claire K, Mounessa J, Dunnick CA, Norris DA, Dellavalle RP.

Br J Dermatol. 2018 Jun;178(6):1460-1461. doi: 10.1111/bjd.16465. Epub 2018 Apr 16. No abstract available.

PMID:
29451700
12.

Current State of Research and Summary of Preceding Summits.

Norris DA.

J Investig Dermatol Symp Proc. 2018 Jan;19(1):S1-S2. doi: 10.1016/j.jisp.2017.10.011.

13.

Assessment of the Drug Interaction Potential of Unconjugated and GalNAc3-Conjugated 2'-MOE-ASOs.

Shemesh CS, Yu RZ, Warren MS, Liu M, Jahic M, Nichols B, Post N, Lin S, Norris DA, Hurh E, Huang J, Watanabe T, Henry SP, Wang Y.

Mol Ther Nucleic Acids. 2017 Dec 15;9:34-47. doi: 10.1016/j.omtn.2017.08.012. Epub 2017 Aug 30.

14.

Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the β-Catenin Pathway in the Hair Follicle Bulge Stem Cells.

Goldstein NB, Koster MI, Jones KL, Gao B, Hoaglin LG, Robinson SE, Wright MJ, Birlea SI, Luman A, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA.

J Invest Dermatol. 2018 Mar;138(3):657-668. doi: 10.1016/j.jid.2017.09.040. Epub 2017 Oct 17.

15.

Inaccuracies in SEER registry data on melanoma thickness.

Mayer JE, Fathi R, Norris DA.

J Am Acad Dermatol. 2017 Jul;77(1):e17. doi: 10.1016/j.jaad.2017.01.061. No abstract available.

PMID:
28619572
16.

INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J.

Oncogene. 2017 Aug 31;36(35):4997-5005. doi: 10.1038/onc.2017.117. Epub 2017 May 1.

17.

Population Pharmacokinetics of Nusinersen in the Cerebral Spinal Fluid and Plasma of Pediatric Patients With Spinal Muscular Atrophy Following Intrathecal Administrations.

Luu KT, Norris DA, Gunawan R, Henry S, Geary R, Wang Y.

J Clin Pharmacol. 2017 Aug;57(8):1031-1041. doi: 10.1002/jcph.884. Epub 2017 Mar 29.

PMID:
28369979
18.

Repigmentation through Melanocyte Regeneration in Vitiligo.

Birlea SA, Goldstein NB, Norris DA.

Dermatol Clin. 2017 Apr;35(2):205-218. doi: 10.1016/j.det.2016.11.015. Review.

PMID:
28317529
19.

NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma.

Zhai Z, Liu W, Kaur M, Luo Y, Domenico J, Samson JM, Shellman YG, Norris DA, Dinarello CA, Spritz RA, Fujita M.

Oncogene. 2017 Jul 6;36(27):3820-3830. doi: 10.1038/onc.2017.26. Epub 2017 Mar 6.

20.

Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization.

Birlea SA, Costin GE, Roop DR, Norris DA.

Med Res Rev. 2017 Jul;37(4):907-935. doi: 10.1002/med.21426. Epub 2016 Dec 28. Review.

21.

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study.

Finkel RS, Chiriboga CA, Vajsar J, Day JW, Montes J, De Vivo DC, Yamashita M, Rigo F, Hung G, Schneider E, Norris DA, Xia S, Bennett CF, Bishop KM.

Lancet. 2016 Dec 17;388(10063):3017-3026. doi: 10.1016/S0140-6736(16)31408-8. Epub 2016 Dec 7.

PMID:
27939059
22.

Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.

Mukherjee N, Almeida A, Partyka KA, Lu Y, Schwan JV, Lambert K, Rogers M, Robinson WA, Robinson SE, Applegate AJ, Amato CM, Luo Y, Fujita M, Norris DA, Shellman YG.

Oncotarget. 2016 Dec 20;7(51):84594-84607. doi: 10.18632/oncotarget.13141.

23.

Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection.

Goldstein NB, Koster MI, Hoaglin LG, Wright MJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA.

Exp Dermatol. 2016 Oct;25(10):805-11. doi: 10.1111/exd.13072.

24.

Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells.

Mukherjee N, Lu Y, Almeida A, Lambert K, Shiau CW, Su JC, Luo Y, Fujita M, Robinson WA, Robinson SE, Norris DA, Shellman YG.

Oncotarget. 2017 Jul 18;8(29):46801-46817. doi: 10.18632/oncotarget.8695.

25.

Results from a phase 1 study of nusinersen (ISIS-SMN(Rx)) in children with spinal muscular atrophy.

Chiriboga CA, Swoboda KJ, Darras BT, Iannaccone ST, Montes J, De Vivo DC, Norris DA, Bennett CF, Bishop KM.

Neurology. 2016 Mar 8;86(10):890-7. doi: 10.1212/WNL.0000000000002445. Epub 2016 Feb 10.

26.

Overview of AA and Research Progress: What Have We Learned and Where Are We Headed?

Norris DA.

J Investig Dermatol Symp Proc. 2015 Nov;17(2):6-8. doi: 10.1038/jidsymp.2015.30. Review.

27.

From Targets to Treatments: Bridging Autoimmune Research to Advance Understanding of Alopecia Areata.

Kranz D, Ellison A, Frelinger JA, Mackay-Wiggan J, Norris DA.

J Investig Dermatol Symp Proc. 2015 Nov;17(2):1-5. doi: 10.1038/jidsymp.2015.29.

28.

SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype.

Shellman YG, Lambert KA, Brauweiler A, Fain P, Spritz RA, Martini M, Janssen KP, Box NF, Terzian T, Rewers M, Horvath A, Stratakis CA, Robinson WA, Robinson SE, Norris DA, Artinger KB, Pacheco TR.

J Invest Dermatol. 2015 Dec;135(12):3192-3194. doi: 10.1038/jid.2015.292. Epub 2015 Jul 23. No abstract available.

29.

Alternative Treatments For Melanoma: Targeting BCL-2 Family Members to De-Bulk and Kill Cancer Stem Cells.

Mukherjee N, Schwan JV, Fujita M, Norris DA, Shellman YG.

J Invest Dermatol. 2015 Sep;135(9):2155-2161. doi: 10.1038/jid.2015.145. Epub 2015 May 7. Review.

30.

Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors.

Goldstein NB, Koster MI, Hoaglin LG, Spoelstra NS, Kechris KJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA.

J Invest Dermatol. 2015 Aug;135(8):2068-2076. doi: 10.1038/jid.2015.126. Epub 2015 Mar 30.

31.

Heavy metal and nitrogen concentrations in mosses are declining across Europe whilst some "hotspots" remain in 2010.

Harmens H, Norris DA, Sharps K, Mills G, Alber R, Aleksiayenak Y, Blum O, Cucu-Man SM, Dam M, De Temmerman L, Ene A, Fernández JA, Martinez-Abaigar J, Frontasyeva M, Godzik B, Jeran Z, Lazo P, Leblond S, Liiv S, Magnússon SH, Maňkovská B, Karlsson GP, Piispanen J, Poikolainen J, Santamaria JM, Skudnik M, Spiric Z, Stafilov T, Steinnes E, Stihi C, Suchara I, Thöni L, Todoran R, Yurukova L, Zechmeister HG.

Environ Pollut. 2015 May;200:93-104. doi: 10.1016/j.envpol.2015.01.036. Epub 2015 Feb 18.

PMID:
25703579
32.

Predictive dose-based estimation of systemic exposure multiples in mouse and monkey relative to human for antisense oligonucleotides with 2'-o-(2-methoxyethyl) modifications.

Yu RZ, Grundy JS, Henry SP, Kim TW, Norris DA, Burkey J, Wang Y, Vick A, Geary RS.

Mol Ther Nucleic Acids. 2015 Jan 20;4:e218. doi: 10.1038/mtna.2014.69.

33.

The global burden of disease associated with alopecia areata.

Karimkhani C, Boyers LN, Naghavi M, Coffeng LE, Lott JP, Wulf S, Hay R, Williams HC, Weinstock MA, Norton SA, Armstrong AW, Dunnick CA, Norris DA, Dellavalle RP.

Br J Dermatol. 2015;172(5):1424-6. doi: 10.1111/bjd.13559. Epub 2015 Mar 18. No abstract available.

PMID:
25422028
34.

Combining a BCL2 inhibitor with the retinoid derivative fenretinide targets melanoma cells including melanoma initiating cells.

Mukherjee N, Reuland SN, Lu Y, Luo Y, Lambert K, Fujita M, Robinson WA, Robinson SE, Norris DA, Shellman YG.

J Invest Dermatol. 2015 Mar;135(3):842-850. doi: 10.1038/jid.2014.464. Epub 2014 Oct 28.

35.

Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates.

Rigo F, Chun SJ, Norris DA, Hung G, Lee S, Matson J, Fey RA, Gaus H, Hua Y, Grundy JS, Krainer AR, Henry SP, Bennett CF.

J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30.

36.

George W. Hambrick Jr (1922-2013).

Norris DA.

J Invest Dermatol. 2014 May;134(5):1190-1191. doi: 10.1038/jid.2014.125. No abstract available.

37.

The national alopecia areata registry-update.

Duvic M, Christiano AM, Hordinsky MK, Norris DA, Price VH, Amos CI.

J Investig Dermatol Symp Proc. 2013 Dec;16(1):S53. doi: 10.1038/jidsymp.2013.20. No abstract available.

38.

Summary of the preceding three alopecia areata research summits: what's past is prologue.

Norris DA.

J Investig Dermatol Symp Proc. 2013 Dec;16(1):S5-9. doi: 10.1038/jidsymp.2013.2. No abstract available.

39.

Health-Related Quality of Life (HRQoL) in alopecia areata patients-a secondary analysis of the National Alopecia Areata Registry Data.

Shi Q, Duvic M, Osei JS, Hordinsky MK, Norris DA, Price VH, Amos CI, Christiano AM, Mendoza TR.

J Investig Dermatol Symp Proc. 2013 Dec;16(1):S49-50. doi: 10.1038/jidsymp.2013.18.

40.

Genes and immune response in alopecia areata: review of the alopecia areata research summit first day proceedings.

Norris DA.

J Investig Dermatol Symp Proc. 2013 Dec;16(1):S10-2. doi: 10.1038/jidsymp.2013.3. No abstract available.

41.

miR in melanoma development: miRNAs and acquired hallmarks of cancer in melanoma.

Bennett PE, Bemis L, Norris DA, Shellman YG.

Physiol Genomics. 2013 Nov 15;45(22):1049-59. doi: 10.1152/physiolgenomics.00116.2013. Epub 2013 Sep 17. Review.

42.

Biphasic pro-melanogenic and pro-apoptotic effects of all-trans-retinoic acid (ATRA) on human melanocytes: time-course study.

Baldea I, Costin GE, Shellman Y, Kechris K, Olteanu ED, Filip A, Cosgarea MR, Norris DA, Birlea SA.

J Dermatol Sci. 2013 Nov;72(2):168-76. doi: 10.1016/j.jdermsci.2013.06.004. Epub 2013 Jun 21.

PMID:
23867358
43.

Preclinical evaluation of the toxicological effects of a novel constrained ethyl modified antisense compound targeting signal transducer and activator of transcription 3 in mice and cynomolgus monkeys.

Burel SA, Han SR, Lee HS, Norris DA, Lee BS, Machemer T, Park SY, Zhou T, He G, Kim Y, MacLeod AR, Monia BP, Lio S, Kim TW, Henry SP.

Nucleic Acid Ther. 2013 Jun;23(3):213-27. doi: 10.1089/nat.2013.0422.

PMID:
23692080
44.

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study.

Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, Crisp M, Smith R, Bennett CF, Bishop KM, Cudkowicz ME.

Lancet Neurol. 2013 May;12(5):435-42. doi: 10.1016/S1474-4422(13)70061-9. Epub 2013 Mar 29. Erratum in: Lancet Neurol. 2013 May;12(5):423.

45.

Novel cutaneous effects of combination chemotherapy with BRAF and MEK inhibitors: a report of two cases.

Green JS, Norris DA, Wisell J.

Br J Dermatol. 2013 Jul;169(1):172-6. doi: 10.1111/bjd.12279.

PMID:
23413975
46.

CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1.

Deng H, Liu J, Deng Y, Han G, Shellman YG, Robinson SE, Tentler JJ, Robinson WA, Norris DA, Wang XJ, Zhang Q.

J Invest Dermatol. 2013 May;133(5):1294-301. doi: 10.1038/jid.2012.487. Epub 2013 Jan 10.

47.

Combined anti-tumor necrosis factor-α therapy and DMARD therapy in rheumatoid arthritis patients reduces inflammatory gene expression in whole blood compared to DMARD therapy alone.

Edwards CK 3rd, Green JS, Volk HD, Schiff M, Kotzin BL, Mitsuya H, Kawaguchi T, Sakata KM, Cheronis J, Trollinger D, Bankaitis-Davis D, Dinarello CA, Norris DA, Bevilacqua MP, Fujita M, Burmester GR.

Front Immunol. 2012 Dec 4;3:366. doi: 10.3389/fimmu.2012.00366. eCollection 2012.

48.

ABT-737 synergizes with Bortezomib to kill melanoma cells.

Reuland SN, Goldstein NB, Partyka KA, Smith S, Luo Y, Fujita M, Gonzalez R, Lewis K, Norris DA, Shellman YG.

Biol Open. 2012 Feb 15;1(2):92-100. doi: 10.1242/bio.2011035. Epub 2011 Nov 16.

49.

MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD).

Reuland SN, Smith SM, Bemis LT, Goldstein NB, Almeida AR, Partyka KA, Marquez VE, Zhang Q, Norris DA, Shellman YG.

J Invest Dermatol. 2013 May;133(5):1286-93. doi: 10.1038/jid.2012.400. Epub 2012 Nov 29.

50.

Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.

Liu W, Luo Y, Dunn JH, Norris DA, Dinarello CA, Fujita M.

J Invest Dermatol. 2013 Feb;133(2):518-27. doi: 10.1038/jid.2012.317. Epub 2012 Aug 30.

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